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Clinical trials for coronavirus OR corona OR covid OR sars OR acute respiratory OR ards OR pneumonia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44399   clinical trials with a EudraCT protocol, of which   7411   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,841 result(s) found for: coronavirus OR corona OR covid OR sars OR acute respiratory OR ards OR pneumonia. Displaying page 8 of 93.
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    EudraCT Number: 2009-016506-17 Sponsor Protocol Number: OXYGEN-TIPO Start Date*: 2010-04-20
    Sponsor Name:U.O. Terapia intensiva
    Full Title: RIGOROUS NORMOXYA MAINTENANCE IN INTENSIVE CARE UNIT: RANDOMIZED CONTROLLED TRIAL.
    Medical condition: Critically ill patients because of chronic or acute respiratory, circulatory, neurologic, infective, metabolic, renal or hepatic pathologies.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038738 SOC
    9.1 10047065 SOC
    9.1 10019805 SOC
    9.1 10021881 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001721-31 Sponsor Protocol Number: SPON-AK-0420 Start Date*: 2020-05-01
    Sponsor Name:Hampshire Hospitals NHS TRust
    Full Title: Can a sinus rinse and mouth wash reduce viral load in COVID-19 positive individuals?
    Medical condition: Covid-19
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10061986 SARS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2020-001156-18 Sponsor Protocol Number: PanCOVID19 Start Date*: 2020-03-27
    Sponsor Name:Fundación para la investigación Biomedica Hospital Universitario La Paz
    Full Title: Randomized clinical trial to evaluate the efficacy of different treatments in patients with COVID-19 who require hospitalization
    Medical condition: Patients infected with COVID19
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2020-002567-57 Sponsor Protocol Number: 1.0 Start Date*: 2020-11-23
    Sponsor Name:University of Oxford / Clinical Trials and Research Governance
    Full Title: To determine whether administration of almitrine bismesylate can ameliorate hypoxaemia in Covid-19 and augment effectiveness of supplementary oxygen therapy and respiratory support
    Medical condition: Covid-19
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10001053 Acute respiratory failure PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2009-017825-21 Sponsor Protocol Number: EC09/081 Start Date*: 2012-11-19
    Sponsor Name:INSTITUTO ARAGONÉS DE CIENCIAS DE LA SALUD
    Full Title: Prospective, randomised, double-blind study to evaluate the efficacy of treatment with melatonin in adult patients with severe sepsis or septic shock.
    Medical condition: Severe sepsis or septic shock.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021881 - Infections and infestations 10040070 Septic shock PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-006427-18 Sponsor Protocol Number: 2021.143 Start Date*: 2022-08-26
    Sponsor Name:Anna Coquard Rafales
    Full Title: M-POC-O2: high flow nasal cannula oxygen versus conventional oxygen therapy in exacerbated chronic obstructive pulmonary disease (COPD) patients without respiratory acidosis. Pilot Study.
    Medical condition: Patients older than 35 years old with COPD diagnosis (chronic obstructive pulmonary disease) by spirometry, presenting acute exacerbation without respiratory acidosis.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000497-38 Sponsor Protocol Number: DEX-PCH-VMNI Start Date*: 2016-08-23
    Sponsor Name:Ana Vallejo De la Cueva
    Full Title: Dexmedetomidine versus current clinical practice for non-invasive mechanical ventilation: a randomized clinical trial
    Medical condition: Accute respiratory insuffienciency
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016936-11 Sponsor Protocol Number: FAR01-2009 Start Date*: 2011-05-12
    Sponsor Name:Servicio de Farmacia. Hospital Universitario de Bellvitge.
    Full Title: Estudio farmacocinético-farmacodinámico poblacional tras la administración oral o intravenosa de voriconazol en paciente crítico (fase IV)
    Medical condition: paciente crítico en tratamiento con voriconazol oral o endovenoso
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10017537 Fungal lower respiratory tract infections HLT
    13.1 10042613 - Surgical and medical procedures 10066156 Empiric treatment LLT
    13.1 10021881 - Infections and infestations 10061354 Pneumonia fungal PT
    13.1 10022891 - Investigations 10053852 Fungus culture positive LLT
    13.1 10021881 - Infections and infestations 10017533 Fungal infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001823-15 Sponsor Protocol Number: 20CH089 Start Date*: 2020-04-28
    Sponsor Name:CHU de Saint Etienne
    Full Title: Evaluation of the concentration-effect relationship of enoxaparin for thromboembolic prevention in COVID-19 resuscitation patients. COV-ENOX study
    Medical condition: covid-19
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004848 10070267 SARS virus test positive LLT
    21.1 10042613 - Surgical and medical procedures 10022519 Intensive care PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001903-17 Sponsor Protocol Number: HMos-012020 Start Date*: 2020-06-10
    Sponsor Name:HOSPITAL UNIVERISTARIO DE MOSTOLES
    Full Title: A randomized clinical trial (IIIb) of eficacy of a single dose of Tocilizumab or a combination of Tocilizumab plus Vitamin D (single i.m. dose) for the treatment of the COVID-19 hyperimmune complic...
