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Clinical trials for Cardiology

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43893   clinical trials with a EudraCT protocol, of which   7300   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    231 result(s) found for: Cardiology. Displaying page 1 of 12.
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    EudraCT Number: 2021-006550-31 Sponsor Protocol Number: SEC-ES-BempeDACS-2021 Start Date*: 2022-04-05
    Sponsor Name:SPANISH SOCIETY OF CARDIOLOGY
    Full Title: Efficacy and Security of BempeDoic acid in Acute Coronary Syndrome
    Medical condition: Acute coronary syndrome with poor LDL-cholesterol control
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001147-31 Sponsor Protocol Number: 140481 Start Date*: 2013-06-06
    Sponsor Name:Aarhus University Hospital, Department of Cardiology
    Full Title: Aortic Valve Stenosis and Myocardial Efficiency – a Prognostic Marker and a Target for Intervention?
    Medical condition: Aortic stenosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-001905-66 Sponsor Protocol Number: BA-SCAD Start Date*: 2021-07-06
    Sponsor Name:Spanish Cardiology Society
    Full Title: Randomized clinical trial assessing the value of Beta-Blockers and Antiplatelet Agents in patients with Spontaneous Coronary Artery Dissection
    Medical condition: Spontaneous Coronary Artery Dissection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001507-76 Sponsor Protocol Number: BRONCHIOLE2017 Start Date*: 2017-09-20
    Sponsor Name:Region Örebro län
    Full Title: Beta-blockeRs tO patieNts with CHronIc Obstructive puLmonary diseasE (BRONCHIOLE) A pragmatic clinical trial with partial registry-based follow-up
    Medical condition: Chronic Obstructive Pulmonary disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-004571-73 Sponsor Protocol Number: SOCOGAMI Start Date*: 2017-12-15
    Sponsor Name:Karolinska Institutet, Stockholm, Sweden [...]
    1. Karolinska Institutet, Stockholm, Sweden
    2. Karolinska Institutet
    3. Karolinska Institutet
    Full Title: SOdium-glucose CO-transporter inhibition in patients with newly detected Glucose Abnormalities post Myocardial Infarction (SOCOGAMI)
    Medical condition: Patients with acute coronary syndromes (myocardial infarction or unstable angina pectoris) with newly detected glucose perturbations (impaired glucose tolerance or type 2 diabetes)
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2017-002049-31 Sponsor Protocol Number: 15052017 Start Date*: 2017-11-30
    Sponsor Name:Heart Center, Department of Cardiology, Rigshospitalet
    Full Title: Effect of Levosimedan or Placebo on Exercise Capatity and hemodynamics in Patients with Advanced Chronic Heart Failure (LOCO-CHF trial)
    Medical condition: Advanced chronic heart failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-003533-15 Sponsor Protocol Number: LIFE-04-CHF Start Date*: 2018-12-04
    Sponsor Name:Department of Cardiology, Aarhus University Hospital
    Full Title: Clinical and pathophysiological aspects of visualization of metabolic flux in the failing human heart using hyperpolarized [1-13C]-pyruvate cardiac magnetic resonance
    Medical condition: Chronic Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10007540 Cardiac disorder NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000273-13 Sponsor Protocol Number: Start Date*: 2015-03-19
    Sponsor Name:University Hospitals of North Midlands NHS Trust
    Full Title: Mobilisation of endothelial progenitor cells by statin therapy in patients with coronary disease: a proof of concept pilot study.
    Medical condition: 1. New onset angina 2. Acute coronary syndromes (ACS) to include ST elevation ACS and None ST elevation ACS
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003789-15 Sponsor Protocol Number: 9.2 Start Date*: 2019-12-17
    Sponsor Name:Department of Cardiology, Hartcentrum, University Medical Center Groningen
    Full Title: Digoxin Evaluation in Chronic heart failure: Investigational Study In Outpatients in the Netherlands
    Medical condition: Heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-000823-11 Sponsor Protocol Number: TIMO Start Date*: 2023-03-09
    Sponsor Name:Sahlgrenska University Hospital Gothenburg
    Full Title: Ticagrelor monotherapy after coronary stenting in patients with acute myocardial infarction. A prospective single-centre, single-arm phase II study
    Medical condition: Antiplatelet therapy in patients who undergo coronary artery stenting due to coronary artery disease (CAD) or acute coronary syndrome (ACS). The present study will examine whether ticagrelor, as mo...
