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Clinical trials for Musculoskeletal diseases

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,431 result(s) found for: Musculoskeletal diseases. Displaying page 5 of 72.
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    EudraCT Number: 2011-002212-81 Sponsor Protocol Number: LIDOCAINCRPS Start Date*: 2011-11-09
    Sponsor Name:Klinik für Physikalische Medizin und Rehabilitation, Medizinische Universität Wien
    Full Title: Efficacy of Lidocaine medicated plaster in patients with CRPS: a pilot-study
    Medical condition: Complex Regional Pain Syndrome - CRPS lasting longer than 6 month
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-016482-28 Sponsor Protocol Number: SUNIMUD Start Date*: 2010-06-25
    Sponsor Name:Charite Universitätsmedizin Berlin
    Full Title: SUNIMUD - Sunphenon EGCg (Epigallocatechin-Gallate) in Duchenne Muscular Dystrophy
    Medical condition: Duchenne Muscular Dystrophy
    Disease:
    Population Age: Children, Under 18 Gender: Male
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-001267-24 Sponsor Protocol Number: UCA-12-EC/21/ALO Start Date*: 2022-06-24
    Sponsor Name:Arthroscopic Surgery Unit
    Full Title: Pilot study to evaluate intra-articular infiltrations of allogeneic Platelet Rich Plasma (PRP) for the treatment of knee osteoarthritis.
    Medical condition: Knee osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001669-16 Sponsor Protocol Number: 80-83600-98-3143 Start Date*: 2015-12-21
    Sponsor Name:Erasmus MC
    Full Title: Duloxetine for chronic osteoarthritis pain; an important alternative?
    Medical condition: osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-002298-20 Sponsor Protocol Number: CHD046-17 Start Date*: 2018-01-23
    Sponsor Name:Centre Hospitalier Départemental Vendée
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10062893 Rhizarthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2019-004704-35 Sponsor Protocol Number: BTX1-myalgia_pain Start Date*: 2020-05-18
    Sponsor Name:Region Örebro
    Full Title: Masseter myofascial pain relief following an intra-muscular injection with botulinum toxin type A. A randomized double-blind controlled multicenter pilot study.
    Medical condition: Myalgia of jaw muscle
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2020-000638-17 Sponsor Protocol Number: 44107 Start Date*: 2021-03-30
    Sponsor Name:Oslo University Hospital
    Full Title: ZOLEDRONATE EARLY TO HIP FRACTURE PATIENTS – SAFE AND EFFECTIVE? A DOUBLE-BLINDED RANDOMIZED CONTROLLED TREATMENT STRATEGY TRIAL ON ZOLEDRONATE IN HIP FRACTURE PATIENTS THE ZEBRA TRIAL
    Medical condition: Osteoporosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-001888-51 Sponsor Protocol Number: 27109640 Start Date*: 2011-09-12
    Sponsor Name:Inpharm
    Full Title:
    Medical condition: low back pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001912-31 Sponsor Protocol Number: 124/05/16 Start Date*: 2019-12-09
    Sponsor Name:UNIVERSITY MEDICAL CENTRE LJUBLJANA
    Full Title: Treatment of headache attributed to temporomandibular disorder with a flat plane occlusal splint and injections of botulinum toxin
    Medical condition: Headache attributed to temporomandibular disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-005547-23 Sponsor Protocol Number: 12217 Start Date*: 2021-07-22
    Sponsor Name:AZ Delta vzw
    Full Title: Management of Popeye sign with botulinum toxin after tenotomy of the long head of the biceps tendon: a double-blinded randomized controlled trial
    Medical condition: Popeye sign or cramping pain after shoulder artroscopy with biceps tenotomy
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004318-27 Sponsor Protocol Number: stressfrakturogbisfosfonat Start Date*: 2016-08-31
    Sponsor Name:Oslo University Hospital
    Full Title: Intravenous bisphosphonate in stress fracture treatment -A randomised controlled double blinded multicenter trial
    Medical condition: Stress fractures in the foot
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-002758-25 Sponsor Protocol Number: NL2020-01 Start Date*: 2024-01-02
    Sponsor Name:Reade Jan van Breemen Instituut
    Full Title: Treatment of severe gout patients with rasburicase
    Medical condition: Tophaceous gout
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000173-39 Sponsor Protocol Number: Kin-Net-2013-33-Ger Start Date*: 2014-12-08
    Sponsor Name:Jan van Breemen Research Institute Reade and VU University Medical Centre
    Full Title: The effect of IL-1 inhibition by anakinra in acute gout - A proof of concept study-
    Medical condition: Gout
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-000501-26 Sponsor Protocol Number: NanofatTMJ Start Date*: 2022-08-24
    Sponsor Name:University of Tartu Institute of Dentistry
    Full Title: Effect of non-enriched grafting of emulsified adipose tissue in patients with temporomandibular joint osteoarthritis.
