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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 961 of 2,219.
    EudraCT Number: 2005-000412-27 Sponsor Protocol Number: ARG-CS3-001 Start Date*: 2005-08-22
    Sponsor Name:Arginox Pharmaceuticals, Inc.
    Full Title: A Phase III International Multi-center, Prospective, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of Nitric Oxide Synthase Inhibition with Tilarginine Acetat...
    Medical condition: It is the intent of the proposed study to further evaluate the safety and efficacy of Tilarginine Acetate Injection as a novel, mortality reducing therapeutic drug for patients with cardiogenic sho...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Prematurely Ended) HU (Prematurely Ended) AT (Completed) CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-004377-28 Sponsor Protocol Number: CFTY720A0124E1 Start Date*: 2005-02-03
    Sponsor Name:Novartis Pharma AG
    Full Title: A two-year extension to a one-year, multicenter, partially blinded, double-dummy, randomized study to evaluate the efficacy and safety of FTY720 combined with reduced-dose or full-dose Neoral and c...
    Medical condition: Prophylaxis of kidney allograft rejection in de novo adult renal transplant recipients
    Disease: Version SOC Term Classification Code Term Level
    7.0 10023439 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004993-95 Sponsor Protocol Number: CL-033-III-02 Start Date*: 2005-08-18
    Sponsor Name:IDEA AG
    Full Title: A double blind, placebo-controlled evaluation of dose realted safety and efficacy of epicutaneously applied IDEA-033 for 3 months treatment of osteoarthritis of the knee
    Medical condition: Osteoarthritis of the knee joint
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002163-84 Sponsor Protocol Number: BY9010/M1-145 Start Date*: 2005-07-18
    Sponsor Name:ALTANA Pharma AG
    Full Title: Comparison of the Efficacy and Safety of 160 µg Ciclesonide Administered Once Daily in the Evening with or without Different Spacer Types in Patients with Asthma A randomized, open-label, three-ar...
    Medical condition: asthma bronchial
    Disease: Version SOC Term Classification Code Term Level
    8.0 10003555 llt
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) IT (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-000777-21 Sponsor Protocol Number: OncoVEXGM-CSF/004/04 Start Date*: 2005-07-06
    Sponsor Name:BioVex Ltd
    Full Title: AN EXPLORATORY STUDY OF THE SAFETY AND BIOLOGICAL ACTIVITY OF ONCOVEXGM-CSF IN COMBINATION WITH RADIOTHERAPY AND CISPLATIN IN THE TREATMENT OF LOCALLY ADVANCED EPITHELIAL CANCER OF THE HEAD AND NECK
    Medical condition: Locally advanced epithelial cancer of the head and neck.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10041823 Squamous cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001278-28 Sponsor Protocol Number: IGT-FRA-0030-I Start Date*: 2005-07-27
    Sponsor Name:Technical University of Munich
    Full Title: Untersuchungen über die Wirkung der gestörten Glucosetoleranz auf die renale und systemische Hämodynamik und das renin-Angiotensin-System sowie deren pharmakologische Beeinflussung mittels AT1-Reze...
    Medical condition: Es werden Patienten untersucht, die eine gestörte Glucosetoleranz (impaired glucose tolerance, IGT aufweisen. Diese wird auch als "Prädiabetes" bezeichnet. Diese Erkrankung liegt dann vor, wenn der...
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000973-41 Sponsor Protocol Number: Etx and portal embolisation Start Date*: 2008-04-09
    Sponsor Name:Karolinska University Hospital, Huddinge
    Full Title: Efficacy of cetuximab for preventing progression of CRC liver metastases after selective portal embolisation
    Medical condition: Patients with colorectal cancer and livermetastases planned for hemihepatectomy following portal embolisation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002567-24 Sponsor Protocol Number: M120204-063 Start Date*: 2005-04-04
    Sponsor Name:Millennium Pharmaceuticals, Inc.
    Full Title: A Phase 2a Magnetic Resonance Imaging Study of the Safety and Efficacy of MLN1202 in patients with Multiple Sclerosis
    Medical condition: The purpose of this study is to investigate the safety, PK parameters, PD responses, and clinical responses of multiple dose administration of MLN1202 in patients with relapsing remitting multiple ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) GB (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2004-002058-69 Sponsor Protocol Number: UHL 9609 Start Date*: 2004-11-17
    Sponsor Name:University Hospitals of Leicester NHS Trust
    Full Title: The use of nicotine patches for the treatment of psoriasis
    Medical condition: Psoriasis - moderate to severe
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-002116-28 Sponsor Protocol Number: 2004CV12 Start Date*: 2005-03-29
    Sponsor Name:University of Dundee
    Full Title: Does Vitamin D supplementation improve function and quality of life in older heart failure patients - A double blind, placebo controlled trial
    Medical condition: Chronic Heart Failure
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-000145-35 Sponsor Protocol Number: 0431-803 Start Date*: 2008-04-25
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Phase III, Multicenter, Double-Blind, Randmoized Study to Evaluate the Safety and Efficacy of the Addition of Sitagliptin Compared With the Addition of Glimepiride in Patients With Type 2 Diabete...