    Disease: Version SOC Term Classification Code Term Level
    22.1 100000004849 10048560 Coronary artery disease aggravated LLT
    20.0 100000004849 10071111 Non ST segment elevation acute coronary syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002282-30 Sponsor Protocol Number: 2014-2 Start Date*: 2014-07-30
    Sponsor Name:County council of Ostergotland
    Full Title: Effects of oxygen treatment on mechanisms involved in ischemia-reperfusion injury: A pilot study in healthy volunteers.
    Medical condition: Study performed in healthy male vonlunteers.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-002293-28 Sponsor Protocol Number: 2020-002293-28 Start Date*: 2020-05-29
    Sponsor Name:Karolinska University Hospital
    Full Title: Resolving inflammatory storm in COVID-19 patients by Omega-3 polyunsaturated fatty acids. - A single-blind, randomized, placebo-controlled feasibility study
    Medical condition: SARS-COV-2 Infection
    Disease: Version SOC Term Classification Code Term Level
    23.0 100000004862 10084272 SARS-CoV-2 infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-001617-21 Sponsor Protocol Number: 72864 Start Date*: 2020-08-27
    Sponsor Name:Aarhus University Hospital
    Full Title: The Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed with Wild-Type Transthyretin Cardiac Amyloidosis.
    Medical condition: Wild-Type Transthyretin Cardiac Amyloidosis
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005950-57 Sponsor Protocol Number: 2005-07 Start Date*: 2007-03-23
    Sponsor Name:French Society of Cardiology
    Full Title: Assessment of Endothelial VAsomotricity after treatment by Nicotinic Acid in Patients presenting a recent Acute Coronary Syndrome
    Medical condition: acute coronary syndrome under 7 days
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-002242-17 Sponsor Protocol Number: B00844 Start Date*: 2020-07-30
    Sponsor Name:Manchester University NHS Foundation Trust
    Full Title: A randomised, double-blind, placebo-controlled, phase 2 evaluation of the efficacy and mechanism of trientine in patients with hypertrophic cardiomyopathy.
    Medical condition: Hypertrophic Cardiomyopathy (HCM)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10020871 Hypertrophic cardiomyopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2016-002097-13 Sponsor Protocol Number: SI-05-RG-45 Start Date*: 2017-05-15
    Sponsor Name:Department of Cardiology, University Medical Centre Ljubljana
    Full Title: Comparison of modified-release and standard tacrolimus immunosuppression regimens in heart transplant recipients
    Medical condition: Tacrolimus is a potent immunosuppressant agent widely used for the prevention and treatment of rejection in heart transplant recipients. While tacrolimus is typically administered in two divided do...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000204-33 Sponsor Protocol Number: 01 Start Date*: 2006-12-29
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE DI CIRCOLO A.O. DI RILIEVO REGIONALE
    Full Title: REPEATED I.V. BOLUSES FLECAINIDE FOR ACUTE ATRIAL FIBRILLATION TERMINATION A SINGLE BLIND RANDOMIZED REGIMEN CONTROLLED TRIAL.
    Medical condition: ATRIAL FIBRILLATION
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003658 Atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001341-27 Sponsor Protocol Number: Empire-2017 Start Date*: 2017-05-29
    Sponsor Name:Morten Schou
    Full Title: Empagliflozin in heart failure patients with reduced ejection fraction: A randomized clinical trial (Empire HF)
    Medical condition: Heart failure with reduced ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10078289 Heart failure with reduced ejection fraction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2004-005136-76 Sponsor Protocol Number: ASINC101C Start Date*: 2005-05-02
    Sponsor Name:Professor Christina Eintrei,Institution of Medical & Health, Section of Anesthesiology
    Full Title: Aspirin in noncardiac surgery
    Medical condition: Patients with cardiovascular risk factors undergoing elective non-cardiac surgery of high or intermediate risk.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004592-23 Sponsor Protocol Number: DLIFE Start Date*: 2015-03-12
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA PISANA
    Full Title: Phase IV randomized, double blind, placebo-controlled study: role of hypovitaminosis D in heart failure and possible advantages of cholecalciferol (Vit D) administration
    Medical condition: HEART FAILURE
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004849 10011949 Decompensation cardiac LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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