Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Ascorbic acid (vitamin C)

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44343   clinical trials with a EudraCT protocol, of which   7372   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    40 result(s) found for: Ascorbic acid (vitamin C). Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2014-005612-41 Sponsor Protocol Number: 15-15 Start Date*: 2015-11-30
    Sponsor Name:Meander Medical Centre
    Full Title: Vitamin c to Improve Tissue healing by Administration of Multiple INtravenous dosages
    Medical condition: Patients with planned revascularisation surgery on the lower extremities.
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004848 10003451 Ascorbic acid LLT
    18.1 10042613 - Surgical and medical procedures 10063919 Bypass surgery LLT
    18.1 10042613 - Surgical and medical procedures 10036892 Promotion of wound healing PT
    18.1 10042613 - Surgical and medical procedures 10061407 Vascular bypass graft LLT
    18.1 10042613 - Surgical and medical procedures 10053375 Peripheral revascularization LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-003703-21 Sponsor Protocol Number: 5802003 Start Date*: 2005-01-28
    Sponsor Name:Semmelweis University
    Full Title: The role of hyperhomocysteinemia in the genesis of atherothrombotic vascular disease
    Medical condition: Established cardiovascular disease with elevated levels of homocystein
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002975-17 Sponsor Protocol Number: EMS/2004/017-04/33 Start Date*: 2005-01-31
    Sponsor Name:Epsom & St Helier University Hospitals NHS Trust
    Full Title: A pilot study to examine the effect of vitamin C on bone turnover and antioxidant levels in postmenopausal women with low bone density
    Medical condition: low bone density / osteoporosis postmenopausal women
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-004135-77 Sponsor Protocol Number: 68010 Start Date*: 2019-04-03
    Sponsor Name:MUMC
    Full Title: Randomized controlled trial on the effect of vitamin C supplementation in autologous stem cell transplantations
    Medical condition: adults (minimally 18 years old) that are planed to receive an autologous stem cell transplantation for a hematological malignancy (myeloma or lymphoma)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-003635-46 Sponsor Protocol Number: 05/MRE10/72 Start Date*: 2006-05-16
    Sponsor Name:NHS Lothian University, Research & Development
    Full Title: Do Anti-Oxidants Modulate the Outcome of Fractures? The Effect of Vitamin C on Functional Outcome Following Fracture of Distal Radius: A Prospective randomised controlled trial.
    Medical condition: Adult patients with fractures of the distal radius.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-003790-41 Sponsor Protocol Number: JAN12006-01 Start Date*: 2015-05-11
    Sponsor Name:Spherium Biomed
    Full Title: Randomised, double-blinded, placebo and active comparator controlled exploratory clinical trial to assess the efficacy and safety of a triple combination of Ibuprofen, magnesium and ascorbic acid ...
    Medical condition: Temporomandibular joint dysfunction syndrome.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004318-25 Sponsor Protocol Number: NL63681.029.18 Start Date*: 2019-04-16
    Sponsor Name:VU University Medical Center
    Full Title: Early high-dose vitamin C in post-cardiac arrest syndrome.
    Medical condition: Patients admitted to the Intensive Care after out-of-hospital cardiac arrest with return of spontaneous circulation, ventricular fibrillation or ventricular tachycardia as first registered cardiac ...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10078202 Post cardiac arrest syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000196-32 Sponsor Protocol Number: METABOLICRESUS Start Date*: 2018-11-06
    Sponsor Name:HU DE GIRONA DR JOSEP TRUETA
    Full Title: PILOT STUDY ON THE USE OF HYDROCORTISONE, VITAMIN C AND THYAMINE IN PATIENT WITH SEPSIS AND SEPTIC SHOCK.
    Medical condition: sepsis and septic shock
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10040054 Sepsis, bacteraemia, viraemia and fungaemia NEC HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-002696-32 Sponsor Protocol Number: MASTVITC-001 Start Date*: 2005-09-20
    Sponsor Name:FAZ - Floridsdorf Allergy Center
    Full Title: DIE WIRKUNG VON INTRAVENÖSEM VITAMIN C AUF HISTAMINSPIEGEL UND DIAMINOXIDASEAKTIVITÄT IM BLUT BEI MASTOZYTOSEPATIENTEN
    Medical condition: Die Mastozytose ist durch eine Akkumulation von Mastzellen gekennzeichnet.Alle Mastozytosen können bei Mastzelldegranulation, bei der HISTAMIN ausgeschüttet wird, mit Symptomen einhergehen. In der ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-001239-11 Sponsor Protocol Number: V4_010616 Start Date*: 2016-10-17
    Sponsor Name:Orthopädisches Spital Speising
    Full Title: PONV – Histamin - Vitamin C A prospecitve, Placebo-controlled dobbleblind study
    Medical condition: PONV
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005460-42 Sponsor Protocol Number: SXF2-8 Start Date*: 2016-07-07
    Sponsor Name:Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
    Full Title: Phase III clinical trial, double-blind, cross-way, to evaluate the safety and efficacy ascorbic acid (vitamin C) and tocopherol (vitamin E) combination versus placebo for the treatment of cognitive...
