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Clinical trials for Side effects

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    2,084 result(s) found for: Side effects. Displaying page 2 of 105.
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    EudraCT Number: 2014-004962-76 Sponsor Protocol Number: Solenne-OxoF-Rosa Start Date*: 2015-01-27
    Sponsor Name:Solenne BV
    Full Title: The treatment of Rosacea with Oxofulleram. A pilot study to assess the clinical applicability of Oxofulleram
    Medical condition: papulopustular rosacea
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002730-36 Sponsor Protocol Number: CaEP68962 Start Date*: 2019-11-14
    Sponsor Name:Department of Dermatology, Bispebjerg Hospital
    Full Title: Calcium electroporation for basal cell carcinomas – a ’Proof of concept’ study
    Medical condition: Basal cell carcinomas
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10042503 Superficial basal cell carcinoma LLT
    21.1 100000004864 10073093 Nodular basal cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-007019-10 Sponsor Protocol Number: AGO/2007/015 Start Date*: 2008-01-21
    Sponsor Name:University Hospital Ghent
    Full Title: Comparison of the therapeutic efficacy and side effects of tramadol per os (Tradonal Odis® orodispersible tablets) versus an optimised dosis of travenous tramadol for postoperative pain relief in a...
    Medical condition: Ambulatory surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005451-42 Sponsor Protocol Number: DISCAP Start Date*: 2009-01-13
    Sponsor Name:University Medical Center Groningen
    Full Title: Long-term use of antipsychotics for behavioral symptoms in patients with mental retardation; a controlled discontinuation study
    Medical condition: Mental retardation
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2014-000760-18 Sponsor Protocol Number: 13.034 Start Date*: 2014-11-24
    Sponsor Name:Prof. Peter Licht
    Full Title: Supplementary Epidural Analgesia in Video-Assisted Thoracic Surgery (VATS) - The SEAVATS Study.
    Medical condition: Cancer pulmones
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-000882-22 Sponsor Protocol Number: KARISMAII Start Date*: 2016-07-11
    Sponsor Name:Karolinska Institute
    Full Title: Karisma II: A randomized, double blinded, six-armed placebo controlled study to imnvestigate optimal dose of tamoxifen with the most favourable side effect spectra and with density reduction non-in...
    Medical condition: The mammographic density reduction in healthy women, within the Karma cohort for five different doses of tamoxifen.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2020-005633-33 Sponsor Protocol Number: 202000842 Start Date*: 2021-06-02
    Sponsor Name:University Medical Center Groningen
    Full Title: Prediction of ECT treatment response and reduction of Cognitive Side-effects using EEG and Rivastigmine
    Medical condition: A depressive disorder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-003061-25 Sponsor Protocol Number: MPEEG_2 Start Date*: 2016-12-14
    Sponsor Name:Department of Neurology, Christian Doppler Medical Center, Paracelsus Medical University Salzburg
    Full Title: Pharmaco-EEG for Montelukast. Can we detect neural changes during medication with Montelukast in the EEG?
    Medical condition: Montelukast is indicated for prophylaxis and chronic treatment of asthma and for the relief of symptoms of seasonal allergic rhinitis. We investigate side effects of Montelukast, specifically poten...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-013022-16 Sponsor Protocol Number: ZonMw 80-82100-98-096/11510014 Start Date*: 2009-10-21
    Sponsor Name:Erasmus MC [...]
    1. Erasmus MC
    2. ZonMw
    Full Title: Effecten en bijwerkingen van opioïden: een studie naar de rol van farmacokinetische en farmacogenetische heterogeniteit.
    Medical condition: Nociceptive cancer pain for which strong opioids are needed
    Disease: Version SOC Term Classification Code Term Level
    9.1 10058019 Cancer pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003693-17 Sponsor Protocol Number: KetKet_2008 Start Date*: 2008-09-10
    Sponsor Name:Leiden University Medical Center
    Full Title: Treatment of Complex Regional Pain Syndrome type I: A randomised, double-blind, placebo-controlled study with multiple rounds of S(+)-ketamine infusions
    Medical condition: Chronic CRPS ian
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001221-98 Sponsor Protocol Number: 1.3 Start Date*: 2018-06-25
    Sponsor Name:Medical University of Vienna, Department of Clinical Pharmacology
    Full Title: DEXAMETHASONE AS ADJUVANT FOR PERIPHERAL NERVE BLOCKADE: A RANDOMIZED, TRIPLE-BLINDED AND CROSSOVER STUDY IN VOLUNTEERS
    Medical condition: The combination of local anaesthetics plus dexamethasone shall increase the duration of regional anaesthetic blocks. It is a volunteers´study. Three different block combination are performed. One b...
