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Clinical trials for ADAM

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44364   clinical trials with a EudraCT protocol, of which   7388   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    24 result(s) found for: ADAM. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2005-001411-22 Sponsor Protocol Number: ADAM SPECT 3792 Start Date*: 2006-02-15
    Sponsor Name:University School of Medicine Hannover (MHH), represented by the chairmanship
    Full Title: Serotonin-Transporter Binding in Tourette-Syndrome and Obsessive-Compulsive Disorder before and during Treatment with SRI: a I-123-ADAM-SPECT-Study
    Medical condition: Obsessive compulsive disorder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-000870-51 Sponsor Protocol Number: CMCS240281 Start Date*: 2013-02-25
    Sponsor Name:Unidad de Gestión Clínica de Endocrinología y Nutrición
    Full Title: RANDOMIZED CLINICAL TRIAL TO ASSESS THE EFFICACY OF TESTOSTERONE UNDECANOATE, METFORMIN, OR THE COMBINATION OF BOTH, FOR THE TREATMENT OF ISOLATED HYPOGONADOTROPIC HYPOGONADISM AND ERECTILE DYSFUNC...
    Medical condition: Isolated hypogonadotropic hypogonadism related to obesity
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004592-35 Sponsor Protocol Number: 6836 Start Date*: 2010-06-16
    Sponsor Name:Barts Health NHS Trust
    Full Title: A Randomised Stratified Multicentre Phase II Clinical Trial of Single-Agent ADI-PEG 20 (Pegylated Arginine Deiminase) in Patients with Malignant Pleural Mesothelioma.
    Medical condition: Mesothelioma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-004406-93 Sponsor Protocol Number: PDD-PC-01 Start Date*: 2007-05-29
    Sponsor Name:Klinikum der Universität München
    Full Title: Photodynamische Diagnostik mit 5-Aminolävulinsäure zur Beurteilung der intraoperativen Absetzungsränder im Rahmen der radikalen Prostatovesikulektomie bei Patienten mit einem Prostatakarzinom
    Medical condition: Patients with prostate carinoma who will undergo radical prostatectomy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036921 Prostate carcinoma LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-003982-21 Sponsor Protocol Number: P080402 Start Date*: 2010-06-10
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Etude des transporteurs de la dopamine et de la sérotonine en imagerie TEMP utilisant les radiopharmaceutiques 123I-FP-CIT (datscan) and 123 I-ADAM dans la sclérose latérale amyotrophique et dans u...
    Medical condition: Patients présentant une SLA et volontaires sains
    Disease: Version SOC Term Classification Code Term Level
    8.1 10002026 Amyotrophic lateral sclerosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2017-000842-23 Sponsor Protocol Number: AdAM_2017 Start Date*: 2018-02-19
    Sponsor Name:Medical University Innsbruck
    Full Title: Adjuvante Imiquimod Therapie zur Senkung der Rezidivrate nach operativer Therapie bei analen HPV-Läsionen
    Medical condition: anal HPV-lesions
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-001224-33 Sponsor Protocol Number: COV-HCQ Start Date*: 2020-03-25
    Sponsor Name:Universitätsklinikum Tübingen
    Full Title: Randomized controlled trial of hydroxychloroquine versus placebo for the treatment of adult patients with acute coronavirus disease 2019 – COVID-19
    Medical condition: Acute coronavirus disease 2019
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10053983 Corona virus infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-001849-39 Sponsor Protocol Number: NETs-C19 Start Date*: 2020-05-18
    Sponsor Name:Region Skåne
    Full Title: Aerosolized DNase I for the treatment of severe respiratory failure in COVID-19 - a phase 2, randomized controlled trial
    Medical condition: SARS-coronavirus-2 infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-011881-27 Sponsor Protocol Number: ADAM Start Date*: Information not available in EudraCT
    Sponsor Name:University Medical Center of the Johannes Gutenberg-University Mainz
    Full Title: Changes of cerebral spinal fluid APPSα levels under oral therapy with acitretin 30 mg daily in patients with mild to moderate Alzheimer’s disease: a multicenter prospective randomised placebo-contr...
    Medical condition: Alzheimer’s disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10001896 Alzheimer's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-002612-52 Sponsor Protocol Number: LUCAS Start Date*: 2021-02-19
    Sponsor Name:Department of Endocrinology, Rigshospitalet
    Full Title: A randomized, double-blinded, clinical, placebo-controlled trial on the effects of therapy with Letrozole and hUman Choriongonadotropin in male hypogonadism induced by illicit use of Anabolic andro...
    Medical condition: Male hypogonadism related to illicit use of anabolic androgenic steroids
    Disease: Version SOC Term Classification Code Term Level
    20.0 10014698 - Endocrine disorders 10058359 Hypogonadism PT
    21.0 10038604 - Reproductive system and breast disorders 10021926 Infertility PT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-005179-10 Sponsor Protocol Number: ISS16694 Start Date*: 2015-07-27
    Sponsor Name:Charalampos Vlachopoulos
    Full Title: Effect of long-term testosterone replacement therapy on arterial stiffness and endothelial function in male patients with hypogonadism
    Medical condition: Male patients with hypogonadism
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-001512-26 Sponsor Protocol Number: COMIHY Start Date*: 2020-04-22
    Sponsor Name:Universitätsklinikum Tübingen
    Full Title: Hydroxychloroquine for the treatment of mild COVID-19 disease
    Medical condition: Acute coronavirus disease 2019
    Disease: Version SOC Term Classification Code Term Level
    23.0 100000004862 10053983 Corona virus infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-003559-39 Sponsor Protocol Number: 2011PP02 Start Date*: 2013-10-01
    Sponsor Name:The University of Dundee [...]
