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Clinical trials for Placebo comparator

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,805 result(s) found for: Placebo comparator. Displaying page 21 of 91.
    EudraCT Number: 2007-002223-32 Sponsor Protocol Number: E2007-0507 Start Date*: Information not available in EudraCT
    Sponsor Name:Charité Universitaetsmedizin
    Full Title: A multicentre, double-blind, randomised placebo-controlled trial of sodium bicarbonate to prevent acute kidney injury in patients undergoing cardiopulmonary bypass surgery.
    Medical condition: Cardiac surgical patients in whom the use of cardiopulmonary bypass is planned and having at least one ore more of the following risk factors for post-operative acute kidney injury • Age ≥ 70 years...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-000626-35 Sponsor Protocol Number: D5670C00004 Start Date*: 2017-08-07
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase IIb, Randomised, Parallel, Double-Blind Placebo-Controlled and Open-Label Active Comparator Study to Evaluate the Efficacy and Safety of MEDI0382 in the Treatment of Overweight and Obese Su...
    Medical condition: Type 2 diabetes mellitus (T2DM)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) SK (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2011-002326-49 Sponsor Protocol Number: I1F-MC-RHAP Start Date*: 2013-11-05
    Sponsor Name:Eli Lilly & Company
    Full Title: A Multicenter, Randomized, Double-Blind, Active and Placebo-Controlled 24-Week Study Followed by Long-Term Evaluation of Efficacy and Safety of Ixekizumab (LY2439821) in Biologic Disease-Modifying ...
    Medical condition: Arthritic Psoriasis
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004859 10037160 Psoriatic arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) GB (Completed) BE (Completed) EE (Completed) BG (Completed) ES (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2007-002417-39 Sponsor Protocol Number: ONO-5334POE003 Start Date*: 2007-08-31
    Sponsor Name:Ono Pharmaceutical Co., Ltd.
    Full Title: A MULTI-CENTRE RANDOMISED DOUBLE BLIND, PLACEBO AND ACTIVE CONTROLLED PARALLEL GROUP STUDY TO INVESTIGATE EFFICACY AND SAFETY OF ONO-5334 IN POST MENOPAUSAL WOMEN WITH OSTEOPENIA OR OSTEOPOROSIS
    Medical condition: Osteoporosis or Osteopenia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049088 Osteopenia LLT
    9.1 10031285 Osteoporosis postmenopausal LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed) LT (Completed) HU (Completed) NL (Completed) EE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2016-003331-38 Sponsor Protocol Number: I1F-MC-RHCD Start Date*: Information not available in EudraCT
    Sponsor Name:Eli Lilly and Company
    Full Title: Multicenter, Double-Blind, Randomized, Active- and Placebo Controlled Study to Evaluate Safety, Tolerability, and Efficacy of Ixekizumab in Patients from 6 to Less than 18 Years of Age with Moderat...
    Medical condition: Moderate-to-Severe Plaque Psoriasis
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004858 10071117 Plaque psoriasis LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed) DE (Completed) ES (Completed) PL (Completed) HU (Completed) CZ (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2004-000211-26 Sponsor Protocol Number: D5890L00007 Start Date*: 2004-08-04
    Sponsor Name:AstraZeneca AB
    Full Title: A comperative, placebo-controlled, doubleblind, double dummy, cross over, single center phase IIIb study between formoterol alone and the fixed combination of formoterol and budesonide on airway re...
    Medical condition: Patient with stable and mild allergic asthma.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2004-001999-40 Sponsor Protocol Number: EGF30001 Start Date*: 2004-11-25
    Sponsor Name:GlaxoSmithKline R&D Ltd
    Full Title: A randomised, multicentre, double-blind, placebo-controlled, 2-arm, Phase III study of oral GW572016 in combination with paclitaxel in subjects previously untreated for advanced or metastatic breas...
    Medical condition: Advanced or metastatic breast cancer
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-000359-16 Sponsor Protocol Number: VD-3 Start Date*: 2007-04-16
    Sponsor Name:Ove Bäck, Dept Dermatology, University Hospital, Lund, Sweden
    Full Title: Vitamin D and atopic allergy
    Medical condition: Cumulative incidence of atopic allergy specified as atopic dermatitis, allergic asthma, and allergic rhinitis. Since IMP is a food supplement to protect from rickets we are looking at clinical sym...
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004752-13 Sponsor Protocol Number: MAR-LEV-2005-01 Start Date*: 2006-05-25
    Sponsor Name:H. Universitari Germans Trias i Pujol
    Full Title: Comparación cruzada, a doble ciego, aleatoria, de dosis única, de levocetirizina con desloratadina, rupatadina, ebastina y placebo: supresión de la respuesta de pápula y eritema inducida por histam...
