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Clinical trials for Imaging

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    4,216 result(s) found for: Imaging. Displaying page 2 of 211.
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    EudraCT Number: 2006-004153-22 Sponsor Protocol Number: 310788 Start Date*: 2007-04-18
    Sponsor Name:Bayer Schering Pharma AG
    Full Title: Open-label multi-center study of magnetic resonance imaging (MRI) with 0.1 mmol/kg BW Gadovist (1.0 M) to assess pharmacokinetics, safety and tolerability in children
    Medical condition: Gadovist as diagnostic imaging agent is approved only for adult patients. Diseases usually representing indications for contrast-enhanced Magnetic Resonance Imaging (CE-MRI) are common also in a pe...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029815 Nuclear magnetic resonance imaging PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed) SE (Completed) DK (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2004-004701-23 Sponsor Protocol Number: 2104-03 Start Date*: 2005-03-14
    Sponsor Name:Epix Pharmaceuticals, Inc.
    Full Title: Phase II feasibility study to evaluate the safety and efficacy of EP-2104R for Magnetic Resonance Imaging of thrombi in the arterial vasculature and cardiac chambers
    Medical condition: Detection of thrombi in the arterial vasculature and cardiac chambers
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-000070-29 Sponsor Protocol Number: 74668 Start Date*: 2022-09-15
    Sponsor Name:VU University Medical Center
    Full Title: A Proof-of-Concept Study to Explore the Potential Efficacy of Deferiprone in Patients With Pelizaeus-Merzbacher disease (PMD)
    Medical condition: Pelizaeus-Merzbacher disease
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-004415-24 Sponsor Protocol Number: 09/2011MolecularImaging Start Date*: 2012-01-16
    Sponsor Name:IRCCS CENTRO SAN GIOVANNI DI DIO
    Full Title: Molecular imaging for the early diagnosis and monitoring of Alzheimer’s disease in old individuals with cognitive disturbances: an ADNI-compatible prospective study
    Medical condition: Mild Congitive Impairment (MCI)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10050727 RI scan LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-003825-31 Sponsor Protocol Number: GDX-44-015 Start Date*: 2022-02-28
    Sponsor Name:Guerbet
    Full Title: Gadopiclenol Pharmacokinetics, Safety and Efficacy in Pediatric Patients < 2 Years of Age Undergoing Contrast-enhanced MRI P/0145/2019
    Medical condition: Known or highly suspected abnormalities/ lesion(s) as detected by previous imaging examinations (including the fetal imaging) that need to be investigated by contrast-enhanced MRI of any body regio...
    Disease: Version SOC Term Classification Code Term Level
    22.1 100000004848 10029815 Nuclear magnetic resonance imaging LLT
    22.1 100000004848 10058644 Nuclear magnetic resonance imaging whole body LLT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) PL (Prematurely Ended) BG (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-000551-41 Sponsor Protocol Number: IMPACT_Breast_6.3 Start Date*: 2014-03-18
    Sponsor Name:University Medical Center Groningen
    Full Title: Towards patient tailored cancer treatment supported by molecular imaging IMPACT: IMaging PAtients for Cancer drug selecTion – Metastatic Breast Cancer
    Medical condition: Metastatic Breast Cancer
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003669-24 Sponsor Protocol Number: NET-2011-02346784 Start Date*: 2017-01-30
    Sponsor Name:OSPEDALE SAN RAFFAELE
    Full Title: Amyloid PET imaging study for the diagnosis of Alzheimer's disease in the preclinical/predementia phase
    Medical condition: memory complaint, mild cognitive impairment, Alzheimer's Disease in predrmentia/prodromal disease phases
    Disease: Version SOC Term Classification Code Term Level
    22.1 100000004848 10050727 RI scan LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004244-35 Sponsor Protocol Number: 1/25-03-2014 Start Date*: 2015-03-05
    Sponsor Name:IRCCS Ospedale San Raffaele
    Full Title: AMYLOID LOAD IN PRODROMAL AD WITH LIMBIC-PREDOMINANT PHENOTYPE PRINCIPAL INVESTIGATOR - STUDIO DEL CARICO DI AMILOIDE IN AD PRODROMICO CON FENOTIPO LIMBICO
    Medical condition: mild cognitive impairment, Alzheimer's disease prodromal
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004848 10050727 RI scan LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003089-29 Sponsor Protocol Number: 69918356615 Start Date*: 2018-04-06
    Sponsor Name:Medical University of Vienna, Department of Biomedical Imaging and Image-guided Therapy
    Full Title: Measuring hallmarks of cancer for non-invasive characterization of breast lesions by simultaneous multiparametric 18F-ethylcholine PET- MRI – an exploratory study
    Medical condition: Patients with imaging suspected breast cancer (BI-RADS 4&5 on conventional imaging, e.g. mammography and ultrasound).