    1. The University of Dundee
    2. NHS TAYSIDE
    Full Title: Allopurinol and cardiovascular outcomes in patients with ischaemic heart disease (ALL-HEART)
    Medical condition: Ischaemic Heart Disease (IHD), angina or myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004849 10023024 Ischaemic heart disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2021-004254-37 Sponsor Protocol Number: 000400 Start Date*: 2022-06-27
    Sponsor Name:Ferring Pharmaceuticals A/S
    Full Title: A randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of FE 999049 for treatment of men with idiopathic infertility
    Medical condition: Idiopathic male infertility (including oligoasthenozoospermia)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038604 - Reproductive system and breast disorders 10021929 Infertility male PT
    Population Age: Adults Gender: Male
    Trial protocol: SE (Trial now transitioned) DE (Trial now transitioned) ES (Trial now transitioned) DK (Trial now transitioned) BE (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-004641-16 Sponsor Protocol Number: RG_18-272 Start Date*: 2020-02-14
    Sponsor Name:University of Birmingham
    Full Title: Letrozole or Clomifene, with or without metformin, for ovulation induction in women with polycystic ovary syndrome: a 2x2 factorial design randomised trial (The LOCI trial)
    Medical condition: Ovulation induction for women suffering from polycystic ovary syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004860 10002658 Anovulation LLT
    20.0 100000004872 10021935 Infertility, female, associated with anovulation LLT
    21.1 100000004872 10036050 Polycystic ovary LLT
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10049550 Live birth PT
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10049550 Live birth PT
    Population Age: Under 18, Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2023-000156-38 Sponsor Protocol Number: 20230123SE Start Date*: 2023-05-04
    Sponsor Name:Semmelweis University, Department of Internal Medicine and Oncology
    Full Title: Value-based health economic comparative study of subcutaneous and intravenous trastuzumab-pertuzumab for HER-2 positive metastatic breast cancer based on patient reported outcomes.
    Medical condition: HER-2 positive advanced breast cancer, locally unresectable or metastatic breast cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10057654 Breast cancer female PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006198 Breast cancer recurrent PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006201 Breast cancer stage III PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006202 Breast cancer stage IV PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006187 Breast cancer PT
    20.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10055113 Breast cancer metastatic PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003579-16 Sponsor Protocol Number: BIOMIN Start Date*: 2021-04-07
    Sponsor Name:BIOMIN, a. s.
    Full Title: Multicenter, randomized, 52-week trial to determine the efficacy, adherence, safety, and tolerability of natural calcium and vitamin D3 and vitamin K2 supplementation, respectively, in postmenopaus...
    Medical condition: Osteopenia
    Disease: Version SOC Term Classification Code Term Level
    24.0 100000004861 10021059 Hypophosphatemia LLT
    20.1 100000004867 10021689 Increased thirst LLT
    20.0 10017947 - Gastrointestinal disorders 10016766 Flatulence PT
    21.1 10017947 - Gastrointestinal disorders 10081649 Rebound gastric hypersecretion LLT
    20.0 10017947 - Gastrointestinal disorders 10045304 Ulcer gastric LLT
    20.0 10017947 - Gastrointestinal disorders 10010774 Constipation PT
    20.0 10017947 - Gastrointestinal disorders 10004222 Belching LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SK (Completed) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004742-42 Sponsor Protocol Number: IFCT-1802 Start Date*: 2019-08-29
    Sponsor Name:IFCT
    Full Title: A phase II single-arm trial evaluating safety and efficacy of Durvalumab in ECOG Performance Status 2-3, treatment-naive, patients with stage IV Non-Small Cell Lung Cancer (NSCLC) and high PD-L1 t...
    Medical condition: Patient with a non small cell lung cancer and a poor general status
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029522 Non-small cell lung cancer stage IV PT
    20.1 100000004867 10057364 Reduced general condition LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2005-004451-35 Sponsor Protocol Number: MRTSH01505 Start Date*: 2007-03-13
    Sponsor Name:Genzyme Europe BV
    Full Title: Study to Evaluate the Dose, Safety and Effectiveness of Modified-Release Recombinant Human Thyroid Stimulating Hormone (MRrhTSH) When Used in Conjunction with Radioiodine for the Treatment of Multi...
    Medical condition: Nodular goiter are clinically recognizable enlargements of the thyroid gland characterized by excessive growth and structural and or functional transformation of one or several areas within the nor...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10043808 Thyrotropin LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) DK (Completed) FR (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-004329-10 Sponsor Protocol Number: UKM17_0018 Start Date*: 2020-07-09
    Sponsor Name:Westfälische Wilhelms-Universität Münster c/o Universitätsklinikum Münster, Geschäftsbereich Recht u. Drittmittel
    Full Title: A Randomized, open-label, Phase 2 Study of Adjuvant Apalutamide or Standard of Care in Subjects with High-risk, Localized or Locally Advanced Prostate Cancer After Radical Prostatectomy
    Medical condition: High risk adenocarcinoma of the prostate after radical prostatectomy (RPE)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060862 Prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Trial now transitioned) AT (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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