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Clinical trials for Active ingredients

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    43 result(s) found for: Active ingredients. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2018-000685-12 Sponsor Protocol Number: MC2-01-C6 Start Date*: Information not available in EudraCT
    Sponsor Name:MC2 Therapeutics Ltd
    Full Title: A Multicentre, Open-label, Single-group Maximal Use Trial, Evaluating the Safety and Pharmacokinetic Profile of the Active Ingredients and their Metabolites after application of MC2-01 Cream in Ado...
    Medical condition: Extensive Psoriasis Vulgaris
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10050576 Psoriasis vulgaris LLT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) CZ (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2013-001974-11 Sponsor Protocol Number: HEPATOTEST Start Date*: 2013-08-29
    Sponsor Name:INSTITUTO DE INVESTIGACION SANITARIA LA FE
    Full Title: PILOT TRIAL FOR THE EVALUATION OF HEPATOTEST IN PREOPERATIVE ASSESSMENT IN LIVER FUNCTION.
    Medical condition: Patients with liver metastases (mainly colorectal cancer) who will be undergoing major hepatic resection (3 or more liver segments) which have been treated with neoadjuvant chemotherapy.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000537-24 Sponsor Protocol Number: IIS-HEPA-TEST Start Date*: 2014-07-16
    Sponsor Name:INSTITUTO DE INVESTIGACION SANITARIA LA FE
    Full Title: Pilot clinical trial phase I / IIa to determine condition, low dose and effectiveness of liver function tests (Hepatotest)
    Medical condition: Hepatic Function.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014441-93 Sponsor Protocol Number: X-03030-3277 Start Date*: 2010-08-16
    Sponsor Name:MEDA Pharma GmbH & Co. KG
    Full Title: Clinical trial to assess the efficacy of the fixed combination product Tepilta® in the treatment of radiation-induced oesophagitis compared to its active ingredients oxetacaine and antacids, and t...
    Medical condition: Radiation-induced oesophagitis
    Disease: Version SOC Term Classification Code Term Level
    19.1 10022117 - Injury, poisoning and procedural complications 10048899 Radiation oesophagitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-002081-12 Sponsor Protocol Number: AHV-18-A Start Date*: 2019-12-19
    Sponsor Name:Amryt Research Ltd.
    Full Title: An exploratory randomized, intra-individual controlled trial of the cutaneous healing properties of Petrolatum versus the vehicle for Oleogel-S10 versus no treatment when applied topically to me...
    Medical condition: Not applicable, as healthy volunteers will be recruited, who will receive mechanically induced partial thickness wounds.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-002358-26 Sponsor Protocol Number: AHV-18-B Start Date*: 2020-09-29
    Sponsor Name:Amryt Research Ltd.
    Full Title: A randomised, intra-individual controlled trial of the cutaneous healing properties of petrolatum versus the vehicle for Oleogel-S10 when applied topically to mechanically induced partial thickness...
    Medical condition: Not applicable, as healthy volunteers will be recruited, who will receive mechanically induced partial thickness wounds.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003829-31 Sponsor Protocol Number: 05DCz/FHp11 Start Date*: 2006-01-18
    Sponsor Name:IBSA Institut Biochimique S.A.
    Full Title: A multicentre, prospective, double-blind, in parallel groups randomised, versus placebo and versus reference product controlled, confirmatory clinical trial of the efficacy and tolerance of Flector...
    Medical condition: mild-to-moderate contusions
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000911-27 Sponsor Protocol Number: V00096 CR 205 (ORF) Start Date*: 2007-09-03
    Sponsor Name:ORFAGEN
    Full Title: Evaluation of the protection activity of microfine Ti02, pigmentary Ti02 and bisoctrizole and their combinations in voluntary patients with idiopathic solar urticaria (SU): phase II photoprovocatio...
    Medical condition: Idiopathic Solar Urticaria (SU)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-000386-31 Sponsor Protocol Number: OPTO-01-2015(pROSAM) Start Date*: Information not available in EudraCT
    Sponsor Name:AZIENDA OSPEDALIERA DI PADOVA
    Full Title: Role of SAMITAL in pediatric age ¿ a feasibility study in children with/or at risk of oral mucositis due to chemotherapy and/or radiotherapy
    Medical condition: Children affected or at risk of oral mucositis from chemoterapy and/or radiotherapy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029104 Neoplasms benign, malignant and unspecified (incl cysts and polyps) SOC
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024045-69 Sponsor Protocol Number: TH1017 Start Date*: 2011-01-11
    Sponsor Name:Reckitt Benckiser Healthcare
    Full Title: A multi centre, randomised, double blind, single dose parallel group, placebo controlled study to investigate the efficacy of Strepsils Plus and Strepsils Extra in the treatment of sore throat due ...
    Medical condition: Sore throat due to upper respiratory tract infection
    Disease: Version SOC Term Classification Code Term Level
    12.1 10041367 sore throat LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-001056-22 Sponsor Protocol Number: NDOL-001-2016 Start Date*: 2016-08-24
    Sponsor Name:Medical Univerity Vienna
    Full Title: Neodolpasse® Infusion Solution versus diclofenac 75 mg infusion in the treatment of postoperative pain after elective knee surgery - an exploratory placebo-controlled clinical study to investigate ...
