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Clinical trials for Antacids

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    29 result(s) found for: Antacids. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2009-014441-93 Sponsor Protocol Number: X-03030-3277 Start Date*: 2010-08-16
    Sponsor Name:MEDA Pharma GmbH & Co. KG
    Full Title: Clinical trial to assess the efficacy of the fixed combination product Tepilta® in the treatment of radiation-induced oesophagitis compared to its active ingredients oxetacaine and antacids, and t...
    Medical condition: Radiation-induced oesophagitis
    Disease: Version SOC Term Classification Code Term Level
    19.1 10022117 - Injury, poisoning and procedural complications 10048899 Radiation oesophagitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-002188-84 Sponsor Protocol Number: GA1203 Start Date*: 2012-07-27
    Sponsor Name:Reckitt Benckiser Healthcare (UK) LTD
    Full Title: A multi-centred, randomised, double-blind, two arm, parallel group, placebo-controlled, pilot study to assess the effect of Gaviscon Double Action Tablets in patients with reflux disease
    Medical condition: This pilot study of Gaviscon Double Action Tablets is to be conducted to demonstrate that Gaviscon Double Action Tablets are effective in managing the symptoms of heartburn, acid regurgitation and ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-004561-41 Sponsor Protocol Number: FGC-19-003 Start Date*: 2020-03-20
    Sponsor Name:The Functional Gut Clinic
    Full Title: The use of Antacids and Alginates during Pre-Investigation Proton Pump Inhibitor Washout: Impact on Compliance and Symptom Burden
    Medical condition: Gastro-oesophageal reflux disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004856 10066872 Acid reflux (esophageal) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2007-003000-35 Sponsor Protocol Number: Final Version 1.0 Hyposensitisation Start Date*: 2007-07-09
    Sponsor Name:Department of Occupational and Environmental Dermatology, Malmö University Hospital
    Full Title: A randomized controlled single blind multicenter study to investigate the induction of aluminium contact allergy in children/adults receiving hyposensitisation therapy due to allergic disease. Chi...
    Medical condition: The development of contact allergy to aluminium during hyposensitization therapy.
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019072-68 Sponsor Protocol Number: version 1 (07/10/2010) Start Date*: 2010-12-31
    Sponsor Name:Guy's & St Thomas' NHS Foundation Trust
    Full Title: A randomised, double blind, crossover study to determine the mechanism of action of Gaviscon Advance in Gastro-Oesophageal Reflux Disease (GORD)
    Medical condition: Gastro-oesophageal reflux disease (GORD)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-001284-20 Sponsor Protocol Number: BIOGIO Start Date*: 2017-07-05
    Sponsor Name:Erasmus MC Cancer Institute
    Full Title: The effects of the proton pump inhibitor esomeprazole on the bioavailability of afatinib (Giotrif®) in patients with non-small cell lung cancer (NSCLC) 'the BIO-GIO study'
    Medical condition: Non small cell lung cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001879-73 Sponsor Protocol Number: E3810-A001-202 Start Date*: 2016-06-27
    Sponsor Name:Eisai Medical Research Inc.
    Full Title: Safety and Efficacy of Rabeprazole in the Treatment of Gastroesophageal Reflux Disease in 12-16 Year Old Patients
    Medical condition: Gastroesophageal Reflux Disease
    Disease:
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2015-005784-17 Sponsor Protocol Number: REGORA Start Date*: 2016-05-19
    Sponsor Name:Erasmus MC cancer institute
    Full Title: The effects of the proton pump inhibitor esomeprazole on the bioavailability of regorafenib in patients with a metastatic colorectal cancer (mCRC) or gastrointestinal stromal tumour (GIST).
    Medical condition: GIST and mCRC patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002744-89 Sponsor Protocol Number: 20130620 Start Date*: 2014-01-27
    Sponsor Name:Erasmus MC
    Full Title: Bioavailability of oral ciprofloxacin tablets and suspension in pediatric cancer patients
    Medical condition: Microbial prophylaxis during cancer treatment
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-011543-40 Sponsor Protocol Number: R324 Start Date*: 2009-07-09
    Sponsor Name:Papworth Hospital
    Full Title: Assessment of platelet inhibitory response to clopidogrel when coadministered with a proton pump inhibitor
    Medical condition: To investigate in patients undergoing elective coronary stenting, the interaction between omeprazole, rabeprazole and ranitidine on clopodogrel inhibition of platelet activity in wild type (wt/wt) ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-000452-27 Sponsor Protocol Number: RABGRD1003 Start Date*: 2008-05-16
    Sponsor Name:Janssen-Cilag International N.V.
