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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44343   clinical trials with a EudraCT protocol, of which   7372   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,343 result(s) found. Displaying page 422 of 2,218.
    «« First « Previous 418  419  420  421  422  423  424  425  426  Next» Last»»
    EudraCT Number: 2005-000755-15 Sponsor Protocol Number: 1974 Start Date*: 2005-10-25
    Sponsor Name:University Hospital of Birmingham Foundation Trust
    Full Title: Perhexiline therapy in patients with Hypertrophic Cardiomyopathy
    Medical condition: Hypertrophic Cardiomyopathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-004268-21 Sponsor Protocol Number: NC19794 Start Date*: 2006-02-17
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: A multicenter, open label, extension study to evaluate the long-term safety and tolerability of RO4389620 in type 2 diabetic patients from studies BM18248 or BM18249.
    Medical condition: Type 2 diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    7 10012613 low
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) HU (Prematurely Ended) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-004271-37 Sponsor Protocol Number: E7389-G000-204 Start Date*: 2006-01-20
    Sponsor Name:Eisai Limited
    Full Title: A Phase II Multicenter, Open Label, Two-Stage Design Study Evaluating E7389 in Patients with Hormone Refractory Prostate Cancer with Advanced and/or Metastatic Disease Stratified by Prior Chemother...
    Medical condition: Advanced/metastatic hormone-refractory prostate cancer.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10060862 Prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed) ES (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2007-001503-38 Sponsor Protocol Number: PolEver Start Date*: 2008-06-05
    Sponsor Name:AZIENDA OSPEDALIERA PROVINCIALE DI LECCO
    Full Title: effect of everolimus on adult polycystic nephropaty; a study pilot
    Medical condition: Autosomal Dominant Plycystic Kidney Disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010607 Congenital renal cyst LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001534-13 Sponsor Protocol Number: V58P12 Start Date*: 2007-11-08
    Sponsor Name:Novartis Vaccines and Diagnostics S.r.l.
    Full Title: A Combined Phase II/III, Observer-Blind, Randomized, Multi-center Study to Evaluate Safety, Tolerability and Immunogenicity of Trivalent Subunit Influenza Vaccines, Produced Either in Mammalian Cel...
    Medical condition: Healthy pediatric population from 3-17 years
    Disease:
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) LT (Completed) FI (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-002350-63 Sponsor Protocol Number: SL300/2004/002/D Start Date*: 2004-11-19
    Sponsor Name:Stallergenes GmbH & Co.KG
    Full Title: Efficacy and Safety of Sublingual Immunotherapy with Ultra-Rush Titration in Children with Allergic Rhinoconjunctivitis to Tree Pollen, a Multicentre DBPC Trial
    Medical condition: Allergic rhinitis against birch pollen
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004374-90 Sponsor Protocol Number: D6160C00055 Start Date*: 2005-04-01
    Sponsor Name:AstraZeneca AB
    Full Title: A 24-Week Randomized, Double-Blind, Parallel-Group, Multi-Centre, Placebo-Controlled Study to Evaluate the Efficacy, Safety and Tolerability of Tesaglitazar Therapy when Administered as Monotherapy...
    Medical condition: Men or women who are 18 years of age or more at enrolment (visit 1). The patients should be drug-naïve with Type 2 diabetes and not on anti-diabetic treatment during the recent 24 weeks.
    Disease: Version SOC Term Classification Code Term Level
    7 10045242 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) SK (Completed) CZ (Completed) LT (Completed) LV (Completed) EE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004399-35 Sponsor Protocol Number: Pfi-RW-2005-01 Start Date*: 2005-01-18
    Sponsor Name:North Glasgow Trust
    Full Title: The effects of eplerenone on left ventricular remodelling post-acute myocardial infarction: a double-blind placebo-controlled cardiac MR-based study.
    Medical condition: Post-myocardial infarction left ventricular dysfunction, in the absence of heart failure - clinical (i.e. Killip III or IV) or radiological - nor established diabetes mellitus.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003821-25 Sponsor Protocol Number: HIL-01 Start Date*: 2005-10-11
    Sponsor Name:Psychiatric Hospital
    Full Title: A 12 week multi-centre, randomized, double-blind, placebo controlled evaluation of the most efficacious and tolerable dose of escitalopram in the treatment of elderly patients.
    Medical condition: Depression in the elderly
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-001433-17 Sponsor Protocol Number: Hx-CD20-405 Start Date*: 2006-06-30
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A single-arm, international, multi-center trial of HuMax-CD20, a fully human monoclonal anti-CD20 antibody, in patients with Follicular Lymphoma who are refractory to rituximab as monotherapy or in...
