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Clinical trials for Intranasal

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    280 result(s) found for: Intranasal. Displaying page 9 of 14.
    EudraCT Number: 2007-002245-20 Sponsor Protocol Number: EICAS Start Date*: 2008-08-15
    Sponsor Name:Zentralinstitut für Seelische Gesundheit Mannheim
    Full Title: Evaluation of potential central glucoregulatory compounds to treat/ameliorate the symptoms of schizophrenia: a proof-of-concept study in healthy volunteers
    Medical condition: Basic ressearch on schizophrenia. This is a proof-of-concept trial. The hypothesis is that substances that regulate the central glucose utilisation might ameliorate symptoms of schizophrenic psyc...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039626 Schizophrenia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003423-30 Sponsor Protocol Number: 2017-RCT-OX Start Date*: 2017-12-12
    Sponsor Name:Dutch Growth Research Foundation
    Full Title: Randomized, double-blind, placebo-controlled oxytocin and dose-response trial in children with Prader-Willi syndrome. Effects on social behaviour.
    Medical condition: Prader-Willi syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10036476 Prader-Willi syndrome PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006000-11 Sponsor Protocol Number: IPR107498 Start Date*: 2007-01-01
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: An 8 day, randomised, double blinded, placebo-controlled 2-way crossover trial of repeat doses of intranasal GSK256066 and placebo in the Vienna Challenge Chamber in subjects with seasonal allergic...
    Medical condition: Seasonal allergic rhinitis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039776 Seasonal allergic rhinitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-003067-59 Sponsor Protocol Number: AOB/2013/01 Start Date*: 2017-01-25
    Sponsor Name:AZIENDA OSPEDALIERA G. BROTZU
    Full Title: A single-center, randomized, double-blind, placebo-controlled, cross-over study of intranasal oxytocin in young adults with Autism Spectrum Disorder
    Medical condition: Autism Spectrum Disorder
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004873 10003805 Autism LLT
    Population Age: Adults Gender: Male
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-003463-97 Sponsor Protocol Number: RVL-VRL01 Start Date*: 2021-09-24
    Sponsor Name:Revelation Biosciences, Inc.
    Full Title: A Phase IIb Study Assessing Prophylactic Efficacy of Intranasal REVTx-99 in an H3N2 Influenza Challenge Model in Healthy Subjects.
    Medical condition: Influenza A
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10022000 Influenza PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002451-26 Sponsor Protocol Number: 538264464328 Start Date*: 2015-05-15
    Sponsor Name:Department of Psychiatry, Helsinki University Central Hospital
    Full Title: The effect of intranasal ketamine on suicidality in severely depressed and suicidal patients. Randomized, placebo-controlled study
    Medical condition: Depression
    Disease: Version SOC Term Classification Code Term Level
    17.1 10037175 - Psychiatric disorders 10012378 Depression PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-000585-13 Sponsor Protocol Number: MI-CP111 Start Date*: 2004-09-01
    Sponsor Name:MedImmune Vaccines, Inc.
    Full Title: A Randomized, Double-Blind Trial to Assess the Safety and Relative Efficacy of CAIV-T Against Inactivated Influenza Vaccine in Children 6–59 Months of Age
    Medical condition: Influenza
    Disease: Version SOC Term Classification Code Term Level
    3.2 10022000
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed) SE (Completed) CZ (Completed) ES (Completed) IS (Completed) GB (Completed) IT (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001431-58 Sponsor Protocol Number: ROX-2007-01 Start Date*: 2007-09-10
    Sponsor Name:ROXRO PHARMA, Inc.
    Full Title: A Phase 2, Double-Blind, Randomized, Placebo-Controlled Study of the Safety, Tolerability, and Analgesic Efficacy of Ketorolac Tromethamine Administered Intranasally for the Acute Treatment of Mig...
    Medical condition: Migraine
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027599 Migraine LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004745-18 Sponsor Protocol Number: FFR30008 Start Date*: 2005-03-17
    Sponsor Name:GlaxoSmithKline Research & Development
    Full Title: A randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the safety and efficacy of once-daily, intranasal administration of GW685698X Aqueous Nasal Spray 50mcg...
