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Clinical trials for ,DHF

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
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    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    6 result(s) found for: ,DHF. Displaying page 1 of 1.
    EudraCT Number: 2006-002605-31 Sponsor Protocol Number: Aldo-DHF Start Date*: 2007-02-01
    Sponsor Name:Georg-August-Universität Göttingen
    Full Title: ALDOSTERONE RECEPTOR BLOCKADE IN DIASTOLIC HEART FAILURE A double-blind, randomised, placebo-controlled, parallel group study to determine the effects of spironolactone on exercise capacity and dia...
    Medical condition: Diastolic Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    8.1 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-002546-49 Sponsor Protocol Number: SCP-01-001 Start Date*: 2014-10-03
    Sponsor Name:scPharmaceuticals Inc
    Full Title: A single center, randomized, open-label, cross-over exploratory study to evaluate the pharmacodynamic and pharmacokinetic response to a subcutaneous administration or oral administration of furosem...
    Medical condition: Fluid overload in heart failure
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-018436-41 Sponsor Protocol Number: Bay 63-2521/14554 Start Date*: 2010-05-11
    Sponsor Name:Bayer HealthCare AG
    Full Title: Acute hemoDynamic effects of RIociguat (BAY 63-2521) in patients with puLmonary hypertension Associated with diasTolic heart failurE (DILATE 1): A randomized, double-blind, placebo-controlled, sin...
    Medical condition: Pulmonary hypertension associated with diastolic heart failure
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10037405 Pulmonary hypertension primary LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended) CZ (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-003601-25 Sponsor Protocol Number: DROP-PIP Start Date*: 2014-03-28
    Sponsor Name:Charité Universitätsmedizin Berlin
    Full Title: A multicenter, Double-blind, RandOmised, two arm Parallel group trial to determine the effects of torasemide versus furosemide on one marker (PIP) of cardiac fibrosis in patient with Diastolic Hear...
    Medical condition: Diastolic heart failure and diabetes mellitus type II
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-003146-75 Sponsor Protocol Number: BETA3_LVH Start Date*: 2016-03-14
    Sponsor Name:Université catholique de Louvain (UCL)
    Full Title: A multi-centre randomized, placebo-controlled trial of mirabegron, a new beta3-adrenergic receptor agonist on the progression of left ventricular mass and diastolic function in patients with struct...
    Medical condition: Structural heart disease at high risk for progressive hypertrophic cardiac remodeling at risk of developing HFpEF (heart failure with preserved ejection fraction).
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004849 10019290 Heart insufficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed) PT (Completed) GR (Completed) PL (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-003070-26 Sponsor Protocol Number: BLO K026 (D-CAN-546) Start Date*: 2008-08-13
    Sponsor Name:Takeda Pharma GmbH
    Full Title: Candesartan “added” therapy for treatment optimization of symptomatic heart failure with diastolic dysfunction in diabetic and hypertensive patients. A randomized, placebo-controlled, double-blind,...
    Medical condition: Symptomatic heart failure with diastolic dysfunction in diabetic and hypertensive patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019279 Heart failure LLT
    9.1 10052337 Diastolic dysfunction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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