Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Esmolol

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    13 result(s) found for: Esmolol. Displaying page 1 of 1.
    EudraCT Number: 2005-004617-15 Sponsor Protocol Number: ESPEKLILU05 rev. Start Date*: 2006-07-06
    Sponsor Name:Klinik für Anästhesiologie und Operative Intensivmedizin Klinikum Ludwigshafen
    Full Title: „Einsatz des Beta-Blockers Esmolol in Kombination mit dem Phosphodiesterase-III-Hemmer Enoximon im Vergleich zur alleinigen Gabe von Esmolol zur Optimierung der Hämodynamik bei Patienten mit korona...
    Medical condition: In einer prospektiven, monozentrischen, investigator-initiierten, randomisierten klinischen Prüfung sollen Patienten mit vorbestehender koronarer Herzkrankheit, die sich einem großen, elektiven all...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002366-23 Sponsor Protocol Number: AD-V1-05252015 Start Date*: 2015-10-13
    Sponsor Name:Medical University of Vienna, Department of Anaesthesia, General Intensive Care and Pain Management
    Full Title: Goal-directed heart rate control during emergence from anesthesia using esmolol to attenuate myocardial injury in patients undergoing non-cardiac surgery
    Medical condition: myocardial damage
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2021-003889-12 Sponsor Protocol Number: 3 Start Date*: 2022-01-20
    Sponsor Name:Consorcio Centro de Investigacion Biomedica en Red, M.P. (CIBER)
    Full Title: Prospective, multicenter and open study to evaluate the efficacy of esmolol in the early identification of cardiovascular disorders induced by cirrhosis, diabetes mellitus and cardiotoxic treatments.
    Medical condition: Cardiovascular disorders induced by cirrhosis, diabetes mellitus and cardiotoxic treatments.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003713-28 Sponsor Protocol Number: 2014-08 Start Date*: 2014-11-06
    Sponsor Name:Univeritetssjukhuset Örebro [...]
    1. Univeritetssjukhuset Örebro
    2. Universitetssjukhuset Örebro
    Full Title: What is the post operative opioid-reducing effect of the beta-receptor-agonist esmolol when administered during laparoscopic gastric by-pass surgery? Comparison between standard anesthesia and anes...
    Medical condition: Effect on post operative opioid consumption after laparoscopic gastric by-pass in obese
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000048-24 Sponsor Protocol Number: SE-CVC02/2013 Start Date*: 2013-03-28
    Sponsor Name:Hear Center of Semmelweis University
    Full Title: Randomised clinical trial evaluating the safety and effectiveness of esmolol and metoprolol for heart rate control of patients referred to coronary CT angiography
    Medical condition: Heart rate control of patients referred to coronary computed tomography angiography (CCTA) due to suspected coronary artery disease are to investigated with esmolol and metoprolol. Acquiring diagno...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021844-17 Sponsor Protocol Number: 33197 Start Date*: 2010-12-17
    Sponsor Name:Erasmus Medical Centre
    Full Title: Perioperative esmolol infusion for haemodynamic stability during major vascular surgery.
    Medical condition: cardiac complications during and after vascular surgery
    Disease: Version SOC Term Classification Code Term Level
    12.1 10028601 Myocardial ischemia LLT
    Population Age: Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-023311-34 Sponsor Protocol Number: CPA 368-10 Start Date*: 2011-02-04
    Sponsor Name:AOP Orphan Pharmaceuticals AG
    Full Title: A prospective, randomized, double blinded, crossover, two-treatment, two-sequence, short term pharmacokinetic, pharmacodynamic and tolerability, single centre study to compare AOP200704 vs. Esmolol...
    Medical condition: healthy male and female volunteers, intended for the treatment of dobutamine-induced tachycardia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10040752 Sinus tachycardia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2018-000680-93 Sponsor Protocol Number: SMILE Start Date*: 2018-06-05
    Sponsor Name:IRCCS ISTITUTO CLINICO HUMANITAS
    Full Title: Postoperative effects of high-dose esmolol during mitral valve surgery for mitral regurgitation.
    Medical condition: Patients undergoing mitral valve surgery.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10027716 Mitral insufficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-003012-31 Sponsor Protocol Number: 2011RC23r Start Date*: Information not available in EudraCT
    Sponsor Name:DIRECTION CENTRALE DU SERVICE DE SANTE DES ARMEES
    Full Title: Cardiovascular effects of esmolol alone and in combination with levosimendan during septic shock
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    18.0 10021881 - Infections and infestations 10040070 Septic shock PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012624-93 Sponsor Protocol Number: BREVI Start Date*: 2009-06-08
    Sponsor Name:OSPEDALE S. RAFFAELE
    Full Title: “Esmolol in cardiac surgery. A randomized controlled trial with clinical relevant endpoints.”
    Medical condition: patients undergoing cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020823 Hypertensive heart disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-023495-11 Sponsor Protocol Number: 2010-023495-11 Start Date*: 2010-12-17
    Sponsor Name:AZIENDA UNIVERSITARIA POLICLINICO UMBERTO I DI ROMA
    Full Title: Esmolol to treat tachicardia in septic shock
    Medical condition: septic shock
    Disease: Version SOC Term Classification Code Term Level
    9.1 10043071 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017356-28 Sponsor Protocol Number: PAW004 Start Date*: 2010-04-21
    Sponsor Name:University of Dundee
    Full Title: Evaluation of Beta Blockers for the Treatment of Asthma. A randomised controlled trial of propranolol.
    Medical condition: asthma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10003553 Asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-004512-22 Sponsor Protocol Number: P2018/568 Start Date*: 2019-02-18
    Sponsor Name:Erasme University Hospital
    Full Title: Effect of dexmedetomidine vs 0.9% sodium chloride on Nol-Index guided remifentanil analgesia: a double-blinded bicenter randomized controlled trial
    Medical condition: Intraoperative analgesia during general anesthesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Wed Jul 02 15:27:36 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA