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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 422 of 2,219.
    EudraCT Number: 2006-002018-36 Sponsor Protocol Number: 1200.10 Start Date*: 2006-10-31
    Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG
    Full Title: An open label phase II trial to assess the efficacy and safety of a once daily oral dose of 50 mg BIBW 2992 in two cohorts of patients with HER2-negative metastatic breast cancer after failure of...
    Medical condition: HER2-negative metastatic breast cancer after failure of no more than three chemotherapy regimen in two cohorts of patients; Two Cohorts: Cohort A: Triple negative metastatic breast cancer, i.e. HER...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10027475 Metastatic breast cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Prematurely Ended) BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-006714-14 Sponsor Protocol Number: Tranexamsyra vid kirurgi för avance Start Date*: 2007-12-18
    Sponsor Name:Kvinnokliniken i Östergötland
    Full Title: Tranexamsyra (Cyklokapron®) vid kirurgi för avancerad ovarialcancer - en prospektiv randomiserad dubbelblind studie.
    Medical condition: Bleeding volume in primary surgery for advanced ovarian cancer
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002250-21 Sponsor Protocol Number: 044(D)SC04158 Start Date*: 2005-05-31
    Sponsor Name:ANGELINI
    Full Title: EVALUATION OF ANTALGIC EFFECT AND TOLERABILITY OF A NEW PARACETAMOL SYRUP DOSAGE IN PHARINGOTONSILLYTIS IN PEDIATRY. DOUBLE-BLIND VS PLACEBO STUDY, CONTROLLED VS KETOPROFEN LYSINA SALT.
    Medical condition: ANTALGIC EFFECT AND TOLERABILITY OF A NEW DOSAGE OF PARACETAMOL SYRUP IN PHARINGOTONSILLYTIS IN PEDIATRY
    Disease: Version SOC Term Classification Code Term Level
    6.1 10034835 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-004909-16 Sponsor Protocol Number: D1447C00134 Start Date*: 2005-05-03
    Sponsor Name:AstraZeneca AB
    Full Title: An International, Multi-centre, Double-blind, Randomised, Parallel-group, Placebo-controlled, Phase III study of the Efficacy and Safety of Quetiapine Fumarate (Seroquel™, single oral 300 mg or 600...
    Medical condition: Depressive episodes in bipolar disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001701-26 Sponsor Protocol Number: C-III-001 Start Date*: 2006-02-23
    Sponsor Name:CESAR Central European Society for
    Full Title: First- Line Treatment of Postmenopausal Patients with Endocrine Responsive Metastatic Breast Cancer. A Randomized, Multicenter Study Comparing Letrozole Combined with Standard Chemotherapy Vs Letro...
    Medical condition: hormone-receptor-positive metastatic breast cancer
    Disease: Version SOC Term Classification Code Term Level
    8.0 10055113 PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: AT (Completed) CZ (Prematurely Ended) HU (Prematurely Ended) SI (Prematurely Ended) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-001705-26 Sponsor Protocol Number: CYD-GER-0401 Start Date*: 2005-09-21
    Sponsor Name:Spirig Pharma AG
    Full Title: Efficacy and safety of topically applied cyclodextrin gel (Spirig Pharma) in the treatment of recurrent genital herpes simplex virus infections: a randomised, double-blind, placebo-controlled, mult...
    Medical condition: Genito-anal herpes simplex infections
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001471-37 Sponsor Protocol Number: B4Z-SB-LYDW Start Date*: 2006-10-31
    Sponsor Name:Lilly Deutschland GmbH, Teichweg 3, 35396 Gießen
    Full Title: A Randomized, Double-Blind Comparison of Atomoxetine versus Placebo in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder and Comorbid Oppositional Defiant Disorder
    Medical condition: Children and adolescents with ADHD (Attention-Deficit/Hyperactivity Disorder) and comorbid ODD (Oppositional Defiant Disorder).
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001487-23 Sponsor Protocol Number: TPU-SL-EU05-02 Start Date*: 2006-06-05
    Sponsor Name:Teikoku Pharma USA, Inc.
    Full Title: A Double Blind Randomized Controlled Study of the Effiacy and Safety of Topical Sterile 5% Lidocaine Patch in the Treatment of Postoperative Pain Due to Plastic Surgery of the Breast
    Medical condition: Postoperative Pain Due to the Plastic Surgery of the Breast
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: LV (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-006163-31 Sponsor Protocol Number: Hx-CD20-406 Start Date*: 2006-05-16
    Sponsor Name:Genmab A/S
    Full Title: A single-arm, international, multi-center trial of HuMax-CD20, a fully human monoclonal anti-CD20 antibody, in patients with B-cell Chronic Lymphocytic Leukemia who have failed fludarabine and alem...
    Medical condition: B-cell Chronic Lymphocytic Leukemia
    Disease: Version SOC Term Classification Code Term Level
    7.0 10008959 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) DE (Completed) CZ (Completed) DK (Completed) ES (Completed) NL (Prematurely Ended) IT (Completed) BE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-000584-42 Sponsor Protocol Number: FH1/08 Start Date*: 2008-08-06
    Sponsor Name:Universität Rostock, für diese handelnd Universitätsklinikum
    Full Title: Effekte von Zuclopenthixol auf aggressives Verhalten bei Kindern und Jugendlichen mit einer geistigen oder Lernbehinderung (unterdurchschnittlichen Intelligenz)
    Medical condition: Aggressive Verhaltensstörungen bei intelligenzgeminderten Kindern und Jugendlichen
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001490 Aggressive behaviour LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006291-38 Sponsor Protocol Number: 06-010 Start Date*: 2007-10-02
    Sponsor Name:Jazz Pharmaceuticals, Inc.
