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Clinical trials for Bacteria

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    455 result(s) found for: Bacteria. Displaying page 1 of 23.
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    EudraCT Number: 2005-004890-10 Sponsor Protocol Number: KI DS 200509 Start Date*: 2006-02-17
    Sponsor Name:Kvinnokliniken
    Full Title: Vaginal colonization of the LN bacteria (patented human lactic acid producing bacteria) when conventional treatment of bacterial vaginosis and Candida vaginitis is followed by treatment with Vagipi...
    Medical condition: Diagnosed Bacterial Vaginosis (BV) or Candida Vaginitis(CV) ICD: N76.8 (BV); N77.1*B37.3+(CV)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-003048-11 Sponsor Protocol Number: GIPIT002 Start Date*: 2014-10-24
    Sponsor Name:GIPIT
    Full Title: FEcal transplant, a Dazzling debut to Eradicate colonization with eXtreme drug resistant bacteria?
    Medical condition: Patient harboring Extreme Drug Resistant (XDR) bacteria. Our trial try to eradicate this digestive tract colonization by performing a fecal transplantation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016566-82 Sponsor Protocol Number: 05/SP/120 Start Date*: 2009-12-29
    Sponsor Name:Belfast Health and Social Care Trust [...]
    1. Belfast Health and Social Care Trust
    2. Queen's University Belfast
    Full Title: Skin bacteria as a source of surgical infections: molecular epidemiology and prevention of wound contaimination
    Medical condition: No medical condition under investigation, investigation of surgical wound contamination in spinal patients.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-005833-38 Sponsor Protocol Number: LCR35_ESBL-01 Start Date*: 2012-07-03
    Sponsor Name:Medical University of Vienna
    Full Title: Removal of intestinal colonization with multi resistant bacteria by ingestion of Lactobacillus casei rhamnosus LCR 35
    Medical condition: Intestinal colonisation with multiresistant bacteria
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10069719 Bacterial colonisation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-023529-39 Sponsor Protocol Number: RHM CHI 0548 Start Date*: 2011-02-18
    Sponsor Name:Southampton University Hopsitals NHS Trust
    Full Title: Reducing antibiotic tolerance using low dose nitric oxide in cystic fibrosis – a phase 2 pilot study
    Medical condition: Cystic Fibrosis
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-010713-69 Sponsor Protocol Number: LINPT01 Start Date*: 2009-05-13
    Sponsor Name:Lek Pharmaceuticals d.d.
    Full Title: Randomized, placebo controlled, double-blind, parallel group, multicentric Phase IV study on the clinical efficacy of lactic acid bacteria in form of hard capsules (capsule contains not less than 2...
    Medical condition: Antibiotic associated diarrhea
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: View results
    EudraCT Number: 2010-023889-52 Sponsor Protocol Number: AntiResDev-SWE Start Date*: 2011-01-18
    Sponsor Name:Karolinska Universitetssjukhuset
    Full Title: Effects of Clindamycin and Ciprofloxacin administration on the emergence, prevalence and persistence of antibiotic-resistant bacteria in humans
    Medical condition: To assess the effect of ciprofloxacin and clindamycin administration on the proportions and types of cultivable antibiotic-resistant bacteria that emerge in the oropharynx, on the skin and in the...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-000244-10 Sponsor Protocol Number: EGBAB Start Date*: 2019-12-13
    Sponsor Name:Region Uppsala
    Full Title: Influence of antibiotic treatment on the normal flora and the presence of resistance genes in known carriers of ESBL and VRE
    Medical condition: Carriage of genes coding for vancomycin resistant enterococci (VRE) and extended spectrum betalactamase producing enterobacteriales (EPE) phenotypes.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-004634-26 Sponsor Protocol Number: 4896 Start Date*: 2015-05-20
    Sponsor Name:Royal Liverpool University Hospital [...]
    1. Royal Liverpool University Hospital
    2. Liverpool School of Tropical Medicine
    Full Title: The Effect of Live Attenuated Influenza Vaccine (LAIV) on Experimental Human Pneumococcal Colonisation (EHPC) Study
    Medical condition: Pneumococcal colonisation post inoculation
    Disease: Version SOC Term Classification Code Term Level
    18.1 10042613 - Surgical and medical procedures 10059429 Influenza immunisation PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-001774-24 Sponsor Protocol Number: 3574 Start Date*: 2006-09-13
    Sponsor Name:Newcastle u Tyne Hospitals NHS Trust
    Full Title: INTESTINAL MICRO-ORGANISMS IN THE PATHOGENESIS OF NASH AND THE ROLE OF MODULATION OF ENTERIC BACTERIA IN TREATMENT.
