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Clinical trials for Effusion

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    383 result(s) found for: Effusion. Displaying page 1 of 20.
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    EudraCT Number: 2007-006051-39 Sponsor Protocol Number: KKS-110 Start Date*: 2008-03-12
    Sponsor Name:Philipps Universität Marburg
    Full Title: Pharmakokinetic investigation on the tissue penetration of moxifloxacin within the pericardial space
    Medical condition: Patients with chronic pericardial effusion , 5 of them with pericardial effusion indiced by malignancies, 10 of them with chronic inflammatory pericardial effusion
    Disease: Version SOC Term Classification Code Term Level
    9.1 10034474 Pericardial effusion PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-018275-20 Sponsor Protocol Number: UMCNONCO201001 Start Date*: 2010-03-24
    Sponsor Name:University Medical Centre Nijmegen St Radboud
    Full Title: A phase II study of cediranib as palliative treatment in patients with symptomatic malignant ascites or pleural effusion
    Medical condition: symptomatic malignant ascites or pleural effusion
    Disease: Version SOC Term Classification Code Term Level
    12.1 10025538 Malignant ascites LLT
    12.1 10026673 Malignant pleural effusion LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000599-40 Sponsor Protocol Number: Start Date*: 2012-06-13
    Sponsor Name:North Bristol NHS Trust
    Full Title: The efficacy of Indwelling Pleural Catheter placement versus IPC placement PLUS sclerosant (talc) in patients with malignant pleural effusions managed exclusively as out-patients
    Medical condition: Malignant pleural effusions
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10035605 Pleural mesothelioma malignant advanced PT
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10066721 Pleural effusion recurrent LLT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10035606 Pleural mesothelioma malignant localised LLT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10035607 Pleural mesothelioma malignant recurrent PT
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10035598 Pleural effusion PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10035608 Pleural metastases LLT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061352 Pleural neoplasm PT
    14.1 10042613 - Surgical and medical procedures 10035612 Pleural therapeutic procedures HLT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10035603 Pleural mesothelioma PT
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10046099 Unspecified pleural effusion LLT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10026673 Malignant pleural effusion PT
    14.1 10042613 - Surgical and medical procedures 10062754 Pleural cavity drainage LLT
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10014313 Effusion pleural LLT
    14.1 10042613 - Surgical and medical procedures 10068942 Implantable pleural catheter insertion PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10059518 Pleural mesothelioma malignant PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-000586-26 Sponsor Protocol Number: TIME3UK Start Date*: 2009-03-20
    Sponsor Name:University of Oxford
    Full Title: Adjuvant Urokinase in the Treatment of Malignant Pleural Effusion: The Third Therapeutic Intervention in Maligant Effusion Trial (TIME3-UK). A Randomised Controlled Trial to evaluate whether use of...
    Medical condition: Patients with malignant pleural effusions
    Disease: Version SOC Term Classification Code Term Level
    15.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10026673 Malignant pleural effusion PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-005123-32 Sponsor Protocol Number: SPON1030-11 Start Date*: 2013-04-17
    Sponsor Name:Cardiff University
    Full Title: Oral steroids for the resolution of otitis media with effusion in children study (OSTRICH)
    Medical condition: Otitis media with effusion.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004862 10040113 Serous otitis media (glue ear) LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005226-31 Sponsor Protocol Number: 1.1 Start Date*: 2006-04-24
    Sponsor Name:University of Oxford, Nuffield Department of Medicine
    Full Title: TIME 1 The First Therapeutic Intervention in Malignant Pleural Effusion Trial (TIME1) A 2 x 2 randomised factorial trial to assess whether non-steroidal anti-inflammatory analgesics and small bore...
    Medical condition: Malignant pleural effusion
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-003542-32 Sponsor Protocol Number: SCOPE Start Date*: 2020-02-28
    Sponsor Name:Dr. José Manuel Porcel Pérez
    Full Title: Randomised clinical trial: saline washouts versus standard treatment in complicated parapneumonic pleural effusion or empyema. SCOPE study.
    Medical condition: Treatment of complicated parapneumatic pleural effusion or empyema
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003137-25 Sponsor Protocol Number: ODAPE Start Date*: 2014-12-26
    Sponsor Name:José Manuel Porcel Pérez Hospital Arnau de Vilanova de Lleida Servicio Medicina Interna
    Full Title: Optimal duration of antibiotic treatment in patients with complicated parapneumonic pleural effusions or empyema: a randomized clinical trial
    Medical condition: Duration of antibiotic treatment in complicated parapneumonic pleural effusion and empyema.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003230-15 Sponsor Protocol Number: BEV-EFF Start Date*: 2006-10-17
    Sponsor Name:University Clinic Internal Medicine I
    Full Title: Phase I/II study investigating increasing doses of bevacizumab in patients with malignant effusion
    Medical condition: Malignant effusion in cancer patients requiring frequent centesis, at least two within six weeks
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-001121-24 Sponsor Protocol Number: P00804 Start Date*: 2011-04-21
    Sponsor Name:Papworth Hospital NHS Trust
    Full Title: Prospective randomised controlled trial of video assisted thorascopic (VATS) cytoreductive pleurectomy compared to talc pleurodesis in patients with suspected or proven malignant mesothelioma
    Medical condition: Mesothelioma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002221-35 Sponsor Protocol Number: P2013/PE1 Start Date*: 2014-12-18
    Sponsor Name:Hôpital Universitaire Des Enfants Reine Fabiola
    Full Title: Prospective Randomized Study Comparing the Efficacy and Safety of Pleural Drainage by Video-Assisted Thoracoscopic With Pleural Drain Associated With Urokinase in the Treatment of Parapneumonic Ple...
