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Clinical trials for AIDS

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    294 result(s) found for: AIDS. Displaying page 1 of 15.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2006-006047-30 Sponsor Protocol Number: ema2_LNH e HIV Start Date*: 2008-10-09
    Sponsor Name:AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
    Full Title: First line treatment in HIV-related diffuse large cell non Hodgkin Lymphoma at ''high risk'', including early consolidation with high dose chemotherapy and autologous peripheral blood stem cell tra...
    Medical condition: diffuse large cell lymphoma HIV infection related
    Disease: Version SOC Term Classification Code Term Level
    6.1 10025312 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-024510-57 Sponsor Protocol Number: TRIANT-TE Start Date*: 2011-03-14
    Sponsor Name:Fundació Lluita contra la SIDA
    Full Title: Estudio Randomizado, Prospectivo, Controlado, para Comparar la Eficacia y Seguridad de Dos Estrategias Farmacológicas Diferentes sobre la Alteración Neurocognitiva en la Infección por VIH. Estudio ...
    Medical condition: Alteración neurocognitiva en la infección por VIH.
    Disease: Version SOC Term Classification Code Term Level
    13 10012277 Demencia por enfermedad por VIH LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2016-003741-29 Sponsor Protocol Number: MARAND-X Start Date*: 2017-04-05
    Sponsor Name:A.S.L. TO 2
    Full Title: MARAND-X Study: MARaviroc-based Treatment Switch in HIV-positive Patients with HAND: Consequences of Reducing Antiretroviral-associated NeurotoXicity
    Medical condition: HIV-infection, HIV-associated neurocognitive disorders
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004862 10001516 AIDS-dementia complex LLT
    20.0 100000004848 10002725 Anti-HIV positive LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-023264-40 Sponsor Protocol Number: SNC Start Date*: 2010-10-21
    Sponsor Name:AZIENDA OSPEDALIERA S. GERARDO DI MONZA
    Full Title: Efficacy in the central nervous system (CNS) of two combination regimens with different penetration rank in HIV-positive na�ve patients
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049072 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-000669-21 Sponsor Protocol Number: ML18243 Start Date*: 2005-04-26
    Sponsor Name:ROCHE
    Full Title: Pilot study of HIV Viral slope in naive patients treated with Enfuvirtide (ENF) based therapy compared to current standard treatment.
    Medical condition: advanced HIV management
    Disease: Version SOC Term Classification Code Term Level
    6.1 10000565 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-022775-57 Sponsor Protocol Number: JF002 Start Date*: 2011-06-09
    Sponsor Name:Guy's and St Thomas' NHS Foundation Trust
    Full Title: Effects of Vitamin D supplementation on Vitamin D levels and immune activation in HIV infected individuals on antiretroviral therapy-A pilot study.
    Medical condition: HIV infected patients with vitamin D defficiency
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10020189 HIV test positve LLT
    14.1 10022891 - Investigations 10020180 HIV positive LLT
    14.1 10021881 - Infections and infestations 10020160 HIV disease LLT
    14.1 10022891 - Investigations 10020181 HIV positve LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-003099-35 Sponsor Protocol Number: SA1001 Start Date*: 2011-11-11
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: Phase I/II study of oral MEK inhibitor Selumetinib (AZD6244 Hyd-Sulphate) in Combination with Highly Active Anti-Retroviral Therapy (HAART) in AIDS-associated Kaposi’s sarcoma (KS).
    Medical condition: AIDS-associated Kaposi's sarcoma
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10023286 Kaposi's sarcoma AIDS related PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004137-91 Sponsor Protocol Number: Gesida92016 Start Date*: 2018-01-23
    Sponsor Name:Fundacion SEIMC-GESIDA
    Full Title: A single-arm, open-label, multicenter phase IV trial to evaluate the efficacy and safety of elvitegravir / cobicistat / emtricitabine / tenofovir alfa-namide as first-line treatment in naïve patien...
    Medical condition: AIDS
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10001509 AIDS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006297-23 Sponsor Protocol Number: 06/Q0701/34 Start Date*: 2007-06-12
    Sponsor Name:Guy's & St Thomas' NHS Foundation Trust
    Full Title: A study of the pharmacokinetics of new formulation lopinavir/ritonavir in the genital tract and plasma of HIV infected women in pregnancy
    Medical condition: HIV during pregnancy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10020180 HIV positive LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015647-16 Sponsor Protocol Number: ANV-09-008 Start Date*: 2010-01-28
    Sponsor Name:GUIDE Clinic, St James's Hospital
    Full Title: The pharmacokinetics of once daily Kaletra and methadone in a population of HIV positiive drug users.
    Medical condition: HIV-1 Positive Injection Drug Users
    Disease: Version SOC Term Classification Code Term Level
    12.0 10020180 HIV positive LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-000950-30 Sponsor Protocol Number: HPH116-104-PoC-2007 Start Date*: 2007-09-05
    Sponsor Name:H-PHAR,sa
    Full Title: Estudio piloto, doble ciego, aleatorizado, controlado con placebo, de dosis repetida, para la evaluación de la seguridad y la eficacia antiviral de HPH116 en pacientes infectados por VIH-1 que no h...
