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Clinical trials for Surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    5,833 result(s) found for: Surgery. Displaying page 5 of 292.
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    EudraCT Number: 2016-001584-36 Sponsor Protocol Number: 2014-03-11 Start Date*: 2016-06-01
    Sponsor Name:Universitetssjukhuset Örebro
    Full Title: Is high oxygen concentration a riskfactor for postoperative complications? A prospective, randomized, singel blinded study in elderly patients undergoing vascular surgery
    Medical condition: Elective vascular surgery (peripheral vascular and aortic surgery)
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000516-42 Sponsor Protocol Number: CLX003-IMP-2-170121 Start Date*: 2018-03-20
    Sponsor Name:Cell Therapy Ltd (trading as Celixir)
    Full Title: A Phase IIB, Randomised, Double-Blinded, Placebo-Controlled Study of the Efficacy and Safety of Intramyocardial Injection of Allogeneic Human Immunomodulatory Progenitor (iMP) cells in Patients Und...
    Medical condition: Ischaemic heart disease post MI
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10048858 Ischaemic cardiomyopathy PT
    20.0 10007541 - Cardiac disorders 10023024 Ischaemic heart disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-001505-90 Sponsor Protocol Number: 18CH049 Start Date*: 2018-10-01
    Sponsor Name:CHU de Saint Etienne
    Full Title: Decolonization of patients carrying S. aureus before cardiac surgery: study of the risk factors associated with failure
    Medical condition: Decolonization of S. aureus nasal carriers before cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10075981 Staphylococcus aureus infection LLT
    20.0 100000004865 10048935 Open heart surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000135-40 Sponsor Protocol Number: 260585 Start Date*: 2016-05-12
    Sponsor Name:Zealand University Hospital, Department of Surgery
    Full Title: Endoscopic assisted electrochemotherapy in addition to neoadjuvant treatment of locally advanced rectal cancer: a randomized clinical phase II trial.
    Medical condition: Locally advanced rectal cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010033 Colorectal cancer stage II PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010034 Colorectal cancer stage III PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010023 Colorectal neoplasms malignant HLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-002618-38 Sponsor Protocol Number: AnesBar01 Start Date*: 2013-10-15
    Sponsor Name:
    Full Title: Does preperitoneal local anesthesia in laparoscopic gastric bypass surgery reduce postoperative pain and opioid consumption?
    Medical condition: Postoperative pain
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004863 10054711 Postoperative pain LLT
    16.0 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2019-001086-32 Sponsor Protocol Number: 19-001_AMG Start Date*: 2020-01-02
    Sponsor Name:RWTH Aachen University represented by the Rector himself, represented by the Dean of the Medical Faculty
    Full Title: ADVANCE-CSX Pilot – Antioxidant Treatment with Vitamin C in Cardiac Surgery Patients – a Clinical Pilot Study
    Medical condition: Patients undergoing high-risk open-heart surgery with the use of cardiopulmonary bypass (CPB)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-005090-20 Sponsor Protocol Number: FADOI.01.2016 Start Date*: 2018-05-17
    Sponsor Name:FONDAZIONE FADOI
    Full Title: Rivaroxaban or placebo for extended antithrombotic prophylaxis after laparoscopic surgery for colorectal cancer: a randomized, double blind, placebo-controlled study. THE PRO-LAPS STUDY II
    Medical condition: Prevention of venous thromboembolism after laparoscopic surgery for colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10067650 Pulmonary embolism prophylaxis LLT
    21.1 100000004865 10012108 Deep venous thrombosis prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-001027-33 Sponsor Protocol Number: PAFIBAR1.0 Start Date*: 2023-06-07
    Sponsor Name:FIMABIS
    Full Title: Evaluation of the effect of Opioid-Free Anesthesia on oxygenation in bariatric surgery
    Medical condition: Bariatric surgery
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10068900 Bariatric surgery LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002217-19 Sponsor Protocol Number: 232100-0024 Start Date*: 2012-12-13
    Sponsor Name:Dept of Surgery [...]
    1. Dept of Surgery
    2. Landstinget i Uppsala
    Full Title: Postoperative treatment with Vitamin D for patients with a history of Bariatric Surgery in C and U County.
