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Clinical trials for Antidiuretic

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    14 result(s) found for: Antidiuretic. Displaying page 1 of 1.
    EudraCT Number: 2004-005239-25 Sponsor Protocol Number: CPR-SFY5904-EN-E01 Start Date*: 2005-07-06
    Sponsor Name:Sanofi-Synthelabo Research
    Full Title: An open-label, multicenter study evaluating the long-term safety and efficacy of SR121463B in patients with Syndrome of Inappropriate Antidiuretic Hormone Secretion.
    Medical condition: Syndrome of Inappropriate Antidiuretic Hormone (SIADH) with serum sodium between 115 and 132 mmol/L.
    Disease: Version SOC Term Classification Code Term Level
    7.1 10040626 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-005421-31 Sponsor Protocol Number: Start Date*: 2007-04-24
    Sponsor Name:RER Saint Denis
    Full Title: Effets hémodynamiques de l’administration de vasopressine au décours de l’Arrêt Cardio-Respiratoire chez des patients en état de choc réfractaire Hemodynamic effects of vasopressin administration i...
    Medical condition: Patients admitted in ICU after sucessfully resuscitated cardiac arrest and developping a refractory shock
    Disease: Version SOC Term Classification Code Term Level
    8.1 10047146 Vasopressin LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003800-38 Sponsor Protocol Number: SAFA-1-2014 Start Date*: 2014-02-24
    Sponsor Name:Department of Medical Research
    Full Title: The effects of tolvaptan on renal handling of water and sodium, vasoactive hormones and circulatory system, during basal conditions and during inhibition of the nitric oxide system in healthy subj...
    Medical condition: Hyponatremia SIADH (Syndrome of Inappropriate Antidiuretic Hormone secretion)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004861 10021038 Hyponatremia LLT
    14.1 100000004860 10040626 SIADH LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001169-33 Sponsor Protocol Number: SAFA-1-2012 Start Date*: 2012-07-02
    Sponsor Name:Department of Medical Research
    Full Title: Effects of tolvaptan on renal sodium and water handling and circulation during inhibition of the nitric oxide system in healthy subjects
    Medical condition: SIADH (Syndrome of inappropriate ADH production) Overhydration Hyponatrimia
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10021038 Hyponatremia LLT
    14.1 10014698 - Endocrine disorders 10040626 SIADH LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003336-12 Sponsor Protocol Number: FatherTrials2015 Start Date*: 2016-03-23
    Sponsor Name:Universiteit Leiden
    Full Title: Father Trials: Hormonal Experiments on Prenatal and Postnatal Parenting
    Medical condition: There are no medical conditions or diseases under investigation
    Disease: Version SOC Term Classification Code Term Level
    18.1 10022891 - Investigations 10047146 Vasopressin LLT
    18.1 10022891 - Investigations 10033329 Oxytocin PT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001973-15 Sponsor Protocol Number: SAFA-2-2014 Start Date*: 2014-11-18
    Sponsor Name:University Clinic in Nephrology and Hypertension, Department of Medical Research
    Full Title: Renal Handling of Water and Sodium in Autosomal Dominant Polycystic Kidney Disease. The effects of tolvaptan on renal handling of water and sodium , vasoactive hormones and central hemodynamics dur...
    Medical condition: Hyponatreamia SIADH ( Syndrome of Inappropriate Antidiuretic Hormone Secretion) Overhydration Autosomal dominant polycystic kidney disease
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004861 10021038 Hyponatremia LLT
    17.0 100000004860 10040626 SIADH LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004071-39 Sponsor Protocol Number: TOLV2012 Start Date*: 2012-10-16
    Sponsor Name:FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO DI MILANO
    Full Title: Study on the effectiveness and safety of the treatment of mild-moderate symptomatic hyponatremia due to syndrome of inappropriate secretion of antidiuretic hormone (SIADH) with Tolvaptan vs fluid ...
    Medical condition: Mild-moderate symptomatic hyponatremia due to syndrome of inappropriate secretion of antidiuretic hormone (SIADH)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10014698 - Endocrine disorders 10014698 Endocrine disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002349-11 Sponsor Protocol Number: EFC4489 Start Date*: 2004-11-03
    Sponsor Name:Sanofi-Synthelabo Research
    Full Title: A randomisation, double-blind, placebo-controlled, parallel-group, multicenter study evaluating the efficacy and safety of SR121463B in patients with syndrome of inappropriate antidiuretic hormone ...
    Medical condition: Síndrome de secreción inadecuada de hormona antidiurética
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-003774-17 Sponsor Protocol Number: 483-001 Start Date*: 2008-08-01
    Sponsor Name:Vantia Ltd
    Full Title: A double-blind, placebo-controlled dose response study to investigate pharmacodynamics and pharmacokinetics of single and repeated oral doses of VA106483 in elderly male subjects
    Medical condition: Nocturia.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029446 Nocturia LLT
    Population Age: Elderly Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001754-26 Sponsor Protocol Number: CK-LX3405 Start Date*: 2008-10-08
    Sponsor Name:Cardiokine Biopharma, LLC
    Full Title: Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Oral Lixivaptan Capsules in Subjects with Euvolemic Hyponatremia
    Medical condition: Subjects with euvolemic hyponatremia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021038 Hyponatremia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-003966-25 Sponsor Protocol Number: DEPOPA Start Date*: 2008-12-23
    Sponsor Name:Universität Mainz, Klinik und Poliklinik für Neurologie
    Full Title: Double-blind, placebo controlled, randomised, monocenter cross-over studie to evaluate the effect of Desmopressin on the nocturnal polyuria in patients with idiopathic Parkinson Syndrome compared t...
    Medical condition: Effect of Desmopressin on the nocturnal polyuria in patients with idiopathic Parkinson Syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064016 Nocturnal polyuria LLT
    9.1 10061536 Parkinson's disease LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-007941-10 Sponsor Protocol Number: EFC10102 Start Date*: 2008-06-11
    Sponsor Name:sanofi-aventis recherche et développement
    Full Title: A Double-Blind, Randomized, Placebo-Controlled Multicenter Study Evaluating the Efficacy and Safety of two doses of Satavaptan (SR121463B) Versus Placebo in Patients with Dilutional Hyponatremia du...
    Medical condition: Dilutional hyponatraemia. MedRA term "HYPONATRAEMIA"
    Disease: Version SOC Term Classification Code Term Level
    10.1 10021036 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) FR (Completed) HU (Prematurely Ended) BE (Completed)
    Trial results: View results
    EudraCT Number: 2004-003985-14 Sponsor Protocol Number: CPR-EFC5816-EN-E01 Start Date*: 2005-05-23
    Sponsor Name:Sanofi-Synthelabo Research
    Full Title: A Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial Evaluating the Effect of Two Doses of a Vasopressin V2 Receptor Antagonist (SR121463B) on Serum Sodium in Patients with Dilutional ...
    Medical condition: Dilutional hyponatremia excluding chronic syndrome of inappropriate antidiuretic hormone secretion (SIADH) or cirrhosis
    Disease: Version SOC Term Classification Code Term Level
    7.1 10021038 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) BE (Completed) SE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2008-003191-21 Sponsor Protocol Number: CK-LX3430 Start Date*: 2009-08-20
    Sponsor Name:Cardiokine Biopharma, LLC
    Full Title: Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of Oral Lixivaptan Capsules in Subjects with Euvolemic Hyponatremia
    Medical condition: Euvolemic hyponatremia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021038 Hyponatremia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) BE (Completed) IT (Completed) DE (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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