Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Acid Reflux

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44260   clinical trials with a EudraCT protocol, of which   7346   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    116 result(s) found for: Acid Reflux. Displaying page 1 of 6.
    1  2  3  4  5  6  Next»
    EudraCT Number: 2008-004633-24 Sponsor Protocol Number: PCT Start Date*: 2008-10-23
    Sponsor Name:Women's and Children's Hospital
    Full Title: A trial of position control therapy (PCT) for treatment of infantile gastro-oesophageal reflux
    Medical condition: gastro-oesophageal reflux related symptoms
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017884 Gastrooesophageal reflux LLT
    9.1 10017885 Gastrooesophageal reflux disease LLT
    9.1 10017924 Gastroesophageal reflux LLT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013080-19 Sponsor Protocol Number: 27538 Start Date*: 2010-03-31
    Sponsor Name:AMC
    Full Title: Prokinetics to alter the position of the gastric acid pocket in Gastro Esophageal Reflux Disease
    Medical condition: gastro-esophageal reflux disease (GERD)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000479 Acid reflux (oesophageal) LLT
    9.1 10017884 Gastrooesophageal reflux LLT
    9.1 10017885 Gastrooesophageal reflux disease LLT
    9.1 10038262 Reflux esophagitis LLT
    9.1 10020024 Hiatal hernia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-006081-29 Sponsor Protocol Number: Rimonaslok Start Date*: 2008-10-21
    Sponsor Name:UZLeuven
    Full Title: INFLUENCE OF RIMONABANT ON LOWER ESOPHAGEAL FUNCTION IN HEALTHY VOLUNTEERS
    Medical condition: none; this is a physiological study to investigate the influence of CB1 receptor antagonism by rimonabant (normally used for the treatment of obesity) on esophageal function, i.e. esophageal contr...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017924 Gastroesophageal reflux LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004155-35 Sponsor Protocol Number: A7421007 Start Date*: 2005-12-01
    Sponsor Name:Pfizer Limited
    Full Title: A randomized, double blind, parallel group study to examine the effect of multiple doses of CJ-040,714 on distal esophageal acid exposure an patients with erosive gastro-esophageal reflux disease (...
    Medical condition: Gastro-Esophageal Reflux Disease (GERD)
    Disease: Version SOC Term Classification Code Term Level
    8.0 10017885 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004501-25 Sponsor Protocol Number: D9120C00020 Start Date*: 2006-12-18
    Sponsor Name:AstraZeneca AB
    Full Title: A double-blind, placebo controlled, randomized, two centre phase IIa pharmacodynamic cross-over study to assess the effect of AZD3355, 65 mg bid, on transient lower esophageal sphincter relaxations...
    Medical condition: Gastroesophageal Reflux Disease (GERD)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10017924 Gastroesophageal reflux LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000926-30 Sponsor Protocol Number: BY1023/M3-343 Start Date*: Information not available in EudraCT
    Sponsor Name:ALTANA Pharma AG
    Full Title: Investigation of clinical endpoints for treatment-induced gastroesophageal reflux disease (GERD) symptom changes
    Medical condition: gastroesophageal reflux disease
    Disease: Version SOC Term Classification Code Term Level
    8.1 10017885 Gastrooesophageal reflux disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2010-018608-98 Sponsor Protocol Number: D3830C00001 Start Date*: 2010-06-09
    Sponsor Name:AstraZeneca AB
    Full Title: A double-blind, randomized, placebo-controlled, two-centre, phase IIa pharmacodynamic cross-over study to assess the effect of AZD2516 on the total number of reflux episodes in healthy male volunteers
    Medical condition: Gastroesophageal Reflux Disease (GERD)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10017924 Gastroesophageal reflux LLT
    Population Age: Adults Gender: Male
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-002646-35 Sponsor Protocol Number: M0003-C101 Start Date*: 2008-08-06
    Sponsor Name:Movetis NV
    Full Title: A prospective phase 1, single-dose, open-label, multi-centre clinical trial to evaluate the pharmacokinetics and safety of M0003 in young children aged between 1 and 36 months.
    Medical condition: Intended indication for product under development: Infant gastro-oesophageal reflux disease (GORD)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017885 Gastrooesophageal reflux disease LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) NL (Not Authorised) GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-003541-16 Sponsor Protocol Number: D9120C00011 Start Date*: 2006-11-07
    Sponsor Name:AstraZeneca AB
    Full Title: A randomized, double-blind, placebo controlled, multi-centre, phase IIA study to assess the effect on GERD symptoms, pharmacokinetics, safety and tolerability of four weeks treatment with AZD3355 6...
    Medical condition: Gastroesophageal Reflux Disease (GERD)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10017924 Gastroesophageal reflux LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) NO (Completed) NL (Completed) DE (Completed) HU (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017229-20 Sponsor Protocol Number: KCT 27/2009 – PAN-STAR/PL Start Date*: 2010-06-24
    Sponsor Name:KRKA-POLSKA Sp. z o.o.
    Full Title: Efficacy and safety of PANtoprazole in the treatment and SympTom relief in patients with gAstRoesophageal reflux disease (GERD) – PAN-STAR
    Medical condition: gastroesophageal reflux disease (GERD)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10066874 Gastroesophageal reflux disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2004-002370-39 Sponsor Protocol Number: D9614C00097 Start Date*: 2004-12-02
    Sponsor Name:ASTRAZENECA
    Full Title: A Phase III, Multicentre, Randomized, Double-blind Parallel-group Study to Evaluate the Safety and Clinical Outcome of Once Daily Esomeprazole for the Treatment of Gastroesophageal Reflux Disease ...
