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Clinical trials for Surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    5,833 result(s) found for: Surgery. Displaying page 9 of 292.
    «« First « Previous 5  6  7  8  9  10  11  12  13  Next» Last»»
    EudraCT Number: 2018-001430-18 Sponsor Protocol Number: 5101127 Start Date*: 2019-08-12
    Sponsor Name:Kuopio University Hospital
    Full Title: Does postoperative intravenous corticosteroid and intravenous beta blocker management prevent atrial fibrillation after cardiac surgery?
    Medical condition: new onset atrial fibrillation and paroxysmal atrial fibrillation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001761-42 Sponsor Protocol Number: 0869-131 Start Date*: 2006-06-12
    Sponsor Name:Merck & Co., Inc
    Full Title: A Randomized, Double-Blind, Active Comparator-Controlled, Parallel-Group Study Conducted Under In-House Blinding Conditions, to Examine the Safety, Tolerability, and Efficacy of Aprepitant for the ...
    Medical condition: Postoperative Nausea and Vomiting
    Disease: Version SOC Term Classification Code Term Level
    8.1 10036238 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Prematurely Ended) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-005287-24 Sponsor Protocol Number: BAR104 Start Date*: 2005-06-28
    Sponsor Name:Univ.-Kl. f.Augenheilkunde und Optometrie Wien
    Full Title: Effect of diclofenac-sodium, unpreserved diclofenac-sodium or ketorolac on the inflammatory response after cataract surgery
    Medical condition: intraocular inflammatory reaction after cataract-surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-002309-39 Sponsor Protocol Number: 60/2011 Start Date*: 2016-07-08
    Sponsor Name:Osakidetza
    Full Title: EFFECTIVENESS OF ROPIVACAINE 0.1% INTRAPERITONEAL IN POSTOPERATIVE PAIN CONTROL IN GYNECOLOGIC LAPAROSCOPIC SURGERY "
    Medical condition: EFECTIVENESS OF ROPIVACAINE 0,1% FOR PAIN CONTROL AFTER LAPAROSCOPIC GYNECOLOGICAL SURGERY
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001852-11 Sponsor Protocol Number: ARG1 Start Date*: 2006-10-13
    Sponsor Name:Medical University of Vienna
    Full Title: Influence of L-Arginine on perfusion in patients receiving peripheral bypass surgery (Einfluss von L-Arginin auf die Perfusion bei Patienten mit peripheren Bypassoperationen)
    Medical condition: In general, ischemia and reperfusion are main causes for tissue damage and consequently for organ damage after surgery. Particularily, patients suffering from a peripheral occlusive disease show a ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2020-000135-47 Sponsor Protocol Number: 21/103 Start Date*: 2021-11-02
    Sponsor Name:Hospital Universitario Fundación Alcorcón
    Full Title: Analgesic efficacy of erector spinae plane block in lumbar spine surgery: a prospective, randomized and double blind study.
    Medical condition: The analgesic efficacy of erector spinae plane block in lumbar spine surgery. Infiltration of local anesthetic in this plane may lower postoperative pain.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001079-35 Sponsor Protocol Number: PRPK Start Date*: 2019-08-29
    Sponsor Name:Cliniques universitaires Saint-Luc
    Full Title: A prospective randomized study in ambulatory patients undergoing upper limb bone surgery under single shot axillary plexus block.
    Medical condition: Do patients who are very painful when the axillary block wears off after bone surgery of the upper limb have a pre-existing central sensitization? Could this “rebound pain” be prevented by pre-inc...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2017-002494-19 Sponsor Protocol Number: NL61864.041.17 Start Date*: 2017-12-21
    Sponsor Name:UMC Utrecht
    Full Title: Dexamethasone for Cardiac Surgery trial: a novel 'Standard Practice Preference-Randomised Consent' Design. A PILOT STUDY
    Medical condition: Inflammatory response to cardiac surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-000638-17 Sponsor Protocol Number: 44107 Start Date*: 2021-03-30
    Sponsor Name:Oslo University Hospital
    Full Title: ZOLEDRONATE EARLY TO HIP FRACTURE PATIENTS – SAFE AND EFFECTIVE? A DOUBLE-BLINDED RANDOMIZED CONTROLLED TREATMENT STRATEGY TRIAL ON ZOLEDRONATE IN HIP FRACTURE PATIENTS THE ZEBRA TRIAL
    Medical condition: Osteoporosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-001714-29 Sponsor Protocol Number: 290975 Start Date*: 2017-08-09
    Sponsor Name:Helsinki University hospital
    Full Title: Influence of epidural analgesia on opioid consumption and patients recovery after laparoskopic colorectal surgery.
