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Clinical trials for Heart surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    628 result(s) found for: Heart surgery. Displaying page 4 of 32.
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    EudraCT Number: 2008-003831-20 Sponsor Protocol Number: 2008/27 Start Date*: 2008-11-18
    Sponsor Name:Hopital Foch
    Full Title: Comparaison de l'effet de deux doses d'Acide Tranexamique sur les besoins transfusionnels en chirurgie cardiaque
    Medical condition: cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048935 Open heart surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018767-42 Sponsor Protocol Number: CEUS-TEVAR-29 Start Date*: 2011-05-06
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: The use of Contrast Enhanced Transesophageal Echocardiography in thoracic endovascular aortic repair (TEVAR). Feasibility and safety of a new tool for intraoperative monitoring and follow up.
    Medical condition: descending thoracic aorta diseases
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-001086-32 Sponsor Protocol Number: 19-001_AMG Start Date*: 2020-01-02
    Sponsor Name:RWTH Aachen University represented by the Rector himself, represented by the Dean of the Medical Faculty
    Full Title: ADVANCE-CSX Pilot – Antioxidant Treatment with Vitamin C in Cardiac Surgery Patients – a Clinical Pilot Study
    Medical condition: Patients undergoing high-risk open-heart surgery with the use of cardiopulmonary bypass (CPB)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004596-31 Sponsor Protocol Number: NL62772 Start Date*: 2019-03-25
    Sponsor Name:UMC Utrecht
    Full Title: CeRebrUm and CardIac protection with Allopurinol in neonates with critical congenital heart disease requiring cardiac surgery with cardiopulmonary bypass
    Medical condition: Brain injury in neonates with critical congenital heart disease requiring cardiac surgery with cardiopulmonary bypass.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10010495 Congenital heart disease NOS LLT
    20.0 10029205 - Nervous system disorders 10067967 Brain injury PT
    Population Age: Newborns, Under 18 Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-003995-65 Sponsor Protocol Number: TAKICARD-1 Start Date*: 2015-11-25
    Sponsor Name:Västra Götalandsregionen, Sahlgrenska University Hospital /Queen Silvia children's hospital
    Full Title: Pharmacokinetics of ANP, a diuretic hormone, in neonates undergoing surgery for congenital heart defects. A pilot study.
    Medical condition: Acute renal failure after heart surgery
    Disease: Version SOC Term Classification Code Term Level
    18.0 10038359 - Renal and urinary disorders 10038447 Renal failure neonatal PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-004307-20 Sponsor Protocol Number: Start Date*: 2012-02-09
    Sponsor Name:Reino Pöyhiä
    Full Title: Comparison of periosteal and subcutaneous infusions of articaine and bupivacaine in treatment of acute pain after sternotomy
    Medical condition: Patients undergoing elective open aortic or mitral valve, atrial septal defect or myxoma surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10048935 Open heart surgery LLT
    14.1 10022117 - Injury, poisoning and procedural complications 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-012372-27 Sponsor Protocol Number: 200901 Start Date*: 2009-09-17
    Sponsor Name:LUMC
    Full Title: The Sevoflurane study, understanding the effects of Sevoflurane to improve safety and outcome of cardiac surgery
    Medical condition: myocardial ischemia reperfusion injury during cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-000444-22 Sponsor Protocol Number: NL75930.078.20 Start Date*: 2021-04-07
    Sponsor Name:Erasmus MC
    Full Title: Differences in coagulation between fresh frozen plasma and Solventdetergent plasma in pediatric congenital heart surgery
    Medical condition: coagulation in pediatric cardiac surgery
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-004672-35 Sponsor Protocol Number: PACS2019 Start Date*: 2020-01-10
    Sponsor Name:Institution for Clinical Science, Karolinska Institutet
    Full Title: Open heart surgery – does it have to hurt that much? PACS – Parasternal After Cardiac Surgery. A prospective randomised study to assess the analgesic effect of a continuous bilateral parasternal bl...
    Medical condition: The analgesic effect of continuous bilateral parasternal infusion of local anaesthetic after open cardiac surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2014-003589-25 Sponsor Protocol Number: Levo-AKI Start Date*: 2014-11-11
    Sponsor Name:Sahlgrenska Universitetssjukhuset/Sahlgrenska
    Full Title: The effect of levosimendan, on renal blood flow, function and oxygen uptake during acute renal failure after cardiac surgery
    Medical condition: Acute kidney injury postoperatively in connection with heart surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012624-93 Sponsor Protocol Number: BREVI Start Date*: 2009-06-08
    Sponsor Name:OSPEDALE S. RAFFAELE
    Full Title: “Esmolol in cardiac surgery. A randomized controlled trial with clinical relevant endpoints.”
