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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44394   clinical trials with a EudraCT protocol, of which   7406   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    2,397 result(s) found. Displaying page 1 of 120.
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    EudraCT Number: 2007-003370-26 Sponsor Protocol Number: CLAF237ADE03 Start Date*: 2007-11-15
    Sponsor Name:Charite Universitätsmedizin Berlin
    Full Title: A prospective, single center, double blind, placebo controlled study of adipocytokines, adipose tissue gene expression and hepatic insulin clearance in the therapeutic response to vildagliptin in man
    Medical condition: This is a single center, randomized, double-blind pilot study on patients with Type 2 diabetes. The purpose of this study is to test the effects of vildagliptin (as add-on to metformin) on hepatic ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005531-17 Sponsor Protocol Number: Xe-01 Start Date*: 2007-05-08
    Sponsor Name:Klinik für Anästhesiologie Universitätsklinikum Aachen
    Full Title: Xenon als Antidepressivum
    Medical condition: Major depressive disorder and recurrent mayor depressive disorder (ICD 10 F32.2 and 33.3)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000569-13 Sponsor Protocol Number: EMR 64300-608 Start Date*: 2006-04-21
    Sponsor Name:Cardioangiologisches Centrum Bethanien
    Full Title: Influence on the coronary Microcirculation and on myocArdial perfusion Reserve of Niaspan given IN addition to simvastatin in diabEtic patients
    Medical condition: Diabetic patients at high risk for CVD
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002278-37 Sponsor Protocol Number: panto001 Start Date*: 2008-08-12
    Sponsor Name:Johann Wolfgang Goethe Universität
    Full Title: Auswirkungen von Pantoprazol auf die myokardiale Kontraktilität bei Patienten mit Herzinsuffizienz - influence of pantoprazole on human myocardial contractility at patients with congestive heart fa...
    Medical condition: Recently literature revealed facts, that show H+/K+ ATPase expression is not limited tot he stomach. H+/K+ ATPase was also found in smooth muscle cells and in other tissues (McCabe, R.D. et al., Am...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002284-13 Sponsor Protocol Number: CRx-197-003 Start Date*: 2009-01-19
    Sponsor Name:CombinatoRx, Incorporated
    Full Title: A MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, CONTROLLED STUDY TO ASSESS THE ANTI-INFLAMMATORY PROPERTIES OF TOPICAL CRX-197 IN LESIONAL SKIN OF ADULT SUBJECTS WITH MILD TO MODERATE ATOPIC DERMATITIS
    Medical condition: mild to moderate atopic dermatitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003116-22 Sponsor Protocol Number: RBK091 Start Date*: 2006-12-21
    Sponsor Name:Prof. Sechtem, Department of Cardiology, Robert Bosch Hospital
    Full Title: Application of Sildenafil in patients with documented coronary vasospasm in order to explore the pathophysiology of coronary vasospasm and the therapeutic effects of Sildenafil in patients sufferin...
    Medical condition: Coronary vasospasm is an abrupt severe vasoconstriction of coronary arteries leading to myocardial ischemia and angina pectoris. The reason for the occurrence of coronary spasm and the cellular mec...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002501-72 Sponsor Protocol Number: Neo-WTS Start Date*: 2005-01-31
    Sponsor Name:
    Full Title: Studie zur neoadjuvanten Therapie bei Hochrisikopatienten mit Weichteilsarkom (STS) im Erwachsenenalter
    Medical condition: Weichteilsarkome im Erwachsenenalter
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000223-42 Sponsor Protocol Number: ZiSe Start Date*: 2005-10-31
    Sponsor Name:University Hospital Hamburg-Eppendorf, Psychiatry
    Full Title: Effects of ziprasidone vs. placebo during the first four weeks of eight weeks sertraline treatment in patients with posttraumatic stress disorder (PTSD)
    Medical condition: Post-traumatic Stress Disorder (PTSD) according to DSM-IV criteria
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-005060-24 Sponsor Protocol Number: Chirocain 2010 Start Date*: 2005-12-08
    Sponsor Name:Klinikum Leverkusen gGmbH
    Full Title: Comparison of Levobupivacaine and Ropivacaine for epidural application in obstetric gynaecology
    Medical condition: Comparison of Levobupivacaine and Ropivacaine for epidural application in obstetric gynaecology
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-005074-24 Sponsor Protocol Number: Feb-02 Start Date*: 2005-02-23
    Sponsor Name:Febena Pharma GmbH
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO INVESTIGATE THE EFFICACY AND SAFETY OF AN OINTMENT FORMULATION CONTAINING DEXAMETHASONE IN PATIENTS WITH RHINOSINUSITIS A CLINICAL PHASE IV ...
