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Clinical trials for HIV

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44394   clinical trials with a EudraCT protocol, of which   7406   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,466 result(s) found for: HIV. Displaying page 2 of 74.
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    EudraCT Number: 2022-001591-33 Sponsor Protocol Number: DoRSwitch.21 Start Date*: 2022-10-06
    Sponsor Name:Fundació Clinic per a la Recerca Biomèdica
    Full Title: Open-label, single-arm, unicenter and Pilot Study of a Switch strategy from Etravirine (ETR) to Doravirine (DOR) in Virologically-Suppressed HIV-1 Infected Adults With ETR-Resistance
    Medical condition: Human Immunodeficiency Virus (HIV)
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10020161 HIV infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-003186-28 Sponsor Protocol Number: BPC01_002 Start Date*: 2016-01-13
    Sponsor Name:Bionor Pharma ASA
    Full Title: BIOSKILL: Studying Vacc-4x, an HIV therapeutic vaccine, an assessment of immune-mediated anti-viral effects, when administered with adjuvant GM-CSF prior to HIV latent reservoir activation by the H...
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    19.0 10021881 - Infections and infestations 10020161 HIV infection PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002661-30 Sponsor Protocol Number: HLS/MVC01/2008 Start Date*: 2008-06-13
    Sponsor Name:AZIENDA OSPEDALIERA L. SACCO (A.O. DI RILIEVO NAZIONALE)
    Full Title: Use of Maraviroc (MVC) in immunogical non-responder HIV-1-infected patients.
    Medical condition: HIV-1-infected HAART-treated patients that reached a virologic suppression without a reconstitution of their immune system.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006716-30 Sponsor Protocol Number: 128/2006/O/Sper Start Date*: 2006-12-19
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Randomized, controlled, multicentric trial to evaluate efficacy and safety of the switch from a LPV/r based therapy to an ATV/r or a NVP based treatment in association with ABC/3TC, in HIV patient ...
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10020161 HIV infection PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-000793-45 Sponsor Protocol Number: TMC114-C209 Start Date*: Information not available in EudraCT
    Sponsor Name:Tibotec Pharmaceuticals Ltd.
    Full Title: Open-label safety study of TMC114 in combination with low dose RTV and other ARVs in highly experienced HIV-1 infected patients with limited or no treatment options.
    Medical condition: HIV-1 infected patient
    Disease: Version SOC Term Classification Code Term Level
    7.1 10020161 4
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-011273-32 Sponsor Protocol Number: 149/09 Start Date*: 2009-05-07
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Pilot study for the evaluation of the safety and the feasibility of treatment simplification to atazanavir/ritonavir + lamivudine in patients on stable treatment with two NRTIs + atazanavir/ritonav...
    Medical condition: HIV
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020443 Human immunodeficiency virus syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001164-32 Sponsor Protocol Number: KISS Start Date*: 2005-04-05
    Sponsor Name:AZIENDA OSPEDALIERA "OSPEDALI RIUNITI DI BERGAMO" (A.O. DI RILIEVO NAZIONALE)
    Full Title: A RANDOMIZED STUDY, POSPECTIVE, ON THREE DIFFERENT STRATEGY OF HIV POSITIVE NAIVE FOR THE ANTIRETROVIRAL THERAPY
    Medical condition: HIV INFECTION CHRONIC AND NAIVE. VIREMIE > 10.000 COPIE/ML AND/OR CD4< 350 CELL/01
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014216-35 Sponsor Protocol Number: PG001 Start Date*: 2009-10-20
    Sponsor Name:AZIENDA SANITARIA LOCALE 4 DI TORINO
    Full Title: REYAGEN study. Optimization of unboosted atazanavir dosing, when associated with tenofovir, guided by pharmacogenetics profile of HIV-patients
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005405-21 Sponsor Protocol Number: UMCN-AKF 07.06 Start Date*: 2008-01-21
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: The influence of Raltegravir (MK_0518) on the pharmacokinetics of single-dose Lamotrigine in healthy male subjects (GRANOLA)
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2004-000336-81 Sponsor Protocol Number: APV102027 Start Date*: 2004-07-08
    Sponsor Name:GLAXO SMITHKLINE
    Full Title: GW433908 Expanded Access Program for HIV infected subjects non responding or intolerant to the previous antiretroviral treatments
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    6.1 10020161 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-023316-13 Sponsor Protocol Number: 1384/10 Start Date*: 2011-05-23
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Randomized multicenter study on security and efficacy of therapeutic switch to maraviroc + darunavir/ritonavir once daily in patients who are in triple antiretroviral regimen with three drugs belo...