    Medical condition: type II diabetes mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) FR (Completed) DK (Completed) AT (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-000372-41 Sponsor Protocol Number: D5890L00012 Start Date*: 2005-06-19
    Sponsor Name:AstraZeneca UK Limited
    Full Title: Real life effectiveness in asthma of Symbicort® Single Inhaler Therapy (RELEASE)
    Medical condition: This is a Phase IIIb Trial to be conducted in adult, uncontrolled asthmatic patients.
    Disease: Version SOC Term Classification Code Term Level
    10003553
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001530-32 Sponsor Protocol Number: 200504012 Start Date*: 2006-09-28
    Sponsor Name:Jan Engvall
    Full Title: Can pharmacological stress test at MRI of the heart improve the detection of coronary stenoses/Kan belastningsprov i magnetkamera ge förbättrad diagnostik av kranskärlsförträngningar?
    Medical condition: Patients in the first week post myocardial infarction are referred for early coronary angiography. Often, balloon dilatation is performed at the time of angiography. It is debatable which stenose...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000685-39 Sponsor Protocol Number: 2005-1 Start Date*: 2005-05-18
    Sponsor Name:Universitetssjukhuset Örebro
    Full Title: Postoperativ smärtlindring och mobilisering efter per- och postoperativ injektion av ropivakin, ketorolak och adrenalin givet i operationsområdet, infiltrativt och i knäleden, vid enkammarknäplasti...
    Medical condition: Post-operativ smärta efter enkammarknäplastikoperation, s k miniknä
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-005244-28 Sponsor Protocol Number: GPOH-HD 2002 Pilot / VECOPA Start Date*: 2005-05-19
    Sponsor Name:Universität Leipzig
    Full Title: Pilotstudie zur Therapieoptimierungsstudie für den Morbus Hodgkin bei Kindern und Jugendlichen Prüfung der Verträglichkeit der Chemotherapiekombination VECOPA bei Patienten der Therapiegruppen 2 ...
    Medical condition: Pilotstudie zur Therapieoptimierungsstudie für den Morbus Hodgkin bei Kindern und Jugendlichen Prüfung der Verträglichkeit der Chemotherapiekombination VECOPA bei Patienten der Therapiegruppen 2 ...
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000063-10 Sponsor Protocol Number: RD.03.SPR.29040 Start Date*: 2004-10-07
    Sponsor Name:Galderma R&D
    Full Title: A comparison of Metvix PDT with simple excision surgery in subjects with superficial Basal cell Carcinoma (sBCC)
    Medical condition: Superficial Basal Cell Carcinomas, occurring mostly on trunk and extremities (‎4,‎5), are progressively spreading, slow growing cancers. They can be difficult to diagnose and often mistaken for oth...
    Disease: Version SOC Term Classification Code Term Level
    10042503 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-003699-13 Sponsor Protocol Number: MAK-BLA-202 Start Date*: 2005-03-08
    Sponsor Name:INMUNO DESIGNED MOLECULES (IDM)
    Full Title: Phase II/III, Multicenter, Open-label, Randomized Study Comparing Autologous Intravesical Macrophage Cell Therapy (“Bexidem”) to Intravesical BCG-Therapy in Patients With Superficial Papillary Blad...
    Medical condition: BLADDER CANCER AFTER TRANSURETRHAL RESECTION
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002216-28 Sponsor Protocol Number: A3711028 Start Date*: 2005-01-13
    Sponsor Name:Pfizer Limited
    Full Title: A multi-center, multinational, randomized, double-blind, placebo-controlled, proof of concept trial to assess the effects of a subject-optimized dose of UK-369,003 Modified Release on exercise capa...
    Medical condition: Pulmonary hypertension associated with chronic obstructive pulmonary disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-002327-13 Sponsor Protocol Number: 2004VS002 Start Date*: 2005-07-01
    Sponsor Name:Heart of England NHS Foundation Trust
    Full Title: Mild to moderate intermittent claudication: the clinical and cost-effectiveness of supervised exercise programmes and Cilostazol therapy in patient management
    Medical condition: Intermittent claudication
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-002110-38 Sponsor Protocol Number: 20050506 Start Date*: 2007-09-12
    Sponsor Name:Dept of ped hem/onc
    Full Title: RCT of oral paracetamol for procedural anxiety, distress and pain in children with cancer
    Medical condition: Pain relif before needle insertion in a subcoutanously implanted iv port in children with cancer
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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