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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44343   clinical trials with a EudraCT protocol, of which   7372   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    26,035 result(s) found. Displaying page 229 of 1,302.
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    EudraCT Number: 2007-002614-19 Sponsor Protocol Number: FluvalAB-H-YL2007 Start Date*: 2007-09-05
    Sponsor Name:Omninvest Ltd.
    Full Title: FluvalAB Seasonal Influenza Vaccine Serologic Clinical Trial for 2007-2008 Influenza Season
    Medical condition: Immunization of healthy people against influenza virus infections.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2004-004620-12 Sponsor Protocol Number: dyspnoea1 Start Date*: 2005-01-14
    Sponsor Name:Royal Marsden Hospital
    Full Title: Assessment of normal release morphine in the management of dyspnoea
    Medical condition: Breathlessness of any cause in cancer patients are identified and treated with normal release morphine which has been shown to be both effective and safe.The idea of the trial is to see if there wi...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-001305-42 Sponsor Protocol Number: CSPP100A2405 Start Date*: 2008-05-29
    Sponsor Name:Novartis Pharma Services AG
    Full Title: An eight-week double-blind, multi-center, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of aliskiren 75mg, 150mg and 300mg in elderly patients with essent...
    Medical condition: hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) IS (Completed) FR (Completed) NL (Completed) CZ (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-001325-34 Sponsor Protocol Number: 17/2008/U/Sper Start Date*: 2008-04-01
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: PROMISE AMI (PROtection of coronary Microcirculation by Iloprost: Safety and Efficacy evaluation in Acute Myocardial Infarction treated by primary PCI) Pilot Study
    Medical condition: Acute myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064346 STEMI LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-000709-12 Sponsor Protocol Number: C19562/2037/BC/EU Start Date*: 2008-05-27
    Sponsor Name:Cephalon France
    Full Title: Prospective, Open-Label, Randomized Study of Combination Therapy of MYOCET® Plus Cyclophosphamide and Trastuzumab Versus Free Doxorubicin Plus Cyclophosphamide Alone, Each Followed by Docetaxel and...
    Medical condition: Patients with human epidermal growth factor receptor-2 (HER2) positive stage II or III breast cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065430 HER-2 positive breast cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: FR (Completed) BE (Completed) ES (Completed) AT (Completed) NL (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-003708-77 Sponsor Protocol Number: 6096A1-3006_B1851007 Start Date*: 2012-03-07
    Sponsor Name:Pfizer Inc., 235 East 42nd Street, New York, NY 10017
    Full Title: A Phase 3, Randomized, Active-Controlled, Double-Blind Trial Evaluating the Impact of a 13-Valent Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization With Vaccine Serotypes of Streptococc...
    Medical condition: Prevention of invasive disease, pneumonia and acute otitis media caused by Streptococcus pneumoniae in infants and children from 6 weeks to 5 years of age.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10061353 Pneumococcal infection PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2008-003731-20 Sponsor Protocol Number: HODIVA Start Date*: 2008-10-21
    Sponsor Name:Karolinska Universitetssjukhuset
    Full Title: Postoperative Hyperbaric Oxygen treatments to reduce complications in Diabetic patients undergoing Vascular Surgery (HODIVA) - A double blind, randomized controlled study
    Medical condition: Postoperative complications after vascular surgery in the leg. This includes wound infections, wound dehiscience and necrosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057480 Hyperbaric oxygen therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003732-38 Sponsor Protocol Number: M/100977/21 Start Date*: 2009-09-03
    Sponsor Name:Laboratorios Almirall, S.A.
    Full Title: A PHASE IIa, RANDOMISED, DOUBLE-BLIND, MULTIPLE DOSE, PLACEBO CONTROLLED, 3 PERIOD CROSS-OVER, ASCENDING DOSE CLINICAL TRIAL TO ASSESS THE EFFICACY, SAFETY, TOLERABILITY AND PHARMACOKINETICS OF THR...
    Medical condition: Adult male subjects, aged 18 to 70 years, clinically diagnosed of persistent asthma (according to GINA guidelies 2007 update) for at least 6 months before screening, but who are otherwise in good g...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-003369-42 Sponsor Protocol Number: ET2007-035 Start Date*: 2007-10-19
    Sponsor Name:CENTRE LEON BERARD
    Full Title: Etude de phase II randomisée, multicentrique, en ouvert, évaluant l'efficacité de l’association Avastin (bevacizumab) + Torisel (temsirolimus) versus Sutent (sunitinib) versus Avastin+ Roféron(inte...
