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Clinical trials for Epidermis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    34 result(s) found for: Epidermis. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2007-003106-99 Sponsor Protocol Number: ELBE II-2007 Start Date*: 2007-10-04
    Sponsor Name:University of Kiel, Department of Dermatology
    Full Title: Pimecrolimus and Epidermal Barrier Function: Role for pimecrolimus in restoring skin barrier function and normalizing epidermal lipid content and differentiation in atopic epidermis: a randomized, ...
    Medical condition: Investigative study of pathogenesis/treatment of calcineurin inhibitor vs. corticosteroid confirmatory study to prior study: Pimecrolimus and Epidermal Barrier Function, Protocol No. ELBE-2005, Eud...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-003917-17 Sponsor Protocol Number: BAK04 Start Date*: 2005-03-07
    Sponsor Name:Birken GmbH
    Full Title: Treatment of actinic keratoses with Birken-Oleogel in comparison to cryotherapy and the combination of cryotherapy plus Birken-Oleogel: a randomized, monocenter study. Behandlung aktinischer Kerat...
    Medical condition: Actinic keratoses. These are dysplasia of the epidermis caused by chronic UV-irradiation, that developwithout treatment in 20% of the cases into skin cancer (spinalioma). aktinische Keratosen. Die...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000726-78 Sponsor Protocol Number: SPD488-401 Start Date*: 2004-12-02
    Sponsor Name:Shire Pharmaceuticals Group plc
    Full Title: A 24 Week Randomised Double Blind Placebo Controlled Study to Evaluate the Atrophogenic Potential of Eflornithine in the Treatment of Women with Excessive Facial Hair
    Medical condition: Facial Hirsutism in Women
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-004824-11 Sponsor Protocol Number: ELBE-2005 Start Date*: 2005-04-15
    Sponsor Name:Universitätshautklinik Kiel
    Full Title: Role for pimecrolimus in restoring skin barrier function and normalizing epidermal lipid content and differentiation in atopic epidermis: a randomized, intra-patient, double-blind (right/left arm) ...
    Medical condition: Atopic Dermatitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000095-17 Sponsor Protocol Number: HOLOGENE17 Start Date*: 2017-08-17
    Sponsor Name:Holostem Terapie Avanzate s.r.l.
    Full Title: PROSPECTIVE, OPEN-LABEL, UNCONTROLLED CLINICAL TRIAL TO ASSESS THE SAFETY AND EFFICACY OF AUTOLOGOUS CULTURED EPIDERMAL GRAFTS CONTAINING EPIDERMAL STEM CELLS GENETICALLY MODIFIED WITH A GAMMA-RETR...
    Medical condition: JEB is genetically and clinically heterogeneous characterized by mutations in COL17A1,encoding for Collagen17 protein. COLXVII is a collagenous transmembrane type II protein component of the hemide...
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-004592-74 Sponsor Protocol Number: HOLOGENE7(HTA-HG7-01) Start Date*: 2016-06-01
    Sponsor Name:Holostem Terapie Avanzate s.r.l.
    Full Title: PROSPECTIVE, OPEN LABEL, UNCONTROLLED CLINICAL TRIAL TO ASSESS THE SAFETY AND EFFICACY OF AUTOLOGOUS CULTURED EPIDERMAL GRAFTS CONTAINING EPIDERMAL STEM CELLS GENETICALLY MODIFIED WITH A GAMMA-RETR...
    Medical condition: RDEB is characterized by generalized skin blistering, erosions, crusts, atrophic scarring, onychodystrophy and loss of nails, mutilating pseudosyndactyly of hands and feet, as well as oral cavity l...
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-004279-20 Sponsor Protocol Number: TUD-OCT-AD-025 Start Date*: 2007-11-14
    Sponsor Name:Technical University Dresden
    Full Title: Comparison of the atrophogenic effect of hydrocortisone 1% cream and Elidel (Pimecrolimus 1% cream) assessed by Optical Coherence Tomography (OCT) and 20-MHZ ultrasound of uninvolved skin in patien...
    Medical condition: patients with mild to moderate atopic dermatitis not affecting the test areas
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-005339-42 Sponsor Protocol Number: N16HPV Start Date*: 2016-08-30
    Sponsor Name:NKI-AVL
    Full Title: Safety, immunogenicity and clinical response of sig-HELP-E6SH/E7SH-kdel, injected in the epidermis by DNA tattoo, in HPV16-positive vulvar intraepithelial neoplasia: a phase I/II study
    Medical condition: HPV16+ usual type vulvar intraepithelial neoplasia (uVIN)
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016365-29 Sponsor Protocol Number: bcthug09 Start Date*: 2010-09-17
    Sponsor Name:MIGUEL CASARES FERNÁNDEZ-ALVÉS
    Full Title: Aplicación de células madre mesenquimales obtenidas de tejido adiposo del paciente quemado, para el tratamiento de la quemadura. Application of Mesenchymal Stem Cells in the management of the burn ...