    Medical condition: Enfermedad medica investigada = SIDA (pacientes infectados con VIH-1) Pacientes infectados por VIH-1 que no hayan recibido tratamiento previo recibirán 600 mg ó 1200 mg de HPH116 dos veces al día f...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020180 HIV positive LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005039-40 Sponsor Protocol Number: 2006-005039-40HIVD001 Start Date*: 2007-02-16
    Sponsor Name:Calcium and Bone Metabolic Unit Copenhange University Hospital Hvidovre
    Full Title: Vitamin D status hos patienter med HIV infektion - Intervention with vitamin D - a pilot study
    Medical condition: It has been shown in our clinic that many patients with HIV infektion have vitamin D deficiency and it is the aim to investigate the benefits of correcting this vitamin D deficiency on bone metabol...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10020180 HIV positive LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006439-12 Sponsor Protocol Number: INSIGHT001:STARTDAIDSID#10619 Start Date*: 2009-05-25
    Sponsor Name:Regents of the University of Minnesota
    Full Title: Strategic Timing of AntiRetroviral Treatment(START)
    Medical condition: HIV Infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) FI (Completed) ES (Completed) DE (Completed) GB (GB - no longer in EU/EEA) GR (Completed) IT (Completed) SE (Completed) PT (Completed) IE (Completed) EE (Completed) NO (Completed) AT (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2010-022413-26 Sponsor Protocol Number: IDEAL-Study Start Date*: 2011-07-29
    Sponsor Name:University Medical Center Hamburg-Eppendorf
    Full Title: Immediate versus deferred antiretroviral therapy in HIV-infected patients presenting with acute AIDS-defining events (IDEAL-Study)
    Medical condition: Patients in late stage of HIV-infection, treatment naive or without ART for the last 6 month with an acute AIDS-defining illness, namely PCP or TE.
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004862 10001509 AIDS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-000307-26 Sponsor Protocol Number: CeTMAd-VIH-2014 Start Date*: 2016-06-09
    Sponsor Name:Iniciativa Andaluza en Terapias Avanzadas-Fundación Pública Andaluza Progreso y Salud
    Full Title: Clinical trial Phase I/II, test of concept, double blind, randomized, controlled with placebo, to evalue the safety and efficiency of the treatment with expanded adult mesenchymal stem cells from a...
    Medical condition: Infection for HIV with controlled viral load and immunological discordant response
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004862 10001509 AIDS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2016-004646-29 Sponsor Protocol Number: GESIDA9016 Start Date*: 2017-05-31
    Sponsor Name:Fundación SEIMC-GESIDA
    Full Title: A phase IV open- label, randomized and pilot clinical trial, designed to evaluate the potential neurotoxicity of dolutegravir/lamivudine/abacavir in neurosymptomatic HIV patients and their reversi...
    Medical condition: HIV
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004862 10001509 AIDS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002818-38 Sponsor Protocol Number: ML 19326 Start Date*: 2005-07-21
    Sponsor Name:ROCHE
    Full Title: ESPrES 500 - Evaluation of the safety profile of the new 500 mg film-coated tablet (FCT) formulation of boosted saquinavir (Invirase 500 mg) in HIV-1 infected patients
    Medical condition: HIV-! / AIDS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000565 Acquired immunodeficiency syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-001158-82 Sponsor Protocol Number: GESIDA10418 Start Date*: 2018-09-21
    Sponsor Name:Fundación SEIMC-GESIDA
    Full Title: Phase IV, Open Label, Randomized, Clinical Trial to Evaluate the Reversibility of abacavir/lamivudine/dolutegravir CNS-Related Neurotoxicity After Switching to tenofovir alafenamide/emtricitabine/d...
    Medical condition: HIV
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10001509 AIDS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2005-003026-26 Sponsor Protocol Number: ARL - GT 2005 Start Date*: 2008-09-15
    Sponsor Name:University Medical Center Hamburg-Eppendorf
    Full Title: High-dose chemotherapy with transplantation of gene-modified haematopoietic stem cells for HIV-positive patients with malignant diseases indicating an HSCT
    Medical condition: HIV-positive patients with any malignant disease of the haematopoietic system indicating haematopoietic stem cell transplantation (autologous or allogeneic)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10061624 AIDS related complication LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-007882-19 Sponsor Protocol Number: MI2-STAR2-2006 Start Date*: 2006-10-09
    Sponsor Name:AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
    Full Title: A pilot, randomized trial to evaluate the lipid profile after antiretroviral regimens including nevirapine or atazanavir boosted with ritonavir in HIV-positive patients naive for antiretrovirals
    Medical condition: immunodefic syndrome - patients naive antiretroviral therapy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000565 Acquired immunodeficiency syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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