Clinical trials

The European Union Clinical Trials Register allows you to search for protocol and results information on:

interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC

clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
Clinical Trials Information System (CTIS).

The EU Clinical Trials Register currently displays 44381 clinical trials with a EudraCT protocol, of which 7393 are clinical trials conducted with subjects less than 18 years old. The register also displays information on 18700 older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).

Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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Trials with a EudraCT protocol (10,987)
Paediatric studies in scope of Art45 of the Paediatric Regulation (0)

10,987 result(s) found. Displaying page 53 of 550.

EudraCT Number: 2005-004652-13	Sponsor Protocol Number: PSD502-PM-001	Start Date*: 2006-02-01
Sponsor Name:PLETHORA SOLUTIONS LIMITED
Full Title: Phase II, multi centre, randomised, double blind, placebo controlled, pilot study to determine efficacy, safety, tolerability and preliminary pharmacokinetics of PSD502 in the management of pain fr...
Medical condition: management of pain from donor sites in burns subjects undergoing skin grafts
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: GB (Prematurely Ended)
Trial results: (No results available)

EudraCT Number: 2006-001386-42	Sponsor Protocol Number: REC no:06/Q0403/25	Start Date*: 2006-07-06
Sponsor Name:Imperial College
Full Title: The timing of intra-vitreal (4mg) triamcinolone acetonide, in addition to verteporfin photodynamic therapy for choroidal neovascularisation, in age-related macular degeneration: a prospective rando...
Medical condition: Submacular choroidal neovascularisation in Age-related Macular Degeneration
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: GB (Completed)
Trial results: View results

EudraCT Number: 2007-000053-62

Sponsor Protocol Number: sph/itu/0001

Start Date*: 2007-06-18

Sponsor Name:Ashford & St. Peter's Hospitals NHS Trust

Full Title: The effects of helium-oxygen gas mixture (Heliox) on airway pressures in mechanically ventilated adult patients with acute lung injury

Medical condition: Acute lung injury

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10038696	Respiratory failure (excl neonatal)	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (GB - no longer in EU/EEA)

Trial results: (No results available)

EudraCT Number: 2007-000497-23

Sponsor Protocol Number: 07/Q0703/18

Start Date*: 2007-05-02

Sponsor Name:King's College Hospital NHS Foundation Trust [...]

Full Title: Do sulphponylureas preserve cortical function during hypoglycaemia in patients with type 1 diabetes and hypoglycaemia unawareness?

Medical condition: We are testing the hypothesis that closing the K ATP channels using sulphonylureas (glibenclamide) during experimental insulin induced hypoglycaemia can help retain cerebral function and help enhan...

Disease:	Version	SOC Term	Classification Code	Term	Level
	9.1		10020997	Hypoglycaemia unawareness	LLT
	9.1		10012608	Diabetes mellitus insulin-dependent	LLT

Population Age: Adults

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2006-001982-41

Sponsor Protocol Number: RAE04

Start Date*: 2006-10-03

Sponsor Name:Bradford Teaching Hospitals NHS Foundation Trust

Full Title: An evaluation of the safety and effectiveness of combination therapy using the thiazolidinedione pioglitazone alongside insulin in type 2 diabetes mellitus.

Medical condition: Type 2 Diabetes Mellitus

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	8.1		10012601	Diabetes mellitus	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: (No results available)

EudraCT Number: 2006-002208-32	Sponsor Protocol Number: PAR06	Start Date*: 2006-08-14
Sponsor Name:York Hospital NHS Trust
Full Title: A comparison of the analgesic efficacy of oral and intravenous paracetamol (perfalgan) in a day case setting
Medical condition: We will perform a double blind randomised comparison of oral paracetamol versus intravenous paracetamol (Perfalgan) in patients undergoing knee arthroscopy in a day surgery setting.
Disease:
Population Age: Adults		Gender: Male, Female
Trial protocol: GB (Prematurely Ended)
Trial results: View results

EudraCT Number: 2007-006761-32

Sponsor Protocol Number: A 091152

Start Date*: 2008-04-15

Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge

Full Title: Vulval intraepithelial neoplasia: immune responses to human papillpmavirus.

Medical condition: Vulval intraepithelial neoplasia

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10056574	Vulval intraepithelial neoplasia	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (GB - no longer in EU/EEA)

Trial results: (No results available)

EudraCT Number: 2006-001571-37

Sponsor Protocol Number: AAV2/2-hRPE65p-hRPE65

Start Date*: 2006-12-14

Sponsor Name:University College London

Full Title: AN OPEN-LABEL DOSE ESCALATION STUDY OF AN ADENO-ASSOCIATED VIRUS VECTOR (AAV2/2-hRPE65p-hRPE65) FOR GENE THERAPY OF SEVERE EARLY-ONSET RETINAL DEGENERATION

Medical condition: The condition to be investigated is severe early-onset inherited retinal degeneration due to defects in the gene encoding RPE65

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	13.1	10015919 - Eye disorders	10038845	Retinal degeneration	PT

Population Age: Children, Adolescents, Under 18, Adults

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2009-010956-93

Sponsor Protocol Number: HM09/8885

Start Date*: 2009-09-17

Sponsor Name:University of Leeds [...]

Full Title: Randomised comparisons, in myeloma patients of all ages, of thalidomide, lenalidomide, carfilzomib and bortezomib induction combinations, and of lenalidomide and combination lenalidomide vorinostat...

Medical condition: Newly diagnosed patients with symptomatic myeloma

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	16.0	100000004864	10028228	Multiple myeloma	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (GB - no longer in EU/EEA)

Trial results: (No results available)

EudraCT Number: 2008-008745-38

Sponsor Protocol Number: CKD-VitD-microcirc

Start Date*: 2009-04-08

Sponsor Name:Barts and the London NHS Trust

Full Title: THE EFFECT OF VITAMIN D ON THE MICROCIRCULATION OF PATIENTS WITH CHRONIC KIDNEY DISEASE AND VITAMIN D DEFICIENCY

Medical condition: Chronic kidney disease and vitamin D deficiency.

Disease:	Version	SOC Term	Classification Code	Term	Level
	9.1		10047626	Vitamin D deficiency	LLT
	9.1		10064848	Chronic kidney disease	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2006-006928-18

Sponsor Protocol Number: 06/Q0603/57

Start Date*: 2007-04-25

Sponsor Name:Barts and The London NHS Trust

Full Title: Randomised trial of Prontosan wound gel for prevention of exit site infection in peritoneal dialysis patients

Medical condition: Peritoneal dialysis patients and their peritoneal dialysis catheter exit site care.

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10008831	Chronic ambulatory peritoneal dialysis	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Prematurely Ended)

Trial results: View results

EudraCT Number: 2009-013100-32

Sponsor Protocol Number: pms.nov.001

Start Date*: 2009-12-01

Sponsor Name:University of Exeter [...]

Full Title: Does modulating the gut hormones, incretins, modify vascular function, thereby reducing the risk of vascular complications in insulin resistant individuals?

Medical condition: Obese (BMI equal or greater than 30) individuals at a high risk of diabetes, but without overt cardiovascular disease or taking oral hypoglycaemic, anti-hypetensive or lipid lowering therapies. Pur...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10029883	Obesity	LLT

Population Age: Adults

Gender: Male

Trial protocol: GB (Completed)

Trial results: (No results available)

EudraCT Number: 2008-006773-32

Sponsor Protocol Number: HPV_CSP01

Start Date*: 2009-05-20

Sponsor Name:Health Protection Agency

Full Title: A Phase IV, randomised study to evaluate the immune responses of UK adolescent girls receiving Cervarix(TM) or Gardasil(TM) Human Papillomavirus vaccines