    Medical condition: Gastroesophageal Reflux Disease GERD
    Disease: Version SOC Term Classification Code Term Level
    6.1 10017885 PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2008-000452-27 Sponsor Protocol Number: RABGRD1003 Start Date*: 2008-05-16
    Sponsor Name:Janssen-Cilag International N.V.
    Full Title: A Pharmacokinetic, Pharmacodynamic and Safety Study of Single and Multiple Doses of Rabeprazole in Pediatric Subjects with GERD 1 to 11 Months old, Inclusive
    Medical condition: Pediatric subjects with GERD
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018203 GERD LLT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-004232-29 Sponsor Protocol Number: UZBLANREOTIDE01 Start Date*: 2014-01-02
    Sponsor Name:UZ Brussel
    Full Title: A phase II proof of concept study to evalute the efficacy and safety of deep subcutaneous lanreotide Autogel 120 mg / 28 days on symptoms and healing of the esophageal and gastric mucosa in patient...
    Medical condition: patients with persistent endoscopic reflux in spite of maximal medical therapy with PPI 2 x 40 mg pantoprazole before breakfast and dinner and 300 mg of H2 blocker ranitidine at bedtime AND continu...
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004856 10017924 Gastroesophageal reflux LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019563-11 Sponsor Protocol Number: RB10001 Start Date*: 2010-06-01
    Sponsor Name:RECKITT BENCKISER HEALTHCARE
    Full Title: Etude de non-infériorité de l’efficacité de Gaviscon suspension buvable en flacon versus Oméprazole 20mg sur le pyrosis chez des patients ayant un RGO dont l’épisode actuel n’est pas traité.
    Medical condition: Patient volontaire présentant un épisode de RGO non traité et venant consulter en médecine générale.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10017924 Gastroesophageal reflux LLT
    12.1 10017885 Gastrooesophageal reflux disease LLT
    12.1 10017933 Gastrointestinal atonic and hypomotility disorders NEC HLT
    12.1 10063655 Erosive oesophagitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2023-000179-10 Sponsor Protocol Number: VPED-102 Start Date*: 2023-10-06
    Sponsor Name:Phathom Pharmaceuticals, Inc.
    Full Title: A Phase 1, Randomized, Parallel-group, Open-label, Multicenter Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of Vonoprazan (10 or 20 mg Once Daily) in Adolescents With Symptom...
    Medical condition: symptomatic gastroesophageal reflux disease
    Disease: Version SOC Term Classification Code Term Level
    20.1 10017947 - Gastrointestinal disorders 10017885 Gastrooesophageal reflux disease PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-004856-11 Sponsor Protocol Number: BY1023/DE004 Start Date*: 2006-07-12
    Sponsor Name:ALTANA Pharma AG
    Full Title: Symptom reduction in hospitalized patients suffering from symptomatic non-erosive or erosive gastroesophageal reflux disease treated with pantoprazole 20 or 40 mg o.d. for 7 days
    Medical condition: Symptomatic non-erosive reflux disease (NERD) or erosive gastroesophageal reflux disease (GERD)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10017885 Gastrooesophageal reflux disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-003228-42 Sponsor Protocol Number: VPED-103 Start Date*: 2024-09-09
    Sponsor Name:Phathom Pharmaceuticals, Inc
    Full Title: A Phase 1, Randomized, Parallel-group, Open-label, Multicenter Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of Vonoprazan (10 or 20 mg Once Daily) in Children Aged ≥ 6 to < 1...
    Medical condition: symptomatic gastroesophageal reflux disease
    Disease: Version SOC Term Classification Code Term Level
    20.1 10017947 - Gastrointestinal disorders 10017885 Gastrooesophageal reflux disease PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-002867-19 Sponsor Protocol Number: D9612L00111 Start Date*: 2006-12-15
    Sponsor Name:AstraZeneca S.A.S
    Full Title: Evaluation de l’efficacité de 3 stratégies de prise en charge au long cours des symptômes de reflux gastro-oesophagien en médecine générale : étude multicentrique, randomisée, en ouvert, réalisée e...
    Medical condition: Reflux Gastro Oesophagien
    Disease: Version SOC Term Classification Code Term Level
    8.1 10017885 Gastrooesophageal reflux disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2012-001160-29 Sponsor Protocol Number: SH-NEC-0002 Start Date*: 2012-03-08
    Sponsor Name:AstraZeneca AB
    Full Title: An Open Single-centre Study on the Pharmacokinetics and Pharmacodynamics of Esomeprazole After Once Daily Oral Administration for 7 Days in Preterm Infants and Neonates
    Medical condition: Gastraesdophageal Reflux Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10018203 GERD LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2007-003067-46 Sponsor Protocol Number: FZ07/04 Start Date*: 2007-10-03
    Sponsor Name:Flevoziekenhuis
    Full Title: Effect of domperidone and omeprazole in gastro-oesophageal reflux disease in infants between 0 and 2 years.
    Medical condition: Gastro-oesophageal reflux disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017924 Gastroesophageal reflux LLT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  4  5  6  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA