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Clinical trials for Appendicitis

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    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    33 result(s) found for: Appendicitis. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2015-003634-26 Sponsor Protocol Number: T151/2015 Start Date*: 2016-12-27
    Sponsor Name:Turku University Hospital
    Full Title: Antibiotic therapy vs. placebo in the treatment of acute uncomplicated appendicitis: a prospective randomized double-blind placebo-controlled trial
    Medical condition: Acute uncomplicated appendicitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10000677 Acute appendicitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-003633-10 Sponsor Protocol Number: T150/2015 Start Date*: 2016-03-03
    Sponsor Name:Turku University Hospital
    Full Title: Optimizing the antibiotic treatment of uncomplicated acute appendicitis: a prospective randomized multicenter study
    Medical condition: Uncomplicated acute appendicitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10000677 Acute appendicitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-003655-29 Sponsor Protocol Number: T216/2016 Start Date*: 2017-02-23
    Sponsor Name:Turku University Hospital
    Full Title: Acute appendicitis and microbiota- etiology and effects of the antimicrobial treatment
    Medical condition: Acute appendicitis
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004862 10000677 Acute appendicitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-001400-11 Sponsor Protocol Number: BBH-BDTAP-APP Start Date*: 2013-06-04
    Sponsor Name:Department of anesthesiology, Bispebjerg Hospital
    Full Title: Optimal postoperative pain management by ultrasoundguided abdominal wall nerve blockade for laparoscopic surgery for acute appendicitis - a randomised controlled trial.
    Medical condition: Postoperative pain following laparoscopic surgery due to acute appendicitis
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004862 10000677 Acute appendicitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-002977-44 Sponsor Protocol Number: ASAA-Study Start Date*: 2011-06-28
    Sponsor Name:AZIENDA OSPEDALIERA "OSPEDALI RIUNITI DI BERGAMO" (A.O. DI RILIEVO NAZIONALE)
    Full Title: Antibiotics vs Surgery in Acute Appendicitis: an intention to treat prospective randomised controlled study, The ASAA-Study
    Medical condition: All the patients between 18 and 65 years old admitted to the hospital with a first episode of suspected acute appendicitis diagnosed by Andersson's score
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10000677 Acute appendicitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017626-39 Sponsor Protocol Number: APPAC Start Date*: 2010-02-08
    Sponsor Name:The Hospital District of Southwest Finland
    Full Title: Akuutin appendisiitin hoito: leikkaus- vs. antibioottihoito
    Medical condition: Acute uncomplicated appendicitis
    Disease: Version SOC Term Classification Code Term Level
    12.1 10003011 Appendicitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004800-46 Sponsor Protocol Number: 2015-810 Start Date*: 2016-01-21
    Sponsor Name:Kirurgisk Afdeling, Nordsjællands Hospital
    Full Title: Preoperative methylprednisolone to patients suspected of appendicitis undergoing laparoscopy.
    Medical condition: Patientns undergoing laparoscopy for suspected appendicitis
    Disease: Version SOC Term Classification Code Term Level
    18.1 10021881 - Infections and infestations 10003011 Appendicitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-005040-18 Sponsor Protocol Number: 2014-707 Start Date*: 2015-03-02
    Sponsor Name:Kirurgisk afdeling, Nordsjællands Hospital
    Full Title: Preoperativ dexamethasone for patients undergoing laparoscopy for suspected appendicitis.
    Medical condition: Patients undergoing laparoscopy for suspected appendicitis
    Disease: Version SOC Term Classification Code Term Level
    17.1 10021881 - Infections and infestations 10003011 Appendicitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-003052-70 Sponsor Protocol Number: APAC2016 Start Date*: 2016-11-10
    Sponsor Name:Academic Medical Center of Amsterdam
    Full Title: Initial non-operative treatment strategy versus appendectomy treatment strategy for simple appendicitis in children aged 7-17 years old. APAC study
    Medical condition: Acute uncomplicated (simple) appendicitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10003011 Appendicitis PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005772-16 Sponsor Protocol Number: HEH-SF-01 Start Date*: 2016-06-22
    Sponsor Name:Department of Surgery, Herlev Hospital
    Full Title: The safety and pharmacokinetics of intraperitoneal administration of granulocyte-macrophage colony-stimulating factor, fosfomycin, and metronidazole in patients undergoing appendectomy for uncompli...
    Medical condition: We intend to investigate the safety of treating secondary infectious peritonitis due to uncomplicated appendicitis with intraperitoneally administered fosfomycin, metronidazole and GM-CSF.