    Medical condition: Perennial Allergic Rhinitis
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed) SK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-004642-32 Sponsor Protocol Number: 2007ENT03 Start Date*: 2008-10-10
    Sponsor Name:University of East Anglia
    Full Title: THE EFFECT OF THEOPHYLLINE IN PATIENTS WITH RHINITIS
    Medical condition: Rhinitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001723 Allergic rhinitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-004919-36 Sponsor Protocol Number: P05529 Start Date*: 2015-02-24
    Sponsor Name:Schering-Plough Research Institute, a Division of Schering Corporation
    Full Title: PLACEBO-CONTROLLED STUDY OF MOMETASONE FUROATE NASAL SPRAY (MFNS) 200 MCG QD IN THE RELIEF OF NASAL CONGESTION ASSOCIATED WITH SEASONAL ALLERGIC RHINITIS (SAR)
    Medical condition: SEASONAL ALLERGIC RHINITIS (SAR)
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2014-004918-28 Sponsor Protocol Number: P05528 Start Date*: 2015-02-24
    Sponsor Name:Schering-Plough Research Institute, a Division of Schering Corporation
    Full Title: PLACEBO-CONTROLLED STUDY OF MOMETASONE FUROATE NASAL SPRAY (MFNS) 200 MCG QD IN THE RELIEF OF NASAL CONGESTION ASSOCIATED WITH SEASONAL ALLERGIC RHINITIS (SAR) (Protocol No. P05528)
    Medical condition: Seasonal Allergic Rhinitis
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2011-004183-29 Sponsor Protocol Number: DERC-03 Start Date*: 2014-06-27
    Sponsor Name:Dermal Laboratories
    Full Title: A randomised, placebo-controlled trial to investigate the effectiveness of an antimicrobial product in the elimination of Staphylococcus aureus colonisation from the anterior nares of adult subject...
    Medical condition: Nasal colonisation with Staphylococcus aureus
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004862 10069719 Bacterial colonisation LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-004920-23 Sponsor Protocol Number: P05583 Start Date*: 2015-02-24
    Sponsor Name:Schering-Plough Research Institute, a Division of Schering Corporation
    Full Title: PLACEBO-CONTROLLED STUDY OF MOMETASONE FUROATE NASAL SPRAY (MFNS) 200 MCG QD IN THE RELIEF OF NASAL CONGESTION ASSOCIATED WITH SEASONAL ALLERGIC RHINITIS (SAR) (Protocol No. P05583)
    Medical condition: SEASONAL ALLERGIC RHINITIS
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2007-003194-82 Sponsor Protocol Number: VAI03 Start Date*: 2007-09-05
    Sponsor Name:University of Dundee
    Full Title: A proof of concept study to evaluate differential tachyphylaxis of α1 and α2 adrenoreceptor mediated decongestant response to oxymetazoline and its acute reversal by corticosteroid in healthy volun...
    Medical condition: This is a proof of concept trial on Healthy Volunteers to evaluate the tolerance of nasal adrenoreceptors to prolonged decongestant use and upregulation by intranasal steroids. The medical conditio...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10043087 Tachyphylaxis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-000453-44 Sponsor Protocol Number: NL42746.058.12 Start Date*: 2013-06-19
    Sponsor Name:
    Full Title: The full scope of oxytocinergic influences on the parental brain: Maternal defensiveness and grandparent-child interactions
    Medical condition: There are no medical conditions or diseases under investigation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10033329 Oxytocin PT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011529-15 Sponsor Protocol Number: GHB-CS04, VIE-CS-002 Start Date*: 2010-05-26
    Sponsor Name:AVIR Green Hills Biotechnology Research Development Trade AG
    Full Title: A Phase II Prospective, Randomised, Double-Blind, Placebo-Controlled Study to Assess the Efficacy of the Influenza Vaccine GHB11L1 Administered Intranasally Against a Controlled Influenza Virus Cha...
    Medical condition: Prophylaxis of Influenza A (H1N1) infection.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022000 Influenza LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-004434-14 Sponsor Protocol Number: FFR103184 Start Date*: 2005-04-05
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A randomized, double-blind, placebo-controlled, parallel group, multicenter two week study to evaluate the efficacy and safety of once-daily, intranasal administration of GW685698X aqueous nasal sp...
    Medical condition: Seasonal allergic rhinitis (SAR)
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) LT (Completed) EE (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2007-001850-18 Sponsor Protocol Number: 2007SA02 Start Date*: 2007-07-04
    Sponsor Name:NHS Tayside
    Full Title: A randomised controlled study on the effects of Mitomycin C versus placebo in adult endoscopic dacrocystorhinostomy
    Medical condition: Watery or sticky eye due to blockage of tear ducts
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023622 Lacrimal duct obstruction LLT
    9.1 10023623 Lacrimal duct obstruction (acquired) LLT
    9.1 10023634 Lacrimal mucocele LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-003291-19 Sponsor Protocol Number: VAI01 Start Date*: 2009-07-30
    Sponsor Name:University of Dundee
    Full Title: A proof of concept study to evaluate if concomitant topical intranasal steroid prevents tolerance and rebound congestion due to regular oxymetazoline in persistent allergic rhinitis
    Medical condition: Allergic Rhinitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001723 Allergic rhinitis LLT
    9.1 10039090 Rhinitis medicamentosa LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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