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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 57 of 2,219.
    EudraCT Number: 2006-003501-71 Sponsor Protocol Number: CERL080AIT09 Start Date*: 2006-11-14
    Sponsor Name:NOVARTIS FARMA
    Full Title: Studio multicentrico controllato, randomizzato, per gruppi paralleli, per valutare l’efficacia e la tollerabilita' di Myfortic a dose piena, insieme a ciclosporina in microemulsione a dose ridotta,...
    Medical condition: chronic rejection after kidney transplant
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023439 Kidney transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-003502-26 Sponsor Protocol Number: ESA-1 Start Date*: 2006-12-14
    Sponsor Name:Barts and the London NHS Trust
    Full Title: A randomised control trial of the use of Epoetin Beta in the treatment of Post Transplant Anaemia
    Medical condition: Post Transplant Anaemia
    Disease: Version SOC Term Classification Code Term Level
    8.1 10002071 Anaemia NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-003512-22 Sponsor Protocol Number: 0869-130 Start Date*: 2006-11-23
    Sponsor Name:Laboratoires Merck Sharp & Dohme-Chibret
    Full Title: A Randomized, Double-Blind, Parallel-Group Study Conducted Under In-House Blinding Conditions to Determine the Efficacy and Tolerability of Aprepitant for the Prevention of Chemotherapy-Induced Nau...
    Medical condition: Chemotherapy-induced Nausea and Vomitting
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004270-25 Sponsor Protocol Number: A3191173 Start Date*: 2005-12-09
    Sponsor Name:Pfizer Ltd
    Full Title: Double-blind, parallel-group, randomized, study of the efficacy and safety of continuous use of celecoxib vs the “usual use” of celecoxib in the treatment of subjects with chronicosteoarthritis of ...
    Medical condition: Osteoarthritis of knee or hip joint
    Disease: Version SOC Term Classification Code Term Level
    8.1 10031161 VTc
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001526-27 Sponsor Protocol Number: STH14707 Start Date*: 2007-06-19
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: ANZAC: A Randomised Phase II Feasibility Study Investigating The Biological Effects of the Addition of Zoledronic Acid To Neoadjuvant Comnination Chemotherapy On Invasive Breast Cancer
    Medical condition: Breast cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006187 Breast cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-002362-37 Sponsor Protocol Number: GlaxoSmithKline, B2C101762 Start Date*: 2004-12-22
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A multicentre, randomised, double-blind, placebo-controlled, dose ascending, four way crossover study to examine efficacy (FEV1),safety, tolerability, pharmacodynamics and pharmacokinetics of sing...
    Medical condition: GW642444 is a new potent and selective inhaled beta-2-receptor agonist, which is being developed for once daily treatment of asthma and COPD.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2004-002370-39 Sponsor Protocol Number: D9614C00097 Start Date*: 2004-12-02
    Sponsor Name:ASTRAZENECA
    Full Title: A Phase III, Multicentre, Randomized, Double-blind Parallel-group Study to Evaluate the Safety and Clinical Outcome of Once Daily Esomeprazole for the Treatment of Gastroesophageal Reflux Disease ...
    Medical condition: Gastroesophageal Reflux Disease GERD
    Disease: Version SOC Term Classification Code Term Level
    6.1 10017885 PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2004-004388-31 Sponsor Protocol Number: 291-412 Start Date*: 2005-06-03
    Sponsor Name:PDL BioPharma, Inc
    Full Title: A Phase IIa, Open-label Study of Visilizumab in Patients with Moderate-to-Severe Inflammatory, Nonstricturing, Nonpenetrating Forms of Crohn’s Disease
    Medical condition: Moderate-to-severe inflammatory, nonstricturing, nonpenetrating Crohn’s disease (CD).
    Disease: Version SOC Term Classification Code Term Level
    7.1 10011401 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004394-28 Sponsor Protocol Number: 04\Q0704\38 Start Date*: 2005-01-07
    Sponsor Name:Guy's & St Thomas' NHS Foundation Trust
    Full Title: The use of local anasthesia for pain control in children undergoing dental general anaesthesia
    Medical condition: Patients requiring dental restorations of decayed teeth and dental extractions of teeth with dental abscesses.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005406-24 Sponsor Protocol Number: IIL-FOLL05 Start Date*: 2006-01-30
    Sponsor Name:FONDAZIONE ITALIANA LINFOMI ONLUS
    Full Title: Phase III multicentric IIL study, three randomized arms (R-CVP vs R-CHOP vs R-FM),for treatment of patients with stage II-IV follicular lymphoma
    Medical condition: Stage II-IV Follicular Lymphoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10016897 Follicle centre lymphoma diffuse small cell lymphoma recurrent PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005428-15 Sponsor Protocol Number: AGO/2005/003 Start Date*: 2006-01-30
    Sponsor Name:University Hospital Ghent
    Full Title: Vergelijkende studie tussen Propofol en Sevoflurane: sedatie en hemodynamiek postoperatief na electieve CABG (Coronair bypass chirurgie)
    Medical condition: postoperatieve anesthesie zorgen na electieve CABG
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005713-35 Sponsor Protocol Number: RPE 04 Start Date*: 2007-03-20
    Sponsor Name:Curalogic A/S
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PARALLEL GROUP, PLACEBO-CONTROLLED STUDY TO ASSESS THE EFFICACY AND SAFETY OF ORAL MICROENCAPSULATED RAGWEED POLLEN EXTRACT ADMINISTERED PRIOR TO AND DURING THE RAGWEED ...