    Medical condition: Fragile x syndrome
    Disease: Version SOC Term Classification Code Term Level
    19.0 10010331 - Congenital, familial and genetic disorders 10017324 Fragile X syndrome PT
    Population Age: Children, Under 18 Gender: Male
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000145-24 Sponsor Protocol Number: PI2015_843_0001 Start Date*: 2015-09-21
    Sponsor Name:CHU Amiens - Picardie
    Full Title: Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery (CRPS-VITC)
    Medical condition: Algoneurodystrophy CRPS type 1
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004852 10001665 Algoneurodystrophy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-002520-16 Sponsor Protocol Number: 626 Start Date*: 2007-07-06
    Sponsor Name:Universitätsklinik für klinische Pharmakologie, Medizinische Universität Wien
    Full Title: The effects of post-conditioning and administration of Vitamin C on intramuscular high energy phosphate levels
    Medical condition: ischemia reperfusion injury
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023034 Ischemia peripheral LLT
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-008692-33 Sponsor Protocol Number: 2008-242 Start Date*: 2009-04-21
    Sponsor Name:Department of Urology, Herlev Hospital
    Full Title: Evaluation of cytotoxicity and genetic changes of high dose vitamin C infusions in castration resistant metastatic human prostate cancer.
    Medical condition: The effect of high dose intravenous weekly vitamin c infusion in castration resistant human prostate cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10036909 Prostate cancer metastatic PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10062904 Hormone-refractory prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002273-41 Sponsor Protocol Number: OPHT-110106 Start Date*: 2006-06-12
    Sponsor Name:Medical University of Vienna; Clinical Pharmacology
    Full Title: Effect of antioxidants on ocular blood flow, endothelial function, and cytokine levels in LPS induced inflammatory model in humans.
    Medical condition: only healthy volunteers are involved
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-003139-39 Sponsor Protocol Number: JAN12006-09 Start Date*: 2017-05-16
    Sponsor Name:Spherium Biomed
    Full Title: Double-blind, randomized, placebo-controlled, Single-center, Exploratory Clinical Trial to Investigate Safety and Efficacy of COMBOPROFEN for treatment of muscular pain associated with DOMS
    Medical condition: Delayed onset muscular soreness
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-002211-24 Sponsor Protocol Number: VITC-001 Start Date*: 2006-10-27
    Sponsor Name:FAZ - Floridsdorf Allergy Center
    Full Title: Wirksamkeit von oralem Vitamin C bei der Seekrankheit
    Medical condition: Die Seekrankheit (motion sickness) stellt ein weiterhin aktuelles Problem in der professionellen wie nicht-professionellen Seefahrt sowie auch beim Transport mit anderen Fortbewegungsmitteln (Auto,...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001862-12 Sponsor Protocol Number: s63213 Start Date*: 2021-03-23
    Sponsor Name:University Hospitals Leuven, Clinical Trial Centre
    Full Title: Early administration of Vitamin C in patients with sepsis or septic shock in emergency departments: a multicentre, double blinded, randomized controlled trial: the C-EASIE trial.
    Medical condition: We will investigate the potential benefit of early administration of high doses of Vitamin C in addition to standard care in patients with sepsis or septic shock.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    23.1 10021881 - Infections and infestations 10040070 Septic shock PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2019-003350-80 Sponsor Protocol Number: APHP190843 Start Date*: 2020-01-15
    Sponsor Name:Université de Sherbrooke
    Full Title: Lessening Organ Dysfunction with VITamin C (LOVIT)
    Medical condition: Sepsis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004276-35 Sponsor Protocol Number: PI-0290-2012 Start Date*: 2014-10-10
    Sponsor Name:Hospital Regional Universitario. IBIMA
    Full Title: Phase II, Double-blind, randomized, 1-way cross-over, to investigate the effectiveness of the combination of ascorbic acid (vitamin C) and tocopherol (vitamin E) versus placebo for the treatment of...
    Medical condition: The trial aims to treat depression. The incidence of major depression in the elderly accounts for between 3.6 and 4.8% and increases to 8 to 37.4% when depressive disorders in general is studied. B...
    Disease: Version SOC Term Classification Code Term Level
    17.0 10037175 - Psychiatric disorders 10012378 Depression PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Mon Jun 16 11:48:50 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA