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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    26,035 result(s) found. Displaying page 1,248 of 1,302.
    «« First « Previous 1244  1245  1246  1247  1248  1249  1250  1251  1252  Next» Last»»
    EudraCT Number: 2012-005062-34 Sponsor Protocol Number: PhilosoPhi34 Start Date*: 2013-04-02
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE NIGUARDA CA' GRANDA (A.O. DI RILIEVO NAZIONALE)
    Full Title: An open label, single arm, phase II study of nilotinib 300 mg BID in newly diagnosed CP-CML patients, in order to verify disappearance of CD34+/lin-Ph+ cells from bone marrow during treatment.
    Medical condition: newly diagnosed CP-CML patients
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10052065 Chronic phase chronic myeloid leukaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002672-86 Sponsor Protocol Number: Altshock Start Date*: 2015-04-20
    Sponsor Name:AO OSPEDALE NIGUARDA CA' GRANDA
    Full Title: PHASE II CLINICAL TRIAL FOR A STEPWISE PROGRESSION IN THE TREATMENT OF CARDIOGENIC SHOCK
    Medical condition: Patients affected by cardiogenic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-020302-15 Sponsor Protocol Number: TOACT Start Date*: 2011-10-14
    Sponsor Name:IMM - Instituto de Medicina Molecular
    Full Title:
    Medical condition: Cerebral venous thrombosis
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029205 - Nervous system disorders 10008138 Cerebral venous thrombosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-003039-20 Sponsor Protocol Number: COMAN Start Date*: 2014-11-28
    Sponsor Name:A. O. Istituti Ospitalieri di Cremona
    Full Title: RANDOMIZED PHASE II STUDY WITH SEQUENTIAL NON-CROSS RESISTANT CHEMOTHERAPY IN PATIENTS WITH LOCALLY ADVANCED INOPERABLE OR METASTATIC GASTRO-ESOPHAGEAL ADENOCARCINOMA
    Medical condition: Locally advanced inoperable or metastatic gastro-esophageal adenocarcinoma
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10030144 Oesophageal adenocarcinoma stage III PT
    17.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10001150 Adenocarcinoma gastric PT
    17.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10030145 Oesophageal adenocarcinoma stage IV PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001103-21 Sponsor Protocol Number: ONC-MANILA12 Start Date*: 2012-12-05
    Sponsor Name:ISTITUTO NAZIONALE PER LA CURA TUMORI
    Full Title: MANTAINANCE METRONOMIC PER OS NAVELBINE IN ADVANCED NSCLC PATIENTS AFTER PREVIOUS PLATINUM BASED CHEMOTHERAPY: A MULTICENTER RANDOMIZED BEST SUPPORTIVE CARE CONTROLLED PHASE II STUDY: MA.NI.LA. TRIAL.
    Medical condition: Advanced non small cell lung cancer (NSCLC) (Inoperable Stage III - IV).
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029522 Non-small cell lung cancer stage IV PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029521 Non-small cell lung cancer stage IIIB PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003638-18 Sponsor Protocol Number: AG0112CR Start Date*: 2013-03-13
    Sponsor Name:Australasian Gastro-Intestinal Trials Group, Sydney University
    Full Title: Randomised Phase II study of cetuximab alone or in combination with irinotecan in patients with metastatic CRC with either KRAS WT or G13D mutation. ICE CREAM: The Irinotecan Cetuximab Evaluation a...
    Medical condition: metastatic colorectal cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) ES (Completed) IT (Completed) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005078-55 Sponsor Protocol Number: N01183 Start Date*: Information not available in EudraCT
    Sponsor Name:UCB PHARMA
    Full Title: Named Patient Program with Levetiracetam Oral Solution, for Pediatric Patients suffering from Epilepsy having previously participated in study N01148
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    6.1 10040703 PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004239-21 Sponsor Protocol Number: PAC325 Start Date*: 2012-12-03
    Sponsor Name:CTI BioPharma Corp.
    Full Title: A Randomized Controlled Phase 3 Study of Oral Pacritinib versus Best Available Therapy in Patients with Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemi...
    Medical condition: Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10028537 Myelofibrosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended) GB (Completed) CZ (Prematurely Ended) HU (Prematurely Ended) DE (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-001234-32 Sponsor Protocol Number: TOPMAT-MIG-3006 Start Date*: 2005-08-22
    Sponsor Name:Janssen Cilag International NV
    Full Title: A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Topiramate for the Prophylaxis of Migraine in Pediatric Subjects 12 to 17 Years of Age. Estudio aleatoriz...
