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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,335 result(s) found. Displaying page 57 of 2,217.
    EudraCT Number: 2006-004478-29 Sponsor Protocol Number: ASL606LIOM02 Start Date*: 2006-12-17
    Sponsor Name:G.O.N.O. - GRUPPO ONCOLOGICO NORD OVEST
    Full Title: DOCETAXEL AND PREDNISON IN ASSOCIATION WITH METRONOMIC THERAPY WITH CICLOPHOSPHAMIDE AND CELECOXIN IN HORMONE-REFRACTORY PROSTATIC CANCER PATIENTS : PHASE II CLINICAL TRIAL WITH PHARMACODYNAMIC AND...
    Medical condition: PATIENTS WITH PROSTATIC HORMONE-REFRACTORY CANCER
    Disease: Version SOC Term Classification Code Term Level
    15.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060862 Prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004467-29 Sponsor Protocol Number: Start Date*: 2005-07-27
    Sponsor Name:Craigavon Area Hospital Group Trust
    Full Title: An open label pilot study to evaluate the efficacy and safety of topical tacrolimus 0l1% (Protopic) in the treatment of varicose eczema
    Medical condition: Varicose eczema
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004237-15 Sponsor Protocol Number: RD.03.SPR29057 Start Date*: 2007-03-06
    Sponsor Name:Galderma Research and Development
    Full Title: Comparison of Metvix® PDT with its vehicle in the treatment of photoaged skin
    Medical condition: Male and female subjects aged at least 30 years with a clinical diagnosis of photodamage (a score of at least 4 on the Griffiths photonumeric scale) and presence of mottled hyper-pigmentation on th...
    Disease: Version SOC Term Classification Code Term Level
    9.0 10064131 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-004245-42 Sponsor Protocol Number: 10078 Start Date*: 2006-09-07
    Sponsor Name:University Hospitals of Leicester NHS Trust
    Full Title: PHARMACODYNAMIC STUDY OF ORAL MIRTOSELECT IN PATIENTS WITH SUSPECTED HEPATIC DISEASE
    Medical condition: Patients with operable liver metastases
    Disease: Version SOC Term Classification Code Term Level
    8.1 10024700 Liver metastases LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-004247-29 Sponsor Protocol Number: AMD3100-EU23 Start Date*: 2007-08-22
    Sponsor Name:Genzyme Europe BV
    Full Title: A Multicenter, Randomized, Comparative, Patient-blinded Study to Evaluate the Safety and Efficacy of G-CSF Alone Versus AMD3100 (240 µg/kg) Added to a G-CSF Mobilization Regimen in Adult Patients w...
    Medical condition: Mobilization of stem cells prior to autologous stem cell transplantation in patients with multiple myeloma, non-Hodgkin's lympoma, and Hodgkin's disease.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10029547 Non-Hodgkin's lymphoma LLT
    9.1 10028228 Multiple myeloma LLT
    9.1 10020206 Hodgkin's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004260-31 Sponsor Protocol Number: HUM-05-096 Start Date*: 2007-02-21
    Sponsor Name:UHL NHS Trust
    Full Title: An open label study of humira (adalimumab)in the treatment of patients with severe psoriasis
    Medical condition: Psoriasis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10037153 Psoriasis LLT
    Population Age: Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-004799-35 Sponsor Protocol Number: DRI5349 Start Date*: 2005-05-25
    Sponsor Name:Sanofi-aventis recherche and developpement
    Full Title: Double blind placebo controlled dose ranging study of the efficacy and safety of SSR149744C 100 or 300 mg for the prevention of ventricular arrhythmia-triggered ICD interventions
    Medical condition: Ventricular arrhythmia triggered ICD interventions
    Disease: Version SOC Term Classification Code Term Level
    7.1 10003131 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-004819-29 Sponsor Protocol Number: n.a. Start Date*: 2005-04-12
    Sponsor Name:UNIVERSITA' DEGLI STUDI DI UDINE
    Full Title: Use of Rituximab in the treatment of extensive chronic graft versus host disease after allogenic stem cells transplantation
    Medical condition: Use of Rituximab in the treatment of refractory extensive chronic graft versus host disease after allogenic stem cells transplantation
    Disease: Version SOC Term Classification Code Term Level
    6.1 10048870 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004825-87 Sponsor Protocol Number: R00002 VE 201 Start Date*: 2005-04-22
    Sponsor Name:Pierre Fabre Dermatologie represented by Institut de Recherche Pierre Fabre
    Full Title: Efficacy and safety of 0,1%, 0,5% and 1% TAZAROTENE nail lacquer formulation versus vehicle in nail psoriasis. International, multicenter, double-blind, randomized study of four parallel groups.
    Medical condition: Psoriasis of the skin is frequently accompanied by nail changes: between 10 and 78% of psoriatic patients suffer from changes of the nails. More than 50% of patients with nail psoriasis have pain b...
    Disease: Version SOC Term Classification Code Term Level
    7.1 10028703 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2004-004852-38 Sponsor Protocol Number: MV 17149 - HELPS Start Date*: 2005-04-06
    Sponsor Name:ROCHE
    Full Title: A randomized, open label, multicenter, parallel group study evaluating the efficacy and safety of 135 mcg and 90 mcg of Pegasys given as monotherapy to patients with chronic hepatitis C and end-sta...
