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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,341 result(s) found. Displaying page 739 of 2,218.
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    EudraCT Number: 2008-003993-16 Sponsor Protocol Number: IM-T-hPAM4-02 Start Date*: 2009-04-03
    Sponsor Name:Immunomedics, Inc.
    Full Title: A Phase Ib/II Study of Fractionated 90-Y-hPAM4 Plus Gemcitabine in Patients with Previously Untreated Advanced Pancreatic Cancer
    Medical condition: This is a phase Ib, open-label, dose exploration study of 90-Y-hPAM4 administered as one or more treatment cycles of fractionated radioimmunotherapy in combination with radiosensitizing gemcitabine...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033605 Pancreatic cancer metastatic LLT
    9.1 10033606 Pancreatic cancer non-resectable LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000878-42 Sponsor Protocol Number: DANC-05 Start Date*: 2005-06-20
    Sponsor Name:Consorci Sanitari Terrassa
    Full Title: Ensayo clínico de la eficacia de dos estrategias terapéuticas en el tratamiento de la diverticulitis aguda no complicada
    Medical condition: Diverticulitis aguda no complicada
    Disease:
    Population Age: Adults, Elderly Gender:
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004923-48 Sponsor Protocol Number: 58408356 Start Date*: 2008-09-16
    Sponsor Name:Vejle Sygehus
    Full Title: En fase II undersøgelse af Irinotecan og Panitumumab som 3. linje behandling til patienter med metastaserende colorectal cancer uden KRAS mutationer.
    Medical condition: Metastaserende colorectal cancer uden KRAS mutation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052362 Metastatic colorectal cancer LLT
    9.1 10052360 Colorectal adenocarcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-004152-71 Sponsor Protocol Number: ICA 17043-17 Start Date*: 2008-09-05
    Sponsor Name:Icagen, Inc.
    Full Title: A Phase 2, Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study to Assess the Safety and Efficacy of TWO Weeks of Oral Senicapoc Administration on Allergen challenge in ...
    Medical condition: Asthma.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-000790-38 Sponsor Protocol Number: CRSV 604A 2203 Start Date*: 2008-07-01
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A randomized, double-blind, placebo-controlled study to assess the safety, tolerability, and efficacy of oral RSV604 in healthy adults experimentally infected with respiratory syncytial virus
    Medical condition: infection with respiratory syncytial virus
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-003139-19 Sponsor Protocol Number: CLCI699A2201 Start Date*: 2008-09-12
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multi-center, randomized, double-blind, placebo and active controlled, parallel group, dose finding study to evaluate the efficacy and safety of LCI699 compared to placebo after 8 weeks treatment...
    Medical condition: Essential Hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) SE (Completed) NL (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-006696-36 Sponsor Protocol Number: E2090-E044-318 Start Date*: 2008-09-05
    Sponsor Name:Eisai Limited
    Full Title: Open label Extension Study Following Double-blind, Randomized, Placebo-controlled, Multicentre Study to Assess Efficacy and Safety of Adjunctive Zonisamide in Myoclonic Seizures associated with Idi...
    Medical condition: myoclonic seizures in idiopathic generalised epilepsy (IGE).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054859 Myoclonic epilepsy LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-001605-42 Sponsor Protocol Number: 20060317 Start Date*: 2008-07-14
    Sponsor Name:Amgen Inc
    Full Title: A Multicenter, Double-Blind, 3-Arm, Phase 1b/2 Study in Subjects with Unresectable Locally Advanced or Metastatic Gastric or Esophagogastric Junction Adenocarcinoma to Evaluate the Safety and Effi...
    Medical condition: Unrespectable locally advanced or metastatic gastric or esophagogastric unction adenocarcinoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10017759 Gastric cancer in situ LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) IT (Prematurely Ended) GR (Completed) BE (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2008-005171-95 Sponsor Protocol Number: MESOT-TREM-2008 Start Date*: 2008-09-15
    Sponsor Name:AZIENDA OSPEDALIERA SENESE
    Full Title: A SECOND-LINE, SINGLE ARM, PHASE II CLINICAL STUDY WITH TREMELIMUMAB, A FULLY HUMANIZED ANTI-CTLA-4 MONOCLONAL ANTIBODY, AS MONOTHERAPY IN PATIENTS WITH UNRESECTABLE MALIGNANT MESOTHELIOMA
    Medical condition: PATIENTS WITH UNRESECTABLE MALIGNANT MESOTHELIOMA
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059518 Pleural mesothelioma malignant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-003059-56 Sponsor Protocol Number: ICAND Start Date*: 2008-07-29
    Sponsor Name:ISTITUTO NEUROLOGICO "CARLO BESTA"
    Full Title: Phase II trial to assess safety and efficacy of Iron chelating agent Deferiprone in patients with Pantothenate Kinase-Associated Neurodegeneration – ICAND – Trial
    Medical condition: PKAN
    Disease: Version SOC Term Classification Code Term Level
    9.1 10042259 Structural brain disorders NEC HLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002841-21 Sponsor Protocol Number: H6D-MC-LVHJ(a) Start Date*: 2008-10-28
    Sponsor Name:Eli Lilly and Company
    Full Title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Design, Multinational Study to Evaluate the Efficacy and Safety of Daily Tadalafil for 12 Weeks in Men With Signs and Symptoms of B...
