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Clinical trials for Doxapram

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44364   clinical trials with a EudraCT protocol, of which   7388   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    5 result(s) found for: Doxapram. Displaying page 1 of 1.
    EudraCT Number: 2012-001849-41 Sponsor Protocol Number: DOX-101 Start Date*: 2012-06-18
    Sponsor Name:Leids Universitair Medisch Centrum (LUMC)
    Full Title: Two-part, Randomized, Placebo-controlled, Repeated Stepped Infusion Dose Study of the Pharmacodynamics of Doxapram when Co-administered with Opioids (Protocol – doxapram-101).
    Medical condition: acute respiratory insufficiency, including such conditions as opioid and anesthetic-induced respiratory depression, post-anesthetic atelectasis, and central apneas (e.g., apnea of prematurity).
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10038738 Respiratory, thoracic and mediastinal disorders SOC
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002979-17 Sponsor Protocol Number: K620 Start Date*: 2018-12-17
    Sponsor Name:Ruprecht-Karls University Heidelberg Medical Faculty, University Hospital
    Full Title: Use of doxapram as a new antiarrhythmic drug for a specific therapy of atrial fibrillation
    Medical condition: Paroxysmal or persistent, non-valvular, atrial fibrillation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    20.0 10007541 - Cardiac disorders 10034039 Paroxysmal atrial fibrillation LLT
    20.0 10007541 - Cardiac disorders 10071667 Persistent atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-003666-41 Sponsor Protocol Number: MEC2020-0078 Start Date*: 2020-04-21
    Sponsor Name:Erasmus MC University Medical Center
    Full Title: Doxapram versus placebo in preterm newborns: an international double blinded multicenter randomized controlled trial.
    Medical condition: Preterm infants are at high risk of respiratory failure due to immaturity of the respiratory system. Respiratory failure is caused by a comprised lung function and impaired control of breathing. Co...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10077323 Infantile mixed apnea LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: NL (Trial now transitioned) BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-003873-85 Sponsor Protocol Number: PCS02 Start Date*: 2016-04-12
    Sponsor Name:Helsinki University Central Hospital
    Full Title: Doxapram as an Additive to Propofol Sedation in Sedation for ERCP - a Placebo controlled, randomized, double-blinded, prospective study
    Medical condition: Respiratory depression caused by propofol sedation during an ERCP procedure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2007-002567-27 Sponsor Protocol Number: CTU 011 B Start Date*: 2008-11-04
    Sponsor Name:RIEMSER Arzneimittel AG
    Full Title: CLINICAL PHASE III MULTI-CENTRIC, DOUBLE-BLIND, DOUBLE DUMMY, RANDOMISED STUDY TO COMPARE SAFETY AND EFFICACY OF DOPRAM® (DOXAPRAM HYDROCHLORIDE) TO CAFEINE COOPER (CAFFEINE CITRATE) IN THE TREATME...
    Medical condition: Premature infants with a corrected gestational age of 25;0 to 30;6 weeks with a immature central nervous system resulting in frequent apnoeic episodes
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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