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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7380   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    26,035 result(s) found. Displaying page 1,248 of 1,302.
    EudraCT Number: 2007-003254-28 Sponsor Protocol Number: 782/07 Start Date*: 2008-03-15
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: RADIOCHEMIOTERAPIA CON TEMOZOLOMIDE CONCOMITANTE E ADIUVANTE NEL TRATTAMENTO DEI LINFOMI CEREBRALI PRIMITIVI DOPO METOTREXATE AD ALTE DOSI: STUDIO DI DOSE ESCALATION
    Medical condition: primary central nervous lymphoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025323 Lymphomas NEC HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-006794-93 Sponsor Protocol Number: 1788/07 Start Date*: 2008-09-02
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Randomized Evaluation of Intracoronary nitroprusside vs adenosine after thrombus aspiration during primary PErcutaneous coronary intervention for the prevention of No reflow in Acute Myocardial In...
    Medical condition: Acute myocardial infarction with ST segment elevation
    Disease: Version SOC Term Classification Code Term Level
    6.1 10000891 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-007799-40 Sponsor Protocol Number: 2021/07 Start Date*: 2008-01-28
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Evaluation of intralesional administration of rituximab for treatment of orbital lymphoma
    Medical condition: orbital lymphoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003899 B-cell lymphoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-004284-21 Sponsor Protocol Number: 987 Start Date*: 2007-07-06
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: A prospective randomized study of antibiotic prophylaxis for renal transplantation: short term vs standard treatment
    Medical condition: antibiotic prophylaxis for renal tranplantation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038533 Renal transplant LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000891-17 Sponsor Protocol Number: 221 Start Date*: 2010-03-26
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Biosensors in the exhaled breath analysis comparison between healthy and asthmatic children and effect of montelukast and fluticasone on frequency pattern detected by biosensors in children with ...
    Medical condition: asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-014670-17 Sponsor Protocol Number: CORPAD Start Date*: 2009-12-07
    Sponsor Name:H.-Hartziekenhuis Roeselare-Menen vzw
    Full Title: Controlled study on the Relative Pharmacokinetics of Advagraf versus Prograft in Kidney transplant patients with severe Diarrhoea
    Medical condition: Renal transplant patients suffering from diarrhea
    Disease: Version SOC Term Classification Code Term Level
    12.0 10038533 Renal transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003122-27 Sponsor Protocol Number: 767/11 Start Date*: 2011-11-01
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Assessment of aspirin response in patients with Type 1 diabetes mellitus: a pilot study
    Medical condition: type 1 diabetes
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10045228 Type I diabetes mellitus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004955-35 Sponsor Protocol Number: 1883/12 Start Date*: 2013-07-29
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: A single-center randomized double-blind placebo-controlled trial “Treatment of Systemic Sclerosis with Rituximab: evaluation of the effectiveness of B-cell depletion therapy”
    Medical condition: SYSTEMIC SCLEROSIS
    Disease: Version SOC Term Classification Code Term Level
    16.0 10028395 - Musculoskeletal and connective tissue disorders 10042953 Systemic sclerosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006445-18 Sponsor Protocol Number: 1403/08 Start Date*: 2010-09-23
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Paravertebral block: influence of Body Mass Index on the dosage of local anaesthetic.
    Medical condition: postoperative pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064882 Procedural pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014283-19 Sponsor Protocol Number: 575/09 Start Date*: 2009-08-04
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Effect of remifentanil on postoperative cognitive function in patients undergoing major abdominal surgery
    Medical condition: Elderly patients with risk of post operative cognitive dysfunction.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10009845 Cognitive disturbance LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-008285-12 Sponsor Protocol Number: 1655/08 Start Date*: 2009-10-14
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: PROSPECTIVE STUDY “IBDISC”: Regeneration and Immunity in patients affected by IBD undergoing immunomodulatory treatment and adjuvant role of G-CSF and/or plasmapheresis (Inflammatory Bowel Disease...
    Medical condition: Inflammatory bowel disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011401 PT
    9.1 10045282 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019421-33 Sponsor Protocol Number: 183/10 Start Date*: 2012-10-31
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Plasma sostitution in paediatric neurosurgery: comparison between two sinthetic colloids: HES 130/0,42/6:1 in normal salin solution (Voluven)vs HES 130/0,42/6:1 in balanced electrolitic solution (p...
    Medical condition: pediatric patients undergoing major neurosurgical procedures
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10029205 Nervous system disorders SOC
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-001060-21 Sponsor Protocol Number: 374/11 Start Date*: 2011-10-17
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Safety and efficacy of switching a stable combined antiretroviral therapeutic regimen to atazanavir with ritonavir plus lamivudine in treatment experienced HIV positive patients with full and stabl...
    Medical condition: HIV
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10008922 Chronic infection with HIV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-003773-41 Sponsor Protocol Number: 962/08 Start Date*: 2009-11-16
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Effect of heart rate and autonomic nervous system modulation on inflammatory state and peripheral vascular function in patients with type 2 diabetes.
    Medical condition: diabetes type 2
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001008-21 Sponsor Protocol Number: 2014/07 Start Date*: 2008-01-20
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Effect of leukotriene gene polymorphisms on response to montelukast, a leukotriene receptor antagonist, in adults with asthma
    Medical condition: asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-003649-10 Sponsor Protocol Number: 948/08 Start Date*: 2009-09-29
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Effect of hyperbaric or isobaric bupivacaine on spinal block and on cardiac function in elderly patients undergoing transurethral procedures
    Medical condition: spinal block and on cardiac function in elderly patients undergoing transurethral procedures
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002092 Anaesthesia and allied procedures HLT
    Population Age: Elderly Gender: Male
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000890-51 Sponsor Protocol Number: 200 Start Date*: 2007-03-13
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Biosensors in the exhaled breath analysis: comparison between healthy and asthmatic adults and effect of montelukast and fluticasone on frequency pattern detected by biosensors in adults with asthma
    Medical condition: asthma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005071-17 Sponsor Protocol Number: 15-50615 Start Date*: 2006-11-06
    Sponsor Name:Hormos Medical Ltd
    Full Title: Preliminary efficacy of OphenaTM (ospemifene) in the treatment of vasomotor symptoms associated with the menopause: a 6-week, randomized, double-blind, placebo-controlled, parallel-group study
    Medical condition: Postmenopausal symptoms (hot flashes)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10050903 Postmenopausal symptoms LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001561-32 Sponsor Protocol Number: UC-160/1204 Start Date*: 2012-09-11
    Sponsor Name:UNICANCER
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    15.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10001186 Adenocarcinoma of prostate LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-005165-11 Sponsor Protocol Number: GETUG 16/0504 Start Date*: 2006-06-16
    Sponsor Name:Fédération Nationale des Centres de Lutte Contre le Cancer
    Full Title: Etude randomisée multicentrique comparant l'efficacité d'une hormonothérapie courte par Zoladex® concomitante à une radiothérapie versus une radiothérapie exclusive dans le traitement de rattrapage...
    Medical condition: Avec 40 000 nouveaux cas par an en France, le cancer de la prostate est le second cancer pour l’ensemble de la population française et le premier chez l’homme. L'hormonothérapie est le traitement ...
    Disease: Version SOC Term Classification Code Term Level
    V.8 10060862 LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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