Medical condition: This study will investigate vaccines that prevent premalignant cervical lesions and cervical cancer causally related to Human Papillomavirus (HPV) types 16 and 18. This study will investigate wheth...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10058580	Human papilloma virus serology test	LLT

Population Age: Adolescents, Under 18

Gender: Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2008-006652-22	Sponsor Protocol Number: AN08/8751	Start Date*: 2009-06-03
Sponsor Name:Leeds Teaching Hospital NHS Trust
Full Title: A multicentre, randomised, double blind, evaluative comparison trial of Rapydan® patch and Ametop® gel for topical anaesthesia during venous cannulation in adults admitted to hospital for day-case ...
Medical condition: ASA 1 and 2 patients admitted for Day case surgery- assessment of cannulation pain after topical anaesthetic applications.
Disease:
Population Age: Adults		Gender: Male, Female
Trial protocol: GB (Completed)
Trial results: View results

EudraCT Number: 2006-003327-36	Sponsor Protocol Number: ART1	Start Date*: 2007-01-08
Sponsor Name:Guy's & St Thomas' NHS Foundation Trust [...] 1. Guy's & St Thomas' NHS Foundation Trust 2. King's College London
Full Title: Evaluation of the efficacy of colchicine with and without betamethasone mouthwash in the management of recurrent aphthous stomatitis
Medical condition: Recurrent aphthous stomatitis (RAS)
Disease:
Population Age: Adults		Gender: Male, Female
Trial protocol: GB (Completed)
Trial results: View results

EudraCT Number: 2007-002653-23

Sponsor Protocol Number: 1/07

Start Date*: 2008-09-02

Sponsor Name:The Police Rehabilitation Centre, Flint House

Full Title: A pilot for a case control study to evaluate the effects of High Dosage Oxygen Therapy as an adjunct to an established program of physiotherapy and rehabilitation for sub acute soft tissue knee con...

Medical condition: Sub acute soft tissue injuries to the knee .

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10041292	Soft tissue injury NOS	LLT

Population Age: Adults

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: (No results available)

EudraCT Number: 2008-004534-24

Sponsor Protocol Number: 2007CV09

Start Date*: 2008-11-18

Sponsor Name:University of Dundee

Full Title: Can high-dose vitamin D supplementation reduce blood pressure and markers of cardiovascular risk in older people with isolated systolic hypertension?

Medical condition: Isolated systolic hypertension

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10050591	Isolated systolic hypertension	LLT

Population Age: Elderly

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2007-004897-26

Sponsor Protocol Number: Lu-11829A

Start Date*: 2008-05-23

Sponsor Name:King's College London [...]

Full Title: Memantine for the Long Term Management of Neuropsychiatric Symptoms in Alzheimer's disease - MAIN-AD

Medical condition: Alzheimer's disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10001896	Alzheimer's disease	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2008-005892-83	Sponsor Protocol Number: WCH/2008/001	Start Date*: 2009-01-14
Sponsor Name:Epsom and St Helier University Hospitals NHS Trust
Full Title: Does metformin improve pregnancy outcomes [ incidence of LGA (≥90% birth weight centile) babies onset of maternal Gestational Diabetes, hypertension, PET, shoulder dystocia, admission to SCBU) in o...
Medical condition: Obesity in pregnancy. Obesity in pregnancy has been identified by Confidential Enquiry into Maternal And Child Health (CEMACH) (2008-2011) as a major health risk to mother and baby.
Disease:
Population Age: Adults		Gender: Female
Trial protocol: GB (Completed)
Trial results: View results

EudraCT Number: 2008-005910-37

Sponsor Protocol Number: MEM 1414-101

Start Date*: 2009-02-27

Sponsor Name:Memory Pharmaceuticals Corp

Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Cross-Over Study to Evaluate the Efficacy, Safety and Tolerability of MEM 1414 (600 mg) on the Allergen-Induced Late Asthmatic Response ...

Medical condition: Mild Allergic Asthma

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10001705	Allergic asthma	LLT

Population Age: Adults

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: (No results available)

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The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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