    Medical condition: Tratamiento de las heridas por quemadura con ADMSC
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-006126-10 Sponsor Protocol Number: Efalizumab in CTCL Start Date*: 2008-11-27
    Sponsor Name:Charité - University Hospital Berlin
    Full Title: pilot study to evaluate the efficacy of Efalizumab in patients with cutaneous t-cell lymphoma
    Medical condition: The cutaneous T-cell lymphoma (also known as Sézary syndrome) is a common disorder of proliferated cells with characteristics of maligne t-lymphocytes immigrating from the cutaneous blood vessels t...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-002464-24 Sponsor Protocol Number: ESA-13/2010 Start Date*: 2011-07-15
    Sponsor Name:Dr. August Wolff GmbH & Co. KG Arzneimittel
    Full Title: Clinical study to investigate the efficacy and safety of an estradiol containing cream (0.01 % estradiol) in patients with dermatoporosis
    Medical condition: dermatoporosis stage I and II
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2021-003785-13 Sponsor Protocol Number: KTDIIS02 Start Date*: 2021-11-19
    Sponsor Name:Karolinska Universitetssjukhuset
    Full Title: An investigator-initiated, open label trial to investigate efficacy of brodalumab in eczematized psoriasis (BRodalumab in Eczematized PSOriasis)
    Medical condition: eczematized psoriasis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-000003-20 Sponsor Protocol Number: MEMPSOLAR0001 Start Date*: 2021-06-08
    Sponsor Name:Aarhus University Hospital
    Full Title: AN INVESTIGATOR INITIATED, PHASE 4, OPEN-LABEL, SINGLE-ARM, SINGLE-CENTER STUDY INVESTIGATING THE RESIDUAL DISEASE MEMORY IN PSORIASIS SKIN DURING ENSTILAR® AND NARROW-BAND ULTRAVIOLET B THERAPY. ...
    Medical condition: Psoriasis vulgaris
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000530-37 Sponsor Protocol Number: 24978 Start Date*: 2004-09-16
    Sponsor Name:Serono International S.A.
    Full Title: A multicentre, randomised, double blind, placebo controlled phase III study of subcutaneously administered onercept in the initial treatment and continued treatment after extended therapy in subjec...
    Medical condition: Psoriasis is an inflammatory skin disorder that affects between 1 and 2% of the population. It is characterised by an increased proliferation of the epidermis, and presents as well-defined thickene...
    Disease: Version SOC Term Classification Code Term Level
    7.0 10037153 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) LV (Completed) EE (Completed)
    Trial results: View results
    EudraCT Number: 2005-000897-38 Sponsor Protocol Number: DAM/001/05 Start Date*: 2005-05-18
    Sponsor Name:FARMACEUTICI DAMOR
    Full Title: Open-label, controlled, randomised, multicentre, parallel group clinical trial of efficacy and tolerability of Fitostimoline soaked gauzes, Fitostimoline cream and Citrizan gel in the topical...
    Medical condition: Topical treatment of second-degree superficial cutaneous burns
    Disease: Version SOC Term Classification Code Term Level
    6.1 10006802 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004664-23 Sponsor Protocol Number: ST 200 DS 05-01 Start Date*: 2006-05-25
    Sponsor Name:SIGMA-TAU
    Full Title: The role of Acetyl-L-Carnitine in Reflex Sympathetic Dystrophy RDS and in Complex Regional Pain Syndrome CRPS .Pilot clinical trial.
    Medical condition: Reflex Sympathetic Dystrophy RDS and Complex Regional Pain Syndrome CRPS .
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007825 Causalgia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2011-002339-24 Sponsor Protocol Number: NA Start Date*: 2012-05-25
    Sponsor Name:Barts and the London NHS Trust
    Full Title: Open label, single-centre study to evaluate the efficacy of the bradykinin (BK) B2 receptor antagonist, Icatibant, in the relief of symptoms resulting from moderate to severe angioedema unresponsiv...
    Medical condition: Idiopathic Angioedema
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-004304-12 Sponsor Protocol Number: 2260/2006 Start Date*: 2007-09-25
    Sponsor Name:AZIENDA OSPEDALIERA PISANA
    Full Title: Pilot study, randomised, open-label, monocentre, case vs control study to assess the effect of topically and parenterally Heparin administration treatment in superficial and deep second grade bu...
    Medical condition: Superficial and deep second degree burns.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006802 Burns second degree LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004397-96 Sponsor Protocol Number: CF20112018 Start Date*: 2019-04-09
    Sponsor Name:Merete Hædersdal
    Full Title: Impact of thermo-mechanical intervention on Protoporphyrin IX accumulation and biodistribution in normal skin following topical 5-aminolevulinic acid at high and low vehicle viscosity
    Medical condition: Healthy skin on the upper back on 3 participants in study a and 12 participants in study b.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-002285-12 Sponsor Protocol Number: OJ-KDC01 Start Date*: 2019-12-02
    Sponsor Name:LABORATORIO OJER PHARMA, S.L.
    Full Title: An exploratory, multicenter, randomized, open-label with blind evaluation, active-controlled study to evaluate the safety and efficacy of Keramod (imiquimod 50 mg/g, Gel) compared with Aldara (imi...
    Medical condition: ACTINIC QUERATOSIS, also known as solar keratosis, is a skin disease caused by chronic exposure to sunlight. It appears as scaly lesions on the skin as a result of an abnormal growth of the cells i...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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