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Clinical trials for Analgesics

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44364   clinical trials with a EudraCT protocol, of which   7388   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    411 result(s) found for: Analgesics. Displaying page 1 of 21.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2015-005247-14 Sponsor Protocol Number: CHUB-Equidol Start Date*: 2016-08-09
    Sponsor Name:Centre Hospitalier Universitaire Brugmann
    Full Title: Effect of levobupivacaine infiltration versus placebo on perineal postpartum pain in episiotomy of primiparous, after instrumental delivery: randomized double blind clinical trial.
    Medical condition: Episiotomy (inclusion of primiparous patients giving birth by instrumental delivery -Suzor forceps, vacuum extraction, Thierry spatulas with episiotomy).
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-000597-21 Sponsor Protocol Number: REMISYD Start Date*: 2008-05-27
    Sponsor Name:Kuopio University Hospital, Anesthesiology Clinic
    Full Title: Requirement of analgesics after two remifentanil dosing regimen in cardiac surgery.
    Medical condition: Post-operative requirement of analgesics in relation to remifentanil dose administered during cardiac surgery is to be investigated.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-010423-58 Sponsor Protocol Number: KF5503/42 Start Date*: 2009-08-28
    Sponsor Name:Grünenthal GmbH
    Full Title: An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with uncontrolled severe chr...
    Medical condition: Pain due to Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) DE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2013-004031-71 Sponsor Protocol Number: NL457401.094.13 Start Date*: 2015-01-14
    Sponsor Name:Spaarne Hospital
    Full Title: Local infiltration with anesthetics vs placebo in patients with elective total hip replacement (thr) in fast-track protocol
    Medical condition: primary coxarthrosis
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010425-39 Sponsor Protocol Number: KF5503/43 Start Date*: 2009-09-23
    Sponsor Name:Grünenthal GmbH
    Full Title: An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with severe chronic pain due...
    Medical condition: Pain due to Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) DE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-010428-25 Sponsor Protocol Number: KF5503/45 Start Date*: 2010-02-15
    Sponsor Name:Grünenthal GmbH
    Full Title: An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with severe chronic nocicept...
    Medical condition: Low back Pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024891 Low back pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) NL (Completed) DE (Completed) FR (Completed) BE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-010427-12 Sponsor Protocol Number: KF5503/44 Start Date*: 2009-10-14
    Sponsor Name:Grünenthal GmbH
    Full Title: An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with uncontrolled severe chr...
    Medical condition: Low back Pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024891 Low back pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FR (Completed) AT (Completed) DE (Completed) IT (Completed) PL (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2016-002924-99 Sponsor Protocol Number: NL.58160.091.16 Start Date*: 2016-10-27
    Sponsor Name:Radboudumc
    Full Title: The effectiveness of deep versus moderate neuromuscular blockade during laparoscopic donor nephrectomy in enhancing postoperative recovery.
    Medical condition: Live kidney donation is currently the most effect strategy to manage the shortage of donor kindeys for transplantation. Optimizing the safety and postoperative recovery after laparoscopic donornep...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2019-000203-33 Sponsor Protocol Number: 9119 Start Date*: 2019-10-16
    Sponsor Name:Klinisk Farmakologisk Afdeling
    Full Title: Paracetamol Discontinuation in the Elderly after long-term consumption (PARADISE)
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004867 10049475 Chronic pain LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-000107-36 Sponsor Protocol Number: VER-CLBP-001 Start Date*: 2021-03-24
    Sponsor Name:Vertanical GmbH
    Full Title: Proof of efficacy, maintenance of efficacy, long-term safety and investigation of the potential for dependence and abuse and the effect of abrupt drug withdrawal of VER-01 in a multicenter study in...
    Medical condition: For the treatment of patients with chronic non-specific low back pain when drug treatment is indicated and previous optimised treatments with non-opioid analgesics have not led to sufficient pain r...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000180-81 Sponsor Protocol Number: SLT4501 Start Date*: 2013-09-20
    Sponsor Name:Mundipharma Research GmbH & Co. KG
    Full Title: A single-arm, open-label, multicentre, non-randomised, study to assess the effect and tolerability of standardised laxative therapy (SLT) for the reversal of opioid-induced constipation (OIC) in s...
    Medical condition: Assess the effect and tolerability of standardised laxative therapy (SLT) for the reversal of opioid-induced constipation (OIC) in subjects suffering from malignant or non-malignant pain that requi...
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004856 10071128 Opioid induced constipation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2011-001315-31 Sponsor Protocol Number: GD032011 Start Date*: 2011-09-21
    Sponsor Name:University Hospitals Leuven
    Full Title: analgesia with continuous IV-infusion of lidocain during the perioperative period in patients undergoin laparoscopic sterilization.
    Medical condition: postoperative pain
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005488-25 Sponsor Protocol Number: 8833 Start Date*: 2017-02-02
    Sponsor Name:UH Montpellier
    Full Title: Evaluation of the effectiveness of intradiscal injection of corticosteroids in the Modic I discopathies
    Medical condition: chronic low back pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004313-82 Sponsor Protocol Number: 30-09-2014 Start Date*: 2015-02-03
    Sponsor Name:Anaesthesia and Operative Services, Kuopio University Hospital
    Full Title: Efficacy and safety of epidural oxycodone
    Medical condition: Acute postoperative pain after gynaecologic surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003619-22 Sponsor Protocol Number: A2370327 Start Date*: 2004-11-26
    Sponsor Name:GlaxoSmithKline Consumer Healthcare
    Full Title: A placebo-controlled study to investigate the efficacy of a combination analgesic treatment compared to its individual components in primary dysmenorrhoea.
    Medical condition: primary dysmenorrhoea
    Disease: Version SOC Term Classification Code Term Level
    7.1 10013935
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-005808-17 Sponsor Protocol Number: HEEL-2012-04 Start Date*: 2013-06-11
    Sponsor Name:Radboud University Medical Centre
    Full Title: The analgesic efficacy of perioperative Δ9-THC (Namisol®) in patients undergoing major abdominal surgery: a randomized, double blinded, placebo-controlled, parallel design
    Medical condition: Patients undergoing elective major abdominal surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10054799 Perioperative analgesia PT
    14.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-000534-36 Sponsor Protocol Number: PR 1903 Start Date*: 2004-09-13
    Sponsor Name:Laboratoires Expanscience
    Full Title: Efficacy and Safety of Piascledine 300 versus Chondroitin Sulfate in a 6 Months Treatment plus 2 Months Observation in Patients with Osteoarthritis of the Knee
    Medical condition: Osteoarthritis of the Knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) HU (Completed) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000613-35 Sponsor Protocol Number: BUP/005/C Start Date*: 2005-07-18
    Sponsor Name:Novosis AG
    Full Title: A double-blind, multi - centre, reference-controlled, randomised phase III study to compare the analgesic efficacy and tolerability of two buprenorphine transdermal systems using three different do...
    Medical condition: chronic, severe cancer pain inadequately controlled with other analgesics
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002177-11 Sponsor Protocol Number: 80-83600-98-20013 Start Date*: 2015-04-16
    Sponsor Name:ZonMW GGG
    Full Title: Step-down versus step-up analgesics in patients with (sub)acute sciatica in primary care
    Medical condition: Patients with (sub)acute sciatica in primary care.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002202-37 Sponsor Protocol Number: 2015-115 Start Date*: 2016-01-06
    Sponsor Name:radboudumc
    Full Title: Pilot study: Is concomitant administration of lidocaine during oxaliplatin infusion able to prevent pain as a result of oxaliplatin induced acute neuropathy?
    Medical condition: Acute oxaliplatin induced neuropathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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