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Clinical trials for Cancer surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    2,880 result(s) found for: Cancer surgery. Displaying page 1 of 144.
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    EudraCT Number: 2012-004878-26 Sponsor Protocol Number: 26842468452 Start Date*: 2013-02-07
    Sponsor Name:Karolinska University Hospital Solna
    Full Title: Antibiotic prophylaxis in patients undergoing primary or secondary breast reconstruction with implants, a randomized parallel two armed prospective clinical trial.
    Medical condition: The incidence of postoperative infections in patients with breast cancer or a history of breast cancer, after elective surgery with primary or secondary first-time breast reconstruction with implan...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Prohibited by CA)
    Trial results: (No results available)
    EudraCT Number: 2012-002222-70 Sponsor Protocol Number: Lidobreast Start Date*: 2013-11-15
    Sponsor Name:University Medical Centre St Radboud
    Full Title: Pilot study: Targeting the inflammatory response after breast cancer surgery with lidocaïne and dexamethasone
    Medical condition: Breast cancer patients who undergo surgery for treatment.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-003115-34 Sponsor Protocol Number: V1 Start Date*: 2012-06-06
    Sponsor Name:Medizinische Universität Wien
    Full Title: A Collagen-Fibrin Patch (Tachosil®) for the Prevention of Symptomatic Lymphoceles after Pelvic Lymphadenectomy in Women with Gynecologic Malignancies: a Randomized Clinical Trial
    Medical condition: endometrial cancer, cervical cancer
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-000135-40 Sponsor Protocol Number: 260585 Start Date*: 2016-05-12
    Sponsor Name:Zealand University Hospital, Department of Surgery
    Full Title: Endoscopic assisted electrochemotherapy in addition to neoadjuvant treatment of locally advanced rectal cancer: a randomized clinical phase II trial.
    Medical condition: Locally advanced rectal cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010033 Colorectal cancer stage II PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010034 Colorectal cancer stage III PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010023 Colorectal neoplasms malignant HLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-005090-20 Sponsor Protocol Number: FADOI.01.2016 Start Date*: 2018-05-17
    Sponsor Name:FONDAZIONE FADOI
    Full Title: Rivaroxaban or placebo for extended antithrombotic prophylaxis after laparoscopic surgery for colorectal cancer: a randomized, double blind, placebo-controlled study. THE PRO-LAPS STUDY II
    Medical condition: Prevention of venous thromboembolism after laparoscopic surgery for colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10067650 Pulmonary embolism prophylaxis LLT
    21.1 100000004865 10012108 Deep venous thrombosis prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-001478-27 Sponsor Protocol Number: IRFMN-GCC-7813 Start Date*: 2019-09-11
    Sponsor Name:Associazione Chirurghi Ospedalieri Italiani
    Full Title: Prophylactic surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC CO2) versus standard surgery in gastric carcinoma at high risk of peritoneal carcinomatosis. Short and long-term outcomes....
    Medical condition: Patients with gastric carcinoma at high risk of developing peritoneal carcinomatosis, suitable to radical surgery.
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10007350 Carcinoma gastric LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-001566-21 Sponsor Protocol Number: 4767 Start Date*: 2018-01-29
    Sponsor Name:Ismail Gögenur [...]
    1. Ismail Gögenur
    2. Ismail Gögenur
    Full Title: Effect of Low-dose Interferon-alfa2a on post-operative immune suppression - a randomized trial
    Medical condition: Colon cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10009944 Colon cancer PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-004567-11 Sponsor Protocol Number: 75911 Start Date*: 2020-12-08
    Sponsor Name:Zealand University Hospital
    Full Title: Effect of Low-dose Interferon-alfa2a on peri operative immune suppression
    Medical condition: pMMR Colon cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10009944 Colon cancer PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-006831-10 Sponsor Protocol Number: 1199.15 Start Date*: Information not available in EudraCT
    Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG
    Full Title: Multicenter, randomised, double-blind Phase III trial to investigate the efficacy and safety of BIBF 1120 in combination with carboplatin and paclitaxel compared to placebo plus carboplatin and pac...
    Medical condition: Advanced ovarian cancer, fallopian tube cancer or primary peritoneal cancer
    Disease: Version SOC Term Classification Code Term Level
    19.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10026469 Malignant neoplasm of specified parts of peritoneum LLT
    19.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10026340 Malignant neoplasm of peritoneum, unspecified LLT
    19.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10016180 Fallopian tube cancer PT
    19.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10033128 Ovarian cancer PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed) FR (Completed) SE (Completed) BE (Completed) PT (Completed) SK (Completed) DK (Completed) AT (Completed) NL (Completed) FI (Completed) PL (Completed) IT (Completed) GR (Completed) CZ (Completed) ES (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-004213-41 Sponsor Protocol Number: RIPAC Start Date*: 2019-06-12
    Sponsor Name:University Hospital Ghent
    Full Title: Effect of intravenous replenishment of iron in the preoperative management of anemia in patients with colon cancer: RIPAC-trial
    Medical condition: M0-stage colon carcinoma with iron deficiency anemia defined by a Hb lower than 13 g/dl in men and 12g/dl in women with a transferrin saturation lower than 20%
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10009964 Colon carcinoma stage 0 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2018-002997-29 Sponsor Protocol Number: D9106C00001 Start Date*: 2019-01-07
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase III, Double-blind, Placebo-controlled, Multi-center International Study of Neoadjuvant/adjuvant Durvalumab for the Treatment of Patients with Resectable Stages II and III Non-small Cell Lun...