    Full Title: A Long-Term, Open-Label Safety and Efficacy Study of Xyrem (sodium oxybate) in Subjects with Fibromyalgia
    Medical condition: Fibromyalgia
    Disease: Version SOC Term Classification Code Term Level
    8.1 10048439 Fibromyalgia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) FR (Ongoing) NL (Completed) PL (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005336-24 Sponsor Protocol Number: P060216 Start Date*: 2007-11-16
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Réduction de la prématurité spontanée : Impact d'un traitement antibiotique (JOSAMYCINE) en cas de PCR positive pour Ureaplasma spp. et/ou Mycoplasma hominis dans le liquide amniotique
    Medical condition: Accouchement prématuré d'origine infectieuse.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005349-13 Sponsor Protocol Number: MC/PR/033011/005/06 Start Date*: 2007-03-27
    Sponsor Name:CHIESI
    Full Title: PROSPECTIVE, RANDOMIZED, OPEN-LABEL, MULTICENTRE,ACTIVE DRUG CONTROLLED, PARALLEL GROUP DESIGN CLINICAL TRIAL OF THE EFFICACY AND SAFETY OF BECLOMETHASONE DIPROPIONATE 400 MCG FORMOTEROL 24 MCG ...
    Medical condition: ASTHMA
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed) ES (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2006-000074-79 Sponsor Protocol Number: 20050210 Start Date*: 2006-05-19
    Sponsor Name:Amgen Ltd
    Full Title: A Multicenter, Single Arm Study Evaluating The Extension From Weekly To Once Every Other Week Darbepoetin Alfa Administration In Subjects With Chronic Kidney Disease Receiving Dialysis.
    Medical condition: Subjects With Chronic Kidney Disease (CKD) Receiving Dialysis
    Disease: Version SOC Term Classification Code Term Level
    7.0 10049105 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-000091-32 Sponsor Protocol Number: 20050225 Start Date*: 2006-10-25
    Sponsor Name:Amgen Inc.
    Full Title: A Randomized Phase 2 Trial of Double- Blind, Placebo Controlled AMG 706 in Combination with Paclitaxel, or Open- Label Bevacizumab in Combination with Paclitaxel, as First Line Therapy in Women wit...
    Medical condition: HER2 Negative Locally Recurrent or Metastatic Breast Cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10027475 Metastatic breast cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IE (Prematurely Ended) ES (Completed) DE (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2007-005082-34 Sponsor Protocol Number: A2620383 Start Date*: 2007-12-14
    Sponsor Name:GlaxoSmithKline Consumer Healthcare
    Full Title: A Proof of Principle Study to Investigate the Efficacy of a Medical Device and Topical Analgesic Combination for the Treatment of Pain and Performance Related Function in Osteoarthritis
    Medical condition: To compare the efficacy of 72 hours (hrs) treatment of topical diclofenac plus a heat patch with 72 hrs treatment of topical diclofenac plus a placebo patch on the primary endpoint of mobility in p...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-006555-12 Sponsor Protocol Number: CHU-PROMOTEUR 2006-08 Start Date*: 2007-05-02
    Sponsor Name:CHU Angers
    Full Title: Étude de phase II, multicentrique, en ouvert, évaluant le dasatinib chez les patients atteints de leucémie aiguë myéloblastique (LAM) à core binding factors (CBF) résistants à la chimiothérapie con...
    Medical condition: évaluant le dasatinib chez les patients atteints de leucémie aiguë myéloblastique (LAM) à core binding factors (CBF) résistants à la chimiothérapie conventionnelle ou en rechute moléculaire.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006562-42 Sponsor Protocol Number: RD-5103-007-06 Start Date*: 2008-02-21
    Sponsor Name:Derby Hospitals NHS Foundation Trust
    Full Title: An Observational and Exploratory Study to determine the effect of anti TNF Biologic Treatment in Rheumatoid Cachexia
    Medical condition: Cachexia in patients with Rheumatoid arthritis.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-006563-23 Sponsor Protocol Number: CMVfluvaccinees Start Date*: 2007-02-07
    Sponsor Name:Health Protection Agency
    Full Title: A Phase IV, single group study to evaluate the immune response to licensed seasonal influenza vaccine and relationship of this to cytomegalovirus-associated immunosenescence in UK older adults aged...
    Medical condition: The vaccine is designed to provide protection against circulating influenza and is being used in the UK influnza immunisation programme 2006-7
    Disease: Version SOC Term Classification Code Term Level
    8.1 10022000 Influenza LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-003696-12 Sponsor Protocol Number: 109MS301 Start Date*: 2007-03-02
    Sponsor Name:Biogen Idec Ltd.
    Full Title: A Randomized, Multicenter, Double-Blind, Placebo-Controlled, Dose-Comparison Study to Determine the Efficacy and Safety of BG00012 in Subjects with Relapsing-Remitting Multiple Sclerosis
    Medical condition: Relapsing-Remitting Multiple Sclerosis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10063399 Relapsing-remitting multiple sclerosis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed) SK (Completed) DE (Completed) CZ (Completed) AT (Completed) SE (Prematurely Ended) NL (Completed) GR (Completed) IT (Completed) BG (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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