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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44358   clinical trials with a EudraCT protocol, of which   7384   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,358 result(s) found. Displaying page 589 of 2,218.
    «« First « Previous 585  586  587  588  589  590  591  592  593  Next» Last»»
    EudraCT Number: 2010-018792-17 Sponsor Protocol Number: KM004EIC Start Date*: 2011-07-04
    Sponsor Name:Kliniken der Stadt Koeln gGmbH, Klinikum Merheim
    Full Title: Single-center, single-armed, open-label, prospective study assessing efficacy and safety of a conversion of kidney allograft recipients suffering from Chronic Allograft Nephropathy (CAN) assessed ...
    Medical condition: This study is designed to assess whether a conversion from a CNI-based therapy to a CNI-free therapy with Certican® and Myfortic® in renal transplant patients with Chronic Allograft Nephropathy (CA...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018794-38 Sponsor Protocol Number: RTXTTP2010 Start Date*: 2010-02-23
    Sponsor Name:FONDAZIONE IRCCS CA` GRANDA OSPEDALE MAGGIORE POLICLINICO DI MILANO
    Full Title: EVALUATION OF CLINICAL RESPONSE TO RITUXIMAB TREATMENT IN PATIENTS WITH ACQUIRED AUTOIMMUNE RECURRENT THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP)
    Medical condition: THROMBOTIC THROMBOCYTOPENIC PURPURA
    Disease: Version SOC Term Classification Code Term Level
    9.1 10037562 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-005007-26 Sponsor Protocol Number: DAM/002/08 Start Date*: 2008-11-04
    Sponsor Name:FARMACEUTICI DAMOR
    Full Title: An open-label, controlled, randomized, prospective, between groups, multicenter clinical trial on the efficacy and safety of Fitostimoline (vaginal cream, vaginal suppositories and vaginal solution...
    Medical condition: Patients with aspecific vaginosis and/or vulvo vaginitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10046953 Vaginitis and vulvovaginitis, unspecified LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005018-39 Sponsor Protocol Number: TDE-DU-201 Start Date*: 2009-03-05
    Sponsor Name:United Therapeutics Corporation
    Full Title: DISTOL-1:Digital Ischaemic Lesions in Scleroderma treated with Oral Treprostinil Diethanolamine: A randomized, double-blind, placebo controlled, multicenter study
    Medical condition: Systemic Sclerosis, scleroderma digital ulcers
    Disease: Version SOC Term Classification Code Term Level
    9.1 10042953 Systemic sclerosis LLT
    9.1 10039710 Scleroderma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005304-16 Sponsor Protocol Number: 292001 Start Date*: 2006-06-09
    Sponsor Name:NV Organon
    Full Title: A randomized, open-label, comparative, multi-center trial to evaluate contraceptive efficacy, cycle control, safety and acceptability of a monophasic combined oral contraceptive (COC) containing 2....
    Medical condition: Hormonal oral contraception in healthy women
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed) SE (Completed) DK (Completed) FI (Completed) BE (Completed) DE (Completed) ES (Completed) CZ (Completed) GB (Completed) IT (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2008-007447-14 Sponsor Protocol Number: 222500 Start Date*: 2009-04-03
    Sponsor Name:UNIVERSITA' DEGLI STUDI DI NAPOLI FEDERICO II
    Full Title: GH-IGF-I status and Multiple Sclerosis: clinical implications (a prevalence study).
    Medical condition: patients with Multiple Sclerosis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10022891 Investigations SOC
    14.1 10014698 - Endocrine disorders 10014698 Endocrine disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003208-68 Sponsor Protocol Number: HCL/P 2007.467/10 Start Date*: 2008-09-11
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Groupe d’Evaluation Français Avastin® versus Lucentis®
    Medical condition: Dégénérescence Maculaire Liée à l’Age (DMLA)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064930 Age-related macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003226-42 Sponsor Protocol Number: 91550 Start Date*: 2008-12-10
    Sponsor Name:Bayer HealthCare AG
    Full Title: A multicenter, randomized, double-blind, active-controlled, parallel group, 2-arm study to investigate the effect of estradiol valerate/dienogest compared to Microgynon on hormone withdrawal associ...
    Medical condition: Hormone withdrawal associated symptoms of headache and pelvic pain suffered by patients receiving LNG containing oral contraception.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030970 Oral contraception LLT
    Population Age: Adults Gender: Female
    Trial protocol: FI (Completed) DE (Completed) ES (Completed) GB (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-011245-55 Sponsor Protocol Number: 09575704 Start Date*: 2009-05-06
    Sponsor Name:Active Biotech Research AB
    Full Title: An Exploratory Study to Evaluate Changes in Disease Activity and Biomarkers During Treatment With ABR-215757 in Patients With Mild Active Systemic Lupus Erythematosus (SLE). Final Protocol dated 20...
