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Clinical trials for Agonists

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    356 result(s) found for: Agonists. Displaying page 3 of 18.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2006-002647-86 Sponsor Protocol Number: BALTI-2, Version 2 Start Date*: 2006-09-25
    Sponsor Name:Heart of England NHS Foundation Trust [...]
    1. Heart of England NHS Foundation Trust
    2. Warwick Medical School
    Full Title: BALTI-2: Beta Agonists in Lung Injury Trial
    Medical condition: Acute respiratory distress syndrome (ARDS)
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-002354-30 Sponsor Protocol Number: ATS K019 / D-Pio-109 Start Date*: 2006-07-27
    Sponsor Name:Takeda Pharma GmbH
    Full Title: Effect of Acute Insulin Intervention followed by Pioglitazone and Metformin Treatment on Metabolic Parameters in Type 2 Diabetic Patients with inadequate Metabolic Control
    Medical condition: Diabetes Type 2
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-004653-29 Sponsor Protocol Number: CIGE025A2432 Start Date*: 2008-05-16
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A randomized, multi-center, double-blind, placebo-controlled, parallel-group trial to explore the effects of 78 weeks omalizumab treatment as add on therapy on airway inflammation and remodeling in...
    Medical condition: Asthma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) NL (Completed) GB (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2005-002109-22 Sponsor Protocol Number: 02/05/Hü Start Date*: 2005-12-01
    Sponsor Name:Medical University of Vienna
    Full Title: Comparative Effects of Telmisartan and Candesartan on glucose metabolism in patients with chronic heart failure
    Medical condition: both investigated drugs are well established in the treatment of heart failure or hypertension respectively. As the investigateed Patients have this conditions according to the inclusion criteria, ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-002237-20 Sponsor Protocol Number: ATS K021 Start Date*: 2006-08-21
    Sponsor Name:Takeda Pharma GmbH
    Full Title: Pilot trial studying the Effects of Pioglitazone in Comparison to Placebo on Myocardial Function and Oxidative Stress in Patients with Type II Diabetes and Insulin Resistance undergoing elective PTCA
    Medical condition: Type 2 diabetic patients treated with oral agents except PPAR gamma agonists and / or patients with insulin resistance measured by IRIS score > 50 with stable coronary artery disease and supposed e...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004989-14 Sponsor Protocol Number: Start Date*: 2007-01-12
    Sponsor Name:Christie Hospital NHS Trust
    Full Title: The Effect of Raloxifene on Serum IGF-I in Patients with Acromegaly on long-term Octeotide Treatment
    Medical condition: acromegaly
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-005061-57 Sponsor Protocol Number: 0633-007 Start Date*: 2008-10-30
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Parallel-Group, Dose- Ranging Study of MK-0633 in Adult Patients with Chronic Asthma
    Medical condition: Treatment of asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-005120-13 Sponsor Protocol Number: VR040/001 Start Date*: 2005-12-21
    Sponsor Name:Vectura Group plc
    Full Title: A clinic based, Phase IIa, randomised, double-blind, placebo-controlled, ascending dose, single centre study investigating the safety, tolerability, efficacy, and pharmacokinetics of VR040 in patie...
    Medical condition: Hypomobility (“off” or “freezing”) episodes associated with advanced Parkinson’s disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-006143-40 Sponsor Protocol Number: IP-001 Start Date*: 2009-07-30
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik Innere Medizin I
    Full Title: Assessment of platelet function in patients with chronic autoimmune thrombocytopenic purpura (cAITP) treated with the thrombopoietin receptor (MPL) agonist Eltrombopag
    Medical condition: patients suffering from chronic autoimmune thrombocytopenia the platelet function/activation will be investigated the rise of reticulated platelets and variation of platelet antibodies will be inve...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-004752-21 Sponsor Protocol Number: ISI-06-01 Start Date*: 2006-11-08
    Sponsor Name:Karolinska Institute, Danderyds hospital
    Full Title: Pertubation with Lignocaine in Endometriosis Associated Symptoms Effect study (PLEASE)
    Medical condition: Women 20-40 years of age with endometriosis and pelvic pain will be included in this study.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10014788 Endometriosis related pain LLT
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2014-005615-17 Sponsor Protocol Number: RPL554-008-2014 Start Date*: 2015-04-22
    Sponsor Name:Verona Pharma plc
    Full Title: A Phase II, randomised, double blind, placebo controlled, seven way crossover study to assess the effect of single doses of RPL554 compared to salbutamol and placebo administered by nebuliser on lu...