    Medical condition: Non-Hodgkin Follicular Lymphoma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10003899 B-cell lymphoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) SE (Completed) DK (Prematurely Ended) DE (Completed) ES (Completed) NL (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-005393-73 Sponsor Protocol Number: ERLOPET_01 Start Date*: 2007-09-14
    Sponsor Name:University Cologne
    Full Title: A Phase II Clinical Trial to Evaluate the Accuracy of FDG-/FLT- PET for Early Prediction of Non-Progression in Patients with Advanced Non Small Cell Lung Cancer (NSCLC) treated with Erlotinib and t...
    Medical condition: The trial will be conducted in patients with non-small cell lung cancer in stage IIIb - IV
    Disease: Version SOC Term Classification Code Term Level
    8.1 10029521 Non-small cell lung cancer stage IIIB LLT
    9.1 10029522 Non-small cell lung cancer stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005715-10 Sponsor Protocol Number: 2006PC008B Start Date*: 2007-10-09
    Sponsor Name:Royal Brompton & Harefield NHS Trust
    Full Title: The Control of Hyperglycaemia In Paediatric intensive care (The CHIP Trial).
    Medical condition: hyperglycaemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020635 Hyperglycaemia LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005731-16 Sponsor Protocol Number: TG-M-005 Start Date*: 2007-01-05
    Sponsor Name:ThromboGenics Ltd.
    Full Title: An Open Label Clinical Trial of Microplasmin Administered via the Trellis-8 Infusion System for the Treatment of Acute Iliofemoral Deep Vein Thrombosis
    Medical condition: Acute Iliofemoral Deep Vein Thrombosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003562-42 Sponsor Protocol Number: AdjuVIT v3 Start Date*: 2006-09-27
    Sponsor Name:Queen Mary, University of London
    Full Title: Trial of Adjunctive Vitamin D in Tuberculosis Treatment (AdjuVIT)
    Medical condition: Pulmonary tuberculosis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10037440 Pulmonary tuberculosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002328-40 Sponsor Protocol Number: HHSC/005 Start Date*: 2007-05-18
    Sponsor Name:Imperial College London
    Full Title: A phase I safety and tolerability study of infusing the autologous progeny of an adult CD34+ subset into patients with type I diabetes mellitus and a successful renal transplant.
    Medical condition: Diabetes mellitus type 1 and succesful renal transplant
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012638 Diabetes with renal manifestations LLT
    9.1 10038533 Renal transplant LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002338-39 Sponsor Protocol Number: 17 Start Date*: 2006-12-22
    Sponsor Name:Universitätsklinikum Heidelberg
    Full Title: Pharmakokinetik von Linezolid bei Dialyse (pharmacokinetics of linezolid under dialysis)
    Medical condition: acute renal failure and infection or sepsis without acute renal failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-003080-31 Sponsor Protocol Number: 172003 Start Date*: 2006-12-12
    Sponsor Name:NV Organon
    Full Title: A multi-center, double-blind, flexible-dose efficacy trial with Org 25935 versus placebo as add-on therapy in subjects with predominant, persistent negative symptoms of schizophrenia treated with a...
    Medical condition: Schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039626 Schizophrenia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed) FI (Completed) FR (Completed) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-002913-11 Sponsor Protocol Number: DOP 06 Start Date*: 2006-07-31
    Sponsor Name:York Hospitals NHS Trust
    Full Title: Randomised controlled, double blinded single centre trial to assess the effects of peri-operative dopexamine on morbidity after major abdominal surgery in patients with low anaerobic threshold.
    Medical condition: Patients undergoing scheduled resection for carcinoma of the colon, rectum, bladder, pancreas, stomach or kidney, who, after routine CPX testing at the Pre-assessment Clinic, have been found to hav...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-006591-37 Sponsor Protocol Number: 0881K1-3329 Start Date*: 2007-10-25
    Sponsor Name:Wyeth Pharmaceuticals France
    Full Title: A 3 Month, Randomised, Open Label, Parallel Group, Descriptive Study to Explore and Compare Perceptions and Satisfaction for Two Different Delivery Mechanisms for Etanercept (Etanercept Auto-Inject...
    Medical condition: Rheumatoid Arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GR (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-006619-64 Sponsor Protocol Number: 2006SG005 Start Date*: 2007-07-04
    Sponsor Name:University Hospital of South Manchester NHS Foundation Trust [...]
    1. University Hospital of South Manchester NHS Foundation Trust
    2. University of Manchester
    Full Title: Randomised Controlled Trial of Lapatinib (A Her1/2 Tyrosine Kinase Inhibitor) on Epithelial Proliferation and Apoptosis in Ductal Cancer in Situ.
    Medical condition: Women with a core biopsy diagnosis of histologically proven Her2 positive DCIS (or DCIS and invasive cancer). Women undergoing re-excision of DCIS will be eligible provided residual DCIS is presen...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065430 HER-2 positive breast cancer LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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