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Clinical trials for Deformation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    16 result(s) found for: Deformation. Displaying page 1 of 1.
    EudraCT Number: 2016-005049-21 Sponsor Protocol Number: MRZ-R-201212_01001_N_2 Start Date*: 2017-01-12
    Sponsor Name:LLC Merz Pharma, Russia
    Full Title: Multi-center Open Comparative Randomized Trial of Clinical and Neurophysiological Efficacy and Safety of Xeomin (Botulinum Toxin Type A) vs. Botox (Complex of Botulinum Toxin Type A and Hemaggluti...
    Medical condition: • Cerebral Palsy • Spastic Paraplegia and Hemiparesis • Equine and Equinovarus Foot Deformation
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2018-001488-21 Sponsor Protocol Number: EST:15/17 Start Date*: 2018-11-06
    Sponsor Name:Sergio Aleman
    Full Title: EFFECT OF VITAMIN D SUPPLEMENTATION ON THE VENTRICULAR DEFORMATION RATE (STRAIN RATE) IN PATIENTS WITH HEART FAILURE WITH PRESERVED OR MODERATELY REDUCED EYECTION FRACTION
    Medical condition: Heart failure with preserved or moderately reduced eyection fraction
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-000416-24 Sponsor Protocol Number: CRC-ACNE-A-05 Start Date*: 2013-06-21
    Sponsor Name:Charité-Universitätsmedizin Berlin, Department of Dermatology, Clinical Research Center for Hair and Skin Science
    Full Title: THE EFFECT OF AZELAIC ACID ON SYMPTOMS OF ACNE IN FEMALE PATIENTS AGE 20-45 WITH MILD TO MODERATE PAPULOPUSTULAR ACNE (ACNE TARDA)
    Medical condition: MILD TO MODERATE PAPULOPUSTULAR ACNE (ACNE TARDA)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-001005-27 Sponsor Protocol Number: 1818 Start Date*: 2011-05-02
    Sponsor Name:Department of Anaesthesiology, University Hospital of Skejby
    Full Title: The effect of dobtutamin on postoperative systolic deformation and diastolic function in patients with concentric hypertrophy of the left ventricle
    Medical condition: Aortic stenosis Diastolic dysfunction
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10002907 Aortic stenosis & incompetence LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-000479-40 Sponsor Protocol Number: D1449L00030 Start Date*: 2007-09-12
    Sponsor Name:Department of Psychiatry, RWTH Aachen
    Full Title: Effects of quetiapine on ultrastructural hippocampal and neurochemical changes in patients with bipolar disorder: searching for the antidepressant and mood stabilising neurophysiology
    Medical condition: Bipolar disorder is a common psychiatric disorder which is characterised by manic and depressive states. The mood stabilizing effect of novel antipsychotics seems to be modulation of neuronal plast...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000915-26 Sponsor Protocol Number: CMMo-OCC-2012 Start Date*: 2013-09-17
    Sponsor Name:FUNDACIÓN PROGRESO Y SALUD
    Full Title: Clinical Trial Phase III single-center, open-label efficacy of intracoronary infusion of bone marrow mononuclear cells in patients with occlusion Autologous chronic coronary revascularization and v...
    Medical condition: Chronic coronary occlusion
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10011086 Coronary artery occlusion PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Temporarily Halted)
    Trial results: View results
    EudraCT Number: 2012-005313-39 Sponsor Protocol Number: LAN-HD-ACRO Start Date*: 2013-05-17
    Sponsor Name:AZIENDA OSPEDALIERA Spedali Civili di Brescia
    Full Title: Scheme of treatment with high-dose lanreotide in acromegalic patients poorly responsive to treatment with standard doses."
    Medical condition: acromegaly
    Disease: Version SOC Term Classification Code Term Level
    14.1 10014698 - Endocrine disorders 10000599 Acromegaly PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-018490-38 Sponsor Protocol Number: 1616 Start Date*: 2010-06-14
    Sponsor Name:Anæstesiologisk Afd. I, Skejby Sygehus
    Full Title: Effekten af levosimendan på systolisk deformation og diastolisk funktion hos patienter med operationskrævende aortastenose og svær hypertrofi af venstre ventrikel
    Medical condition: Aortaklapsstenose Diastolisk dysfunktion
    Disease: Version SOC Term Classification Code Term Level
    12.1 10002906 Aortic stenosis LLT
    12.1 10052337 Diastolic dysfunction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-006166-42 Sponsor Protocol Number: RIVA Start Date*: 2007-07-17
    Sponsor Name:University of Tuebingen
    Full Title: Exelon bei dementiellem Syndrom bei Patienten mit Progressiver Supranukleärer Parese - offene, prospektive Phase II-Studie -
    Medical condition: Progressive supranuclear palsy (PSP) is a neurodegenerative disorder with hardly any therapeutical option to ameliorate the course of the disease. Results of first trials with physostigmine and don...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003594-17 Sponsor Protocol Number: NL59077.018.16 Start Date*: 2018-05-28
    Sponsor Name:AMC
    Full Title: Effects of a single denosumab injection on reduction of total contact cast treatment and consolidation of bonefractures caused by acute Charcotfoot in patients with diabetes mellitus (CHARCOT st...