    Medical condition: Infection of HIV
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005330-37 Sponsor Protocol Number: HLS01/2007 Start Date*: 2008-02-20
    Sponsor Name:AZIENDA OSPEDALIERA L. SACCO (A.O. DI RILIEVO NAZIONALE)
    Full Title: Pharmacokinetics of atazanavir at the dose of 300mg or 400mg in subjects with HIV-1 infection and non-decompensated hepatic cirrhosis (Child-Pugh A o B, Metavir F4), crossover study.
    Medical condition: HIV-1 Infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-007200-16 Sponsor Protocol Number: ISS T-002 Start Date*: 2008-06-13
    Sponsor Name:ISTITUTO SUPERIORE DI SANITA'
    Full Title: A Phase II randomized, open label, immunogenicity and safety trial of the vaccine based on the recombinant biologically active HIV-1 Tat protein in anti-Tat negative HIV-1 infected HAART-treated ad...
    Medical condition: HIV-1 infected subjects
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004936-34 Sponsor Protocol Number: Atazanavir Start Date*: 2005-06-22
    Sponsor Name:AZIENDA OSPEDALIERA POLICLINICO DI MODENA
    Full Title: Il therapeutic drug monitoring di Atazanavir in pazienti con infezione da HIV e malattia epatica terminale valutati per trapianto ortotopico di fegato
    Medical condition: Insufficienza epatica terminale con infezione HIV
    Disease: Version SOC Term Classification Code Term Level
    6.1 10000807 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000526-48 Sponsor Protocol Number: A.S.T.R.A. Start Date*: 2007-03-06
    Sponsor Name:AZIENDA OSPEDALIERA POLICLINICO DI MODENA
    Full Title: Randomized, monocentric trial on sintoms, adherence,toxicity of alternate antiretrovirale regimen
    Medical condition: PT HIV-1 positive and naive to antiretroviral drug
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006212-30 Sponsor Protocol Number: IMIRC1002 Start Date*: 2007-08-09
    Sponsor Name:Imperial College London
    Full Title: A Randomised, Open labelled, Phase II, Immunogenicity, and Exploratory Efficacy Evaluation of Therapeutic Immunisations +/- IL-2, GM-CSF and Growth Hormone in HIV-1 Infected Subjects Receiving High...
    Medical condition: HIV-1
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-002460-98 Sponsor Protocol Number: VS411-C201 Start Date*: 2008-02-07
    Sponsor Name:VIROSTATICS, SRL
    Full Title: A randomized double-blind dose-finding multi-centre phase IIa study with VS411 for HIV-1 infection.
    Medical condition: HIV-1 infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012543-42 Sponsor Protocol Number: DIS-MVC Start Date*: 2010-01-21
    Sponsor Name:Fundació Clínic
    Full Title: Efecto del maraviroc (MVC) en la recuperación inmunológica de pacientes infectados por el VIH-1 con respuesta discordante y una cifra de linfocitos CD4 inferior a las 200 células/mm3
    Medical condition: Pacientes con infección por VIH
    Disease: Version SOC Term Classification Code Term Level
    9 10020172 HIV infection NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007018-12 Sponsor Protocol Number: QUINAVIR Start Date*: 2008-06-23
    Sponsor Name:Carlos Alonso-Villaverde Lozano, Hospital Universitari Sant Joan de Reus
    Full Title: “Estudio prospectivo, abierto, aleatorizado y cruzado sobre el efecto de la Hidroxicloroquina, 200mg al día, en factores inflamatorios y metabólicos relacionados con la enfermedad cardiovascular en...
    Medical condition: Infección por el virus de la inmunodeficiencia adquirida
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020160 HIV disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002978-35 Sponsor Protocol Number: HLS05/2008 Start Date*: 2008-07-24
    Sponsor Name:AZIENDA OSPEDALIERA L. SACCO (A.O. DI RILIEVO NAZIONALE)
    Full Title: Intensification of HAART with Maraviroc (MVC) as first line therapy of HIV-1-infected patients to rapidly suppress viral replication and minimize the evolution of drug-resistant variants
    Medical condition: First line therapy of HIV-1-infected patients.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020441 Human immunodeficiency virus infection, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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