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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,339 result(s) found. Displaying page 1,080 of 2,217.
    EudraCT Number: 2008-007763-16 Sponsor Protocol Number: 1.0 Start Date*: 2009-05-06
    Sponsor Name:Medizinische Universität Wien, Univ.Klinik f.Frauenheilkunde,Abt. f.Gynäkologie und Gyn.Onkologie
    Full Title: Topical Imiquimod in Treating Patients with Grade 2/3 Cervical Intraepithelial Neoplasia
    Medical condition: Grade 2/3 Cervical Intraepithelial Neoplasia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049701 Cervical intraepithelial neoplasia II LLT
    9.1 10049702 Cervical intraepithelial neoplasia III LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-002024-28 Sponsor Protocol Number: 0-001-FR Start Date*: 2008-03-18
    Sponsor Name:POLICLINICO SAN DONATO IRCSS
    Full Title: QUIXIL VALIDATION IN HIP REPLACEMENT FIRST IMPLANT
    Medical condition: Hip arthitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031173 Osteoarthropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-000397-71 Sponsor Protocol Number: kepp3 Start Date*: 2006-05-16
    Sponsor Name:Søren H. Sindrup, Department of Neurology, Odense University Hospital
    Full Title: Double-blind, randomised, placebo-controlled trial of levetiracetam for central neuropathic pain in patients with multiple sclerosis
    Medical condition:
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-011505-16 Sponsor Protocol Number: 3.0 Start Date*: 2010-01-21
    Sponsor Name:Medizinische Universität Wien,KIM I,Klinische Abteilung für Infektionen u.Tropenmedizin
    Full Title: Pharmacokinetics of intraperitoneal and intravenous fosfomycin in automated peritoneal dialysis patients without peritonitis
    Medical condition: A total of 8 patients with renal insufficiency and treatment with automated peritoneal dialysis (APD) will be enrolled into this study evaluating the pharmacokinetics of fosfomycin in this special ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10034660 Peritoneal dialysis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-016532-12 Sponsor Protocol Number: Version1.0 Start Date*: 2009-12-28
    Sponsor Name:Medical University of Vienna
    Full Title: Target tissue concentration of standard antibiotic treatment in coronary artery bypass grafting using left internal mammary artery
    Medical condition: antibiotic target tissue protection during cardiac surgery with the use of an internal mammary artery graft to prevent deep sternal wound infection
    Disease: Version SOC Term Classification Code Term Level
    12.0 10011078 Coronary artery disease LLT
    12.0 10036894 Prophylactic antibiotic therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-019343-20 Sponsor Protocol Number: 654-002 Start Date*: 2010-10-15
    Sponsor Name:LOTUS PHARMACEUTICAL CO., LTD.
    Full Title: A DOUBLE-BLIND, RANDOMISED, PARALLEL-GROUP STUDY TO COMPARE THE SAFETY AND EFFICACY OF TWO DOSE LEVELS OF OMS210 WITH PLACEBO IN THE TREATMENT OF PATIENTS WITH DIARRHOEA PREDOMINANT IRRITABLE BOWEL...
    Medical condition: Diarrhoea predominant irritable bowel syndrome
    Disease: Version SOC Term Classification Code Term Level
    12.1 10048571 Irritable bowel syndrome aggravated LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) BE (Completed) CZ (Completed) DE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-000399-81 Sponsor Protocol Number: APZ2-II-01 Start Date*: 2016-03-29
    Sponsor Name:RHEACELL GmbH & Co. KG
    Full Title: AN INTERVENTIONAL, SINGLE ARM, PHASE I/IIA CLINICAL TRIAL TO INVESTIGATE THE EFFICACY AND SAFETY OF APZ2 ON WOUND HEALING OF CHRONIC VENOUS ULCER (CVU)
    Medical condition: Chronic venous ulcers (CVU)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10066677 Chronic leg ulcer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-013642-80 Sponsor Protocol Number: TCAPGB Start Date*: 2009-09-30
    Sponsor Name:Department of Neurology, Odense University Hospital
    Full Title: Randomised, double-blind, placebo-controlled trial of the effect of the combination of imipramine and pregabalin for the treatment of painful polyneuropathy
    Medical condition: Painful polyneuropathy (idiopathic, diabetic, alcoholic, drug-induced and other etiologies)
    Disease: Version SOC Term Classification Code Term Level
    12.0 10036105 Polyneuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-002452-87 Sponsor Protocol Number: P-Monofer-IBD-03 Start Date*: 2017-09-11
    Sponsor Name:Pharmacosmos A/S
    Full Title: A randomized, double-blinded, comparative trial comparing the incidence of hypophosphatemia in relation to repeated treatment courses of iron isomaltoside and ferric carboxymaltose in subjects with...
    Medical condition: Iron deficiency anemia in subject with inflammatory bowel disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10005329 - Blood and lymphatic system disorders 10005329 Blood and lymphatic system disorders SOC
    20.0 10005329 - Blood and lymphatic system disorders 10079322 Anaemia of chronic inflammation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended) GB (Prematurely Ended) AT (Prematurely Ended) SE (Prematurely Ended) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-000966-23 Sponsor Protocol Number: BCG_influenza Start Date*: 2014-05-30
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: The effects of BCG-vaccination on the immune response induced by influenza-vaccination in healthy volunteers A pilot proof-of-principle study
    Medical condition: Influenza virus infection
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004862 10022005 Influenza viral infections HLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-021868-15 Sponsor Protocol Number: 9785-CL-0222 Start Date*: 2011-07-25
    Sponsor Name:Astellas Pharma Global Development, Inc. (APGD)
    Full Title: A Randomized, Double-Blind, Phase II, Efficacy and Safety Study of MDV3100 (ASP9785) vs. Bicalutamide in Castrate Men with Metastatic Prostate Cancer
    Medical condition: Metastatic Prostate Cancer
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10036909 Prostate cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed) BE (Completed) DE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-002831-16 Sponsor Protocol Number: TUD-TEMANX-065 Start Date*: 2015-10-20
    Sponsor Name:Technische Universität Dresden
    Full Title: Validation of a test system for development of medications for alcoholism
    Medical condition: male and female volunteers aged 25-55 years with moderate risky alcohol consumption of at least 41 g/day (men) or 31 g/day (women), according to European Medicines Agency (EMA, 2010) this is at lea...
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004869 10049180 Alcohol product use HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-009056-20 Sponsor Protocol Number: 1.0 Start Date*: 2010-01-21
    Sponsor Name:MUW, Department of Clinical Pharmacology
    Full Title: Does staphylothrombin enhance coagulation activation in staphylococcus aureus bacteremia?
    Medical condition: Patients with staphylococci bacteremia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054637 Staphylococcal bacteremia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-020042-94 Sponsor Protocol Number: LS07-040 Start Date*: 2010-09-02
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin
    Full Title: The Effect of High-dose Remifentanil on the Reversal of Neuropathic Pain in Postherpetic Patients
    Medical condition: Post herpetic hyperalgesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-000379-18 Sponsor Protocol Number: 1.0 Start Date*: 2012-05-04
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Klinische Pharmakologie
    Full Title: Plasma and synovial fluid pharmacokinetics of cefuroxime and linezolid in patients undergoing elective knee arthroscopy after a single intravenous dose of cefuroxime and linezolid: an exploratory m...
    Medical condition: Subjects under general anaesthesia after a knee surgery get a microdialysis probe insertio into the operated knee and a probe insertion into the thigh on the contralateral side. After the operation...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-012713-22 Sponsor Protocol Number: version 28.10.2009 Start Date*: 2010-05-06
    Sponsor Name:Medizinische Universität Wien, Univ. Klinik für Anästhesie, Allg. Intensivmedizin u Schmerztherapie
    Full Title: Randomized Double-blind Study Comparing the Efficacy of Duloxetine with Placebo in Patients with Chronic Low Back Pain
    Medical condition: efficacy of duloxetine in the treatment of patients with chronic low back pain to placebo
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004344-30 Sponsor Protocol Number: Moli1901-010A Start Date*: 2005-10-31
    Sponsor Name:AOP Orphan Pharmaceuticals AG
    Full Title: An Evaluation of the Safety and Tolerability of Multiple Dose Regimens of Aerosolized Moli1901 in Adolescents (12 Years of Age or Older) and Adults with Cystic Fibrosis and Stable Lung Disease
    Medical condition: Cystic fibrosis is the most common fatal inherited disease in the Caucasian population, affecting about 4 in 10,000 children. In cystic fibrosis chloride transport across the respiratory epithelium...
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: AT (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2007-000498-42 Sponsor Protocol Number: PB-06-001 Start Date*: 2008-05-08
    Sponsor Name:Protalix Biotherapeutics
    Full Title: A Phase III Multicenter, Randomized, Double-Blind Trial to Assess the Safety and Efficacy of Two Parallel Dose Groups of Plant Cell Expressed Recombinant Human Glucocerebrosidase (prGCD) in Patient...
    Medical condition: Gaucher disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018048 Gaucher's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) IT (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-005684-26 Sponsor Protocol Number: Version_1_10072006 Start Date*: 2007-09-06
    Sponsor Name:Universitätsklinik für Augenheilkunde und Optometrie, AKH Wien
    Full Title: Identification and Quantification of Cytokines in Anti-VEGF Therapy and Genetic Risk Factors in Exsudative Age-related Macular Degeneration
    Medical condition: Exsudative age-related macular degeneration (AMD), cataract, macular pucker
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015902 Exudative senile macular degeneration of retina LLT
    9.1 10007739 Cataract LLT
    9.1 10025417 Macular puckering of retina LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004540-31 Sponsor Protocol Number: Theophyllin_2 Start Date*: Information not available in EudraCT
    Sponsor Name:Universitätsklinikum Tübingen
    Full Title: Monozentrische, randomisierte, placebo-kontrollierte Studie zur Evaluation der Nephroprotektion durch Theophyllin unter Cisplatin-haltiger Chemotherapie
    Medical condition: evaluation of the nephroprotective efficacy of oral theophylline in patients treated with cisplatin
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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