    Medical condition: Patients with chronic asthma
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004855 10049106 Asthma chronic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004979-35 Sponsor Protocol Number: 05-FOR-01 SE Start Date*: 2006-11-27
    Sponsor Name:Andi - Ventis
    Full Title: A RANDOMISED, FOUR WAY CROSS-OVER STUDY TO ASSESS BRONCHODILATION, SAFETY AND TOLERABILITY OF NEW GENERIC DRY POWDER FORMOTEROL FORMULATIONS GIVEN AS CUMULATIVE DOSES FROM A NOVEL DRY POWDER INHALE...
    Medical condition: reversible mild asthma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2016-000214-30 Sponsor Protocol Number: P000805 Start Date*: 2017-08-18
    Sponsor Name:Universitätsklinikum Freiburg
    Full Title: Empagliflozin and its effect on heart failure in type 2 diabetes
    Medical condition: Heart failure and type 2 diabetes
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    21.1 100000004861 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000043-10 Sponsor Protocol Number: 200701 Start Date*: 2007-01-30
    Sponsor Name:Fakultní nemocnice Královské Vinohrady
    Full Title: Combination of alpha2-adrenoreceptor agonists, opioids and ketamine for improving of perioperative course
    Medical condition: Praeanaesthetic preparation (premedication) for patients scheduled for laparoscopic cholecystectomy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008611 Cholecystectomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004424-29 Sponsor Protocol Number: 6727 Start Date*: 2018-03-23
    Sponsor Name:Academic Medical Center
    Full Title: Pharmacogenetics Use For Further treatment Improvement in childreN (PUFFIN) trial
    Medical condition: Children with persistent uncontrolled asthma
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002694-37 Sponsor Protocol Number: 507A011 Start Date*: 2016-09-01
    Sponsor Name:Kuopio University hospital
    Full Title: Dexmedetomidine infusion in pain management during low back surgery Dexmedetomidine is an alpha-2-adrenergic agonist that is used mainly for sedation in the intensive care unit. Alpha-2-adre...
    Medical condition: Low back pain, Discus prolapse, Spinal stenosis
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FI (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-003566-13 Sponsor Protocol Number: GLP1-hypofyse Start Date*: 2019-01-02
    Sponsor Name:Radboud university medical center
    Full Title: iPAVE – imaging Pituitary ActiVation by Exendin
    Medical condition: Type 2 diabetes
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000940-17 Sponsor Protocol Number: 64Cu Start Date*: 2018-05-07
    Sponsor Name:
    Full Title: Phase IIa clinical study of 64 CuCl2: efficacy and safety of a new tracer for urologic tumors
    Medical condition: Genitourinary tract tumors in male patients
    Disease:
    Population Age: Elderly Gender: Male
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-005613-38 Sponsor Protocol Number: 44648368 Start Date*: 2006-05-31
    Sponsor Name:Dr. Chris Thompson
    Full Title: Assessment of platelet function in the hypopituitary population. Does hormone replacement therapy alter thrombotic risk?
    Medical condition: Hypopituitarism refers to decreased secretion of pituitary hormones, which can result from diseases of the pituitary gland or from diseases of the hypothalamus, which cause diminished secretion of ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004080-55 Sponsor Protocol Number: CSOM230B2402 Start Date*: 2007-04-26
    Sponsor Name:Erasmus MC
    Full Title: Stepwise Medical Treatment of Cushing’s Disease: a prospective open label multi-center trial with SOM230 mono- and combination therapy with dopamine agonists and ketoconazole
    Medical condition: The medical condition to be investigated is Cushing's disease which is caused by an ACTH producing pituitary adenoma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011651 Cushing's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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