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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44337   clinical trials with a EudraCT protocol, of which   7367   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,337 result(s) found. Displaying page 309 of 2,217.
    EudraCT Number: 2006-001999-20 Sponsor Protocol Number: RD.03.SPR.40027 Start Date*: 2006-10-10
    Sponsor Name:Galderma Research & Development SNC
    Full Title: ASSESSMENT OF THE EFFICACY AND SAFETY OF THREE CONCENTRATIONS: 1%, 0.3%, 0.1% OF CD5024 CREAM ONCE DAILY AND CD5024 1% CREAM TWICE DAILY, VERSUS ITS VEHICLE AND VERSUS METRONIDAZOLE 0.75% CREAM (RO...
    Medical condition: Patients with papulo-pustular rosacea
    Disease: Version SOC Term Classification Code Term Level
    9.0 10039218 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001818-16 Sponsor Protocol Number: LT-CLL-001 Start Date*: 2007-07-05
    Sponsor Name:Vilnius University Hospital Santariskiu Clinics
    Full Title: Phase II Study of High-dose Methylprednisolone and Rituximab in Previously Treated Patients with High Risk Chronic B Lymphocytic Leukemia
    Medical condition: Treated high-risk chronic B lymphocytic leukemia.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003947 B-Lymphocytic, CLL (Kiel Classification) recurrent LLT
    9.1 10003948 B-Lymphocytic, CLL (Kiel Classification) refractory LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002786-39 Sponsor Protocol Number: SAREFU Start Date*: 2007-09-14
    Sponsor Name:AZIENDA OSPEDALIERA "OSPEDALI RIUNITI DI BERGAMO" (A.O. DI RILIEVO NAZIONALE)
    Full Title: A PROSPECTIVE TRIAL , MONOCENTRIC, RANDOMIZED, TO EVALUATE THE RENAL'S FUNCTION IN SUBJECTS WITH CARDIAC TRANSPLANTED
    Medical condition: CARDIAC-TRASPLATED
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048870 Prophylaxis against transplant rejection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002202-54 Sponsor Protocol Number: Dandrit 02, April 2006 Start Date*: 2006-06-21
    Sponsor Name:Dandrit Biotech A/S
    Full Title: Vaccination med autologe dendritiske celler pulset med allogent tumorlysat (MelCancerVac) til behandling af patienter med avanceret eller metastatisk ikke-småcellet lungecancer
    Medical condition: avanceret eller metastatisk ikke-småcellet lungecancer
    Disease: Version SOC Term Classification Code Term Level
    7.1 10029520 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002208-32 Sponsor Protocol Number: PAR06 Start Date*: 2006-08-14
    Sponsor Name:York Hospital NHS Trust
    Full Title: A comparison of the analgesic efficacy of oral and intravenous paracetamol (perfalgan) in a day case setting
    Medical condition: We will perform a double blind randomised comparison of oral paracetamol versus intravenous paracetamol (Perfalgan) in patients undergoing knee arthroscopy in a day surgery setting.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-011345-43 Sponsor Protocol Number: 09-07 Start Date*: 2009-05-18
    Sponsor Name:CHU de GRENOBLE
    Full Title: « Etude contrôlée randomisée versus placebo évaluant l’efficacité de Gelsemium sempervirens (5CH et 15CH) sur l’anxiété anticipatoire provoquée, chez des volontaires sains. »
    Medical condition: L’anxiété état peut apparaître au cours d’évènements banaux et dépourvus de facteurs objectivement angoissants, elle est prépondérante dans des situations particulières, comme les examens et concou...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002273-12 Sponsor Protocol Number: Onco2008 Start Date*: 2008-06-23
    Sponsor Name:OSPEDALE POLICLINICO S. MATTEO
    Full Title: Long term opioid administration in oncologic chronic pain: open label, prospective study on efficacy, safety and pharmacogenetic factors.
    Medical condition: oncologic chronic pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10058019 Cancer pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-002281-55 Sponsor Protocol Number: RH007 Start Date*: 2008-08-29
    Sponsor Name:Merck Farma y Química S.L
    Full Title: Estudio exploratorio para determinar el efecto de lutropina alfa en la calidad de los embriones y su implantación en mujeres de edad reproductiva avanzada
    Medical condition: Determinar el efecto de la lutropina alfa en la calidad de embriones y su implantación en mujeres de edad reproductiva avanzada.
    Disease: Version SOC Term Classification Code Term Level
    7.0 10003539 PT
    Population Age: Adults Gender: Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-002309-38 Sponsor Protocol Number: CASA404A2302 Start Date*: 2008-12-22
    Sponsor Name:Novartis Farmacéutica, S.A.
    Full Title: Estudio Fase III, multicéntrico, aleatorizado, doble ciego, controlado con placebo, de ASA404 en combinación con docetaxel, como tratamiento de segunda línea para pacientes con cáncer de pulmón de ...
    Medical condition: Pacientes con cancer de pulmón de célula no pequeña, estadio IIIb/IV que han progresado durante o tras recibir una primera linea de quimioterapia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066490 Progression of non small cell lung cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) BE (Completed) DE (Prematurely Ended) IT (Prematurely Ended) GB (Completed) HU (Prematurely Ended) PL (Prematurely Ended) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-005660-27 Sponsor Protocol Number: OP-P-5265-1 Start Date*: 2008-02-13
    Sponsor Name:OraPharma Inc.