    Medical condition: Patients with resectable Non-small Cell Lung Cancer (Stage IIA to IIIB; either squamous or non-squamous)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061873 Non-small cell lung cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Trial now transitioned) AT (Trial now transitioned) BG (Completed) ES (Ongoing) NL (Trial now transitioned) PL (Trial now transitioned) DE (Trial now transitioned) FR (Trial now transitioned) BE (Trial now transitioned) IT (Trial now transitioned) RO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003074-27 Sponsor Protocol Number: SMS-0472B Start Date*: 2018-11-30
    Sponsor Name:WntResearch
    Full Title: A Randomized, Multicentre, Open-Label Controlled Phase II Trial of Foxy-5 as Neo-Adjuvant Therapy in Subjects with Wnt-5a Low Colon Cancer.
    Medical condition: Subjects with resectable adenocarcinoma of the colon and who, at the time of screening, are considered to fulfil the local criteria for adjuvant post-operative chemotherapy. Based on CT/MRI subject...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Temporarily Halted) NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003530-13 Sponsor Protocol Number: 18072011 Start Date*: 2011-12-20
    Sponsor Name:Brighton & Sussex University Hospitals NHS Trust
    Full Title: Randomised phase II window study of short-term preoperative treatment with the PI3K inhibitor GDC-0941 plus Anastrozole versus Anastrozole alone in patients with ER-positive primary breast cancer
    Medical condition: Primary breast cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006206 Breast carcinoma NOS LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-002409-23 Sponsor Protocol Number: 2012/421 Start Date*: 2012-09-21
    Sponsor Name:Aarhus University Hospital
    Full Title: Coagulation Profile in Patients Undergoing Video Assisted Thoracoscopic Surgery (VATS) for lung cancer - a randomized, controlled trial
    Medical condition: Coagulation profile in patients undergoing lung surgery due to cancer in the lung.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10049909 Venous thromboembolism prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-007798-18 Sponsor Protocol Number: AIO/CAO-STO-0801 Start Date*: 2010-07-01
    Sponsor Name:AIO-Studien-gGmbH
    Full Title: An Open Label Randomized Controlled Phase II Trial of Panitumumab in Combination with Epirubicin, Cisplatin and Capecitabine (ECX) versus ECX Chemotherapy alone in Subjects with Locally Advanced Ga...
    Medical condition: Subjects with Locally Advanced Gastric Cancer or Cancer of the Gastroesophageal Junction
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10017758 Gastric cancer PT
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10056267 Gastroesophageal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-000404-11 Sponsor Protocol Number: M20TES Start Date*: 2021-02-02
    Sponsor Name:Princess Margaret Cancer Centre
    Full Title: FIGO 2018 stage IB2 (>2cm - ≤4 cm) Cervical Cancer Treated with Neoadjuvant Chemotherapy Followed by Fertility Sparing Surgery (CoNteSSa) / Neo-Adjuvant Chemotherapy and Conservative Surgery in Cer...
    Medical condition: Women between 18 en 40 years with histologically confirmed invasive cervical cancer with adenocarcinoma, adenosquamous or squamous histology and FIGO 2018 IB2 measuring >2cm to ≤4cm
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-005240-93 Sponsor Protocol Number: 1.3_amendment patientantal Start Date*: 2007-03-13
    Sponsor Name:Karolinska University Hospital
    Full Title: The effect of localanastetic when the drainage is removed, including women operated for breast cancer. [Svensk titel: effekt av lokalbedövning vid dränage borttagning].
    Medical condition: Patients undergoin surgery for breast cancer, according to DSMIV.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000760-18 Sponsor Protocol Number: 13.034 Start Date*: 2014-11-24
    Sponsor Name:Prof. Peter Licht
    Full Title: Supplementary Epidural Analgesia in Video-Assisted Thoracic Surgery (VATS) - The SEAVATS Study.
    Medical condition: Cancer pulmones
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-001191-30 Sponsor Protocol Number: IISR-2015-101127 Start Date*: 2017-04-25
    Sponsor Name:Department of Obstetrics & Gynecology, Copenhagen University Hospital, Rigshospitalet
    Full Title: Use of TachoSil® for the prevention of postoperative complications after groin dissection in vulva cancer patients
    Medical condition: Vulva cancer
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004864 10047750 Vulval neoplasms malignant HLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-001849-15 Sponsor Protocol Number: IFCT-1601 Start Date*: 2016-08-10
    Sponsor Name:IFCT
    Full Title: A PHASE II PROSPECTIVE IMMUNE NEOADJUVANT THERAPY STUDY OF DURVALUMAB (MEDI4736) IN EARLY STAGE NON-SMALL CELL LUNG CANCER
    Medical condition: Stage IB (> 4 cm), II Non Small Cell Lung Cancer resectable
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029517 Non-small cell lung cancer stage I PT
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029518 Non-small cell lung cancer stage II PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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