    Medical condition: Migraine in Pediatric Population (12-17 year olds, inclusive)
    Disease:
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed) FI (Completed) NO (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2010-018342-31 Sponsor Protocol Number: ORAMORPH Start Date*: 2010-01-12
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA CAREGGI
    Full Title: PRE-EMPTIVE ANALGESIA E SURGICAL STRESS RESONSE WITH SUB-LINGUAL MORPHINE
    Medical condition: surgical patient
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10017947 Gastrointestinal disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004937-13 Sponsor Protocol Number: non previsto Start Date*: 2006-08-17
    Sponsor Name:Universita di Firenze
    Full Title: multicentee randomized controlled study of azathioprine versus iterferon beta in relapsing remitting multiple sclerosis
    Medical condition: patients with relapsing remitting multiple sclerosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028245 Multiple sclerosis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005028-10 Sponsor Protocol Number: FARM7PER7 Start Date*: 2008-10-14
    Sponsor Name:Universita' di Firenze; Dipartimento di Farmacologia Preclinica e Clinica
    Full Title: Methadone dose adjustments, plasma R-methadone levels and therapeutic outcome of opioid addiction
    Medical condition: Heroin dependence
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029205 Nervous system disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022835-13 Sponsor Protocol Number: WS776945 Start Date*: 2010-10-18
    Sponsor Name:UNIVERSITA` DEGLI STUDI DI FIRENZE - DIPARTIMENTO DI PSICOLOGIA
    Full Title: The Effects of Nicotine withdrawal on Panic-like Response to Breath Holding: A Placebo-Controlled, Double-Blind, Cross-Over Patch Study
    Medical condition: healthy current smokers
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009180 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004919-43 Sponsor Protocol Number: STOP-VD Start Date*: 2014-05-14
    Sponsor Name:SOD Medicina e Cardiologia Geriatrica, Centro per lo Studio della Sincope - Università degli Studi di Firenze-AOUCareggi
    Full Title: Suspension of vasoactive drugs in reflex vasodepressive syncope: a randomized controlled trial
    Medical condition: Vasodepressive neuroreflex syncope
    Disease: Version SOC Term Classification Code Term Level
    16.1 10029205 - Nervous system disorders 10042777 Syncope vasovagal LLT
    16.1 10029205 - Nervous system disorders 10042772 Syncope PT
    16.1 10029205 - Nervous system disorders 10067550 Neurally mediated syncope LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012575-10 Sponsor Protocol Number: CH/2007/2661 Start Date*: 2009-11-16
    Sponsor Name:University Hospitals Bristol NHS Foundation Trust [...]
    1. University Hospitals Bristol NHS Foundation Trust
    2. University of Liverpool
    Full Title: Trial of Optimal Therapy for Pseudomonas Eradication in Cystic Fibrosis
    Medical condition:
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Prematurely Ended) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004284-36 Sponsor Protocol Number: IT01 Start Date*: Information not available in EudraCT
    Sponsor Name:AOU CAREGGI
    Full Title: A Prospective, Randomized, Multi-Center, Pilot Study of Osigraft on distraction osteogenesis : OSIGRAFT VS STANDARD TREATMENT
    Medical condition: Treatment in distraction osteogenesis on tibial diaphysis osteotomy site because of previous resection for non-union, infection, trauma, or for reasons not linked to resection (i.e. aesthetics)of a...
    Disease: Version SOC Term Classification Code Term Level
    6.1 10028395 SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-004823-11 Sponsor Protocol Number: remifentanil2011 Start Date*: 2012-08-03
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA CAREGGI
    Full Title: Randomized prospective multicenter study on remifentanil analgesic efficacy in labor: intermittent intravenous infusion administration vs continuous intravenous infusion
    Medical condition: women during labor
    Disease: Version SOC Term Classification Code Term Level
    15.0 10036585 - Pregnancy, puerperium and perinatal conditions 10029772 Normal pregnancy, labour and delivery HLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003036-31 Sponsor Protocol Number: 01B Start Date*: 2012-03-20
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA CAREGGI
    Full Title: Ministry of health integrated oncological program n°5/2006: 18F-Fluorometilcholine (18FFCH) PET/CT sensibility in diagnosis of breast cancer metastasis
    Medical condition: de novo breast cancer metastasis
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10055113 Breast cancer metastatic PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-004545-18 Sponsor Protocol Number: NA Start Date*: 2005-04-26
    Sponsor Name:CHU Sart Tilman
    Full Title: Cell therapy for cardiac repair through mobilization of hematopoietic stem cells and endothelial progenitors in patients with chronic ischemic cardiomyopathy.
    Medical condition: Chronic ischemic cardiac disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005210-20 Sponsor Protocol Number: 2005-005210-20 Start Date*: 2006-04-10
    Sponsor Name:CHU Sart-Tilman
    Full Title: Phase II trial of caspofungin as secondary prophylaxis for invasive fungal infections in patients with high-risk hematological malignancies undergoing intensive chemotherapy or hematopoietic stem ...
    Medical condition: Acute leukemia during induction or consolidation therapy. Autologous HSCT for a hematological malignancy. Standard allogeneic HSCT with a myeloablative conditioning regimen.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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