    Full Title: Multi-Center Phase 3 Trial of Minocycline HCl 1mg Microspheres for the Use in Subjects with Peri-Implantitis
    Medical condition: peri-implantitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10034539 Periodontitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-007768-41 Sponsor Protocol Number: CA196-005 Start Date*: 2009-10-16
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Randomized Double-Blinded Phase II Study of Carboplatin/Paclitaxel/CT-322 versus Carboplatin/Paclitaxel/Bevacizumab as First-Line Treatment for Recurrent or Advanced Non-Small Cell Lung Cancer wi...
    Medical condition: Recurrent or Advanced Non-Small Cell Lung Cancer with Non-Squamous Histology
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061873 Non-small cell lung cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-007784-16 Sponsor Protocol Number: IL1T-GA-0815 Start Date*: 2010-01-05
    Sponsor Name:Regeneron Pharmaceuticals Inc.
    Full Title: A Multi-Center, Randomized, Double-Blind, Placebo Controlled Trial of the Safety of Rilonacept for the Prophylaxis of Gout Flares in Patients on Urate Lowering Therapy.
    Medical condition: Gout flares
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064900 Gout flare LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-006742-18 Sponsor Protocol Number: P070106 Start Date*: 2010-08-25
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Evaluation de l'intérêt de la loxapine dans le contrôle de l'agitation au cours du sevrage de la ventilation mécanique. Etude randomisée, contrôlée.
    Medical condition: Agitation au cours du sevrage de la ventilation mécanique
    Disease: Version SOC Term Classification Code Term Level
    8.1 10067221 Ventilation mécanique PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-006761-32 Sponsor Protocol Number: A 091152 Start Date*: 2008-04-15
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: Vulval intraepithelial neoplasia: immune responses to human papillpmavirus.
    Medical condition: Vulval intraepithelial neoplasia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056574 Vulval intraepithelial neoplasia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-004756-69 Sponsor Protocol Number: M/100977/24 Start Date*: 2008-10-21
    Sponsor Name:Laboratorios Almirall, S.A.
    Full Title: A randomised, double-blind, placebo-controlled, 4-way crossover clinical trial to assess the efficacy, safety, tolerability and pharmacokinetics of single doses of LAS100977 administered by inhalat...
    Medical condition: Adult male subjects, aged 18 to 70 years, clinically diagnosed of persistent asthma (according to GINA guidelines 2007 update) for at least 6 months before screening, but who are otherwise in good ...
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-011743-39 Sponsor Protocol Number: CAFQ056A2207 Start Date*: 2009-09-18
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multi-centre, randomized, double-blind, placebo-controlled, parallel-group, multiple oral dose titration Proof of Concept study in patients with Huntington's disease to assess the efficacy, safet...
    Medical condition: Huntington's disease
    Disease: Version SOC Term Classification Code Term Level
    13.1 10010331 - Congenital, familial and genetic disorders 10020469 Huntington's chorea LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-001571-37 Sponsor Protocol Number: AAV2/2-hRPE65p-hRPE65 Start Date*: 2006-12-14
    Sponsor Name:University College London
    Full Title: AN OPEN-LABEL DOSE ESCALATION STUDY OF AN ADENO-ASSOCIATED VIRUS VECTOR (AAV2/2-hRPE65p-hRPE65) FOR GENE THERAPY OF SEVERE EARLY-ONSET RETINAL DEGENERATION
    Medical condition: The condition to be investigated is severe early-onset inherited retinal degeneration due to defects in the gene encoding RPE65
    Disease: Version SOC Term Classification Code Term Level
    13.1 10015919 - Eye disorders 10038845 Retinal degeneration PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-001578-25 Sponsor Protocol Number: P04334 Start Date*: 2007-02-12
    Sponsor Name:Schering-Plough Research Institute, a division of Schering Corporation
    Full Title: A 26-Week Placebo-Controlled Efficacy and Safety Study of Mometasone Furoate/Formoterol Fumarate Combination Formulation Compared With Mometasone Furoate and Formoterol Monotherapy in Subjects with...
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003553 Asthma LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) EE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-001595-20 Sponsor Protocol Number: CRAD001J2102 Start Date*: 2006-11-23
    Sponsor Name:NOVARTIS FARMA
    Full Title: A phase Ib study investigating the combination of RAD001 with trastuzumab and vinorelbine in patients with HER2- overexpressing metastatic breast cancer
    Medical condition: HER2 overexpressing metastatic breast cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021977 Inflammatory carcinoma of breast recurrent LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-002940-28 Sponsor Protocol Number: ISRCTN46528154 Start Date*: 2006-10-09
    Sponsor Name:ICIN [...]
    1. ICIN
    2. UMCG, Van Buchem Stichting
    Full Title: HEBE III: A prospective, randomised, double blind, placebo controlled clinical study to examine the effects of a single bolus erythropoietin on left ventricular function in patients with an acute m...
    Medical condition: Patients with a successful primary PCI (TIMI 2/3) for a first acute myocardial infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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