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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44351   clinical trials with a EudraCT protocol, of which   7378   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    10,988 result(s) found. Displaying page 53 of 550.
    «« First « Previous 49  50  51  52  53  54  55  56  57  Next» Last»»
    EudraCT Number: 2006-004136-73 Sponsor Protocol Number: CTMK05 Start Date*: 2006-09-14
    Sponsor Name:Thornton & Ross Limited
    Full Title: A randomised, controlled, assessor-blind, clinical trial to demonstrate superiority of Hedrin 4% dimeticone lotion compared with Derbac-M 0.5% malathion aqueous liquid in the treatment of head lice
    Medical condition: Head louse infestation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10034214 Pediculus capitis (head louse) LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000262-20 Sponsor Protocol Number: DPOD III Start Date*: 2007-07-25
    Sponsor Name:Stanmore Clinical Research Facility Ltd
    Full Title: A phase III, 7 days randomised, double-blind, placebo-controlled, parallel group study to assess efficacy of DPZ for reducing the symptoms of post-operative delirium after an elective hip or knee r...
    Medical condition: Post-operative delirium.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012218 Delirium LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002202-30 Sponsor Protocol Number: R207910BAC2001 Start Date*: 2004-10-18
    Sponsor Name:Tibotec Pharmaceuticals Ltd.
    Full Title: An open label study to evaluate the effects on Mycobacterium tuberculosis, safety, tolerability and pharmacokinetics of single doses of R207910, in treatment naive patients with mycobacterium tuber...
    Medical condition: Tuberculosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-004541-34 Sponsor Protocol Number: 21092005 Start Date*: 2006-02-14
    Sponsor Name:South Manchester University Healthcare Trust
    Full Title: The Effect of Enteral Administration of Synbiotics Upon Infection Rates in Major Burns
    Medical condition: Major burn injuries: Thermal related trauma with burn injury involving significant proportions of the total body surface area, as defined by age: Adults (>=17 years old): >= 15% body surface area ...
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-003418-32 Sponsor Protocol Number: GS-US-104-0352 Start Date*: 2007-12-18
    Sponsor Name:Gilead Sciences Incorporated
    Full Title: A Phase III, Randomised, Open- Label Study Comparing the Safety and Efficacy of Switching Stavudine or Zidovudine to Tenofovir Disoproxil Fumarate versus Continuing Stavudine or Zidovudine in Virol...
    Medical condition: HIV-1 infected children (2 years to less than 12 years), who are virologically suppressed with HIV-1 RNA less than 400 copies/mL on their current antiretroviral regimen.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020192 HIV-1 LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2004-004231-53 Sponsor Protocol Number: 506067 Start Date*: 2004-12-22
    Sponsor Name:Royal Devon and Exeter NHS Foundation Trust
    Full Title: The Effect Of Antihypertensive Treatment With Lisinopril and Labetalol on Baroreflex Sensitivity in Stroke
    Medical condition: Stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004243-21 Sponsor Protocol Number: M200-1205 Start Date*: 2005-03-15
    Sponsor Name:PDL BioPharma, Inc.
    Full Title: Phase 2 Open-Label Study of Volociximab (M200) in Combination with Gemcitabine in Patients with Metastatic Pancreatic Cancer Not Previously Treated with Chemotherapy
    Medical condition: metastatic pancreatic cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004247-22 Sponsor Protocol Number: RES104033 Start Date*: 2005-06-07
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A 28-day, Randomised, Double-Blind, Active Comparator, Controlled Study to Assess the Effects of Rosiglitazone, Inhaled Corticosteroid, Theophylline and Theophylline Plus Inhaled Corticosteroid on ...
    Medical condition: Smokers that are asthmatic
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-004652-13 Sponsor Protocol Number: PSD502-PM-001 Start Date*: 2006-02-01
    Sponsor Name:PLETHORA SOLUTIONS LIMITED
    Full Title: Phase II, multi centre, randomised, double blind, placebo controlled, pilot study to determine efficacy, safety, tolerability and preliminary pharmacokinetics of PSD502 in the management of pain fr...
    Medical condition: management of pain from donor sites in burns subjects undergoing skin grafts
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-001386-42 Sponsor Protocol Number: REC no:06/Q0403/25 Start Date*: 2006-07-06
    Sponsor Name:Imperial College
    Full Title: The timing of intra-vitreal (4mg) triamcinolone acetonide, in addition to verteporfin photodynamic therapy for choroidal neovascularisation, in age-related macular degeneration: a prospective rando...