    Medical condition: Treatment of seasonal allergic rhinitis to ragweed pollen.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005727-41 Sponsor Protocol Number: 6018-PG-PSC-148 Start Date*: 2007-07-26
    Sponsor Name:Laboratorios LETI S.L.
    Full Title: Ensayo clínico, multicéntrico, aleatorizado, doble ciego controlado con placebo, de inmunoterapia subcutánea con extracto despigmentado y polimerizado de polen de Olea europaea en pacientes con hip...
    Medical condition: Asma de intensidad leve o moderada y/o rinoconjuntivitis inducidas por hipersensibilidad frente al polen del olivo.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003553 Asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002168-24 Sponsor Protocol Number: IEO S301/306 Start Date*: 2006-10-18
    Sponsor Name:ISTITUTO EUROPEO DI ONCOLOGIA
    Full Title: O6-alkylguanine-DNA-alkyltransferase modulation study Fotemustine plus Temozolomide phase I/II .
    Medical condition: metastatic stage III, IV not operable melanoma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10027480 Metastatic malignant melanoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-002187-25 Sponsor Protocol Number: Accrobat Start Date*: 2007-01-26
    Sponsor Name:Radiumhemmet, Karolinska University Hospital
    Full Title: A multicenter, open label, non-randomised phase II study with induction chemotherapy with Cisplatin and 5-fluorouracil as combined with accelerated radiotherapy and Erbitux for locally advanced unr...
    Medical condition: Patient with locally advanced non-resectable squamous cell carcinoma of the head and neck stage III or IV, oral, oropharyngeal, laryngeal or hypopharyngeal cancer, non-resectable.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003132-29 Sponsor Protocol Number: KF10004/03 Start Date*: 2007-01-10
    Sponsor Name:Grünenthal GmbH
    Full Title: Safety and efficacy of lidocaine 5% medicated plaster in comparison with pregabalin in postherpetic neuralgia and diabetic polyneuropathic pain
    Medical condition: postherpetic neuralgia and painful diabetic polyneuropathy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) SI (Completed) BE (Completed) CZ (Completed) AT (Completed) SE (Completed) DE (Completed) PT (Completed) IT (Completed) GB (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2005-003570-22 Sponsor Protocol Number: MNB3 (C60P1) Start Date*: 2005-09-29
    Sponsor Name:Health Protection Agency
    Full Title: A PHASE II, OPEN LABEL, RANDOMISED, SINGLE CENTRE STUDY TO EVALUATE THE SAFETY, REACTOGENICITY AND IMMUNOGENICITY OF THREE OR FOUR DOSES OF MENINGOCOCCAL SEROGROUP B OUTER MEMBRANE VESICLE (OMV) VA...
    Medical condition: Prevention of invasive disease caused by N. meningitidis serogroup B
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002330-38 Sponsor Protocol Number: RituxiCAN-C4 Start Date*: 2006-11-22
    Sponsor Name:King's College London
    Full Title: Randomised Trial of Anti-CD20 in C4d+ Chronic Allograft Nephropathy
    Medical condition: Renal Transplant Rejection - chronic
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021428 - Immune system disorders 10023439 Kidney transplant rejection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-002335-24 Sponsor Protocol Number: 13362B Start Date*: 2006-11-23
    Sponsor Name:University of Chicago
    Full Title: A Phase III Randomized Trial of Docetaxel Based Induction Chemotherapy in Patients with N2/N3 Locally Advanced Head and Neck Cancer Estudio de fase III randomizado de una quimioterapia de inducción...
    Medical condition: Phase III trial of induction therapy with docetaxel followed by chemoradiotherapy versus chemoradiotherapy alone in patients with nodal stage N2 or N3 head and neck cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002342-11 Sponsor Protocol Number: D1449L00033 Start Date*: 2007-04-19
    Sponsor Name:Klinikum Fulda gAG
    Full Title: Multicenter study of neurotransmitters and neuropeptides in schizophrenia: A multidisciplinary study of biological, pharmacokinetic, receptor occupancy and clinical relationships in patients suffer...
    Medical condition: Patients have to fulfill the diagnostic criteria of a schizophrenia according to DSM-IV.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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