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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,334 result(s) found. Displaying page 852 of 2,217.
    EudraCT Number: 2004-002788-25 Sponsor Protocol Number: Mirtazapine Combi Start Date*: 2005-08-18
    Sponsor Name:Department of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg
    Full Title: Hippocampal volume in young adults with moderate to severe depression before and after combined antidepressant therapy
    Medical condition: moderate to severe depression (episodes and recurrent diseases)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-006133-32 Sponsor Protocol Number: P04685 Start Date*: 2006-09-20
    Sponsor Name:Allergie-Centrum-Charité
    Full Title: An exploratory phase IV, randomised, double-blind, placebo controlled crossover study to assess and compare the effects of 5 mg vs. 20 mg Desloratadine on the development of experimentally induced ...
    Medical condition: Acquired cold urticaria (ACU) is a frequent form of physical urticaria that is characterized by the development of wheal and flare type skin reactions after cold exposure.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10046741 Urticaria cold LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-002237-20 Sponsor Protocol Number: ATS K021 Start Date*: 2006-08-21
    Sponsor Name:Takeda Pharma GmbH
    Full Title: Pilot trial studying the Effects of Pioglitazone in Comparison to Placebo on Myocardial Function and Oxidative Stress in Patients with Type II Diabetes and Insulin Resistance undergoing elective PTCA
    Medical condition: Type 2 diabetic patients treated with oral agents except PPAR gamma agonists and / or patients with insulin resistance measured by IRIS score > 50 with stable coronary artery disease and supposed e...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001544-31 Sponsor Protocol Number: PATP1001 Start Date*: 2007-04-12
    Sponsor Name:Moorfields Eye Hospital
    Full Title: A randomised, double-masked, phase 3 study of the efficacy and safety of Avastin® (bevacizumab) intravitreal injections compared to best available therapy in subjects with choroidal neovasculariza...
    Medical condition: Exudative age-related macular degeneration
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002771-40 Sponsor Protocol Number: PIX-01 Start Date*: 2006-08-28
    Sponsor Name:S.G.O. Johansson, MD PhD Professor
    Full Title: Importance of IgE antibody fraction size on allergen sensitivity of basophils from cat allergic patients on Xolair. A pilot study.
    Medical condition: Allergic asthma and or rhinitis due to allergy to cat dander
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001200-36 Sponsor Protocol Number: AVA001 Start Date*: 2006-09-18
    Sponsor Name:St. Eriks Eye Hospital [...]
    1. St. Eriks Eye Hospital
    2.
    3. St. Eriks Eye Hospital
    4.
    Full Title: A prospective, randomized, masked and controlled trial of intravitreal bevacizumab (Avastin) versus verteporfin photodynamic therapy (PDT) in patients with neovascular age-related macular degenera...
    Medical condition: Age-related macular degeneration (AMD) is the leading cause of visual impairment and social blindness in people 60 years or older. Approximately 75% of patients with severe visual loss exhibit ne...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-002919-24 Sponsor Protocol Number: CSMS995BDE16 Start Date*: 2006-02-09
    Sponsor Name:Novartis Pharma GmbH
    Full Title: A multicenter, single arm, proof of concept study to investigate in a first stage the efficacy of a combination therapy of Sandostatin® LAR® and Cabergoline, optionally followed by a combination of...
    Medical condition: acromegaly
    Disease: Version SOC Term Classification Code Term Level
    M15 10000599 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-003834-14 Sponsor Protocol Number: OXC-039/K Start Date*: 2006-09-21
    Sponsor Name:Desitin Arzneimittel GmbH
    Full Title: Safety and Efficacy of Novel Modified Release Formulation of Oxacarbazepine (OXC MR) vs an Immediate Release Oxacarbazepine (OXC IR) Product in Patients with Partial Epilepsy. Open-Labelled, Contro...
    Medical condition: Refractory partial epilepsy, with or without secondary generalisation
    Disease: Version SOC Term Classification Code Term Level
    9.0 10065336 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-005170-80 Sponsor Protocol Number: VB4-845-01-IIIA Start Date*: 2006-11-01
    Sponsor Name:Viventia Biotech Inc.
    Full Title: A RANDOMIZED, MULTICENTRE THERAPEUTIC CONFIRMATORY STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PROXINIUM™ PLUS BEST SUPPORTIVE CARE VERSUS BEST SUPPORTIVE CARE ALONE IN PATIENTS WITH ADVANCED SQUA...