    Medical condition: Patients with allergy-induced, non-infectious diseases of the nasal mucosa (e. g. hay fever) and the sinuses.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10052106 Rhinosinusitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-005914-18 Sponsor Protocol Number: APIDR_L_00465 Start Date*: 2006-03-15
    Sponsor Name:Diabetes-Centre Quakenbrueck
    Full Title: Effect of Insulin Glulisin on postprandial plasma glucose levels in obese subjectts with type 2 diabetes after a standard meal in comparison to Insulin Lispro
    Medical condition: Obese subjects with type 2 diabetes mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002761-21 Sponsor Protocol Number: ADO-Solaraze-AK-3-6 Start Date*: 2005-08-08
    Sponsor Name:University Medical Center
    Full Title: RANDOMIZED, MULTICENTRE OPEN LABEL STUDY TO COMPARE THE EFFICACY AND TOLERABILITY OF SOLARAZE® FOR 3 MONTHS VERSUS 6 MONTHS IN PATIENTS WITH MILD TO MODERATE ACTINIC KERATOSIS LOCATED AT THE FACE A...
    Medical condition: Mild to moderate actinic keratoses located at the face and head
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001337-17 Sponsor Protocol Number: msuspio1muc Start Date*: 2007-09-25
    Sponsor Name:Max-Planck-Institute of Psychiatry
    Full Title: Characterisation of multiple sclerosis pathology by “ultra small particles of iron oxide (USPIO)” in comparison with conventional and advanced MRI imaging techniques [Charakterisierung der Multipl...
    Medical condition: Patients with Multiple Sclerosis (MS, N=90) and patients with a clinically isolated syndrome (ref. to as CIS in literature, i. e. not a clinically definite MS but a syndrome that may occur as first...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10028245 Multiple sclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001080-38 Sponsor Protocol Number: ANA 05108 G Start Date*: 2006-06-01
    Sponsor Name:Klinik für Anästhesiologie und Operative Intensivmedizin Klinikum Ludwigshafen
    Full Title: Einfluss einer fischölhaltigen Fettemulsion (SMOF®) auf die systemische immunologische Antwort, die Leberfunktion und die Utilisation bei parenteral ernährten Patienten auf einer chirurgischen Inte...
    Medical condition: Es werden Patienten im Alter > 18 Jahren auf einer chirurgischen Intensivstation, die parenteral ernährt werden müssen, in die Studie eingeschlossen. Ein spezielles Krankheitsbild liegt nicht vor, ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-006037-33 Sponsor Protocol Number: 150-05 Start Date*: 2006-08-09
    Sponsor Name:Universitätsklinikum Bonn; Klinik und Poliklinik für Psychiatrie und Psychotherapie
    Full Title: Überwachung einer Therapie mit Bromocriptin bei Patienten mit klinisch relevanter Risperidon-induzierter Hyperprolaktinämie. Eine psychiatrisch-endokrinologische Ver-laufsbeobachtung.
    Medical condition: Schizophrene Patienten mit einer Risperidon induzierten Hyperprolaktinämie
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002342-11 Sponsor Protocol Number: D1449L00033 Start Date*: 2007-04-19
    Sponsor Name:Klinikum Fulda gAG
    Full Title: Multicenter study of neurotransmitters and neuropeptides in schizophrenia: A multidisciplinary study of biological, pharmacokinetic, receptor occupancy and clinical relationships in patients suffer...
    Medical condition: Patients have to fulfill the diagnostic criteria of a schizophrenia according to DSM-IV.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017869-27 Sponsor Protocol Number: TERSSC-001 incl. Amendment 1 Start Date*: 2010-09-23
    Sponsor Name:University Hospital Zurich
    Full Title: A dual-center, open-label Proof of Concept study to evaluate the efficacy of Terguride for the treatment of fibrosis in patients with systemic sclerosis.
    Medical condition: Diffuse scleroderma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10012941 Diffuse scleroderma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002325-37 Sponsor Protocol Number: H80-MC-O008 Start Date*: 2008-07-08
    Sponsor Name:Department of Medicine I, University Hospital St. Josef-Hospital, Ruhr University Bochum
    Full Title: Effects of Exenatide (Byetta®) on biochemical and histological parameters of liver function in patients with Nonalcoholic Steatohepatitis (NASH) – a randomized, placebo-controlled, parallel-group t...
    Medical condition: Non alcoholic steatohepatitis (NASH)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10053219 Non-alcoholic steatohepatitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001069-32 Sponsor Protocol Number: D1449L0001 Start Date*: Information not available in EudraCT
    Sponsor Name:Psychosis Early Detection and Intervention Centre, Department for Psychiatry, UKE Hamburg
    Full Title: A prospective 8 weeks acute phase-IV study investigating efficacy, safety and tolerability of Quetiapine fumarate in 60 drug-naïve first-episode psychosis patients aged 18 to 35 years
    Medical condition: A prospective 8 weeks acute phase study investigating efficacy, safety and tolerability of Quetiapine fumarate in 60 drug-naïve first-episode psychosis patients aged 18 to 35 years.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000659-18 Sponsor Protocol Number: FumadermAA01 Start Date*: 2011-08-22
    Sponsor Name:University Hospital Tübingen
    Full Title: Treatment of therapy resistant Alopecia areata with fumaric acid esters (Fumaderm® and Fumaderm initial®) – an open, single center, non-randomized, pilot study with 40 patients
    Medical condition: Alopecia areata
    Disease: Version SOC Term Classification Code Term Level
    14.1 10040785 - Skin and subcutaneous tissue disorders 10001761 Alopecia areata PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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