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006291 Breast neoplasms malignant and unspecified (incl nipple) HLGT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006288 Breast neoplasms benign (incl nipple) HLGT
    20.0 10022891 - Investigations 10029815 Nuclear magnetic resonance imaging PT
    20.0 10022891 - Investigations 10036223 Positron emission tomography LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001619-37 Sponsor Protocol Number: 48895 Start Date*: 2014-07-14
    Sponsor Name:Maastricht University Medical Centre
    Full Title: Contrast enhanced Diffusion-weighted Magnetic Resonance Imaging for detection of pathologic lymph nodes in ovarian cancer – a feasibility study.
    Medical condition: Ovarian Cancer - diagnosis of lymph nodes
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-003512-37 Sponsor Protocol Number: OC-AP-ICG-IV-2 Start Date*: 2014-10-13
    Sponsor Name:Jules Bordet Institute
    Full Title: Study of the (intravenously injected) ICG (Indocyanine Green) imaging of tumoral implants in patients with peritoneal carcinomatosis from colorectal origin.
    Medical condition: Imaging of tumours and their metastasis after intravenous injection of Indocyanine Green to patients with peritoneal carcinomatosis from colorectal cancer.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004217-14 Sponsor Protocol Number: P21.128 Start Date*: 2022-11-09
    Sponsor Name:Leiden University Medical Center
    Full Title: FLUOPANC-trial - Intraoperative near-infrared fluorescence imaging in pancreatic- and extrahepatic bile duct tumors using cRGD-ZW800-1 and dedicated imaging systems: A phase II feasibility, dose-ra...
    Medical condition: Pancreatic cancer (pancreatic carcinoma) Extrahepatic bile duct cancer (cholangiocarcinoma)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003522-86 Sponsor Protocol Number: P18.210 Start Date*: 2019-03-21
    Sponsor Name:Leiden University Medical Center
    Full Title: Imaging tumor angiogenesis using 18F-Fluciclatide PET/CT in patients with colorectal and pancreatic cancer.
    Medical condition: Patient suffering from colorectal or pancreatic adenocarcinoma.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-000184-78 Sponsor Protocol Number: 2020110470 Start Date*: 2021-06-21
    Sponsor Name:Odense University Hospital
    Full Title: Recurrent and Metastatic Prostate Cancer: Impact of 18F-PSMA-1007 PET/CT on clinical decision making and response monitoring
    Medical condition: Metastatic Prostate Cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10076506 Castration-resistant prostate cancer LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-000690-78 Sponsor Protocol Number: 19773 Start Date*: 2018-10-29
    Sponsor Name:Bayer AG
    Full Title: LowEr Administered Dose with highEr Relaxivity: Gadovist vs Dotarem
    Medical condition: Contrast enhancement in magnetic resonance imaging (MRI) for central nervous system (CNS), magnetic resonance (MR) angiography, liver, kidney and other body regions
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004848 10028049 MRI LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-006724-35 Sponsor Protocol Number: fMRI-CA_2008 Start Date*: 2008-09-08
    Sponsor Name:CMIV
    Full Title: Functional MRI after administration of Gd-based blood pool contrast agents
    Medical condition: This study aims to investigate the possibility to obtain higher functional contrast and better spatial assessment in contrast enhanced functional Magnetic Resonance Imaging (fMRI) as compared to st...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029820 Nuclear magnetic resonance imaging gadolinium-enhanced LLT
    9.1 10029817 Nuclear magnetic resonance imaging brain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001552-36 Sponsor Protocol Number: 18SEIN08 Start Date*: 2020-09-09
    Sponsor Name:INSTITUT CLAUDIUS REGAUD
    Full Title: The use of FES-PET imaging as a tool to detect a possible reversion of Estrogen Receptor (ER)-α status in patients with metastatic breast cancer HER2 + and ERα neg treated with trastuzumab + pertuz...
    Medical condition: Metastatic breast cancer HER2 + and ERα neg.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10027475 Metastatic breast cancer LLT
    Population Age: Adults Gender: Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-002751-19 Sponsor Protocol Number: 82160 Start Date*: 2023-04-11
    Sponsor Name:Amsterdam UMC
    Full Title: FAPi-PET imaging of in vivo fibrosis in inflammatory bowel disease patients
    Medical condition: Inflammatory Bowel Diseases
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-002804-19 Sponsor Protocol Number: 10975 Start Date*: 2023-06-21
    Sponsor Name:University Medical Center Groningen
    Full Title: Improving radical resection rates in patients with breast cancer by intraoperative imaging using bevacizumab-IRDye800CW – the MARGIN-2 study
    Medical condition: Female breast cancer patients with small tumor size in which breast conserving therapy is advised by the multidisciplinary tumor board.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003268-19 Sponsor Protocol Number: BR-TUM-ICG-IV-2 Start Date*: 2014-10-06
    Sponsor Name:Jules Bordet Institute
    Full Title: Study evaluating breast cancer tumorectomy guided by Near-Infrared imaging after the intravenous injection of free Indocyanine Green
    Medical condition: Imaging of tumours and their margins after intravenous injection of Indocyanine Green to breast cancer patients
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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