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Clinical trials for Anesthesiology

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    141 result(s) found for: Anesthesiology. Displaying page 1 of 8.
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    EudraCT Number: 2015-002568-18 Sponsor Protocol Number: 5B Start Date*: 2015-07-15
    Sponsor Name:Stockholm County Council, Karolinska University Hospital Huddinge, Department of Anesthesiology and Intensive Care
    Full Title: Albumin mass balance and kinetics in liver transplantation. An open exploratory pilot study
    Medical condition: liver transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001587-35 Sponsor Protocol Number: Feline01 Start Date*: 2014-07-31
    Sponsor Name:Erasmus Medical Centre, Department of Anesthesiology
    Full Title: Dexmedetomidine in awake implantation of neuromodulative systems.
    Medical condition: Awake implantation of a neuromodulative system.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2015-002567-42 Sponsor Protocol Number: 5A Start Date*: 2015-07-15
    Sponsor Name:Stockholm County Council, Karolinska University Hospital Huddinge, Dept of Anesthesiology and Intensive Care
    Full Title: Predictors of albumin synthesis rate in severe liver failure. An open exploratory study in patients with chronic liver failure assessed for liver transplantation
    Medical condition: Severe chronic liver failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-005215-42 Sponsor Protocol Number: KloMid02 Start Date*: 2013-04-12
    Sponsor Name:Department of Anesthesiology and Intensive Care Medicine
    Full Title: Children's mood/anxiety, pain, nausea and behavioral changes after premedication with Clonidine versus Midazolam in ENT day surgery.
    Medical condition: Preanesthetic Medication at ear-nose-throat surgery
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000597-21 Sponsor Protocol Number: REMISYD Start Date*: 2008-05-27
    Sponsor Name:Kuopio University Hospital, Anesthesiology Clinic
    Full Title: Requirement of analgesics after two remifentanil dosing regimen in cardiac surgery.
    Medical condition: Post-operative requirement of analgesics in relation to remifentanil dose administered during cardiac surgery is to be investigated.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000903-10 Sponsor Protocol Number: 26022016 Start Date*: 2017-01-04
    Sponsor Name:Oulu University Hospital
    Full Title: Efficacy and blood concentrations of epidural hydromorphone in labour
    Medical condition: Labour pain
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-004698-34 Sponsor Protocol Number: ScDex_v1.0 Start Date*: 2016-01-26
    Sponsor Name:University Of Turku
    Full Title: Pharmacokinetics of subcutaneously given dexmedetomidine in healthy volunteers
    Medical condition: healthy volunteers are studied.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2012-002222-70 Sponsor Protocol Number: Lidobreast Start Date*: 2013-11-15
    Sponsor Name:University Medical Centre St Radboud
    Full Title: Pilot study: Targeting the inflammatory response after breast cancer surgery with lidocaïne and dexamethasone
    Medical condition: Breast cancer patients who undergo surgery for treatment.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2014-003730-10 Sponsor Protocol Number: 001-2014-KHTY Start Date*: 2014-12-01
    Sponsor Name:Department of Anesthesiology, Næstved Hospital
    Full Title: Effect of a lateral nerve of the thigh block on post-operative pain among patients with pain (VAS>40mm) during flexion of the hip the first or second postoperative day
    Medical condition: Pain after total hip replacement surgery
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10044088 Total hip replacement LLT
    17.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-001400-11 Sponsor Protocol Number: BBH-BDTAP-APP Start Date*: 2013-06-04
    Sponsor Name:Department of anesthesiology, Bispebjerg Hospital
    Full Title: Optimal postoperative pain management by ultrasoundguided abdominal wall nerve blockade for laparoscopic surgery for acute appendicitis - a randomised controlled trial.
    Medical condition: Postoperative pain following laparoscopic surgery due to acute appendicitis
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004862 10000677 Acute appendicitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-002586-34 Sponsor Protocol Number: STEROID_MC_1 Start Date*: 2020-11-12
    Sponsor Name:Department of Anesthesiology, Copenhagen University Hospital Hvidovre, Capital Region of Denmark
    Full Title: The effects of preoperative high-dose Dexamethasone on inflammatory response and recovery after emergency laparotomy, a randomized, double-blind, placebo-controlled clinical trial - AHA STEROID ...