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004862 10000677 Acute appendicitis LLT
    19.0 100000004848 10053349 Pharmacokinetic study LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-002348-26 Sponsor Protocol Number: HUS-PERFECT Start Date*: 2020-02-18
    Sponsor Name:Helsinki University Hospital
    Full Title: Role of delay and antibiotics on PERForation rate while waiting appendECTomy – Randomized non-inferiority trial (PERFECT)
    Medical condition: Acute appendicitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001578-71 Sponsor Protocol Number: App2018 Start Date*: 2018-07-30
    Sponsor Name:Göteborgs Universitet
    Full Title: Optimized treatment for uncomplicated acute appendicitis - active observation with or without antibiotic treatment. A phase IV consecutive clinical treatment trial.
    Medical condition: Acute appendicitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2021-001400-16 Sponsor Protocol Number: 6-1/05/1 Start Date*: 2021-07-02
    Sponsor Name:Riga Stradins university
    Full Title: Investigation of pain syndrome and clinical-biochemical parameters in 7 to 18 years old children with acute uncomplicated appendicitis who received non-surgical treatment.
    Medical condition: Pain syndrome in 7 to 18 years old children with acute uncomplicated appendicitis, who received non-surgical treatment.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: LV (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-004495-12 Sponsor Protocol Number: KCA2011/APAC Start Date*: 2017-05-18
    Sponsor Name:VU University Medical center
    Full Title: Antibiotic treatment alone for children with acute appendicitis; a prospective cohort study part of the Antibiotic versus Primary Appendectomy for Children with acute appendicitis; the APAC trial.
    Medical condition: Radiologically confirmed simple appendicitis, defined as: a. Clinical findings: Unwell, but not generally ill, Localized tenderness in the right iliac fossa region, Normal/hyperactive bowel sound...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2013-000498-56 Sponsor Protocol Number: NL42396.042.12 Start Date*: 2013-09-03
    Sponsor Name:UMCG
    Full Title: 1. Does supported faecal production accelerates the final diagnosis in children with acute abdominal pain? 2. Primary CMV and HHV-6 infection associated with the pathogenesis of acute appendicitis...
    Medical condition: 1. Acute abdominal pain 2. Appendicitis
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-001729-38 Sponsor Protocol Number: 6-1/13/2020/31 Start Date*: 2021-07-02
    Sponsor Name:Arnis Eņģelis
    Full Title: Clinical and economical efficiency and safety and inflammation parameter correlations study of concervative treatment of non-complicated acute appendicitis in 7 to 18 years old children.
    Medical condition: Acute non-complicated appendicitis in patients aged 7 to 18
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: LV (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-003428-21 Sponsor Protocol Number: ABPOSTOPAPP Start Date*: 2017-03-14
    Sponsor Name:Erasmus Medical Centre
    Full Title: Non-inferiority multicentre randomized controlled trial comparing short versus standard course postoperative antibiotic treatment for complex acute appendicitis
    Medical condition: Complex appendicitis.
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004753-16 Sponsor Protocol Number: HEH-SF-02 Start Date*: 2018-02-01
    Sponsor Name:Department of Surgery, Herlev Hospital
    Full Title: Intraperitoneal administration of fosfomycin, metronidazole and molgramostim versus intravenous conventional antibiotics for perforated appendicitis – a pivotal quasi-randomized controlled trial
    Medical condition: We wish to investigate if intraoperative intraperitoneal administration of fosfomycin, metronidazole and rhGM-CSF followed by oral antibiotic for three days is as effective as the current intraveno...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10000680 Acute appendicitis without mention of peritonitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2008-001525-34 Sponsor Protocol Number: RD - 5103 – 001 - 08 Start Date*: 2008-05-13
    Sponsor Name:Derby Hospitals NHS Foundation Trust
    Full Title: THE ANALGESIC EFFICACY OF ULTRASOUND GUIDED TRANSVERSUS ABDOMINIS PLANE (TAP) BLOCK IN PATIENTS UNDERGOING OPEN APPENDICECTOMY: A PILOT STUDY
    Medical condition: Adult patients suffering fro appendicitis who are scheduled for open surgery(Open Appendicectomy)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-002121-80 Sponsor Protocol Number: 47/2007/O/Sper Start Date*: 2007-09-25
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: A prospective, double-blind, multi center, randomized clinical study to compare the efficacy and safety of Ertapenem 3 days versus Ampicillin- Sulbactam 3 days in the treatment of localized communi...
    Medical condition: localized community acquired intra-abdominal infection (IAI)
    Disease: Version SOC Term Classification Code Term Level
    6.1 10017967 HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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