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Clinical trials for Chronic Pain

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,162 result(s) found for: Chronic Pain. Displaying page 4 of 59.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2009-009857-17 Sponsor Protocol Number: 42160443PAI2003 Start Date*: 2009-12-16
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Dose-Loading Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42160443 as Adjunctive Therapy in Subjects With Inadequate...
    Medical condition: Moderate to severe, chronic, low back pain (LBP) that is not adequately controlled by standard pain therapy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024891 Low back pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended) BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-005722-35 Sponsor Protocol Number: H--6-2014-070 Start Date*: 2015-06-23
    Sponsor Name:Glostrup University Hospital
    Full Title: Measures of inflammation in low back pain (LBP) and anti-TNFα for the treatment of deemed discogenic LBP - an explorative study
    Medical condition: Low back pain with and without legg-pain In the late periode 1990ies it became clear that various cytokines and other inflammatory elements played a large role for low back pain. One of the known ...
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10024891 Low back pain LLT
    18.0 100000004859 10024892 Low back pain (without radiation) LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-004609-85 Sponsor Protocol Number: UV2005/01 Start Date*: 2008-03-18
    Sponsor Name:OM Pharma SA
    Full Title: Multicentre, randomised, double-blind, placebo-controlled clinical study to assess the efficacy and safety of UroVaxom in chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS)
    Medical condition: Chronic prostatitis and chronic pelvic pain syndrome
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038604 - Reproductive system and breast disorders 10064189 Chronic pelvic pain syndrome LLT
    14.1 10038604 - Reproductive system and breast disorders 10009109 Chronic prostatitis LLT
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed) AT (Completed) PT (Completed)
    Trial results: View results
    EudraCT Number: 2009-015397-35 Sponsor Protocol Number: KF5503/53 Start Date*: 2010-02-12
    Sponsor Name:Grünenthal GmbH
    Full Title: A multicenter, open-label trial to assess cognitive and psychomotor performance as surrogate parameters for driving ability under stable long term treatment with tapentadol hydrochloride prolonged-...
    Medical condition: Pain
    Disease: Version SOC Term Classification Code Term Level
    14.0 10018065 - General disorders and administration site conditions 10033371 Pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-022955-43 Sponsor Protocol Number: A0081256 Start Date*: 2011-05-17
    Sponsor Name:Pfizer Limited, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK
    Full Title: OPEN LABEL EUROPEAN STUDY TO SUPPORT THE EARLY IDENTIFICATION OF PATIENTS WITH CHRONIC NEUROPATHIC LOW BACK PAIN IN PRIMARY CARE AND TO ASSESS THE EFFECTIVENESS AND TOLERABILITY OF PREGABALIN IN TH...
    Medical condition: Pregabalin (Lyrica ®) is approved in the European Union for the treatment of peripheral and central neuropathic pain in adults. The medical condition being investigated in this study is chronic neu...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029205 - Nervous system disorders 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) GR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-000557-35 Sponsor Protocol Number: NW-1029/001/II/2003 Start Date*: 2005-06-09
    Sponsor Name:Newron Pharmaceuticals SpA
    Full Title: A phase II, multi centre, pilot, randomised, ascending dose, double -blind, placebo controlled, dose titration study to determine the safety, maximum tolerated dose and preliminary evidence of effi...
    Medical condition: Neuropathic pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-012586-55 Sponsor Protocol Number: Protocol_DNIC_2009 Start Date*: 2009-08-27
    Sponsor Name:Leiden University Medical Center
    Full Title: Influence of S(+)-ketamine on Diffuse Noxious Inhibitory Control (DNIC) and offset analgesia (OA) in chronic pain patients (neuropathic pain, complex regional pain syndrome type 1, fibromyalgia) an...
    Medical condition: Chronic pain patients: CRPS-1, fibromyalgia and neurptahic pain
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-000487-27 Sponsor Protocol Number: 0663-806 Start Date*: 2004-08-10
    Sponsor Name:Merck Sharp & Dohme (Sweden) AB
    Full Title: A Double-Blind, Parallel-Group, 4-week Trial to Assess the Efficacy and Safety of Etoricoxib 60mg and Diclofenac 150mg in Patients with Chronic Low Back Pain
    Medical condition: Chronic Low Back Pain
    Disease: Version SOC Term Classification Code Term Level
    7.0 10008837 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) HU (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-005187-24 Sponsor Protocol Number: OROS-ANA-3001 Start Date*: 2005-08-16
    Sponsor Name:JANSSEN-CILAG
    Full Title: Randomized, open label, comparative parallel group study to assess efficacy and safety of flexible dosages of OROS hydromorphone once-daily compared to sustained release oxycodone twice-daily in su...
    Medical condition: Treatment of chronic non-malignant pain
    Disease: Version SOC Term Classification Code Term Level
    6.1 10033371 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) DE (Completed) CZ (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2019-001260-29 Sponsor Protocol Number: CCH01 Start Date*: 2019-09-10
    Sponsor Name:CCH Pharmaceuticals
    Full Title: Proof of concept study for evaluation of the effect of ketamine intranasal spray in treatment of chronic Cluster Headache (CCH)
    Medical condition: Chronic Cluster Headache
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10059133 Cluster headache PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-000095-10 Sponsor Protocol Number: BATCP Start Date*: 2015-03-30
    Sponsor Name:Karolinska Institutet
    Full Title: Botulinum toxin-A as a treatment for chronic muscle-related pain in adults with spastic cerebral palsy: a randomized controlled trial.
    Medical condition: Spastic cerebral palsy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-024320-23 Sponsor Protocol Number: I4F-EW-CCAC Start Date*: 2011-03-08
    Sponsor Name:Chorus, Eli Lilly and Company
    Full Title: A Proof-of-Concept Study of the Effects of LY2828360 in the Treatment of Patients with Osteoarthritic Knee Pain
    Medical condition: Pain in osteoarthritic knee.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10018065 - General disorders and administration site conditions 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-004888-31 Sponsor Protocol Number: OXN3508 Start Date*: 2015-01-26
    Sponsor Name:Mundipharma Research GmbH & Co. KG
    Full Title: A randomised, double-blind, double-dummy, cross-over multicenter study to demonstrate equivalence in analgesic efficacy and bowel function taking oxycodone equivalents of 120 and 160 mg per day as ...
    Medical condition: The intended indication is: Chronic severe non malignant pain, chronic severe malignant pain, requiring opioids.
    Disease: Version SOC Term Classification Code Term Level
    18.0 10018065 - General disorders and administration site conditions 10033371 Pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-017470-20 Sponsor Protocol Number: GRT-CG5503-2009-02-FR Start Date*: 2010-05-07
    Sponsor Name:Laboratoires Grünenthal
    Full Title: An open-label extension study for patients with severe chronic low back pain or severe chronic pain due to knee osteoarthritis who have completed any of the previous phase IIIb trials with tapentad...
    Medical condition: Severe chronic pain
    Disease: Version SOC Term Classification Code Term Level
    12.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-010428-25 Sponsor Protocol Number: KF5503/45 Start Date*: 2010-02-15
    Sponsor Name:Grünenthal GmbH
    Full Title: An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with severe chronic nocicept...
    Medical condition: Low back Pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024891 Low back pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) NL (Completed) DE (Completed) FR (Completed) BE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2014-005035-13 Sponsor Protocol Number: GaPP2 Start Date*: 2015-02-13
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: GaPP 2: A multi-centre randomised controlled trial of the efficacy and mechanism of action of gabapentin for the management of chronic pelvic pain in women
    Medical condition: Chronic pelvic pain of unknown cause
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004872 10048581 Pelvic pain female LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-006390-24 Sponsor Protocol Number: DISCI-Studie Start Date*: 2007-03-23
    Sponsor Name:WALA Heilmittel GmbH
    Full Title: Prospektive, randomized, controlled, multicentre, partly double blind study to compare Disci/Rhus toxicodendron comp., placebo and waiting list in patients with chronic low back pain.
    Medical condition: chronic low back pain (chronic local or pseudoradiculaere low back pain due to e.g. degenerative basic illness).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-001586-32 Sponsor Protocol Number: GN12RE072 Start Date*: 2012-12-13
    Sponsor Name:NHS Greater Glasgow and Clyde
    Full Title: The role of Qutenza (topical capsaicin 8%) in the treatment of chronic pain from critical ischaemia in patients with end stage renal failure
    Medical condition: Chronic pain from critical limb ischaemia in patients with end-stage renal failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-000815-42 Sponsor Protocol Number: HighNxGHR_PK Start Date*: 2015-04-28
    Sponsor Name:Rigshospitalet, Copenhagen University Hospitals
    Full Title: Pharmacokinetics of High-dose Target-controlled Naloxone Infusion. Companion study to: Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia in Patients following Groin-H...
    Medical condition: Healthy subjects
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004867 10049475 Chronic pain LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005701-20 Sponsor Protocol Number: ANST2015_1 Start Date*: 2015-05-20
    Sponsor Name:Leiden University Medical Center
    Full Title: Shifting pain modulation towards anti-nociceptivity: Mechanism-specific pharmacological prevention of post sternotomy pain: the MASTER study
    Medical condition: chronic pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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