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Clinical trials for General anesthesia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    368 result(s) found for: General anesthesia. Displaying page 6 of 19.
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    EudraCT Number: 2021-000727-12 Sponsor Protocol Number: RC31/20/0443 Start Date*: 2021-06-28
    Sponsor Name:University Hospital of Toulouse
    Full Title: Quality Assessment of Tracheal intubation without neuromuscular blocking drugs (Propofol+ Remifentanil) in obese patients: Pilot Study
    Medical condition: induction phase of the general anesthesia in obese patients
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002362-39 Sponsor Protocol Number: TALVISUG01 Start Date*: 2013-11-21
    Sponsor Name:Consorci Mar Parc de Parc de Salut de Barcelona (Parc de Salut MAR)
    Full Title: Reducing the dose of sugammadex 50% reverse the neuromuscular blockade of rocuronium effectively after general anesthesia.
    Medical condition: Neuromuscular blockade is induced during general anesthesia, which often does not recover spontaneously, so it is necessary a pharmacological reversal. We believe that sugammadex at lower doses tha...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10057286 Neuromuscular blockade reversal PT
    14.1 10029205 - Nervous system disorders 10029315 Neuromuscular blockade PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-001954-76 Sponsor Protocol Number: TV48531-CV-40190 Start Date*: 2022-02-23
    Sponsor Name:Ratiopharm GmbH Teva EU Medical Affairs
    Full Title: A Randomized Open Label, Parallel Group Study to Evaluate the Hemodynamic Effects of Cafedrine/Theodrenaline vs Norepinephrine in the Treatment of Intraoperative Arterial Hypotension in Adults afte...
    Medical condition: The purpose of the study is to comparatively evaluate the hemodynamic effects of two treatments when intraoperative hypotension occurs. Patients who require advanced hemodynamic monitoring and dev...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022117 - Injury, poisoning and procedural complications 10062300 Procedural hypotension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-000298-23 Sponsor Protocol Number: PALO-04-07 Start Date*: 2005-07-19
    Sponsor Name:Helsinn Healthcare SA
    Full Title: A Randomized, Double-blind, Multicenter, Parallel Group, Balanced, Stratified Phase 3 Study to Evaluate the Efficacy and the Safety of Single IV Doses of Palonosetron 0.025 mg, 0.050 mg, and 0.075 ...
    Medical condition: Postoperative nausea and vomiting.
    Disease: Version SOC Term Classification Code Term Level
    10054133 PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: CZ (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001496-21 Sponsor Protocol Number: LOC-2013 Start Date*: 2013-06-18
    Sponsor Name:Harry Scheinin
    Full Title: The Neural Mechanisms of Anesthesia and Human Consciousness
    Medical condition: No medical condition or disease involved. The study subjects are healthy volunteers.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012815-16 Sponsor Protocol Number: ROSANNA Start Date*: 2010-03-18
    Sponsor Name:Technische Universität München
    Full Title: Dosis-Wirkungsstudie von Rocuronium unter Propofol-Anästhesie (Rocuronium Dose Finding Study after single shot or steady state propofol anesthesia)
    Medical condition: Rocuronium dose finding study; evaluation of effective doses (ED 50 and ED 95) of rocuronium after single shot or steady state propofol anesthesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029315 Neuromuscular blockade LLT
    9.1 10029315 Neuromuscular blockade PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004087-24 Sponsor Protocol Number: FEN-PAI-3002 Start Date*: 2008-01-29
    Sponsor Name:JANSSEN-CILAG GmbH
    Full Title: Global assessment of treatment with IONSYS and its handling by patients, doctors and nursing staff in the management of acute moderate to severe post-surgery pain in hospitalised patients.
    Medical condition: Acute, moderate to severe postoperative pain after elective surgery in a hospital setting in patients needing at least 24 hours strong opioids for pain therapy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-002630-22 Sponsor Protocol Number: RC31/17/0041 Start Date*: 2018-01-18
    Sponsor Name:University Hospital of Toulouse
    Full Title: Pain prevention during propofol infusion in pediatric: hypnoanalgesia of the hand versus lidocaine.