    Medical condition: Systemic Lupus Erythematosus (SLE)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2010-020437-12 Sponsor Protocol Number: DT-DP-D2b Start Date*: Information not available in EudraCT
    Sponsor Name:DermaTools Biotech GmbH
    Full Title: A multicentric, double blind, randomized, comparative Phase II b study of the efficacy of a wound healing solution in patients with diabetic foot ulcer
    Medical condition: diabetic foot ulcer
    Disease: Version SOC Term Classification Code Term Level
    12.1 10012664 Diabetic foot ulcer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) LV (Prematurely Ended) LT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-020442-10 Sponsor Protocol Number: MODAt Start Date*: 2010-07-26
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: Efficacy of atazanavir/ritonavir monotherapy as maintenance in patients with viral suppression. Randomized, open label non inferiority trial. (MODAt STUDY)
    Medical condition: HIV infected Patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008922 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-020451-32 Sponsor Protocol Number: AMCmedonc010 Start Date*: 2010-12-10
    Sponsor Name:Academic Medical Center Amsterdam
    Full Title: Pilot study of everolimus in the treatment of advanced malignancies in patients with Peutz-Jeghers syndrome
    Medical condition: Advanced malignancy of any tumor type, not suitable for surgery at the time of study enter in patients with known Peutz-Jeghers disease (with LKB1 mutation).
    Disease: Version SOC Term Classification Code Term Level
    12.1 10034764 Peutz-Jeghers syndrome PT
    12.1 10029111 Neoplasms unspecified malignancy and site unspecified NEC HLT
    12.1 10034764 Peutz-Jeghers syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010967-18 Sponsor Protocol Number: DM-UMCU-01 Start Date*: 2009-11-11
    Sponsor Name:University Medical Centre Utrecht
    Full Title: Effect of adding vildagliptin to start of insulin treatment in combination with metformin in patients with type 2 diabetes
    Medical condition: patients with type 2 diabetes, failing on maximal oral glucose-lowering drugs, starting on insulin therapy in combination with standard metfromin (2 x 850)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012594 Diabetes LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-010982-22 Sponsor Protocol Number: DSC/08/2357/38 Start Date*: 2009-04-20
    Sponsor Name:ITALFARMACO
    Full Title: Phase II study of the histone-deacetylase inhibitor GIVINOSTAT (ITF2357) in combination with hydroxyurea in patients with JAK2V617F positive Polycythemia Vera non-responder to hydroxyurea monotherapy
    Medical condition: Polycythemia Vera
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004851 10018847 Haematological disorders HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-018168-81 Sponsor Protocol Number: EMR-700773-503 Start Date*: 2010-04-16
    Sponsor Name:Merck Serono Norway
    Full Title: ENDURE: A Phase IV, prospective, open-label, uncontrolled, multi-centre cohort trial to assess the responsiveness of subjects with phenylketonuria (PKU) to treatment with Kuvan® 20 mg/kg/day for 28...
    Medical condition: Subjects diagnosed with Phenylketonuria (PKU) (classic or mild PKU, or mild hyperphenylalaninaemia (HPA)).
    Disease: Version SOC Term Classification Code Term Level
    14.1 10010331 - Congenital, familial and genetic disorders 10034873 Phenylketonuria (PKU) LLT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) NO (Ongoing)
    Trial results: View results
    EudraCT Number: 2006-000805-42 Sponsor Protocol Number: MeIn/06/Fro-pp/001 Start Date*: 2007-06-12
    Sponsor Name:Menarini International Operations Luxembourg S.A., Avenue de la Gare, 1611 Luxembourg, Luxembourg
    Full Title: A double-blind, cross-over patient preference study of frovatriptan versus zolmitriptan for the acute treatment of migraine
    Medical condition: Migraine with or without aura according to the IHS criteria
    Disease: Version SOC Term Classification Code Term Level
    8.1 10027599 Migraine LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IE (Completed) DK (Completed) ES (Completed) PT (Completed)
    Trial results: View results
    EudraCT Number: 2008-002986-30 Sponsor Protocol Number: CLBH589B2116 Start Date*: 2010-01-08
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A phase Ib, open-label, multi-center dose-finding study of oral panobinostat (LBH589) in combination with ara-C and mitoxantrone as salvage therapy for refractory or relapsed acute myeloid leukemia
    Medical condition: refractory or relapsed acute myeloid leukemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000886 Acute myeloid leukemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-000072-25 Sponsor Protocol Number: IG402 Start Date*: 2008-08-04
    Sponsor Name:Instituto Grifols S.A.
    Full Title: Estudio prospectivo, simple ciego, de Fase II/III para evaluar la Seguridad y Eficacia del Adhesivo de Fibrina Grifols (FS Grifols) como un Adyuvante a la Hemostasia durante Cirugía Vascular Perifé...
    Medical condition: Adyuvante a la hemostasia en cirugía vascular periférica. Adjunct to hemostasis during peripheral vascular surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-000077-38 Sponsor Protocol Number: CRAD001L2201 Start Date*: 2008-10-09
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A randomized, open label, multi-center phase II study to compare bevacizumab plus RAD001 versus interferon alfa-2a and bevacizumab for the first-line treatment of patients with metastatic clear cel...
    Medical condition: Patients with metastatic clear cell carcinoma of the kidney
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050513 Metastatic renal cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) BE (Prematurely Ended) GB (Prematurely Ended) CZ (Prematurely Ended) HU (Prematurely Ended) ES (Prematurely Ended) DE (Completed) IT (Prematurely Ended) FR (Completed) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-004954-99 Sponsor Protocol Number: BO2 Start Date*: 2008-08-21
    Sponsor Name:Göteborg University, Sect. Psyhiatry and Neurochemistry [...]
    1. Göteborg University, Sect. Psyhiatry and Neurochemistry
    2. Göteborg University, Sect. Psychiatry and Neurochemistry
    Full Title: Does varenicline influence alcohol consumption in alcohol dependent individuals?
    Medical condition: Alcohol dependence Nicotine dependence in alcohol dependent individuals
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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