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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    8,950 result(s) found. Displaying page 27 of 448.
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    EudraCT Number: 2014-001148-40 Sponsor Protocol Number: ExcelsiorLOAD Start Date*: 2014-06-02
    Sponsor Name:Heart Center Freiburg - Bad Krozingen
    Full Title: Pharmacodynamic comparison of thienopyridine loading strategies in patients undergoing elective coronary stenting
    Medical condition: Stable patients with obstructive coronary heart disease undergoing elective percutaneous coronary stent implantation.
    Disease: Version SOC Term Classification Code Term Level
    17.0 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    17.0 100000004865 10069038 Bare metal coronary stent placement LLT
    17.0 100000004865 10069037 Drug-eluting coronary stent placement LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003244-23 Sponsor Protocol Number: SICOG13/02 Start Date*: 2014-03-19
    Sponsor Name:S.I.C.O.G. ONLUS
    Full Title: B-FOLFIRI followed by B-FOLFOX/B-XELOX or the reverse sequence versus standard B-FOLFIRI for the first-line treatment of metastatic colorectal cancer: a randomized SICOG study. SEveSTA study (Seq...
    Medical condition: Unresectable and metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004864 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001218-40 Sponsor Protocol Number: SC12-02 Start Date*: 2012-05-21
    Sponsor Name:FONDAZIONE SANTA LUCIA
    Full Title: EFFICACY OF ROTIGOTINE ON GAIT PERFORMANCE OF PARKINSONIAN PATIENTS
    Medical condition: Patients suffering for Idiopathic Parkinson’s Disease. H&Y stage > or = 2 with un-satisfactory control by on-going pharmacological therapy (Levodopa, COMT & MAO-inhibitors), characterised by an in...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10056242 Parkinsonian gait PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001239-30 Sponsor Protocol Number: CIR976101 Start Date*: 2012-05-22
    Sponsor Name:Foundation for Liver Research
    Full Title: THE EFFECTS OF RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-1 ON THE NUTRITIONAL STATUS IN PATIENTS WITH LIVER CIRRHOSIS: A PILOT-STUDY.
    Medical condition: Liver cirrhosis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10019805 - Hepatobiliary disorders 10024667 Liver cirrhosis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002816-19 Sponsor Protocol Number: Frax001 Start Date*: 2012-10-25
    Sponsor Name:Rijnstate Hospital
    Full Title: Prospective, pharmacokinetic study for determination of the relationship between lean body weight and anti-Xa activity 4 hours after subcutaneous injection of 5700 IU nadroparin in morbidly obese p...
    Medical condition: patients; perioperative in bariatric surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-004785-18 Sponsor Protocol Number: PKBoxing-1 Start Date*: 2014-11-18
    Sponsor Name:University Medical Center Groningen
    Full Title: PET imaging of neuroinflammatory consequences of chronic repetitive head injury in Muay Thai boxing
    Medical condition: n/a
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002161-27 Sponsor Protocol Number: DUETII01 Start Date*: 2016-04-15
    Sponsor Name:Sint Antonius Hospital
    Full Title: Dutch randomized trial comparing Ultrasound-accElerated Thrombolysis with standard dose Urokinase versus half dose Urokinase for thrombo-embolic infra-inguinal arterial disease (DUET II)
    Medical condition: Acute thrombo-embolic occlusion of one of the infra-inguinal arteries
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005700-28 Sponsor Protocol Number: AIDA_104599 Start Date*: 2016-04-20
    Sponsor Name:Erasmus MC
    Full Title: An evaluation of the effectivity of the current treatment of uncomplicated urinary tract infections with fosfomycin.
    Medical condition: Healthy volunteers
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004862 10024981 Lower urinary tract infection LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001959-24 Sponsor Protocol Number: BoTN-Study Start Date*: 2014-08-26
    Sponsor Name:University Hospital Essen
    Full Title: BoTN: Onabotulinumtoxin A for the treatment of trigeminal neuralgia: Efficacy, safety and neurophysiological alterations under therapy – a prospective, controlled trial
    Medical condition: Trigeminal neuralgia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002455-26 Sponsor Protocol Number: IRON-CMR Start Date*: 2014-09-20
    Sponsor Name:Karolinska Institute
    Full Title: The use of intravenous Iron oxide as a contrast agent for cardiac magnetic resonance imaging.
    Medical condition: Cardiovascular diseases: Acute myocardial infarction, chronic myocardial infarction, myocardial ischemia, myocarditis, diffuse myocardial fibrosis.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001417-24 Sponsor Protocol Number: PLEIADES Start Date*: 2017-02-22
    Sponsor Name:Franciscus Gasthuis
    Full Title: POSTPRANDIAL LIPEMIA, INFLAMMATION, AND VASCULAR FUNCTION IN DIABETES MODULATED BY SGLT2 INHIBITION
    Medical condition: Diabetes Mellitus type II
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001541-24 Sponsor Protocol Number: NeuroIPT-1 Start Date*: 2016-03-07
    Sponsor Name:University Medical Center Freiburg
    Full Title: Neuroenhancement of Interpersonal Psychotherapy in Major Depression
    Medical condition: Major Depression (ICD-10; F32.2/F33.2)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004794-41 Sponsor Protocol Number: Vista Start Date*: 2017-03-02
    Sponsor Name:Academical medical centre, dep of internal medicine
    Full Title: Arterial wall inflammation measured with 18F-FDG PET/CT in patients with statin intolerance before and after treatment with a PCSK-9 inhibitor
    Medical condition: Patients with CV-risk and statin intolerance due to statin-associated muscle symptoms (SAMS)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002478-37 Sponsor Protocol Number: 61682 Start Date*: 2018-01-11
    Sponsor Name:VU University Medical Center
    Full Title: Right Dose, Right Now: Randomized Clinical Trial
    Medical condition: Infectious disease, sepsis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004236-38 Sponsor Protocol Number: 12250 Start Date*: 2017-01-24
    Sponsor Name:University of Oxford
    Full Title: OPtimising Treatment for MIld Systolic hypertension in the Elderly: a randomised controlled trial
    Medical condition: Hypertension
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-002636-16 Sponsor Protocol Number: VUMC-ANW-MS-GG-062017 Start Date*: 2017-10-09
    Sponsor Name:VU University medical center Amsterdam
    Full Title: Cognitive impairment and functional reorganization in multiple sclerosis: The role of GABA and glutamate
    Medical condition: Multiple Sclerosis (MS). And specifically cognitive problems in MS.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001260-37 Sponsor Protocol Number: PRODEO Start Date*: 2017-05-23
    Sponsor Name:Zuyderland Medical Center
    Full Title: PRODEO: PROfylactic Haloperidol in patients defined as high risk for DElirium with delirium risk mOdel
    Medical condition: Delirium
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10012218 Delirium PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004735-39 Sponsor Protocol Number: M14NEC Start Date*: 2015-11-10
    Sponsor Name:NKI-AVL
    Full Title: Phase II Study of cisplatin and everolimus in patients with metastatic or unresectable neuroendocrine carcinomas (NEC) of extrapulmonary origin
    Medical condition: Patients with metastatic neuroendocrine carcinomas of extrapulmonary origin will be eligible
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-004119-19 Sponsor Protocol Number: 2015-005-M Start Date*: 2016-04-25
    Sponsor Name:Reinier de Graaf Hospital
    Full Title: Femoral Nerve Blockage in Proximal Femoral Fractures in patients of 65 years of age or older, a Randomised Controlled Trial
    Medical condition: Pain in patients with a proximal femoral fracture.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000042-22 Sponsor Protocol Number: PI16/00720 Start Date*: 2017-05-11
    Sponsor Name:GAP MALLORCA
    Full Title: Randomized, pragmátic, open-label clinical trial with blind evaluator, to evaluate the efficacy efficacy of continuing drug treatment in patients with advanced dementia.
    Medical condition: Advanced dementia
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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