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Clinical trials for Coughing

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    162 result(s) found for: Coughing. Displaying page 1 of 9.
    1  2  3  4  5  6  7  8  9  Next»
    EudraCT Number: 2005-003249-15 Sponsor Protocol Number: E-BRO-3 Start Date*: 2005-09-26
    Sponsor Name:BIONORICA AG
    Full Title: Efficacy and tolerability of Bronchipret® Saft for the treatment of acute bronchitis in adults A randomized, double-blind, placebo-controlled, parallel-group, multicenter Phase IV study.
    Medical condition: Acute bronchitis with productive cough i.e. onset of bronchial mucus production with impaired ability to cough up.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000330-13 Sponsor Protocol Number: E-BRO-4 Start Date*: 2006-09-18
    Sponsor Name:Bionorica AG
    Full Title: Efficacy and tolerability of Bronchipret® TP film coated tablets for the treatment of acute bronchitis in adults.
    Medical condition: Acute bronchitis with productive cough i.e. onset of bronchial mucus production with impaired ability to cough up.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10006452 Bronchitis acute LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-004143-11 Sponsor Protocol Number: 33103 Start Date*: 2008-12-17
    Sponsor Name:The University of Nottingham
    Full Title: Are macrolide antibiotics effective in chronic idiopathic cough?
    Medical condition: idiopathic chronic cough, defined as cough with no identifiable cause and which has been present for at least 2 monhs.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011224 Cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-000866-11 Sponsor Protocol Number: 7164-L-01 Start Date*: 2004-08-06
    Sponsor Name:ZAMBON GROUP
    Full Title: A multicenter, randomized, parallel group, controlled, double-blind study to evaluate efficacy and safety of pholcodine as antitussive agent vs dextrometorphan in non-productive cough
    Medical condition: Symptomatic treatment of non productive cough
    Disease: Version SOC Term Classification Code Term Level
    6.1 10011224 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-006278-22 Sponsor Protocol Number: ORV-PF-01 Start Date*: 2022-08-29
    Sponsor Name:NeRRe Therapeutics Ltd
    Full Title: A DOUBLE-BLIND, RANDOMISED, PLACEBO CONTROLLED, TWO PERIOD CROSS-OVER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ORVEPITANT IN CHRONIC COUGH IN PATIENTS WITH IDIOPATHIC PULMONARY FIBROSIS
    Medical condition: Chronic cough in patients with idiopathic pulmonary fibrosis
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004855 10066656 Chronic cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004463-39 Sponsor Protocol Number: 221921 Start Date*: 2019-03-06
    Sponsor Name:Sahlgrenska University Hospital, Department of Internal Medicine/Respiratory Medicine and Allergology [...]
    1. Sahlgrenska University Hospital, Department of Internal Medicine/Respiratory Medicine and Allergology
    2. University of Gothenburg
    Full Title: Influence on cough and airway symptoms by oral capsaicin (capscium oleoresin ) – a phase II, randomised, placebo-controlled clinical study in patients with chronic idiopathic cough
    Medical condition: Chronic idiopathic cough
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-003478-22 Sponsor Protocol Number: P2202GF Start Date*: 2023-02-17
    Sponsor Name:G. Pohl-Boskamp GmbH & Co. KG
    Full Title: A randomised, placebo-controlled, double-blind parallel-group trial to assess the efficacy and safety of PB432 in outpatients with COVID-19 induced acute respiratory infection - COVARI-2 study-
    Medical condition: COVID-19 with acute respiratory infection
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004862 10084401 COVID-19 respiratory infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000473-38 Sponsor Protocol Number: EA-08-1-34 Start Date*: 2008-09-12
    Sponsor Name:Engelhard Arzneimittel GmbH & Co. KG
    Full Title: Prospan® Hustenzäpfchen – Investigation on efficacy and tolerability in children: A double-blind, placebo controlled, randomised, multi-centre, comparative study with parallel groups for the sympto...
    Medical condition: Acute bronchitis accompanied by coughing
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006452 Bronchitis acute PT
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022819-19 Sponsor Protocol Number: P1001GF Start Date*: 2010-12-10
    Sponsor Name:G. Pohl-Boskamp GmbH & Co. KG
    Full Title: Efficacy, safety and tolerability of two weeks treatment with SIA capsules in acute bronchitis - A multi-centre, randomised, placebo-controlled, double-blind, parallel-group trial -
    Medical condition: acute bronchitis
    Disease: Version SOC Term Classification Code Term Level
    13.1 10021881 - Infections and infestations 10000687 Acute bronchitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-016778-34 Sponsor Protocol Number: TH09001 Start Date*: 2010-01-27
    Sponsor Name:THERABEL LUCIEN PHARMA
    Full Title: Evaluation de la non-infériorité de l’efficacité d’Helicidine® versus Sirop à base de dextromethorphane sur la toux sèche des patients pris en charge en médecine générale.