    Medical condition: Compare epidural and conventional pain treatment after laparoskopic colorectal surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004514-10 Sponsor Protocol Number: 00173 Start Date*: 2017-03-08
    Sponsor Name:Raimo Tuuminen
    Full Title: Pre and post-operative corticosteroid and NSAID combination treatment in cataract surgery of diabetic patient
    Medical condition: Cataract senilis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004784-40 Sponsor Protocol Number: 00176 Start Date*: 2017-03-03
    Sponsor Name:Raimo Tuuminen
    Full Title: Anti-inflammatory medication in cataract surgery of pseudoexfoliation eyes
    Medical condition: Cataract senilis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000992-12 Sponsor Protocol Number: HIPP-CABG Start Date*: 2008-03-27
    Sponsor Name:Academic Medical Center
    Full Title: Organ protection by noble gases – A clinical study to investigate Helium induced Pre- and Postconditioning in patients undergoing coronary artery bypass surgery (HIPP-CABG).
    Medical condition: patients undergoing coronary artery bypass surgery, helium induced pre- and postconditioning
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004083-62 Sponsor Protocol Number: steroid3848 Start Date*: 2019-09-06
    Sponsor Name:Semmelweis University, Oro-Maxillofacial Surgery and Stomatology
    Full Title: Effect of preoperative intramasseteric methylprednisolone injection on the post-operative sequelae of lower third molar surgery: a placebo controlled, randomized, double-blinded study
    Medical condition: post-operative swelling, trismus, pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-004713-91 Sponsor Protocol Number: ROPISPINE Start Date*: 2015-02-09
    Sponsor Name:Universitair Ziekenhuis Brussel
    Full Title: Epidural ropivacaine as part of a multimodal postoperative pain treatment following thoracolumbar spinal fusion surgery.
    Medical condition: Spine Surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2017-004038-28 Sponsor Protocol Number: Zalviso Start Date*: 2018-02-21
    Sponsor Name:Universitair Ziekenhuis Brussel
    Full Title: Comparative Prospective Randomized Study in Postoperative Cardiac Surgery Patients on Analgesia with Morphine Continuous Infusion or Sublingual Sufentanil (Zalviso®).
    Medical condition: -Postoperative pain treatment after cardiac surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-004465-32 Sponsor Protocol Number: 2011/386 Start Date*: 2011-12-12
    Sponsor Name:Dept. of Cardiothoracic & Vascular Surgery, Aarhus University Hospital, Skejby
    Full Title: Can post-operative treatment with parathyroid hormone enhance bone healing and quality of newly formed bone after sternotomy in cardiac surgery patients?
    Medical condition: Sternotomy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10051332 Surgical procedure LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-004990-24 Sponsor Protocol Number: ZKS000529 Start Date*: 2008-05-05
    Sponsor Name:University Medical Center Freiburg
    Full Title: Comparison of the concentrations of the antibiotic compound Daptomycin in serum, cartilage-, muscle and subcutaneous tissue after a preoperative intravenous administration (Klinische Studie zum ...
    Medical condition: Elective orthopedic surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10042609 Surgery PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002096-29 Sponsor Protocol Number: iVRCT Start Date*: 2015-07-20
    Sponsor Name:Speising Orthopaedic Hospital Vienna
    Full Title: Application of Intrawound Vancomycin Powder in Spinal Fusion Surgery to Reduce Postoperative Surgical Site Infections - A Prospective Randomized Controlled Trial
    Medical condition: Postoperative surgical site infections (deep and superficial) after spinal fusion surgery
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004862 10074392 Deep postoperative wound infection LLT
    18.0 100000004862 10074393 Superficial postoperative wound infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-005124-14 Sponsor Protocol Number: 2005DICPAED Start Date*: 2007-07-12
    Sponsor Name:Joint Sponsor: University of Glasgow with NHS greater Glasgow and Clyde [...]
    1. Joint Sponsor: University of Glasgow with NHS greater Glasgow and Clyde
    2. Joint Sponsor: University of Glasgow with NHS Greater Glasgow and Clyde
    Full Title: The unlicensed and off-label use of diclofenac in paediatric patients: Pharmacokinetic, pharmacodynamic and pharmacogenomic evlauations
    Medical condition: Children undergoing surgery for orthapaedic, ENT, renal or abdominal conditions
    Disease: Version SOC Term Classification Code Term Level
    9.1 10042609 Surgery LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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