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-001700-23 Sponsor Protocol Number: ketapop08 Start Date*: 2008-09-26
    Sponsor Name:None
    Full Title: Finding best practice: use of s-ketamine peroperatively and in patient controlled analgesia in the treatment of pain after major abdominal surgery.
    Medical condition: Patient between 18 and 70 years old undergoing major abdominal surgery through a midline incision.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001167-22 Sponsor Protocol Number: 43488 Start Date*: 2017-06-29
    Sponsor Name:
    Full Title: Spinal Morphine in laparoscopic gastro-intestinal surgery
    Medical condition: Patients with indications for laparoscopic gastro-intestinal surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004799-11 Sponsor Protocol Number: 2006OB01 Start Date*: 2007-11-29
    Sponsor Name:Coombe Women's Hospital
    Full Title: A randomised trial of oxytocin bolus versus oxytocin bolus and infusion for the control of blood loss at elective caesarean section.
    Medical condition: Elective lower segment caesarean section
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004053-26 Sponsor Protocol Number: SEEG 0001 Start Date*: 2005-04-14
    Sponsor Name:Birthe Pedersen
    Full Title: An explorative use open-label, multi-center, randomized trial studying the safety and efficacy of levetiracetam (500 mg/day to 3000 mg/day) and valproate (600 mg/day to 3000 mg/day) as monotherapy ...
    Medical condition: Newly diagnosed epilepsy patients are over 65 years. In this age group more cases are symptomatic and it is apparently another disorder than epilepsy in adults. Epilepsy in the elderly is easier to...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-003216-37 Sponsor Protocol Number: n.a. Start Date*: 2015-02-12
    Sponsor Name:
    Full Title: Efficacy of Verapamil/ Verapamil-Kenacort injection versus Kenacort injection in Scar Treatment
    Medical condition: Hypertrophic and keloid scars are pathological scars as a result of dermal injury and exhibit exuberant, indefinite growth of collagen during wound healing. Hypertrophic and keloid scars often caus...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-005087-14 Sponsor Protocol Number: CPP-401 Start Date*: 2008-11-12
    Sponsor Name:Centre Paul Papin
    Full Title: Comparison of 2 morphine administration’s mode using Pump IntraThecal (IDDS)for Analgesia in patients with Cancer pain, resistant to conventional antalgic treatment
    Medical condition: Patients with intractable cancer pain, either uncontrolled with standard analgesia , or undergoing severe side effects due to analgesia . Patients undergo implantation of a Medtronic intrathecal pu...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10058019 Cancer pain LLT
    9.1 10059050 Intractable pain LLT
    Population Age: Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018878-21 Sponsor Protocol Number: SSAT036 Start Date*: 2010-08-16
    Sponsor Name:St Stephen's AIDS Trust
    Full Title: A phase III, open-label, single centre, single-arm, pilot study to assess the feasibility of switching, individuals receiving efavirenz with continuing Central Nervous System (CNS) toxicity, to ral...
    Medical condition: HIV
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000925-30 Sponsor Protocol Number: 10 Start Date*: 2013-05-04
    Sponsor Name:Uppsala University
    Full Title: How common are mood and sexual side-effects from combined oral contraceptives?
    Medical condition: Healthy women
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10030970 Oral contraception PT
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000789-19 Sponsor Protocol Number: MiniCept Start Date*: 2007-05-30
    Sponsor Name:CHU de Liège, Domaine Universitaire du Sart Tilman
    Full Title: Withdrawal of Calcineurin Inhibitors (CNIs) during administration of Mycophenolate Mofetil (MMF) in liver transplant patients suffering adverse effects from CNIs: Study of the reduction in rejectio...
    Medical condition: liver transplant patients suffering adverse effects from treatment with calcineurin inhibitors
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050434 Prophylaxis against liver transplant rejection LLT
    9.1 10054980 Immunosuppressant drug therapy LLT
    9.1 10052538 Adverse drug reaction NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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