    Medical condition: Advanced Ep-CAM Positive Squamous Cell Carcinoma of the Head and Neck
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) DE (Prematurely Ended) FR (Ongoing) HU (Prematurely Ended) ES (Ongoing) SK (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005638-10 Sponsor Protocol Number: SST-Pr-2-2005 Start Date*: 2007-02-12
    Sponsor Name:University of Münster
    Full Title: Evaluation of the antipruritic effect of Elidel (pimecrolimus) in non-atopic pruritic disease
    Medical condition: Prurigo nodularis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10037084 Prurigo nodularis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-000105-65 Sponsor Protocol Number: 1 Start Date*: 2006-08-30
    Sponsor Name:Medical University of Vienna, Department of Internal Med. I, Division of Infectious Diseases
    Full Title: Comparative study of the efficacy and tolerance of intravenously administered azithromycin (1.5 g) given either as a single dose or over a 3 day period in patients with community-acquired pneumonia
    Medical condition: community aquired pneumonia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-002216-25 Sponsor Protocol Number: PDT409 Start Date*: 2006-06-26
    Sponsor Name:Amersham Health, S.A. (filial de GE Healthcare Ltd)
    Full Title: Ensayo en fase 4 multicéntrico, aleatorizado, abierto y comparativo para evaluar las modificaciones en el manejo clínico después de una tomografía con DaTSCAN en sujetos con parkinsonismo clínicame...
    Medical condition: The subjects included in this trial will have clinically uncertain parkinsonism in a general neurologist setting.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-000287-84 Sponsor Protocol Number: 101 Start Date*: 2006-07-11
    Sponsor Name:Sykehuset Innlandet HF
    Full Title: Seponering av antipsykotika og antidepressiva hos demente pasienter med APSD i sykehjem - en åpen studie.
    Medical condition: The included patients are all elderly people with dementia of Alzheimer or vascular type. Their dementia is moderate or severe and they all have Behavioral or Psychological Symptomes (BPSD).
    Disease: Version SOC Term Classification Code Term Level
    8.1 10057678 Vascular dementia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-005197-23 Sponsor Protocol Number: 1/1 Start Date*: 2005-10-06
    Sponsor Name:Klinik und Poliklinik für Augenheilkunde der Universität Regensburg
    Full Title: Funktionelle Ergebnisse der intravitrealen Injektion von Triamcinolonacetonid im Vergleich zur konventionellen Lasertherapie bei diabetischem Makulaödem.
    Medical condition: Patients with diffuse macular edema due to diabetic retinopathy and decrease in visual acuity.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-002068-27 Sponsor Protocol Number: 500 Start Date*: 2006-04-20
    Sponsor Name:Medical University of Vienna
    Full Title: Prevention of venous thrombosis in cancer patients: A prospective, randomized, double-blind study comparing two different dosages of low-molecular weight heparin
    Medical condition: cancer patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-006118-17 Sponsor Protocol Number: B3I105940 Start Date*: 2006-08-17
    Sponsor Name:GlaxoSmithKline Research and Development Limited
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Crossover, Phase IIa Study to Evaluate Efficacy and Safety of the beta3-Adrenergic Receptor Agonist Solabegron in Subjects with Irritable Bowel Syndrome
    Medical condition: Irritable Bowel Syndrome (IBS)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000526-31 Sponsor Protocol Number: BT2006003 Start Date*: 2007-01-03
    Sponsor Name:Section of Clinical Pain Research, Department of Molecular Medicine and Surgery Karolinska Institute
    Full Title: Brush-evoked allodynia in patients with peripheral neuropathy before and following intravenous infusion of ondansetron. A randomised, double-blind, placebo controlled, cross-over study.
    Medical condition: Peripheral neuropathy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10029331 Neuropathy peripheral LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2004-005041-35 Sponsor Protocol Number: AN 0104 Start Date*: 2005-10-19
    Sponsor Name:University Hospital Basel, Dept. of Angiology
    Full Title: The effects of physical training, Aspirin, and Clopidogrel on the walking capacity of patients with stage II peripheral arterial disease
    Medical condition: Peripheral arterial disease, intermittent claudication
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002407-14 Sponsor Protocol Number: 106915 Start Date*: 2006-10-24
    Sponsor Name:GlaxoSmithKline Research, European Medical Governance
    Full Title: Eptifibatide Versus Abciximab in primary PCI for Acute ST elevation Myocardial Infarction (EVA-AMI)
    Medical condition: Primary percutaneous coronary intervention (PCI) for ST-elevation Myocardial Infarction (STEMI)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10028596 Myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000860-10 Sponsor Protocol Number: 10729 Start Date*: 2006-06-30
    Sponsor Name:H. Lundbeck A/S
    Full Title: An Open-Label Study Investigating the Specific Effects of Memantine in Institutionalised Patients with Alzheimer’s Disease
    Medical condition: Effects of memantine treatment in institutionalised patients with Alzheimer's Disease.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) BE (Completed) GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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