Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Diamorphine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    12 result(s) found for: Diamorphine. Displaying page 1 of 1.
    EudraCT Number: 2009-014982-16 Sponsor Protocol Number: DIA002 Start Date*: 2010-02-25
    Sponsor Name:Wockhardt UK Limited
    Full Title: An open label, single dose safety study of Diamorphine Hydrochloride Nasal Spray (0.1mg/kg) in children
    Medical condition: The IMP is to be used as an analgesic for the relief of acute pain.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10002182 Analgesia LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-003250-18 Sponsor Protocol Number: P010606 Start Date*: 2007-04-05
    Sponsor Name:Poole Hospital NHS Trust
    Full Title: A two-centred randomised double blind controlled trial comparing intramuscular diamorphine and intramuscular pethidine for labour analgesia
    Medical condition: pain relief during active labour
    Disease: Version SOC Term Classification Code Term Level
    8.1 10029772 Normal pregnancy, labour and delivery HLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-014983-20 Sponsor Protocol Number: DIA001 Start Date*: 2010-02-25
    Sponsor Name:Wockhardt UK Limited
    Full Title: An open label single dose pharmacokinetic study of Diamorphine Hydrochloride Nasal Spray (0.06mg/kg) in children
    Medical condition: The IMP is to be used as an analgesic for the relief of acute pain.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10002182 Analgesia LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-001877-34 Sponsor Protocol Number: HOT-Treated Start Date*: 2016-11-25
    Sponsor Name:South London and Maudsley NHS Foundation Trust [...]
    1. South London and Maudsley NHS Foundation Trust
    2. King's College London
    Full Title: Improving understanding of Heroin Overdose Testing: diamorphine dose-escalation testing in a treated population
    Medical condition: Opioid Overdose
    Disease: Version SOC Term Classification Code Term Level
    21.1 10022117 - Injury, poisoning and procedural complications 10033295 Overdose PT
    20.0 10022117 - Injury, poisoning and procedural complications 10033299 Overdose effect LLT
    20.1 10022117 - Injury, poisoning and procedural complications 10067695 Acute overdose LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-019026-13 Sponsor Protocol Number: TADAM_Ulg Start Date*: 2010-05-06
    Sponsor Name:University of Liège
    Full Title: TADAM, a Belgian project of Heroin-Assisted Treatment
    Medical condition: treatment resistant heroin addiction
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004278-10 Sponsor Protocol Number: 2004/R/AN/04 Start Date*: 2005-02-10
    Sponsor Name:Lothian Health Board- University Hospitals Division [...]
    1. Lothian Health Board- University Hospitals Division
    2. Lothian Health Board University Hospitals Division
    Full Title: Determination of the subarachnoid ED50 and ED95 of hyperbaric 0.5% bupivacaine when co-administered with diamorphine hydrochloride for caesarean section
    Medical condition: patients undergoing elective caesarean section
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-003175-36 Sponsor Protocol Number: KCL/SLaM-CT2004-3 Start Date*: 2007-07-26
    Sponsor Name:Kings College London/South London and Maudsley NHS Foundation Trust
    Full Title: Randomised controlled trial of injectable opioid treatment for heroin dependence (RIOTT)
    Medical condition: Opioid dependence, ICD classification code F11.2 (ICD-10)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-007053-51 Sponsor Protocol Number: 003/APR06 Start Date*: 2007-07-02
    Sponsor Name:Gloucestershire Hospitals NHS Foundation Trust
    Full Title: Diamorphine or alfentanil for subcutaneous use in hospice in-patients
    Medical condition: Palliative Care
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059513 Palliative care LLT
    9.1 10059513 Palliative care PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-002229-23 Sponsor Protocol Number: RB-UK-11-0018 Start Date*: 2012-05-09
    Sponsor Name:RB Pharmaceuticals Inc.
    Full Title: A randomised, double blind, placebo controlled, cross over study of the effects of Buprenorphine Hemiadipate Hydrochloride/Naloxone Hydrochloride Dihydrate intravenous challenges in opioid dependen...
    Medical condition: Maintenance/substitution agent for the treatment of opioid dependence.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10037175 - Psychiatric disorders 10012346 Dependence on opiates LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-004620-12 Sponsor Protocol Number: dyspnoea1 Start Date*: 2005-01-14
    Sponsor Name:Royal Marsden Hospital
    Full Title: Assessment of normal release morphine in the management of dyspnoea
    Medical condition: Breathlessness of any cause in cancer patients are identified and treated with normal release morphine which has been shown to be both effective and safe.The idea of the trial is to see if there wi...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-002308-40 Sponsor Protocol Number: IN Morphine II Start Date*: 2005-08-19
    Sponsor Name:University of Plymouth
    Full Title: Evaluation of Intranasal (IN) Morphine Sulphate as a Paramedic Administered Analgesic for Children in the Pre-Hospital Environment
    Medical condition: This research hopes to bridge the gap between in-hospital diamorphine and pre-hospital IV morphine by developing IN morphine for administration to children between 3 and 14 years old. This will all...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2013-005009-30 Sponsor Protocol Number: Start Date*: 2016-05-04
    Sponsor Name:Gloucestershire Hospitals NHS Foundation Trust and
    Full Title: An open label, randomised controlled feasibility pilot study to evaluate whether nasal fentanyl alone and in combination with buccal midazolam give better symptom control to dying patients when com...
    Medical condition: Adult hospice in-patients with terminal cancer who are thought to be in the last 1 - 2 weeks of life
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10059513 Palliative care PT
    20.0 100000004864 10048683 Advanced cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Sat May 03 07:13:41 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA