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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44399   clinical trials with a EudraCT protocol, of which   7411   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,399 result(s) found. Displaying page 185 of 2,220.
    EudraCT Number: 2006-001977-17 Sponsor Protocol Number: CVAA489ADE02 Start Date*: 2006-10-17
    Sponsor Name:Novartis Pharma GmbH
    Full Title: An open-label, randomized, parallel group study comparing the efficacy and safety of Amlodipine in combination with Valsartan compared to Losartan in combination with Hydrochlorothiazide given for ...
    Medical condition: patients with mild-to-moderate hypertension and left ventricular hypertrophy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10049773 Left ventricular hypertrophy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001979-38 Sponsor Protocol Number: MultiH/BRA/711 (incl. Amendment #2) Start Date*: 2007-01-15
    Sponsor Name:Bracco Imaging Deutschland GmbH
    Full Title: INTRAINDIVIDUAL CROSS-OVER STUDY TO COMPARE MULTIHANCE® AND OMNISCAN® AT A DOSE OF 0.1 MMOL/KGBW IN THE DIFFERENTIAL DIAGNOSIS OF DISC HERNIATION VS. SCAR
    Medical condition: Intervertebral disc herniation
    Disease: Version SOC Term Classification Code Term Level
    8.1 10048856 Intervertebral disc herniation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-001791-36 Sponsor Protocol Number: 310781 Start Date*: 2008-01-24
    Sponsor Name:Bayer Schering Pharma AG
    Full Title: A double-blind, randomized, placebo and active controlled, multicenter study to investigate efficacy and safety after oral administration of 2 and 3 mg ZK 283197, 1 mg 17ß-estradiol and placebo onc...
    Medical condition: Vasomotor symptoms (hot flushes)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed) NL (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-001794-28 Sponsor Protocol Number: 806 Start Date*: 2007-10-15
    Sponsor Name:OrbusNeich Medical BV
    Full Title: Endothelial Function following stenting with Genous vs Drug-Eluting Stents
    Medical condition: Patients with symptomatic ischemic heart disease expressing one or two de novo native coronary artery lesions
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011078 Coronary artery disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001817-40 Sponsor Protocol Number: NAF 3.4.05.003 Start Date*: 2007-05-10
    Sponsor Name:Netherlands Asthma Foundation (NAF) [...]
    1. Netherlands Asthma Foundation (NAF)
    2. Stichting astma bestrijding
    Full Title: An early diagnosis of asthma in young children by using non-invasive biomarkers of oxidative stress/airway inflammation
    Medical condition: young children with recurrent respiratory symptoms
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001826-28 Sponsor Protocol Number: BL-2007-02 Start Date*: 2007-11-28
    Sponsor Name:Queen Mary University London
    Full Title: A phase II/III, randomised, two-arm comparison of maintenance lapatinib versus placebo after firrst-line chemotherapy in patients with HER1 and/or HER2 over expressing locally advanced or metastati...
    Medical condition: The medical condition being investigated in this trial is locally advanced or metastatic urological cancer. The tumour must overexpress HER1 and/or HER2 gene.
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10005012 Bladder cancer stage IV PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-001828-12 Sponsor Protocol Number: 110221 Start Date*: 2007-05-07
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A Phase III, open, non-randomized, multi-centric, single dose study to assess immunogenicity and safety of Fluarix™ (Influsplit SSW®) 2007/2008 injected intramuscularly in young adults (18 to 60 ye...
    Medical condition: Immunization against influenza of healthy adults
    Disease: Version SOC Term Classification Code Term Level
    9.1 10016794 Flu vaccination LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-005025-11 Sponsor Protocol Number: BAY43-9006/13162 Start Date*: 2009-05-06
    Sponsor Name:Bayer Healthcare AG, D-51368 Leverkusen, Germany
    Full Title: A Phase 2b, Double Blind, Randomized Study Evaluating the Efficacy and Safety of Sorafenib Compared With Placebo When Administered in Combination With Chemotherapy (Modified FOLFOX6) for the Treatm...
    Medical condition: The patient population includes patients with Stage IV metastatic colorectal cancer (mCRC), with Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1. Patients must have measurable ...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000418-20 Sponsor Protocol Number: D1450C00001 Start Date*: 2006-04-06
    Sponsor Name:AstraZeneca AB
    Full Title: A 4-week randomized, double-blind, placebo controlled, parallel group, phase II study to assess the efficacy and safety of gefitinib tablets, 250 mg once daily (OD), in adult patients with moderate...
    Medical condition: Moderate Chronic Obstructive Pulmonary Disease (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended) FI (Prematurely Ended) NO (Prematurely Ended) SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-002216-10 Sponsor Protocol Number: 2006012 Start Date*: 2006-11-27
    Sponsor Name:Procter & Gamble Pharmaceuticals
    Full Title: A Multicenter, Double-blind, Randomized, Parallel, Placebo-controlled Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of 2 Oral Doses, 25 mg Twice Daily and 100 mg Twice Daily, of PG 7...
    Medical condition: Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) HU (Completed) NL (Completed) GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002286-32 Sponsor Protocol Number: 6125 Start Date*: 2009-08-10
    Sponsor Name:Queen Mary Medical University of London
    Full Title: Phase I/II Study combining humanised anti-CD20 (veltuzumab), anti-CD22 (epratuzumab) and both monoclonal antibodies with chemotherapy in adults with recurrent B precursor acute lymphoblastic leukae...
    Medical condition: This is a phase I/ II trial to determine the efficacy of intravenous veltuzumab and epratuzmab either individually or together in combination with chemotherapy in patients with recurrent acute lymp...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003890 B precursor type acute leukaemia LLT
    9.1 10003917 B-cell type acute leukaemia LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002292-27 Sponsor Protocol Number: NonOnco2008 Start Date*: 2008-06-23
    Sponsor Name:OSPEDALE POLICLINICO S. MATTEO
    Full Title: Long term opioid administration in no-oncologic chronic pain: open label, prospective study on efficacy, safety and pharmacokinetic factors
    Medical condition: chronic pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-002314-21 Sponsor Protocol Number: MEN IFR/08/NEB-HYP/01 Start Date*: 2008-05-23
    Sponsor Name:A. MENARINI I.F.R.
    Full Title: VALUTAZIONE COMPARATIVA DEGLI EFFETTI SULLA FUNZIONE ENDOTELIALE DEL TRATTAMENTO CON NEBIVOLOLO E IDROCLOROTIAZIDE VS IRBESARTAN E IDROCLOROTIAZIDE IN PAZIENTI CON IPERTENSIONE ARTERIOSA NEO-DIAGNO...
    Medical condition: IPERTENSIONE ARTERIOSA
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    9.1 10047065 Vascular disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-005637-11 Sponsor Protocol Number: BV-2007/06 Start Date*: 2008-08-04
    Sponsor Name:OM Pharma SA
    Full Title: Efficacy of Broncho-Vaxom in elderly patients with chronic bronchitis; a double-blind, randomised, placebo-controlled study
    Medical condition: Chronic bronchitis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10008841 Chronic bronchitis LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005639-26 Sponsor Protocol Number: EFC10528 Start Date*: 2008-04-21
    Sponsor Name:Oxford BioMedica
    Full Title: A Multicenter, Double Blind, Placebo controlled, Randomized study of TroVax vs Placebo in the First Line treatment of Patients with Metastatic Colorectal Cancer receiving Chemo-based Therapy.
    Medical condition: Metastatic Colorectal Adenocarcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) ES (Prematurely Ended) DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-005916-15 Sponsor Protocol Number: MC-UK.3/AVK Start Date*: 2008-04-25
    Sponsor Name:medac Gesellschaft für klinische Spezialpräparate mbH
    Full Title: Low dose Urokinase therapy by patients with diabetic foot syndrom and critical limb ischemia versus conventionel standard therapy. A randomised, open, controlled Phase III-study.
    Medical condition: Patients with angiopathic or angioaneuropathic diabetic foot syndrome and critical limb ischemia without the possibility of surgical or interventional revascularisation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012664 Diabetic foot ulcer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-005922-62 Sponsor Protocol Number: OXN2501 Start Date*: 2008-05-22
    Sponsor Name:Mundipharma Research GmbH & Co. KG
    Full Title: An exploratory, randomised, active-controlled, double-blind, double-dummy, parallel group pilot study to determine the ability of oxycodone/naloxone prolonged release tablets (OXN) to reduce the nu...
    Medical condition: Opioid induced constipation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021175 Iatrogenic constipation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) HU (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-006790-81 Sponsor Protocol Number: APREC S2007-01 Start Date*: 2008-07-28
    Sponsor Name:APREC
    Full Title: Phase II study of pegylated liposomal doxorubicin (Caelyxâ) in breast cancer patients with brain metastases and not candidate for an antiHER2 therapy
    Medical condition: Breast Cancer Patients with Brain Metastases
    Disease: Version SOC Term Classification Code Term Level
    9.1 10055113 Breast cancer metastatic PT
    9.1 10027475 Metastatic breast cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-006795-10 Sponsor Protocol Number: FPH-Macugen08 Start Date*: 2008-08-15
    Sponsor Name:Frimley Park Hospital NHS Foundation Trust
    Full Title: A randomised controlled trial of efficacy of Pegaptanib sodium in the prevention of proliferative diabetic retinopathy
    Medical condition: Diabetic Retinopathy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054109 Non-proliferative diabetic retinopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-001579-40 Sponsor Protocol Number: P04440 Start Date*: 2007-04-02
    Sponsor Name:Schering-Plough France
    Full Title: Study of peripheral enthesitis with ultrasonography doppler in spondyloarthropathies treated with infliximab
    Medical condition: Spondyloarthropathies
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002556 Ankylosing spondylitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended) ES (Completed) DK (Prematurely Ended) HU (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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