    Medical condition: Hypovitaminosis D after bariatric surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015799-92 Sponsor Protocol Number: FER-SURG02-Pilot Start Date*: 2009-12-02
    Sponsor Name:Universitätspital Zürich Anästhesie
    Full Title: Intravenous ferric carboxymaltose (Ferinject®) with or without Erythropoietin for the correction of preoperative anaemia in patients undergoing orthopaedic surgery
    Medical condition: • To evaluate the effect of the administration of ferric carboxymaltose (Ferinject®) with or without erythropoietin vs. no treatment (standard therapy) on the preoperative anaemia status in patient...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001487-23 Sponsor Protocol Number: TPU-SL-EU05-02 Start Date*: 2006-06-05
    Sponsor Name:Teikoku Pharma USA, Inc.
    Full Title: A Double Blind Randomized Controlled Study of the Effiacy and Safety of Topical Sterile 5% Lidocaine Patch in the Treatment of Postoperative Pain Due to Plastic Surgery of the Breast
    Medical condition: Postoperative Pain Due to the Plastic Surgery of the Breast
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: LV (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-015086-31 Sponsor Protocol Number: Ten03 Start Date*: 2010-03-16
    Sponsor Name:Bio Products Laboratory Limited
    Full Title: Ten03: A Phase III Open, Multicentre Study to Investigate the Safety and Efficacy of BPL’s High Purity Factor X in the treatment of the Factor X Deficient Subjects Undergoing Surgery
    Medical condition: Factor X Deficiency
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-012372-27 Sponsor Protocol Number: 200901 Start Date*: 2009-09-17
    Sponsor Name:LUMC
    Full Title: The Sevoflurane study, understanding the effects of Sevoflurane to improve safety and outcome of cardiac surgery
    Medical condition: myocardial ischemia reperfusion injury during cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003164-62 Sponsor Protocol Number: 1976 Start Date*: 2007-01-22
    Sponsor Name:University Hospital Birmingham
    Full Title: Metabolic Support with Perhexilene to Protect Myocardium undergoing Coronary Artery Surgery
    Medical condition: Patients undergoing coronary artery bypass surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004964-39 Sponsor Protocol Number: 51503 Start Date*: 2015-05-22
    Sponsor Name:Sint Antonius Ziekenhuis
    Full Title: Clonidine as Additive for Locoregional Postoperative Analgesia in Foot and Anckle Surgery
    Medical condition: Postoperative pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001551-22 Sponsor Protocol Number: RECIPE2014 Start Date*: 2014-12-18
    Sponsor Name:Charité Universitätsmedizin
    Full Title: Reduction of postoperative wound infections by antiseptica
    Medical condition: Laparotomy wound after closure of the fascia after visceral surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-000588-41 Sponsor Protocol Number: TRANEX-URO Start Date*: 2008-02-26
    Sponsor Name:OSPEDALE S. RAFFAELE
    Full Title: Tranexamic acid efficacy reducing surgery bleding in patients undergoing surgery for complete prostatectomy.
    Medical condition: patients undergoing prostatic radical surgery for prostatic cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038961 Retro-pubic prostatectomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-004506-21 Sponsor Protocol Number: 21/2 Start Date*: 2021-11-30
    Sponsor Name:Hospital Universitario Fundación Alcorcón
    Full Title: ERECTOR SPINAE PLANE CATHETERS IN SCOLIOSIS SURGERY
    Medical condition: Postoperative pain following scoliosis surgery
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001944-13 Sponsor Protocol Number: ZAA15CPP Start Date*: 2016-07-27
    Sponsor Name:Zaans Medisch Centrum
    Full Title: Chloroprocaine vs prilocaine for spinal anaesthesia in day-case surgery: a double-blind randomized trial
    Medical condition: Patients scheduled for ambulatory knee arthroscopy surgery receive one of the two spinal anaesthetics
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2021-005452-11 Sponsor Protocol Number: - Start Date*: 2022-01-21
    Sponsor Name:Medizinische Universität Innsbruck
    Full Title: Influence of the PECS II block on postoperative pain and opioid demand in patients undergoing minimal invasive cardiac surgery
    Medical condition: Patients scheduled for minimal invasive cardia surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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