    Medical condition: Parapneumonic pleural effusion
    Disease: Version SOC Term Classification Code Term Level
    17.0 10021881 - Infections and infestations 10071699 Infectious pleural effusion PT
    17.0 10042613 - Surgical and medical procedures 10014569 Empyema drainage PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005122-23 Sponsor Protocol Number: 0683-056 Start Date*: 2008-08-06
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Phase II/III Randomized, Double-Blind Study of Paclitaxel plus Carboplatin in Combination with Vorinostat (MK-0683) or Placebo in Patients with Stage IIIB (with pleural effusion) or Stage IV Non-...
    Medical condition: Stage IIIB (with pleural effusion) or Stage IV Non-Small-Cell Lung Cancer (NSCLC)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10029521 Non-small cell lung cancer stage IIIB PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) DE (Prematurely Ended) FI (Prematurely Ended) DK (Prematurely Ended) GB (Prematurely Ended) SE (Prematurely Ended) IT (Prematurely Ended) LV (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-001795-37 Sponsor Protocol Number: AMB TS Start Date*: 2007-07-19
    Sponsor Name:Medical University Innsbruck, Dpt. Internal Medicine, Div. Internal Medicine
    Full Title: WIRKORTKONZENTRATIONEN VON AMPHOTERICIN B FORMULIERUNGEN IN ASZITES, LIQUOR, PLEURAERGUSS, GALLE UND LIQUOR BEI KRITISCH KRANKEN (Target-site concentrations of Amphotericin B preparations in ascit...
    Medical condition: Plasma and target-site (ascites, pleural effusion, bile and cerebrospinal fluid) concentrations of amphotericin B preparations will be measured in critically ill patients, requiring treatment with ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-001849-13 Sponsor Protocol Number: 2013/cardio3 Start Date*: 2013-07-09
    Sponsor Name:ASLTO2-Maria Vittoria Hospital Cardiology
    Full Title: AnakInRa Treatment of Recurrent Idiopathic Pericarditis
    Medical condition: idiopathic recurrent pericarditis
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-005065-38 Sponsor Protocol Number: ECHI-TS-2 Start Date*: 2014-02-17
    Sponsor Name:Medizinische Universität Innsbruck, Universitätsklinik für Innere Medizin I
    Full Title: Concentrations of echinocandins in ascites, pleural effusion, bile, wound secretion and cerebrospinal fluid – a pilot study
    Medical condition: Invasive fungal infection treated with an echinocandin and indication for paracentesis, thoracentesis, bile deviation or sampling, lumbar puncture or VAC therapy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011324-60 Sponsor Protocol Number: DE-09-RG-53 Start Date*: 2009-07-07
    Sponsor Name:Hannover Medical School
    Full Title: Prospective randomized trial to compare a twice daily to a once daily administration of the Tacrolimus in lung transplanted patients
    Medical condition: Patients ( ≥18 and ≤ 70 years) ≥ 1 year after single, double or heart/lung transplantation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-009134-32 Sponsor Protocol Number: 2137/09 Start Date*: 2009-04-27
    Sponsor Name:North Bristol NHS Trust
    Full Title: Bristol Randomised Controlled Trial of Zoledronic Acid in Malignant Pleural disease(Pilot Study).
    Medical condition: Malignant pleural disease of all histological cell types. 50% patients in trial will have indwelling pleural catheters for management of breathlessness.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001731-30 Sponsor Protocol Number: CDP791-002 Start Date*: 2005-07-25
    Sponsor Name:UCB Celltech
    Full Title: A Two-Part, Open Label Phase II Trial: Part One, Dose Escalation Safety; Part Two, Randomized/Comparing CDP791 (10 or 20 mg/kg) Plus Carboplatin/Paclitaxel With Carboplatin/Paclitaxel Alone in Sub...
    Medical condition: Non squamous non small cell lung cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2006-002688-26 Sponsor Protocol Number: BAY 43-9006 / 12006 Start Date*: 2007-02-12
    Sponsor Name:Bayer Healthcare AG, D-51368 Leverkusen, Germany
    Full Title: A Phase III Randomized, Double-blind, Placebo Controlled Trial Comparing the Efficacy of Gemcitabine, Cisplatin and Sorafenib to Gemcitabine, Cisplatin and Placebo in First-Line Treatment of Patien...
    Medical condition: The patient population includes patients with Stage IIIB (with effusion) or Stage IV NSCLC of non-squamos cell carcinoma subtype, with ECOG performance status 0 or 1, for whom treatment with gemci...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061873 Non-small cell lung cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) BE (Completed) FI (Completed) GR (Completed) AT (Completed) GB (Completed) IT (Completed) NL (Completed) HU (Prematurely Ended) ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-004051-19 Sponsor Protocol Number: IM101-042 Start Date*: 2005-05-13
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Phase IIB, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Abatacept in Combination Therapy with Glucocorticosteroids vs. Placebo plus Gluc...
    Medical condition: SYSTEMIC LUPUS ERYTHEMATOSUS, NOS
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) GB (Prematurely Ended) SE (Prematurely Ended) BE (Completed) AT (Completed) IT (Prematurely Ended)
    Trial results: Removed from public view
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