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Clinical trials for Esomeprazole

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
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    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    72 result(s) found for: Esomeprazole. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2017-001284-20 Sponsor Protocol Number: BIOGIO Start Date*: 2017-07-05
    Sponsor Name:Erasmus MC Cancer Institute
    Full Title: The effects of the proton pump inhibitor esomeprazole on the bioavailability of afatinib (Giotrif®) in patients with non-small cell lung cancer (NSCLC) 'the BIO-GIO study'
    Medical condition: Non small cell lung cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005784-17 Sponsor Protocol Number: REGORA Start Date*: 2016-05-19
    Sponsor Name:Erasmus MC cancer institute
    Full Title: The effects of the proton pump inhibitor esomeprazole on the bioavailability of regorafenib in patients with a metastatic colorectal cancer (mCRC) or gastrointestinal stromal tumour (GIST).
    Medical condition: GIST and mCRC patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002441-39 Sponsor Protocol Number: D961DC00001 Start Date*: 2005-11-07
    Sponsor Name:AstraZeneca AB
    Full Title: A randomised, double-blind, parallel-group, placebo controlled study of esomeprazole i.v. (bolus infusion of 80 mg followed by a continuous infusion of 8 mg per hour) administered for 72 hours to a...
    Medical condition: Gatrointestinal haemorrhages NEC. (Bleeding gastric or duodenal ulcer will be investigated). MedDRA classification code Level: HLGT = High Level Group Term. See below.
    Disease: Version SOC Term Classification Code Term Level
    8.0 10017959 HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FI (Completed) SE (Completed) NO (Completed) DK (Completed) ES (Completed) AT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-004465-27 Sponsor Protocol Number: COCA Start Date*: 2018-02-01
    Sponsor Name:Erasmus MC Cancer Institute
    Full Title: The effects of the proton pump inhibitor esomeprazole alone or in combination with Coca-Cola on the absorption of Capecitabine in patients with colorectal cancer or other solid tumours ' the COCA s...
    Medical condition: Colorectal carcinoma or other solid tumours
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000334-30 Sponsor Protocol Number: INT27/14 Start Date*: 2014-09-17
    Sponsor Name:Fondazione IRCCS ''IStituto Nazionale dei Tumori''
    Full Title: Immunomodulatory effect of esomeprazole antitumoral and high-dose under neoadjuvant and adjuvant in patients with melanoma in stage III. Randomized pilot study treatment vs control
    Medical condition: metastatic melanoma BLS+ and BRAF wt
    Disease: Version SOC Term Classification Code Term Level
    16.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10025670 Malignant melanoma stage III PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-001160-29 Sponsor Protocol Number: SH-NEC-0002 Start Date*: 2012-03-08
    Sponsor Name:AstraZeneca AB
    Full Title: An Open Single-centre Study on the Pharmacokinetics and Pharmacodynamics of Esomeprazole After Once Daily Oral Administration for 7 Days in Preterm Infants and Neonates
    Medical condition: Gastraesdophageal Reflux Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10018203 GERD LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-000257-22 Sponsor Protocol Number: D9612L00104 Start Date*: 2006-07-03
    Sponsor Name:AstraZeneca UK Ltd
    Full Title: A study to assess the effectiveness of esomeprazole 40 mg once daily in subjects with continuing gastroesophageal reflux disease (GORD) symptoms following treatment with a previous full dose proton...
    Medical condition: Gastroesophageal Reflux Disease (GORD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-011865-10 Sponsor Protocol Number: FINA-004 Start Date*: Information not available in EudraCT
    Sponsor Name:MerLion Pharmaceuticals GmbH
    Full Title: An Open-label, Randomised, Multicentre, Multi-country Three-arm Study of the Treatment with Finafloxacin 400 mg b.i.d. plus Esomeprazole 40 mg b.i.d. for 14 days versus Finafloxacin 400 mg b.i.d. p...
    Medical condition: Helicobacter pylori infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019377 Helicobacter pylori infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) LT (Prematurely Ended) LV (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-000368-10 Sponsor Protocol Number: NEX-426-MEI-0040-I Start Date*: 2006-08-10
    Sponsor Name:Tecnical University of Munich
    Full Title: High-dose therapy with Esomeprazol in combination with Baclofen therapy for symptomatic therapy-resistant gastrooesophageal reflux disease.
    Medical condition: Gastroesophageal reflux disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-001156-19 Sponsor Protocol Number: D9614C00007 Start Date*: 2012-03-08
    Sponsor Name:AstraZeneca LP
    Full Title: A Randomized, Open-Label Study to Evaluate the Pharmacokinetics of Single Oral Doses of Esomeprazole Magnesium in Pediatric Patients 1 to 11 Years-Old Inclusive with Endoscopically-Proven Gastroeso...