    Medical condition: major elective knee surgery (cruciate ligament surgery)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-005672-13 Sponsor Protocol Number: CR-DER-3-07 (07E0274PH) Start Date*: 2007-12-28
    Sponsor Name:PALAU PHARMA SA
    Full Title: DOUBLE-BLIND STUDY, RANDOMISED, ACTIVE AND PLACEBO CONTROLLED TO ASSESS THE CLINICAL EFFICACY, SKIN TOLERABILITY AND PHARMACOLOGICAL ACTIVITY OF UR-1505 OINTMENT AT THREE DIFFERENT STRENGHTS IN PAT...
    Medical condition: Patients suffering from psoriasis with at least two eligible psoriatic plaques on equivalent topographic areas (arms, legs or trunk)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10037153 Psoriasis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002190-22 Sponsor Protocol Number: Phlogosol_2013/01 Start Date*: 2014-03-26
    Sponsor Name:PannonPharma Ltd.
    Full Title: Therapeutic clinical trial of three types of “Phlogosol concentrate for gargle” products, comparing their efficacy in reducing different inflammations of the oral cavity. (Changing the active ing...
    Medical condition: Cold with sore throat, acute stomatitis, chronic pharyngitis acute tonsillitis, acute laryngitis, herpes stomatitis, superficial glossitis, acute and chronic gingivitis, ulcerative gingivitis, paro...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2006-003773-28 Sponsor Protocol Number: 06EU/FHp03 Start Date*: 2007-01-11
    Sponsor Name:IBSA
    Full Title: A multicentre, prospective, double-blind, in parallel groups randomised, versus placebo and versus reference product controlled, confirmatory clinical trial of the efficacy and tolerance of Flector...
    Medical condition: ankle sprains
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023229 Joint sprain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-005074-11 Sponsor Protocol Number: 14/GAR/002 Start Date*: 2015-04-29
    Sponsor Name:University Hospital South Manchester NHS Foundation Trust
    Full Title: The Role of GABAb receptor mechanisms in cough: Double-blind randomised controlled trial of Lesogaberan in Chronic cough patients with positive and negative symptom association probabilities
    Medical condition: Chronic cough
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004855 10066656 Chronic cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-001149-15 Sponsor Protocol Number: LevoDesa_05-2017 Start Date*: 2018-07-31
    Sponsor Name:NTC SRL
    Full Title: Aqueous humour concentrations after topical apPlication of combinEd levofloxacin dexamethasone eye dRops and of its single components: a randoMized, assEssor-blinded, parallel-group study in patien...
    Medical condition: Patients for which cataract surgery has been planned.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10007739 Cataract PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-004543-24 Sponsor Protocol Number: OVER2019 Start Date*: 2021-03-10
    Sponsor Name:Provincia Religiosa di S.Pietro Ordine Ospedaliero San Giovanni di Dio Fatebenefratelli
    Full Title: Intestinal preparation with new 1 L Peg + Asc solution or with gold standard 4 L Peg in split dose. Multicenter randomized controlled trial (OVER).
    Medical condition: Screening or surveillance or diagnostic colonoscopy.
    Disease: Version SOC Term Classification Code Term Level
    21.0 10022891 - Investigations 10010011 Colonoscopy normal PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003418-42 Sponsor Protocol Number: WOE_2013_TUE Start Date*: 2015-03-23
    Sponsor Name:Wörwag Pharma GmbH & Co. KG
    Full Title: Effect of Mg-Orotate administration on cardiocirculatory Performance, the muscular concentration of phosphocreatine and the adaptation of muscle cellular level: A double blind, randomized, placebo-...
    Medical condition: Evaluation of cardiocirculatory performance using clinical and relevant muscle laboratory parameters while taking Mg-Orotate and application of workouts
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-000814-21 Sponsor Protocol Number: BIA-PHL-P2-001 Start Date*: 2011-09-02
    Sponsor Name:BIAL INDUSTRIAL FARMACEUTICA, S.A.
    Full Title: A phase II, multicentre, randomized, double-blind study with subcutaneous immunotherapy at different doses, in parallel groups and placebo controlled in patients with rhinoconjunctivitis ± asthma s...
    Medical condition: allergic rhinoconjunctivitis induced by grass pollen
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10001728 Allergic rhinoconjunctivitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: PT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-016065-29 Sponsor Protocol Number: GWCA0962 Start Date*: 2010-03-10
    Sponsor Name:GW Pharma Ltd.
    Full Title: A double blind, randomized, placebo-controlled, parallel group study of Sativex oromucosal spray (Sativex®; Nabiximols) as adjunctive therapy in relieving uncontrolled persistent chronic pain in pa...
    Medical condition: Pain in patients with advanced cancer, who experience inadequate analgesia during optimized chronic opioid therapy.
    Disease: Version SOC Term Classification Code Term Level
    15.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10058019 Cancer pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) GB (Completed) DE (Completed) PL (Completed) BG (Completed) HU (Completed) RO (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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