    Medical condition: Patients volontaires présentant un épisode de toux sèche et venant consulter en médecine générale.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10013773 Dry cough LLT
    12.1 10011224 Cough LLT
    12.1 10011233 Coughing and associated symptoms HLT
    12.1 10038716 Respiratory disorders NEC HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-003237-11 Sponsor Protocol Number: TMP-2005-2020-36 Start Date*: 2021-11-11
    Sponsor Name:Fraunhofer Gesellschaft for its Institute for translationale Medicine and Pharmacology ITMP
    Full Title: Effect of Bronchipret on antiviral immune response in patients with mild COVID-19 (BroVID)
    Medical condition: Adult patients suffering from mild COVID-19 with cough and at least one other symptoms will be recruited for this study.
    Disease: Version SOC Term Classification Code Term Level
    23.0 100000004862 10084272 SARS-CoV-2 infection LLT
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10011224 Cough PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005794-31 Sponsor Protocol Number: VRP700-002-2012 Start Date*: 2013-03-25
    Sponsor Name:Verona Pharma plc
    Full Title: A randomised, double-blind, placebo-controlled crossover study to assess the efficacy of a single dose of 100mg of VRP700 by inhalation in reducing the frequency and severity of cough in adult pati...
    Medical condition: Chronic cough in Idiopathic Pulmonary Fibrosis
    Disease: Version SOC Term Classification Code Term Level
    16.1 10038738 - Respiratory, thoracic and mediastinal disorders 10066656 Chronic cough LLT
    16.1 10038738 - Respiratory, thoracic and mediastinal disorders 10011224 Cough PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2006-004102-13 Sponsor Protocol Number: AcadMed CTU210406 Start Date*: 2006-10-16
    Sponsor Name:Hull and east yorkshire Hospitals Trust
    Full Title: An 8 week, non-selected, cohort, study to investigate whether the treatment of reflux induced cough alters associated bronchial hyperresponsiveness.
    Medical condition: Bronchial hyper-responsiveness in relation to reflux associated chronic cough
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011233 Coughing and associated symptoms HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-017420-75 Sponsor Protocol Number: SM1-plp-09 Start Date*: 2010-01-25
    Sponsor Name:Joergen B Dahl
    Full Title: Effekten af transversus abdominis plane (TAP) blok på patienter, der får foretaget laparoskopisk cholcystektomi i dagkirurgisk regi
    Medical condition: Postoperative pain in patients undergoing laparoscopic cholecystectomy
    Disease: Version SOC Term Classification Code Term Level
    12.1 10036236 Postoperative pain relief LLT
    12.1 10036276 Postoperative analgesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001665-25 Sponsor Protocol Number: 1 Start Date*: 2018-10-23
    Sponsor Name:Erasmus MC
    Full Title: Formoterol-beclomethasone in patients with bronchiectasis: a randomized, double-blind, placebo-controlled trial (Forza study)
    Medical condition: Bronchiectasis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000139-28 Sponsor Protocol Number: 12_DOG07_146 Start Date*: 2013-03-22
    Sponsor Name:The Christie NHS Foundation Trust
    Full Title: A single arm double-blind placebo controlled cross-over trial of Aprepitant for the treatment of cough in lung cancer: “CALC” Trial
    Medical condition: Cough relating to lung cancer
    Disease: Version SOC Term Classification Code Term Level
    15.1 100000004864 10025044 Lung cancer LLT
    15.1 10038738 - Respiratory, thoracic and mediastinal disorders 10011224 Cough PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005533-38 Sponsor Protocol Number: ABR 14828 Start Date*: 2007-06-28
    Sponsor Name:there is no sponsor.
    Full Title: 'Studies in patients with chronic cough; montelukast and amitriptyline studies’.
    Medical condition: Chronic cough ( cough lasting > 8 weeks).
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004160-67 Sponsor Protocol Number: Protocol F1J-MC-SBCT (a) Start Date*: 2005-02-24
    Sponsor Name:Eli Lilly and Company Limited
    Full Title: Effect of Duloxetine on Valsalva Leak Point Pressure and Quantitative Rhabdosphincter Electromyography Measures in Women with Stress Urinary Incontinence
    Medical condition: stress urinary incontinence
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-004715-27 Sponsor Protocol Number: NOC100-C-201 Start Date*: 2021-02-03
    Sponsor Name:Nocion Therapeutics, Inc.
    Full Title: A Phase 2a, Randomised, Double-Blind, Placebo-Controlled, Two-Part Study to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetic Profiles of Inhaled Doses of NOC-100 in Adult Participants...
    Medical condition: Cough
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10011224 Cough PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005151-13 Sponsor Protocol Number: MEM-COUGH-01 Start Date*: 2012-05-17
    Sponsor Name:University of Manchester [...]
    1. University of Manchester
    2. University Hospital of South Manchester
    Full Title: Open-label Pilot Study of Memantine in Chronic Cough Patients Attending a Specialist Clinic
    Medical condition: Idiopathic and treatment resistant Chronic Cough
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004855 10066656 Chronic cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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