    Medical condition: Pediatric patients 1 to 11 years old, inclusive, with endoscopically-proven GERD.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10017885 Gastrooesophageal reflux disease PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2012-001159-37 Sponsor Protocol Number: SH-NEC-0001 Start Date*: 2012-03-08
    Sponsor Name:AstraZeneca AB
    Full Title: A Single-Blind, Randomised, Parallel-Group, Single-Centre Pharmacokinetic and pH-Monitoring Study of Esomeprazole in Infants up to 24 Months of Age
    Medical condition: Gastroesophageal Reflux Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10018203 GERD LLT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2017-003777-34 Sponsor Protocol Number: NL63198.041.17 Start Date*: 2018-02-09
    Sponsor Name:UMC Utrecht
    Full Title: Proton pump inhibition for secondary hemochromatosis in hereditary anemia, a phase III placebo controlled randomized cross-over clinical trial.
    Medical condition: Iron overload (secondary hemochromatosis) in non-transfusion dependent forms of hereditary anemias. Iron overload and hereditary anemia are a growing, underestimated emerging health care problem.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004851 10002272 Anemia LLT
    20.0 100000004861 10057875 Secondary haemochromatosis LLT
    20.0 100000004861 10022979 Iron excess HLT
    20.0 100000004850 10055610 Hemoglobinopathy LLT
    20.0 100000004850 10074356 Non-transfusion dependent thalassemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2004-002370-39 Sponsor Protocol Number: D9614C00097 Start Date*: 2004-12-02
    Sponsor Name:ASTRAZENECA
    Full Title: A Phase III, Multicentre, Randomized, Double-blind Parallel-group Study to Evaluate the Safety and Clinical Outcome of Once Daily Esomeprazole for the Treatment of Gastroesophageal Reflux Disease ...
    Medical condition: Gastroesophageal Reflux Disease GERD
    Disease: Version SOC Term Classification Code Term Level
    6.1 10017885 PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2004-004748-27 Sponsor Protocol Number: Acadmed CTU01/05 Start Date*: 2005-02-21
    Sponsor Name:Hull and east Yorkshire Hospitals Trust, Research and Deveopment, admin porta cabin
    Full Title: An 8 week, double-blind, randomised, parallel group study to investigate the effect of 20 mg Esomeprazole (Nexium) tablets Twice daily versus placebo on symptoms associated with chronic cough due ...
    Medical condition: We will be using Nexium to treat gastro-oesophageal reflux and in return this will reduce reflux related cough ( a manifestation of reflux)
    Disease: Version SOC Term Classification Code Term Level
    3 10013946 2
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-001157-97 Sponsor Protocol Number: D9614C00099 Start Date*: 2012-03-08
    Sponsor Name:AstraZeneca AB
    Full Title: A Randomized, Open-Label Study to Evaluate the Pharmacokinetics of Multiple Doses of Esomeprazole Magnesium in a Pediatric Population of 1 to 11 Year olds with Gastroesophageal Reflux Disease (GERD...
    Medical condition: The target subject population was male and female children, aged 1 to 11 years inclusive, who suffered from GERD or symptoms of GERD and were candidates for acid suppression therapy.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10017885 Gastrooesophageal reflux disease PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-000574-69 Sponsor Protocol Number: D9612L00076 Start Date*: 2006-04-07
    Sponsor Name:AstraZeneca A/S
    Full Title: Development of an algorithm for identification of responders to short term treatment with esomeprazol (Nexium) in primary care.
    Medical condition: acid related disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-002515-21 Sponsor Protocol Number: D9612C09998 Start Date*: 2021-11-11
    Sponsor Name:AstraZeneca AB
    Full Title: "A Phase III Study to Assess the Efficacy and Safety of NEXIUM for Maintenance of Healing of Erosive Esophagitis in Pediatric Patients 1 to 11 Years of Age"
    Medical condition: Erosive Esophagitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004856 10063657 Erosive esophagitis LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: ES (Temporarily Halted) BE (Trial now transitioned) GR (Trial now transitioned) LT (Trial now transitioned) PT (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2004-005169-39 Sponsor Protocol Number: D9914C00002 Start Date*: 2005-08-11
    Sponsor Name:AstraZeneca AB
    Full Title: A single-blind single arm study to validate the Reflux Disease Questionnaire (RDQ) for the diagnosis of reflux disease in primary care in patients treated with esomeprazole 40 mg o.d.
    Medical condition: Symptoms from the upper gastrointestinal tract
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed) DE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-001158-25 Sponsor Protocol Number: D9614C00094 Start Date*: 2012-03-08
    Sponsor Name:AstraZeneca AB
    Full Title: A Randomized, Open-Label Study to Evaluate the Pharmacokinetics of Single and Multiple Doses of Esomeprazole Magnesium 20 mg and 40 mg in a Pediatric Population of 12 to 17 Year-Olds with Gastroeso...
    Medical condition: 12- to 17-year-olds inclusive with GERD or symptoms of GERD.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10017885 Gastrooesophageal reflux disease PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2021-000266-15 Sponsor Protocol Number: ESGIS Start Date*: 2021-09-29
    Sponsor Name:FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE
    Full Title: Effect of proton pump inhibitors on the structural integrity of endoscopic sleeve gastroplasty: a single-centre open-label, randomized, controlled pilot clinical trial
    Medical condition: Obesity is classified as a body mass index (BMI) above 30 kg/m2 by the World Health Organization
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10070972 Gastroplasty PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
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