    Medical condition: Patient en 1ère ligne de traitement d'un cancer du rein métastique.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050076 Metastatic renal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-001692-30 Sponsor Protocol Number: 003/07 Start Date*: 2009-11-06
    Sponsor Name:Certmedica International GmbH
    Full Title: monocentric randomised double-blind pilot trial, double dummy design for comparison of two therapy reginem formoline L112 vs. Orlistat 60 mg in patients with overweight or adipositas
    Medical condition: The product alli and the comparsion product fromoline L112 (medical device) decrease weight by influencing the fat absorption. The effects of both regimes should cause similar results in weight loss.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001718-26 Sponsor Protocol Number: DFI10560 Start Date*: 2010-05-07
    Sponsor Name:Sanofi-Aventis Recherche & Développement
    Full Title: An eight-week, multicenter, randomized, double-blind, placebo-controlled dose-finding study, with escitalopram (10mg daily) as active control, to evaluate the efficacy, safety and tolerability of t...
    Medical condition: Major Depressive Disorder
    Disease: Version SOC Term Classification Code Term Level
    11.0 10025453 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed)
    Trial results: View results
    EudraCT Number: 2007-004737-42 Sponsor Protocol Number: AGO/2007/009 Start Date*: 2007-10-11
    Sponsor Name:University Hospital Ghent
    Full Title: Moviprep versus fleet phospho-soda (golden standard): een vergelijkende studie van laxativa als voorbereiding van de darm op een chirurgische ingreep
    Medical condition: Preoperatieve darmreiniging
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-007013-20 Sponsor Protocol Number: MK-0683-080 (P2135) Start Date*: 2007-02-23
    Sponsor Name:Onkologisk afdeling R and the Unit for Experimental Chemotherapy
    Full Title: A Phase I/II non-comparative Study of Paclitaxel plus Carboplatin in combination with Vorinostat in patients with advanced, recurrent epithelial ovarian cancer
    Medical condition: Advanced, recurrent epithelial ovarian cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033160 Ovarian epithelial cancer recurrent LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-007019-25 Sponsor Protocol Number: Delusional Parasitosis 1/Dec 2006 Start Date*: 2008-01-21
    Sponsor Name:Barts and the London NHS Trust
    Full Title: Pilot open trial of efficacy of Risperidone in Delusional Parasitosis
    Medical condition: Delusional Parasitosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012242 Delusion of parasitosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-000177-22 Sponsor Protocol Number: TRI 50c-01/02/001 Start Date*: 2004-12-02
    Sponsor Name:TRIGEN
    Full Title: An open-label, multi-centre, Phase IIa study to evaluate the safety, tolerability, pharmacodynamic efficacy and dose-related pharmacokinetics of titrated doses of the intravenous thrombin inhibitor...
    Medical condition: Chronic renal failure in patients undergoing chronic haemodialysis.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10018367 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001889-33 Sponsor Protocol Number: 1790 Start Date*: 2007-08-24
    Sponsor Name:North Bristol NHS Trust
    Full Title: Does an 8 week course of Ambulatory Oxygen Increase Diffuse Parenchymal Lung Diseases Patients Ability to Perform a 6 Minute Walk Test and/or Improve Patients Perception of Quality of Life as measu...
    Medical condition: Patients enrolled will have a diagnosis of restrictive lung disease diagnosed by a High Resolution CT scan, reduced gas transfer result (obtained from pulmonary function tests) and low lung volumes...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033318 Oxygen saturation decreased LLT
    9.1 10050322 Oxygen supplementation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002881-20 Sponsor Protocol Number: HGG-2006 Start Date*: 2006-08-17
    Sponsor Name:University Hospital Gasthuisberg
    Full Title: HGG-2006: a phase I/II clinical trial for the treatment of newly diagnosed high grade glioma with tumor vaccination as "add-on therapy" to standard primary treatment
    Medical condition: Adults with newly diagnosed glioblastoma multiforme
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-002887-25 Sponsor Protocol Number: 2601 Start Date*: 2006-06-27
    Sponsor Name:GOIM GRUPPO ONCOLOGICO MERIDIONALE
    Full Title: Bevacizumab+folfiri in untreated patients with advanced colorectal cancer. A phase II multicenter study of the Gruppo Oncologico dell'Italia Meridionale. (GOIM).
    Medical condition: untreated patients with advanced colorectal cancer.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010035 Colorectal cancer stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004580-19 Sponsor Protocol Number: REVIR Start Date*: 2008-10-14
    Sponsor Name:CHU DE POITIERS
    Full Title: PHARMACOKINETICS, SAFETY AND EFFICACY OF LENALIDOMIDE (REVLIMID®) IN COMBINATION WITH DEXAMETHASONE IN PATIENTS WITH MULTIPLE MYELOMA AND IMPAIRED RENAL FONCTION
    Medical condition: multiple myeloma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004587-38 Sponsor Protocol Number: M10-467 Start Date*: 2009-06-03
    Sponsor Name:Abbott GmbH & Co. KG
    Full Title: A Phase 2 Multicenter Study of the Safety and Efficacy of Adalimumab in Subjects with Moderate to Severe Chronic Hidradenitis Suppurativa
    Medical condition: Hidradenitis Suppurativa (HS) is a painful, chronic, skin disease characterized by recurrent inflamed nodules, abscesses, and fistulas, which may heal with scarring. The most commonly involved ana...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020041 Hidradenitis suppurativa LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) NL (Completed) DK (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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