    Medical condition: Benign Prostatic Hyperplasia (BPH)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10004446 Benign prostatic hyperplasia LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-000306-36 Sponsor Protocol Number: 2008-000306-36 Start Date*: 2009-04-16
    Sponsor Name:Region Skåne
    Full Title: Nexavar in Relapsed Peripheral T-cell Non-Hodgkins Lymphoma
    Medical condition: Patients >18 years with relapsed or resitant peripheral T-cell lymphoma, defined as having progressed on 1st or 2nd line therapy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10042973 T-cell lymphoma NOS recurrent LLT
    9.1 10042974 T-cell lymphoma NOS refractory LLT
    9.1 10042979 T-cell lymphoma recurrent LLT
    9.1 10042980 T-cell lymphoma refractory LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-004223-27 Sponsor Protocol Number: GEMCAD-0802 Start Date*: 2008-10-29
    Sponsor Name:GEMCAD
    Full Title: Estudio fase II, de la combinación de Oxaliplatino y Sorafenib en pacientes con Adenocarcinoma gástrico o de la unión gastroesofágica localmente avanzado o metastásico, en progresión tras un esque...
    Medical condition: CANCER GASTRICO
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017758 Gastric cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002315-92 Sponsor Protocol Number: 12013A Start Date*: 2008-11-12
    Sponsor Name:H. Lundbeck A/S
    Full Title: A 52-week, randomised, double-blind, placebo-controlled, parallel-group, safety, tolerability and efficacy study of nalmefene, as needed use, in patients with alcohol dependence
    Medical condition: Alcohol dependence
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001594 Alcohol dependence syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) SK (Completed) EE (Completed) GB (Completed) LV (Completed) HU (Completed) LT (Completed)
    Trial results: View results
    EudraCT Number: 2008-004626-17 Sponsor Protocol Number: 1101/08 Start Date*: 2009-03-23
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Anti-inflammatory and Anti-platelet effect of Clopidogrel and Aspirin vs Aspirin alone in Symptomatic Polyvascular disease and in patients with multiple recurrent cardiovascular events.
    Medical condition: Polyvascular disease and in patients with multiple recurrent cardiovascular events.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10032377 Other peripheral vascular disease LLT
    9.1 10028600 Myocardial ischaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005660-13 Sponsor Protocol Number: He-08-01 Start Date*: 2008-12-11
    Sponsor Name:BOC Ltd.
    Full Title: COPD exacerbation - Heliox Therapy - Assessment Heliox vs. Medical Air in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Pilot Randomised Controlled Trial
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010953 COPD exacerbation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002447-16 Sponsor Protocol Number: 111482 Start Date*: 2008-11-10
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A double-blind, randomized, placebo-controlled Phase III study to assess the efficacy of recMAGE-A3 + AS15 ASCI as adjuvant therapy in patients with MAGE-A3 positive resected stage III melanoma
    Medical condition: Patients with histologically proven stage IIIB or IIIC cutaneous melanoma with macroscopic lymph node involvement suitable for surgical resection. Macroscopic lymph node involvement is defined as c...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10025670 Malignant melanoma stage III PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Prematurely Ended) DE (Prematurely Ended) BE (Completed) CZ (Prematurely Ended) FR (Completed) NL (Prematurely Ended) IT (Prematurely Ended) SE (Prematurely Ended) EE (Prematurely Ended) ES (Completed) AT (Prematurely Ended) GR (Prematurely Ended) BG (Prematurely Ended) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-006435-13 Sponsor Protocol Number: 5065 Start Date*: 2008-10-15
    Sponsor Name:University of Southampton
    Full Title: GRACE (Genomics to combat Resistance against Antibiotics in Community-acquired LRTI in Europe).Workpackage 10: Antibiotic Trial One
    Medical condition: Lower Respiratory Tract Infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008477 Chest infection LLT
    9.1 10024968 Lower respiratory tract infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: View results
    EudraCT Number: 2009-012035-15 Sponsor Protocol Number: CL2-38093-009 Start Date*: 2009-10-07
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Safety and efficacy of S 38093 and donepezil, during 4 weeks, in patients with mild to moderate Alzheimer's Disease. An international, multi-centre, randomised, double-blind, placebo controlled, ph...
    Medical condition: Alzheimer's Disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001896 Alzheimer's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed) IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-002160-34 Sponsor Protocol Number: ELP1020 Start Date*: 2008-10-24
    Sponsor Name:EleosInc Limited
    Full Title: Aezea™ (cenersen) in combination with chemotherapy for the treatment of refractory acute myelogenous leukemia subjects ≥ 55 years of age with inadequate response to a single frontline induction cou...
    Medical condition: Refractory acute myeloid leukemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000884 Acute myeloid leukaemia NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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