    Medical condition: COVID INFECTION IS A MILD FLU LIKE CONDITION WITH MILD FEVER, DRY COUGH, WIDESPREAD TENDERNESS AND OLFACTORY DISFUNCTION FOLLOWED BY A SERIOUS SITUATION IN SOME 20% OF PATIENTS WITH OVERT FEVER, MA...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001527-14 Sponsor Protocol Number: 1 Start Date*: 2020-04-21
    Sponsor Name:Erasmus MC
    Full Title: COVID-19: addition of azithromycin to chloroquine treatment
    Medical condition: COVID-19
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-002329-56 Sponsor Protocol Number: FISIO Start Date*: 2021-10-19
    Sponsor Name:Sociedad Española de Medicina Intensiva, Crítica y Unidades Coronarias (SEMICYUC)
    Full Title: Exploratory study to evaluate the efficacy and safety of nutritionally administering 1.5 g protein/kg/day vs. 1.0 g protein/kg/day in the catabolic phase of the critically ill patient on mechanical...
    Medical condition: Acquired Weakness in the Intensive Care Unit (DAUCI) of the critically ill patient.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10077255 Intensive care unit acquired weakness PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005797-31 Sponsor Protocol Number: 701004.01.007 Start Date*: 2008-08-14
    Sponsor Name:Dr. Willmar Schwabe GmbH & Co. KG
    Full Title: Efficacy and tolerability of EPs® 7630 film-coated tablets in patients (>=18 years old) with Acute Rhinopharyngitis (ARP)
    Medical condition: Adult patients suffering from Acute Rhinopharyngitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000938 Acute nasopharyngitis (common cold) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000041-14 Sponsor Protocol Number: 269050-80-06-19 Start Date*: 2020-06-19
    Sponsor Name:Norfolk and Norwich University Hospitals NHS Foundation Trust
    Full Title: The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): a randomised placebo-controlled multi-centre clinical trial
    Medical condition: Idiopathic Pulmonary Fibrosis
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10021240 Idiopathic pulmonary fibrosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2020-002230-32 Sponsor Protocol Number: Start Date*: 2020-06-23
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: Rapid Experimental Medicine for COVID-19
    Medical condition: COVID-19
    Disease:
    Population Age: Under 18, Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2018-001109-99 Sponsor Protocol Number: SPON1595-17 Start Date*: 2018-06-29
    Sponsor Name:Cardiff University
    Full Title: A randomised, placebo controlled trial of azithromycin for the prevention of chronic lung disease of prematurity in preterm infants
    Medical condition: Bronchopulomary dysplasia
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10066204 Chronic lung disease of prematurity LLT
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10006475 Bronchopulmonary dysplasia PT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-016925-32 Sponsor Protocol Number: HSJD-CAFEINA-09 Start Date*: 2010-03-09
    Sponsor Name:Hospital Sant Joan de Déu
    Full Title: "CAFEÍNA COMO TRATAMIENTO DE LAS APNEAS EN PACIENTES CON BRONQUIOLITIS AGUDA"
    Medical condition: TRATAMIENTO DE LAS APNEAS EN PACIENTES CON BRONQUIOLITIS AGUDA
    Disease: Version SOC Term Classification Code Term Level
    9 10002972 Apnea LLT
    9 10000686 Acute bronchiolitis LLT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001511-25 Sponsor Protocol Number: IMIB-COLVID-2020-03 Start Date*: 2020-04-14
    Sponsor Name:FFIS
    Full Title: Randomized open-blind controlled trial to study the benefit of Colchicine in Patients with COVID-19
    Medical condition: COVID19
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-005395-35 Sponsor Protocol Number: GatesMRI-COD-01-T01-01 Start Date*: 2020-12-16
    Sponsor Name:Bill & Melinda Gates Medical Research Institute
    Full Title: A randomized, controlled, Phase 2b study to evaluate safety and efficacy of rivaroxaban (Xarelto®) for high risk people with mild COVID-19
    Medical condition: Mild COVID-19 in people who are at high risk for moderate or severe disease due to age, body mass index (BMI) and comorbidities, many of which are also thrombotic risks.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2008-000248-15 Sponsor Protocol Number: Dartagnan3 Start Date*: 2008-08-01
    Sponsor Name:Association pour la promotion de la réanimation médicale à Tours
    Full Title: Amikacine nébulisée à forte dose. Pharmacocinétique dans la pneumonie associée à la ventilation mécanique D’ARTAGNAN 3
    Medical condition: Ventilator associated pneumonia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065153 Ventilator associated pneumonia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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