    Medical condition: Patients undergoing emergency laparotomy due to either Intestinal obstruction or perforated abdominal viscus.
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10053361 Explorative laparotomy PT
    20.1 10018065 - General disorders and administration site conditions 10051379 Systemic inflammatory response syndrome PT
    22.0 10017947 - Gastrointestinal disorders 10021328 Ileus PT
    20.0 10017947 - Gastrointestinal disorders 10034406 Perforation bowel LLT
    20.0 10017947 - Gastrointestinal disorders 10034430 Perforation stomach LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000964-33 Sponsor Protocol Number: Feline02 Start Date*: 2015-09-17
    Sponsor Name:Erasmus Medical Center, Department of Anesthesiology
    Full Title: Dexmedetomidine versus propofol in awake implantation of a neuromodulative system.
    Medical condition: Awake implantation of a neuromodulative system.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2016-003144-36 Sponsor Protocol Number: NAC.TEP16 Start Date*: 2020-11-18
    Sponsor Name:Radboud University Medical Centre
    Full Title: Pilot study: postoperative pain reduction by pre emptive N-Acetylcysteine
    Medical condition: postoperative pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2021-006464-24 Sponsor Protocol Number: 20211125 Start Date*: 2022-12-14
    Sponsor Name:Rigshospitalet, Department of Anesthesiology, Juliane Marie Center
    Full Title: Intravenous MELAtonin for prevention of Postoperative Agitation and Emergence Delirium in children. The MELA-PAED trial: a randomized, double-blind, placebo-controlled clinical trial.
    Medical condition: Emergence delirium Postoperative agitation
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10050233 Delirium on emergence LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003267-31 Sponsor Protocol Number: oxy2006 Start Date*: 2006-07-19
    Sponsor Name:Department of anesthesiology
    Full Title: En sammenlignende undersøgelse af iv. oxycodon og iv. fentanyl i behandlingen af postoperative smerter efter laparoskopisk cholecystektomi.
    Medical condition: galdesten
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-005035-26 Sponsor Protocol Number: Methadone study Start Date*: 2005-04-05
    Sponsor Name:Anesthesiology Clinic,Akademiska Sjukhuset, Uppsala
    Full Title: Methadone in chronic non-cancer pain: rotation from other opioids and choice of dose
    Medical condition: Chronic non-cancer pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004867-19 Sponsor Protocol Number: v1330032015 Start Date*: 2015-02-24
    Sponsor Name:Clinic for General Anesthesiology, Intensive Care and Pain Management
    Full Title: Perioperative fluid management in patients receiving major abdominal surgery – Effects of normal saline versus an acetate buffered balanced infusion solution on the necessity of catecholamines for ...
    Medical condition: hemodynamic stability of patients undergoing major surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-001164-29 Sponsor Protocol Number: NMBDK2013 Start Date*: 2013-05-15
    Sponsor Name:Department of anesthesiology
    Full Title: Optimizing surgical conditions: Intraabdominal distance during gynecologic laparoscopic surgery with and without muscle relaxation (The measurement study)
    Medical condition: To investigate if deep neuromucular blockade improves intraabdominal volume compared to no neuromuscular blockade in patients scheduled for gynecologic laparoscopic surgery with pneumoperitoneum 12...
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10023692 Laparoscopically assisted hysterectomy LLT
    14.1 100000004865 10023691 Laparoscopic sterilization LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005344-17 Sponsor Protocol Number: CBDV_2014 Start Date*: 2015-08-21
    Sponsor Name:Department of Anesthesiology and Operative Intensive Care Medicine, Charité (CBF)
    Full Title: Oral cannabidivarin (CBDV) solution for treatment of HIV-associated neuropathic pain – a randomized, double-blind, placebo-controlled phase II study.
    Medical condition: Chronic painful HIV-associated neuropathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-002699-10 Sponsor Protocol Number: 80015401 Start Date*: 2021-01-06
    Sponsor Name:
    Full Title: High dose Ropivacaine versus moderate dose for quadratus lumborum block as postoperative analgesia after percutaneous nephrolithotomy – a blinded randomized non-inferiority study
    Medical condition: Postoperative pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10000081 Abdominal pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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