    Medical condition: Submacular choroidal neovascularisation in Age-related Macular Degeneration
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-000053-62 Sponsor Protocol Number: sph/itu/0001 Start Date*: 2007-06-18
    Sponsor Name:Ashford & St. Peter's Hospitals NHS Trust
    Full Title: The effects of helium-oxygen gas mixture (Heliox) on airway pressures in mechanically ventilated adult patients with acute lung injury
    Medical condition: Acute lung injury
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038696 Respiratory failure (excl neonatal) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-000497-23 Sponsor Protocol Number: 07/Q0703/18 Start Date*: 2007-05-02
    Sponsor Name:King's College Hospital NHS Foundation Trust [...]
    1. King's College Hospital NHS Foundation Trust
    2. King's College London
    Full Title: Do sulphponylureas preserve cortical function during hypoglycaemia in patients with type 1 diabetes and hypoglycaemia unawareness?
    Medical condition: We are testing the hypothesis that closing the K ATP channels using sulphonylureas (glibenclamide) during experimental insulin induced hypoglycaemia can help retain cerebral function and help enhan...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020997 Hypoglycaemia unawareness LLT
    9.1 10012608 Diabetes mellitus insulin-dependent LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-001982-41 Sponsor Protocol Number: RAE04 Start Date*: 2006-10-03
    Sponsor Name:Bradford Teaching Hospitals NHS Foundation Trust
    Full Title: An evaluation of the safety and effectiveness of combination therapy using the thiazolidinedione pioglitazone alongside insulin in type 2 diabetes mellitus.
    Medical condition: Type 2 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    8.1 10012601 Diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002208-32 Sponsor Protocol Number: PAR06 Start Date*: 2006-08-14
    Sponsor Name:York Hospital NHS Trust
    Full Title: A comparison of the analgesic efficacy of oral and intravenous paracetamol (perfalgan) in a day case setting
    Medical condition: We will perform a double blind randomised comparison of oral paracetamol versus intravenous paracetamol (Perfalgan) in patients undergoing knee arthroscopy in a day surgery setting.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-006761-32 Sponsor Protocol Number: A 091152 Start Date*: 2008-04-15
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: Vulval intraepithelial neoplasia: immune responses to human papillpmavirus.
    Medical condition: Vulval intraepithelial neoplasia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056574 Vulval intraepithelial neoplasia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2006-001571-37 Sponsor Protocol Number: AAV2/2-hRPE65p-hRPE65 Start Date*: 2006-12-14
    Sponsor Name:University College London
    Full Title: AN OPEN-LABEL DOSE ESCALATION STUDY OF AN ADENO-ASSOCIATED VIRUS VECTOR (AAV2/2-hRPE65p-hRPE65) FOR GENE THERAPY OF SEVERE EARLY-ONSET RETINAL DEGENERATION
    Medical condition: The condition to be investigated is severe early-onset inherited retinal degeneration due to defects in the gene encoding RPE65
    Disease: Version SOC Term Classification Code Term Level
    13.1 10015919 - Eye disorders 10038845 Retinal degeneration PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-010956-93 Sponsor Protocol Number: HM09/8885 Start Date*: 2009-09-17
    Sponsor Name:University of Leeds [...]
    1. University of Leeds
    2.
    Full Title: Randomised comparisons, in myeloma patients of all ages, of thalidomide, lenalidomide, carfilzomib and bortezomib induction combinations, and of lenalidomide and combination lenalidomide vorinostat...
    Medical condition: Newly diagnosed patients with symptomatic myeloma
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004864 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-008745-38 Sponsor Protocol Number: CKD-VitD-microcirc Start Date*: 2009-04-08
    Sponsor Name:Barts and the London NHS Trust
    Full Title: THE EFFECT OF VITAMIN D ON THE MICROCIRCULATION OF PATIENTS WITH CHRONIC KIDNEY DISEASE AND VITAMIN D DEFICIENCY
    Medical condition: Chronic kidney disease and vitamin D deficiency.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10047626 Vitamin D deficiency LLT
    9.1 10064848 Chronic kidney disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-006928-18 Sponsor Protocol Number: 06/Q0603/57 Start Date*: 2007-04-25
    Sponsor Name:Barts and The London NHS Trust
    Full Title: Randomised trial of Prontosan wound gel for prevention of exit site infection in peritoneal dialysis patients
    Medical condition: Peritoneal dialysis patients and their peritoneal dialysis catheter exit site care.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008831 Chronic ambulatory peritoneal dialysis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-013100-32 Sponsor Protocol Number: pms.nov.001 Start Date*: 2009-12-01
    Sponsor Name:University of Exeter [...]
    1. University of Exeter
    2. Royal Devon and Exeter NHS Foundation Trust
    Full Title: Does modulating the gut hormones, incretins, modify vascular function, thereby reducing the risk of vascular complications in insulin resistant individuals?
    Medical condition: Obese (BMI equal or greater than 30) individuals at a high risk of diabetes, but without overt cardiovascular disease or taking oral hypoglycaemic, anti-hypetensive or lipid lowering therapies. Pur...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029883 Obesity LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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