    Medical condition: surgery under general anaesthetic
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10054799 Perioperative analgesia PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001439-37 Sponsor Protocol Number: MACSevoPregabalin Start Date*: 2019-09-16
    Sponsor Name:Medical University of Vienna, Department of Anaesthesia, General Critical Care and Pain Management
    Full Title: The effect of pregabalin on the minimal alveolar concentration of sevoflurane
    Medical condition: This study aims to investigate the effect of clinically used doses of Pregabalin on the minimum alveolar concentration of sevoflurane to provide more information to clinicians using this adjunctive...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-004181-18 Sponsor Protocol Number: SM-RS-2012 Start Date*: 2012-11-23
    Sponsor Name:Rigshospitalet; Department of Anaesthesia
    Full Title: The effect of dexamethasone in combination with paracetamol and ibuprofen as adjuvant, postoperative pain after herniated disk surgery
    Medical condition: Patients set to lumbar prolapse surgery in general anesthesia
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001668-21 Sponsor Protocol Number: FDE_2014_25 Start Date*: Information not available in EudraCT
    Sponsor Name:Fondation Ophtalomologique A. de Rothschild
    Full Title: Addition of neuromuscular-blocking agents during induction in infants: potential interest in reducing hypoxia episodes
    Medical condition: Chirurgie programmée sous anesthésie générale avec intubation orotrachéale, avec induction inhalatoire prévue
    Disease: Version SOC Term Classification Code Term Level
    21.0 10042613 - Surgical and medical procedures 10002326 Anesthetic induction LLT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-002451-19 Sponsor Protocol Number: 2022-15754 Start Date*: 2022-09-22
    Sponsor Name:Radboudumc
    Full Title: Deep versus moderate neuromuscular blockade during total HIP replacement surgery to improve POstoperative quality of recovery and immune function: a randomized controlled study
    Medical condition: Hip osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000370-31 Sponsor Protocol Number: NKT102260 Start Date*: 2005-05-20
    Sponsor Name:GlaxoSmithKline Group of Companies
    Full Title: A Multicentre, Randomised, Double-blind, Placebo-controlled, Dose-ranging, Parallel Group Phase II Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of the Oral Neurokinin-1 Receptor Ant...
    Medical condition: Post Operative Nausea and Vomiting (PONV) Post Discharge Nausea and Vomiting (PDNV)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: HU (Completed) BE (Completed) DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-003571-39 Sponsor Protocol Number: HC-G-H-0705 Start Date*: 2008-04-23
    Sponsor Name:B. Braun Melsungen AG
    Full Title: Prospective, monocentric, controlled, randomized, double-blind study to compare two different propofol emulsions regarding tolerability and injection pain during the induction of anesthesia in adults
    Medical condition: reduction of injection pain during induction of anaesthesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-005474-77 Sponsor Protocol Number: AGO/2005/004 Start Date*: 2005-12-13
    Sponsor Name:University Hospital Ghent
    Full Title: Validation of a pharmacologic profile of propofol
    Medical condition: Anesthesia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002130-23 Sponsor Protocol Number: TQLnephrectomi_v_1 Start Date*: 2017-07-28
    Sponsor Name:Zealand university hospital Roskilde
    Full Title: Ultrasoundguided Transmuscular Quadratus Lumborum(TQL) block for hand assisted laparoscopic nephrectomy - a randomized controlled trial
    Medical condition: The postoperative pain after Hand assisted lap.nephrectomy operation.Our one year retrospective study of patients with Kidney cancer treated with Hand assisted lap.nephrectomy revealed that, 71% of...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-000704-26 Sponsor Protocol Number: ONSD5 Start Date*: 2018-08-10
    Sponsor Name:
    Full Title: Influence of Endotracheal Intubation versus Endotracheal Intubation with Lidocaine on Intracranial Pressure assessed by Optic Nerve Sheath Diameter
    Medical condition: Patients undergoing surgery at the Erasmus Medical Centre Rotterdam in a period from January 2018 till the end of inclusion.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000956-16 Sponsor Protocol Number: 43907 Start Date*: 2013-07-15
    Sponsor Name:Erasmus Medical Center
    Full Title: Effect of low-dose ketamine on postoperative delirium in patients undergoing noncardiac surgery: a pilot study.
    Medical condition: To investigate the clinical use of Ketamine for the prevention of postoperative delirium in patients undergoing noncardiac surgery.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016641-26 Sponsor Protocol Number: 2009-01-QST Start Date*: 2010-09-27
    Sponsor Name:ZARI - Univeristätsmedizin Göttingen
    Full Title: The influence of propofol and inhalational anesthetics on postoperative pain perception
    Medical condition: ISensory and pain perception in the skin of patients who receive anesthesia with two different anesthetics for elective surgery will be analyzed.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-004167-29 Sponsor Protocol Number: NA Start Date*: 2021-03-15
    Sponsor Name:CHU de Liège
    Full Title: Study of the noninferiority of an oral versus intravenous administration of tranexamic acid in total hip arthroplasty
    Medical condition: Bleeding in total hip arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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