    Medical condition: chronic hepatitis C CHC virus infection in patients with end-stage renal disease ESRD undergoing hemodialysis
    Disease: Version SOC Term Classification Code Term Level
    6.1 10019744 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-000097-23 Sponsor Protocol Number: SAM109352 Start Date*: 2007-09-04
    Sponsor Name:GlaxoSmithKline
    Full Title: Rationale for therapy with low dose steroids combined with long-acting beta2-agonists in patients with allergic asthma: redirecting innate immune responses by long-term treatment with high doses of...
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001705 Allergic asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000120-40 Sponsor Protocol Number: 2006/0606 Start Date*: 2007-06-07
    Sponsor Name:Centre Hospitalier Régional et Universitaire
    Full Title: Etude contrôlée comparative en double aveugle de l'effet d'un traitement par le fénofibrate sur l'expression des génes de l'homéostasie du cholestérol, de l'inflammation et de la prolifération cell...
    Medical condition: Patients présentant des lésions athérosclérosiques carotidiennes asymptomatiques diabétiques ou non diabétiques sous statines .
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-002888-88 Sponsor Protocol Number: 027SC05013 Start Date*: 2006-02-22
    Sponsor Name:ANGELINI
    Full Title: A randomised, ciprofloxacin-controlled study of two prulifloxacin regimens in antibiotic prophylaxis for transrectal prostatic biopsy TPB .
    Medical condition: antibiotic prophylaxis for transrectal prostatic biopsy
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-003483-59 Sponsor Protocol Number: CVAL489A2429 Start Date*: 2006-12-18
    Sponsor Name:VU University Medical Centre
    Full Title: PRESERVE TRIAL: Pancreatic beta-cell dysfunction REStorEd by Rosiglitazone and Valsartan Effects; A 52-week randomized controlled factorial study in subjects with impaired fasting glucose and/or im...
    Medical condition: subjects with impaired fasting glucose (IFG; blood glucose > or = 5.6 and < 7 mmol/l) and/or impaired glucose tolerance (IGT; 2-h post-load glucose 7.8-11.1 mmol/l).
    Disease: Version SOC Term Classification Code Term Level
    8.1 10018429 Glucose tolerance impaired LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003495-35 Sponsor Protocol Number: IEO S311/306 Start Date*: 2007-06-05
    Sponsor Name:ISTITUTO EUROPEO DI ONCOLOGIA
    Full Title: PHASE II TRIAL OF BORTEZOMIB (VELCADE) IN COMBINATION WITH CHLORAMBUCIL IN PATIENTS WITH RELAPSED/REFRACTORY WALDENSTROMムS MACROGLOBULINEMIA OR SMALL LYMPHOCYTIC LYMPHOMA. A MULTICENTER STUDY.
    Medical condition: WALDENSTROMムS MACROGLOBULINEMIA OR SMALL LYMPHOCYTIC LYMPHOMA
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003908 B-cell small lymphocytic lymphoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-003501-71 Sponsor Protocol Number: CERL080AIT09 Start Date*: 2006-11-14
    Sponsor Name:NOVARTIS FARMA
    Full Title: Studio multicentrico controllato, randomizzato, per gruppi paralleli, per valutare l’efficacia e la tollerabilita' di Myfortic a dose piena, insieme a ciclosporina in microemulsione a dose ridotta,...
    Medical condition: chronic rejection after kidney transplant
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023439 Kidney transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-003502-26 Sponsor Protocol Number: ESA-1 Start Date*: 2006-12-14
    Sponsor Name:Barts and the London NHS Trust
    Full Title: A randomised control trial of the use of Epoetin Beta in the treatment of Post Transplant Anaemia
    Medical condition: Post Transplant Anaemia
    Disease: Version SOC Term Classification Code Term Level
    8.1 10002071 Anaemia NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-003512-22 Sponsor Protocol Number: 0869-130 Start Date*: 2006-11-23
    Sponsor Name:Laboratoires Merck Sharp & Dohme-Chibret
    Full Title: A Randomized, Double-Blind, Parallel-Group Study Conducted Under In-House Blinding Conditions to Determine the Efficacy and Tolerability of Aprepitant for the Prevention of Chemotherapy-Induced Nau...
    Medical condition: Chemotherapy-induced Nausea and Vomitting
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004270-25 Sponsor Protocol Number: A3191173 Start Date*: 2005-12-09
    Sponsor Name:Pfizer Ltd
    Full Title: Double-blind, parallel-group, randomized, study of the efficacy and safety of continuous use of celecoxib vs the “usual use” of celecoxib in the treatment of subjects with chronicosteoarthritis of ...
    Medical condition: Osteoarthritis of knee or hip joint
    Disease: Version SOC Term Classification Code Term Level
    8.1 10031161 VTc
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001526-27 Sponsor Protocol Number: STH14707 Start Date*: 2007-06-19
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: ANZAC: A Randomised Phase II Feasibility Study Investigating The Biological Effects of the Addition of Zoledronic Acid To Neoadjuvant Comnination Chemotherapy On Invasive Breast Cancer
    Medical condition: Breast cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006187 Breast cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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