    Medical condition: charcot foot
    Disease: Version SOC Term Classification Code Term Level
    20.1 10027433 - Metabolism and nutrition disorders 10012607 Diabetes mellitus inadequate control PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-005394-66 Sponsor Protocol Number: ESR-20-21070 Start Date*: 2022-02-21
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA SENESE
    Full Title: Effects of Dapagliflozin on cardiac deformation and clinical outcomes in heart failure with reduced and mildly reduced ejection fraction
    Medical condition: heart failure with left ventricular ejection fraction <50%
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10024102 Left cardiac failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-002960-29 Sponsor Protocol Number: 79048 Start Date*: 2020-02-18
    Sponsor Name:Merete Haedersdal [Bispebjerg Hospital]
    Full Title: Assessing the efficacy of image-guided laser-assisted Enstilar® delivery for treatment of psoriatic nails - a proof-of-concept, single-center, prospective, open-label, randomized, clinical trial wi...
    Medical condition: Nail psoriasis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10065874 Psoriatic conditions HLT
    20.0 10040785 - Skin and subcutaneous tissue disorders 10037153 Psoriasis PT
    21.1 10028395 - Musculoskeletal and connective tissue disorders 10037162 Psoriatic arthropathy PT
    20.0 10040785 - Skin and subcutaneous tissue disorders 10028703 Nail psoriasis PT
    22.0 10040785 - Skin and subcutaneous tissue disorders 10028691 Nail discoloration LLT
    21.1 10040785 - Skin and subcutaneous tissue disorders 10006373 Brittle nails LLT
    20.0 10040785 - Skin and subcutaneous tissue disorders 10028689 Nail changes LLT
    20.0 10040785 - Skin and subcutaneous tissue disorders 10028690 Nail deformation LLT
    21.1 10040785 - Skin and subcutaneous tissue disorders 10049281 Nail loss LLT
    20.0 10040785 - Skin and subcutaneous tissue disorders 10064253 Nail pain LLT
    21.1 10040785 - Skin and subcutaneous tissue disorders 10064768 Nail growth increased LLT
    21.1 10040785 - Skin and subcutaneous tissue disorders 10065260 Splitting nails LLT
    21.0 10040785 - Skin and subcutaneous tissue disorders 10069831 Broken nails LLT
    21.0 10040785 - Skin and subcutaneous tissue disorders 10072708 Nail bed hemorrhage LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-002636-25 Sponsor Protocol Number: RG_13-013NS Start Date*: 2013-09-11
    Sponsor Name:University of Birmingham
    Full Title: A Randomised Multicentre Open Label Blinded End Point Trial to Compare the Effects of Spironolactone to Chlortalidone on Left Ventricular Mass and Arterial Stiffness in Stage 3 Chronic Kidney Disease
    Medical condition: The condition under investigation is the disease changes that occur in patients with mild kidney disease that cause them to have a high rate of diseases such as heart failure, rhythm disturbance an...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-003273-42 Sponsor Protocol Number: 14AOI11 Start Date*: 2014-12-23
    Sponsor Name:CHU de Nice
    Full Title: Comparing a diuretic vascular filling in the initial management of acute pulmonary embolism with right ventricular dysfunction normotensive
    Medical condition: acute pulmonary embolism with right ventricular dysfunction normotensive
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004855 10050071 Embolism lung LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-006953-77 Sponsor Protocol Number: 27-12-2021 Start Date*: 2022-04-11
    Sponsor Name:Aarhus University Hospital
    Full Title: Treatment effects of Bisoprolol and Verapamil in symptomatic patients with non-obstructive hypertrophic cardiomyopathy
    Medical condition: Non-obstructive Hypertrophic cardiomyopathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007636 Cardiomyopathy PT
    20.0 10007541 - Cardiac disorders 10049813 Non-obstructive cardiomyopathy PT
    27.0 10010331 - Congenital, familial and genetic disorders 10020871 Hypertrophic cardiomyopathy PT
    20.0 10007541 - Cardiac disorders 10061029 Cardiomyopathy primary LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-004455-32 Sponsor Protocol Number: IMB101-006 Start Date*: 2021-02-16
    Sponsor Name:Imbria Pharmaceuticals, Inc.
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Exploratory Study on the Safety, Tolerability, and Pharmacodynamics of IMB-1018972 in Patients with Angina due to Coronary Syndrome
    Medical condition: Stable coronary artery disease (CAD) /Chronic coronary syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) FI (Completed) DK (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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