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Clinical trials for Contrast

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    938 result(s) found for: Contrast. Displaying page 1 of 47.
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    EudraCT Number: 2012-003696-18 Sponsor Protocol Number: uni-koeln-1547 Start Date*: 2013-07-25
    Sponsor Name:University of Cologne
    Full Title: Effect of a preinterventional calorie restriction on renal function after contrast agent exposition in patients at risk.
    Medical condition: contrast-induced nephropathy, acute renal failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000712-42 Sponsor Protocol Number: IOM-115 Start Date*: 2004-12-22
    Sponsor Name:Bracco Imaging S.p.A.
    Full Title: Enhacement of the lower extremities computed tomography: IOMERON®-400 VS VISIPAQUE™-320 (ELECTIV).
    Medical condition: subjects with mild to moderate renal impairment (SCr =1.5-2.5 mg/dL and/or calculated CrCl = 10-60 mL/min) who undergo clinically-indicated IV contrast-enhanced MDCTA scanning of the lower extremit...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) SE (Completed) GB (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-000681-22 Sponsor Protocol Number: VIS-13-08 Start Date*: 2015-02-25
    Sponsor Name:ErasmusMC
    Full Title: EFFECT OF ISO-OSMOLAR CONTRAST MEDIUM ON CORONARY OPACIFICATION AND HEART RHYTHM IN CORONARY CT ANGIOGRAPHY (ISO-COR)
    Medical condition: Patients with suspected coronary artery disease and clinically referred for coronary CTA.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003946-18 Sponsor Protocol Number: GDX-44-011 Start Date*: 2019-05-03
    Sponsor Name:GUERBET
    Full Title: Efficacy and safety of gadopiclenol for body magnetic resonance imaging (MRI)
    Medical condition: Patients presenting with know or suspected enhancing abnormality(ies) and/or lesion(s) in at least one body region among head & neck, thorax (including breast), abdomen (including liver, pancreas a...
    Disease: Version SOC Term Classification Code Term Level
    20.1 10022891 - Investigations 10059696 Scan with contrast PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) HU (Completed) BG (Completed) DE (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-001673-40 Sponsor Protocol Number: 2015/96 Start Date*: 2015-06-29
    Sponsor Name:Oslo University Hospital
    Full Title: INTRATHECAL CONTRAST-ENHANCED MAGNETIC RESONANCE IMAGING
    Medical condition: Cerebrospinal fluid circulation disorder seen in the following clinical disease states: Communicating hydrocephalus, idiopathic intracranial hypertension, idiopathic intracranial hypotension, intra...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-005172-17 Sponsor Protocol Number: CHARITE-WKD-2005-1 Start Date*: 2005-09-09
    Sponsor Name:Charité/Campus Virchow-Klinikum, Medizinische Klinik m. S. Kardiologie
    Full Title: Renal haemodynamics during application of contrast media in patients undergoing cardiac catheterisation with high risk of acute renal failure: randomized comparison of different contrast media
    Medical condition: Patients with allready existing chronic renal failure undergoing a cardiac catheterisation for clinical reasons may develope an acute renal failure due to radio contrast media. This trial compares...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-000952-32 Sponsor Protocol Number: BAY86-4873/16078 Start Date*: 2015-09-24
    Sponsor Name:Bayer HealthCare AG
    Full Title: Open-label, multi-center study to evaluate the safety, efficacy, and plasma gadolinium concentrations after an intravenous injection of 0.1 mL/kg body weight Eovist/Primovist for enhanced magnetic ...
    Medical condition: Magnetic Resonance Imaging
    Disease: Version SOC Term Classification Code Term Level
    18.0 10022891 - Investigations 10072304 Nuclear magnetic resonance imaging liver PT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2007-002888-27 Sponsor Protocol Number: KKB 001 20-05-2007 Start Date*: 2007-10-08
    Sponsor Name:Knappschaftskrankenhaus Bochum
    Full Title: Intra-individual, randomized comparison of the MRI contrast agents Gadovist® 1.0 versus Prohance® in patients with primary and secondary brain tumors, evaluated in a blinded read
    Medical condition: Primary and secondary brain tumors
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-006724-35 Sponsor Protocol Number: fMRI-CA_2008 Start Date*: 2008-09-08
    Sponsor Name:CMIV
    Full Title: Functional MRI after administration of Gd-based blood pool contrast agents
    Medical condition: This study aims to investigate the possibility to obtain higher functional contrast and better spatial assessment in contrast enhanced functional Magnetic Resonance Imaging (fMRI) as compared to st...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029820 Nuclear magnetic resonance imaging gadolinium-enhanced LLT
    9.1 10029817 Nuclear magnetic resonance imaging brain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-005542-42 Sponsor Protocol Number: 2020/11 Start Date*: 2021-03-11
    Sponsor Name:Region Västerbotten
    Full Title: Intrathecal contrast-enhanced MRI for investigation of cerebrospinal fluid transportation
    Medical condition: Cerebrospinal fluid circulation disorder seen in clinically suspected idiopathic normal pressure hydrocephalus
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-001710-19 Sponsor Protocol Number: LUMINALSONAZOID001 Start Date*: 2022-11-01
    Sponsor Name:Medical department, Haukeland University Hospital
    Full Title: Sonographic diagnostics with oral contrast for Crohns. A novel method for detecting Crohns disease using sonographic intraluminal contrast.
    Medical condition: Crohns disease in the terminal ileum
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-021526-36 Sponsor Protocol Number: LMU_Rad_MR_GadoMRA01 Start Date*: 2011-04-07
    Sponsor Name:Klinikum der Universität München
    Full Title: Dynamic and high-resolution MR angiography of the supraaortic vessels at 3 Tesla: Performance of Gadobutrol (Gadovist) in comparison to Gedobenate Dimeglumine (Multihance) and Gadoterate Meglumine ...
    Medical condition: Supraaortic vessel disease; suspicion or proven carotid artery stenosis / stenoses
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029205 - Nervous system disorders 10007687 Carotid artery stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000711-26 Sponsor Protocol Number: IOM-114 Start Date*: 2004-12-22
    Sponsor Name:Bracco Imaging S.p.A.
    Full Title: ABDOMINAL COMPUTED TOMOGRAPHY: IOMERON®400 VS VISIPAQUE™320 ENHANCEMENT (ACTIVE).
    Medical condition: subjects with mild to moderate renal impairment scheduled to undergo clinically-indicated IV contrast –enhanced MDCT scanning of the liver
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) SE (Prematurely Ended) GB (Prematurely Ended) IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-002368-42 Sponsor Protocol Number: LUM-001 Start Date*: 2017-10-12
    Sponsor Name:Lument AB
    Full Title: An open, randomized, controlled, single centre trial to evaluate CT image quality and diagnostic feasibility of Lumentin® 44, a new egg albumen based oral bowel filling agent, in comparison with di...
    Medical condition: None. Lumentin 44 is a contrast agent and the contrast properties will be investigated in this trial. Patients referred to computerised tomography of the abdomen will be included in the trial. Nei...
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004848 10011603 CT scan LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-022570-13 Sponsor Protocol Number: GAD-1140-WIL-0020-I Start Date*: Information not available in EudraCT
    Sponsor Name:Medizinsiche Fakultät der Technischen Universität München
    Full Title: Gadovit-Studie Intraindividueller Vergleich der diagnostischen Wertigkeit von delayed-enhancement imaging mit Gadobutrol (Gadovist®) versus Gadobenat Dimeglumin (Multihance®) mittels einer MRT Bi...
    Medical condition: Rupture of a thrombotic plaque within a coronary artery leads to a complete or incomplete occlusion of the vessel with subsequent ischemia in the affected myocardium. If not revascularised within ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-000630-35 Sponsor Protocol Number: Start Date*: 2013-10-07
    Sponsor Name:Alder Hey Children's NHS Foundation Trust
    Full Title: Pilot study on use of Sulphur hexafluoride Microbubbles (SonoVue®) as a Magnetic Resonance Imaging contrast agent in the imaging of brain tumours.
    Medical condition: Patients undergoing pre-operative/follow up MRI investigation for a known enhancing brain tumour
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2004-002053-31 Sponsor Protocol Number: ALEC4005 Start Date*: 2005-08-16
    Sponsor Name:Hammersmith Hospital
    Full Title: To determine the diagnostic accuracy of MRI in detecting lymph node metastases using USPIO (Ultra small super-paramagnetic iron oxide particles) in patients with gynecological malignancy
    Medical condition: Gynaecological malignancies
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-003327-21 Sponsor Protocol Number: OCAPCT-1 Start Date*: 2007-11-01
    Sponsor Name:Heart of England NHS Foundation Trust Radiology Department
    Full Title: Oral Contrast Agent for Elective Abdominopelvic CT: Water versus Dilute Gastrografin
    Medical condition: No specific medical condition to be investigated. The trial is to look at physical and radiological characteristic of contrast agent and how it improves interpretation of CT scan.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003197-26 Sponsor Protocol Number: IOM-120 Start Date*: 2008-05-29
    Sponsor Name:BRACCO IMAGING
    Full Title: Studio randomizzato di fase IV, doppio cieco, multicentrico, per il confronto di Iomeron 400 con Visipaque 320 nell'angiografia coronarica con Tomografia Computerizzata a doppio tubo (DS-CTA)
    Medical condition: CAD
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011085 Ischaemic coronary artery disorders HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-004222-24 Sponsor Protocol Number: GUF 001 Start Date*: 2008-03-10
    Sponsor Name:Dekan des FB Medizin der Johann-Wolfgang Goethe-Universität
    Full Title: Intra-individual, randomized comparison of the MRI contrast agents Gadovist 1.0 versus Dotarem when imaging the pelvis in patients with spondylarthritides, evaluated in a blinded read
    Medical condition: Polyarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10046107 Unspecified polyarthropathy or polyarthritis involving pelvic region and thigh LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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