    Medical condition: Temporomandibular osteoarthritis.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: EE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-002599-15 Sponsor Protocol Number: 21709298 Start Date*: 2017-11-07
    Sponsor Name:Aarhus University
    Full Title: Effect of pyridostigmine (Mestinon®) on muscle strength in Myasthenia Gravis.
    Medical condition: Myasthenia Gravis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10071942 Myasthenia gravis and related conditions HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-000725-69 Sponsor Protocol Number: Z7202L03 Start Date*: 2011-06-30
    Sponsor Name:Zambon S.p.A.
    Full Title: Efficacy, tolerability and safety of Z7202, a once daily diclofenac diethylamine medicated plaster in the local treatment of painful conditions. Multi-centre, multinational, placebo- controlled, do...
    Medical condition: Localised painful conditions
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10068757 Musculoskeletal and connective tissue pain and discomfort HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) LT (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2019-003742-32 Sponsor Protocol Number: N/A Start Date*: 2020-01-17
    Sponsor Name:University Hospitals Plymouth NHS Trust
    Full Title: The Soft Tissue Injection of Corticosteroid And Local anaesthetic Study - A Single site, non-inferiority randomised control trial evaluating pain after soft tissue corticosteroid injections with an...
    Medical condition: Trigger finger De Quervains tenosynovitis Carpal tunnel syndrome
    Disease: Version SOC Term Classification Code Term Level
    21.0 10028395 - Musculoskeletal and connective tissue disorders 10044654 Trigger finger PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-022794-34 Sponsor Protocol Number: 862-P-201 Start Date*: 2011-03-04
    Sponsor Name:Novartis Consumer Health
    Full Title: A randomized, double-blind, placebo-controlled, multi-center parallel group phase IV study to evaluate the efficacy and safety of Voltaren® Schmerzgel 1.16% gel in subjects with acute neck pain
    Medical condition: Acute neck pain, present for at least 12 hours. An acute condition is defined as pain shorter than 3 months [CPMP, 2002]. Neck pain is defined as stiffness and/or pain felt dorsally in the cervical...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10028836 Neck pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002458-21 Sponsor Protocol Number: MK8259-012-00 Start Date*: 2012-07-23
    Sponsor Name:MERCK SHARP & DOHME B.V.
    Full Title: Open-label, Phase 4 Study, investigating the Incidence of Extra-Articular Manifestations in Subjects with Ankylosing Spondylitis treated with Golimumab
    Medical condition: Ankylosing Spondylitis (Bechterew disease)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10002557 Ankylosing spondylitis and other inflammatory spondylopathies LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2008-005365-61 Sponsor Protocol Number: ACCOST Start Date*: 2010-01-20
    Sponsor Name:Med. Fakultaet der Friedrich-Alexander Universitaet Erlangen-Nuernberg
    Full Title: A PHASE 2, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP, EFFICACY STUDY OF APREMILAST (CC-10004) IN SUBJECTS WITH EROSIVE HAND OSTEOARTHRITIS
    Medical condition: Erosive osteoarthritis of the hand (EHOA)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10019115 Hand osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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