    Medical condition: Rinitis alérgica estacional
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005382-19 Sponsor Protocol Number: AARCOPDHP03 Start Date*: 2007-06-22
    Sponsor Name:University Hospitals of Leicester NHS Trust
    Full Title: Helicobacter eradication therapy in Chronic Obstructive Pulmonary Disease: A pilot,randomised, double blinded, placebo controlled trial
    Medical condition: Chronic Obstructive Airways Disease: Defined as a consistent clinical picture with evidence of airflow obstruction (FEV1 < 70%, FEV1/FVC Ratio <70%, with no evidence of reversibility in FEV1 after ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-004524-21 Sponsor Protocol Number: 9000 Start Date*: 2008-02-12
    Sponsor Name:Medicinsk gastroenterologisk afdeling, Aalborg Sygehus S
    Full Title: Undersøgelse af opioiders analgetiske og anti-hyperalgesiske effekt på eksperimentelle smertemodeller i huden, musklerne og knoglerne
    Medical condition: Eksperimentelle smertemodeller
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001027-59 Sponsor Protocol Number: NEO-040 Start Date*: 2008-10-21
    Sponsor Name:University of Dundee
    Full Title: A Randomised, Double-Blind, Double-Dummy Cross-Over Study to demonstrate Superiority of Fluticasone/ Salmeterol pMDI over double the dose of Fluticasone pMDI on Methacholine Hyper-Reactivity in Pat...
    Medical condition: Asthma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-005494-22 Sponsor Protocol Number: Start Date*: 2012-06-21
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: GaPP: A pilot randomised controlled trial of the efficacy and mechanism of action of gabapentin for the management of chronic pelvic pain in women
    Medical condition: Chronic pelvic pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004872 10048581 Pelvic pain female LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-000284-14 Sponsor Protocol Number: Start Date*: 2016-01-05
    Sponsor Name:University of Calgary
    Full Title: Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects
    Medical condition: Vasovagal Syncope
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-001231-29 Sponsor Protocol Number: 2005-01-02 Start Date*: 2005-09-08
    Sponsor Name:Dept of Transplantation Surgery B 56, Karolinska University Hospital, Huddinge
    Full Title: A PROSPECTIVE, RANDOMISED, PLACEBO CONTROLLED, MULTI-CENTER STUDY OF THE EFFICACY AND SAFETY OF RITUXIMAB AS INDUCTION THERAPY TOGETHER WITH TACROLIMUS, MYCOPHENOLATE MOFETIL AND STEROIDS FOR PATI...
    Medical condition: Chronic renal failure patients who are receiving a kidney transplant. Different immunosuppressive protocls are awailable. However, current strategies for the medical management of transplant patie...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001960-28 Sponsor Protocol Number: RCTVITD/SARS-CoV-19 Start Date*: 2020-05-25
    Sponsor Name:Investigation Institute Bioaraba
    Full Title: Efficacy of vitamin D treatment in patients diagnosed with pneumonia who require hospital admission and have vitamin D deficiency and a positive diagnosis for SARS-Cov-2 (COVID-19)
    Medical condition: COVID-19 infection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-002250-21 Sponsor Protocol Number: 044(D)SC04158 Start Date*: 2005-05-31
    Sponsor Name:ANGELINI
    Full Title: EVALUATION OF ANTALGIC EFFECT AND TOLERABILITY OF A NEW PARACETAMOL SYRUP DOSAGE IN PHARINGOTONSILLYTIS IN PEDIATRY. DOUBLE-BLIND VS PLACEBO STUDY, CONTROLLED VS KETOPROFEN LYSINA SALT.
    Medical condition: ANTALGIC EFFECT AND TOLERABILITY OF A NEW DOSAGE OF PARACETAMOL SYRUP IN PHARINGOTONSILLYTIS IN PEDIATRY
    Disease: Version SOC Term Classification Code Term Level
    6.1 10034835 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-004464-11 Sponsor Protocol Number: CFOR258DVE02 Start Date*: 2016-07-01
    Sponsor Name:Novartis de Venezuela S.A.
    Full Title: Randomized, Double Blind, Double Dummy, Placebo Controlled Trial to Compare the Effectiveness of Formoterol vs Ipatropioum Bromide Plus Fenoterol in Asthmatic Children (5-<12 Years) With Acute Bron...
    Medical condition: Acute Bronchial Obstruction, Asthma
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2016-002210-46 Sponsor Protocol Number: LiSA Start Date*: 2016-07-28
    Sponsor Name:University Medical Centre RadboudUMC
    Full Title: Study: Reduces intravenous lidocaine the need for alfentanyl during colonoscopy under Procedural Sedation and Analgesia?
    Medical condition: patients with IBD, between 18 and 65 years, which are scheduled for a colonoscopy with PSA.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-004161-41 Sponsor Protocol Number: CL-068-II-01 Start Date*: 2005-12-15
    Sponsor Name:Idea AG
    Full Title: Efficacy and Safety of IDEA-068 in Plaque Psoriasis
    Medical condition: chronic stable plaque type psoriasis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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