    Full Title: A Pharmacokinetic, Pharmacodynamic and Safety Study of Single and Multiple Doses of Rabeprazole in Pediatric Subjects with GERD 1 to 11 Months old, Inclusive
    Medical condition: Pediatric subjects with GERD
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018203 GERD LLT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-000451-97 Sponsor Protocol Number: RABGRD1002 Start Date*: 2008-04-25
    Sponsor Name:Janssen-Cilag International N.V.
    Full Title: A Pharmacokinetic and Safety Study of Single and Multiple Doses of Rabeprazole in Pediatric Subjects with GERD 1 to 11 Years old, inclusive
    Medical condition: Pediatric subjects with GERD (endoscopically proven) and have had endoscopic examination as part of their diagnostic evaluation; 1 to 11 Years Old, inclusive
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018203 GERD LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2018-002863-24 Sponsor Protocol Number: 65364 Start Date*: 2019-01-11
    Sponsor Name:Erasmus MC
    Full Title: Intralesional steroid injections to prevent refractory strictures in patinets with esophageal atresia - a randomized controlled trial
    Medical condition: Recurrent stenosis after correction of esophageal atresia
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: NL (Trial now transitioned) FI (Trial now transitioned) FR (Trial now transitioned) DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-005069-15 Sponsor Protocol Number: LIGHTHOUSEII Start Date*: 2021-06-23
    Sponsor Name:Stichting TRICALS Foundation
    Full Title: RANDOMISED DOUBLE-BLIND PLACEBO-CONTROLLED PHASE 3 TRIAL OF TRIUMEQ IN AMYOTROPHIC LATERAL SCLEROSIS
    Medical condition: Amyotrophic Lateral Sclerosis (ALS)
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029205 - Nervous system disorders 10002026 Amyotrophic lateral sclerosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned) IE (Trial now transitioned) ES (Ongoing) SI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-001863-38 Sponsor Protocol Number: iFAAM-PPIwalnut Start Date*: 2015-09-24
    Sponsor Name:Fundación para la investigación biomedica del hospital clinico san carlos de madrid
    Full Title: The impact of proton-pump inhibitors (antacids) on threshold dose distributions
    Medical condition: walnut allergic patients
    Disease: Version SOC Term Classification Code Term Level
    18.0 10021428 - Immune system disorders 10016946 Food allergy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-015885-75 Sponsor Protocol Number: RABGRD1005 Start Date*: 2010-07-02
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Pharmacokinetic, Pharmacodynamic and Short-term Safety Study of Single and Multiple Day Doses of Rabeprazole Sodium in Neonates and Pre-term Infants with a Corrected Age of Less than 44 Weeks wit...
    Medical condition: Gastroesophageal reflux disease (GERD) in neonates and pre-term infants, with a corrected age of less than 44 weeks at the time of the first dose.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10017947 - Gastrointestinal disorders 10018203 GERD LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-021630-63 Sponsor Protocol Number: GA1001 Start Date*: 2011-03-28
    Sponsor Name:Reckitt Benckiser
    Full Title: A randomised, double blind placebo controlled study in patients with reflux symptoms to assess suppression of gastro-oesophageal reflux by ‘Gaviscon Double Action Peppermint liquid’ using the BRAVO...
    Medical condition: Gastro-oesophageal reflux disease (GORD)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-001316-76 Sponsor Protocol Number: D9612L00109 Start Date*: 2006-07-20
    Sponsor Name:AstraZeneca GmbH
    Full Title: A randomized, open, parallel-group, multi-centre, phase IV study to evaluate the efficacy of three different patient management strategies with and without esomeprazole 20 mg during a 3 months main...
    Medical condition: Symptoms thought to be gastroesophageal reflux disease (GERD)-related
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2022-003287-25 Sponsor Protocol Number: 2018-002863-24,2022-003287-25 Start Date*: 2023-04-10
    Sponsor Name:Erasmus University Medical Center - Sophia Childrens Hospital
    Full Title: Intralesional steroid injections to prevent refractory strictures in patients with esophageal atresia - a randomized controlled trial
    Medical condition: Recurrent anastomotic strictures in the esophagus following surgical repair with primary anastomosis of esophageal atresia in neonates.
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-004465-27 Sponsor Protocol Number: COCA Start Date*: 2018-02-01
    Sponsor Name:Erasmus MC Cancer Institute
    Full Title: The effects of the proton pump inhibitor esomeprazole alone or in combination with Coca-Cola on the absorption of Capecitabine in patients with colorectal cancer or other solid tumours ' the COCA s...
    Medical condition: Colorectal carcinoma or other solid tumours
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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