    Medical condition: Non alcoholic fatty liver disease (NAFLD)/steatohepatitis (NASH)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2011-002343-99 Sponsor Protocol Number: 1.0 Start Date*: 2012-01-03
    Sponsor Name:Heart of England NHS Foundation Trust
    Full Title: An Open-label Study into the Efficacy and Dosing of Probiotic Escherichia coli Nissle 1917 for Prevention of Gram-negative Gastric Colonisation in Ventilated Intensive Care Patients.
    Medical condition: Gastric colonisation by pathogenic gram negative bacteria in ventilated adult ICU patients and it's prevention by the probiotic E.coli Nissle 1917
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005738-12 Sponsor Protocol Number: LIPSTIC.V.01 Start Date*: 2013-03-27
    Sponsor Name:Alder Hey Children's NHS Foundation Trust
    Full Title: Liverpool Pharmacokinetic/pharmacodynamics study of teicoplanin in children (LIPSTIC).
    Medical condition: Gram-positive bacterial infection: late-onset neonatal sepsis, central line-associated blood stream infection, ventilator-associated pneumonia.
    Disease:
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021879-85 Sponsor Protocol Number: 10050 Start Date*: 2010-09-08
    Sponsor Name:University of Nottingham
    Full Title: Mode of action of Moviprep:impact on distribution of intestinal fluid and colonic microbiota
    Medical condition: for bowel cleansing prior to any clinical procedure requiring a clean bowel, e.g, bowel endoscopy, lower gastrointestinal tract radiology or digestive tract surgery.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-002876-32 Sponsor Protocol Number: AAD-CDD-001 Start Date*: 2008-10-06
    Sponsor Name:University of Wales Swansea
    Full Title: A multicentre, randomised, placebo controlled trial of lactic acid bacteria in the prevention of antibiotic-associated diarrhoea (AAD) and Clostridium difficile diarrhoea (CDD) in patients aged 65 ...
    Medical condition: AAD is diarrhoea occurring in association with antibiotic treatment without an alternative cause. It occurs typically 2-8 weeks after exposure to antibiotics. The frequency of AAD varies markedly b...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064065 Prophylaxis against diarrhoea PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-009948-23 Sponsor Protocol Number: H 552 000-0902 Start Date*: Information not available in EudraCT
    Sponsor Name:Almirall Hermal GmbH
    Full Title: A phase IIa single-center, randomized, controlled, observer-blind study to investigate the antimicrobial efficacy of topical formulations containing octenidine and prednicarbate in an "expanded flo...
    Medical condition: Healthy volunteer trial to investigate whether topical formulations containing octenidine and octenidine plus prednicarbate exert an in vivo antibacterial action on skin surface bacteria multiplied...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-003362-26 Sponsor Protocol Number: H552000-0809 Start Date*: Information not available in EudraCT
    Sponsor Name:Almirall Hermal GmbH
    Full Title: A phase IIa single-center, randomized, controlled, observer-blind study to investigate the antimicrobial efficacy of topical formulations containing octenidine and prednicarbate in an"expanded flor...
    Medical condition: Healthy volunteer trial to investigate whether topical formulations containing Octenidine and Octenidine plus Prednicarbate exert an in vivo antibacterial action on skin surface bacteria multiplied...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017823-24 Sponsor Protocol Number: 1703 Start Date*: 2010-03-19
    Sponsor Name:Tartu University Hospital
    Full Title: Meropenem pharmacokinetics in very low birth weight neonates
    Medical condition: proven or suspected sepsis, lower respiratory tract infection, complicated intraabdominal infection
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: EE (Completed)
    Trial results: View results
    EudraCT Number: 2014-005308-12 Sponsor Protocol Number: 1111 Start Date*: 2018-09-07
    Sponsor Name:Region Sjælland, Slagelse Hospital
    Full Title: Treatment of MRSA throat carriage with mupirocin irrigation
    Medical condition: Patientents being MRSA positive for a minimum of 6 months and concluded at least one konventional topical treatments unsuccessfully
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10061554 Staphylococcal pharyngitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-003321-29 Sponsor Protocol Number: 17-169 Start Date*: Information not available in EudraCT
    Sponsor Name:RWTH Aachen University represented by the Rector himself, represented by the Dean of the Medical Faculty
    Full Title: Clinical relevance of the antimicrobial resistance testing in the treatment of chronic wounds with antiseptics
    Medical condition: Decubitus, acute or chronic wounds (open wounds existing ≥ 14 days)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-002751-38 Sponsor Protocol Number: PREPREP Start Date*: 2021-02-01
    Sponsor Name:Region Östergötland
    Full Title: Long-term effect of chlorhexidine gluconate 4% and Chlorhexidine alcohol 5 mg /ml on growth and recolonisation of bacteria on the skin
    Medical condition: Cutaneous antibacterial efficacy in healthy volunteers.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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