    Medical condition: patients undergoing cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020823 Hypertensive heart disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2011-003695-36 Sponsor Protocol Number: Start Date*: 2012-09-07
    Sponsor Name:Brighton & Sussex University Hospitals NHS Trust
    Full Title: Is intravenous iron and darbepoetin more effective than oral iron in reducing blood transfusion requirements for patients undergoing cardiac surgery
    Medical condition: Anaemia
    Disease: Version SOC Term Classification Code Term Level
    14.1 10005329 - Blood and lymphatic system disorders 10066761 Acute anaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-002427-28 Sponsor Protocol Number: CIT-003-01 Start Date*: 2018-10-24
    Sponsor Name:Asklepion Pharmaceuticals, LLC
    Full Title: A Phase III Double-Blind, Randomized, Placebo Controlled, Multi-Center Clinical Study to Evaluate the Efficacy and Safety of Intravenous L-citrulline for the Prevention of Clinical Sequelae of Acut...
    Medical condition: Post-operative pulmonary dysfunction induced by cardiopulmonary bypass in pediatric subjects undergoing surgery for congenital heart defects.
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004051-35 Sponsor Protocol Number: INSTEM_HHU_2005 Start Date*: 2006-09-01
    Sponsor Name:University Hospital Düsseldorf
    Full Title: Intramyocardial Application of Stem Cells in combination with transmyocardial Laser Revascularisation (TMLR) in CABG Patients
    Medical condition: Other forms of chronic ischaemic heart disease
    Disease: Version SOC Term Classification Code Term Level
    70 10032058 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017752-28 Sponsor Protocol Number: MSCII Start Date*: 2010-03-22
    Sponsor Name:Cardiovascular laboratory 2014, The Heart Centre, Rigshospitalet [...]
    1. Cardiovascular laboratory 2014, The Heart Centre, Rigshospitalet
    2. Cardiovascular laboratory 2014, The Heart Centre, Rigshospitalet
    Full Title: Stamcellebehandling af patienter med kronisk kranspulsåresygdom MesenchYmal STROMAL CELL therapy in patients with chronic myocardial ischemia (MyStromalCell Trial)
    Medical condition: Patients with severe stable coronary artery disease on medical therapy and no further revascularisation options with balloon angioplasty or coronary artery by-pass surgery and still severe angina p...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10008937 Chronic ischemic heart disease, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-007174-35 Sponsor Protocol Number: AM-KS-IV/5/07 Start Date*: Information not available in EudraCT
    Sponsor Name:Dr. Franz Köhler Chemie GmbH
    Full Title: Randomized, placebo-controlled phase-IV clinical trial for the application of physostigmine salicylate for an early post-operative restoration of vigilance and cognition after cardiopulmonary bypas...
    Medical condition: post-operative restoration of vigilance and cognition after cardiopulmonary bypass surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066123 Cardiopulmonary bypass LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-002494-19 Sponsor Protocol Number: NL61864.041.17 Start Date*: 2017-12-21
    Sponsor Name:UMC Utrecht
    Full Title: Dexamethasone for Cardiac Surgery trial: a novel 'Standard Practice Preference-Randomised Consent' Design. A PILOT STUDY
    Medical condition: Inflammatory response to cardiac surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-003046-13 Sponsor Protocol Number: 2021/ABM/03/00008 Start Date*: 2023-11-27
    Sponsor Name:Śląskie Centrum Chorób Serca
    Full Title: Sacubitril/Valsartan in PriMAry preventIoN of the cardiotoxicity of systematic breaST canceR trEAtMent. Randomized, multicenter, double-blind, placebo-controlled study.
    Medical condition: Heart failure – post-anthracycline cardiomyopathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-001027-33 Sponsor Protocol Number: PAFIBAR1.0 Start Date*: 2023-06-07
    Sponsor Name:FIMABIS
    Full Title: Evaluation of the effect of Opioid-Free Anesthesia on oxygenation in bariatric surgery
    Medical condition: Bariatric surgery
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10068900 Bariatric surgery LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000191-41 Sponsor Protocol Number: GC28210 Start Date*: 2012-06-19
    Sponsor Name:GENENTECH, Inc.
    Full Title: A PHASE II, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND STUDY OF THE SAFETY AND EFFICACY OF MPSK3169A IN PATIENTS WITH CORONARY HEART DISEASE OR HIGH RISK OF CORONARY HEART DISEASE
    Medical condition: Coronary Heart Disease or High Risk of Coronary Heart Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10068617 Coronary heart disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) CZ (Completed) SK (Completed)
    Trial results: View results
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